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公开(公告)号：US20220152283A1
公开(公告)日：2022-05-19
申请号：US17438368
申请日：2020-03-11
申请人： ResuSciTec GmbH
发明人： Jürgen GRUDKE , Christoph BENK
摘要： The invention is a cooling unit for a heat exchanger, which preferably is a heat exchanger integrated in an oxygenator for the purpose of controlling the temperature of blood conveyed in an extracorporeal blood circuit. The cooling unit has a reservoir in which a liquid is stored, a reaction vessel comprises a reactant and which, in conjunction with the liquid, is able to initiate an endothermal reaction. A fluidic access is generated between the reservoir and the reaction vessel. A fluid line extends at least in part inside the reaction vessel which has an inlet line and outlet line, which are each connectable or connected in a fluid-tight manner to a hose system of the heat exchanger, which together with the hose system of the heat exchanger, provides least part of a fluid circuit.
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公开(公告)号：US20220111401A1
公开(公告)日：2022-04-14
申请号：US17245408
申请日：2021-05-26
申请人： Jin Wang KIM , Joung Ok LEE
发明人： Jin Wang KIM , Joung Ok LEE
摘要： A blood processing apparatus including a blood supply unit, a centrifuge, a light irradiation unit, a filtering device, and a blood collection unit, which is characterized in that blood is introduced into the centrifuge and centrifuged, the centrifuged blood is passed through a transparent tube provided in the light irradiation unit while being irradiated with light applied, from the outside of the transparent tube, by a light irradiation device configured to include an infrared lamp with a wavelength of 830±5 nm, a red light-emitting diode (LED) lamp with a wavelength of 635±6 nm, a blue LED lamp with a wavelength of 420±5 nm, a green LED lamp with a wavelength of 530±5 nm, a yellow LED lamp with a wavelength of 585±5 nm, and ultraviolet (UV) lamps, and the blood irradiated with the light is filtered using the filtering device and collected in the blood collection unit.
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公开(公告)号：US20220031921A1
公开(公告)日：2022-02-03
申请号：US17404956
申请日：2021-08-17
发明人： Roger Vertrees , Jan Winetz
摘要： An improved system and methods for treatment of cancer and other diseases including complications from late-stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed. The method can also be effective in treating rheumatoid arthritis, scleroderma, hepatitis, sepsis, the Epstein-Barr virus, and patients with life threatening complications from other viruses, including the COVID-19 virus. A method for removing viruses from the blood supply in an external circuit is also presented. An adjunct of the present invention is enhanced production of stem cells as a result of employing the HEATT process. A further adjunct is production of transgenic swine with extant viral infections.
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公开(公告)号：US11160912B2
公开(公告)日：2021-11-02
申请号：US16203483
申请日：2018-11-28
IPC分类号： A61M1/16 , A61M1/32 , B01D63/02 , F28D7/10 , F28D7/16 , F28F21/06 , A61M1/36 , F28D21/00 , F28F13/06
摘要： A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.
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公开(公告)号：US20210252205A1
公开(公告)日：2021-08-19
申请号：US17057191
申请日：2019-05-23
申请人： UNIVERSITA' DEGLI STUDI DI MILANO , FONDAZIONE IRCCS "CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO"
摘要： The present invention concerns an extracorporeal circuit for removing CO2 from blood comprising a blood withdrawal line for withdrawing blood from the patient, a filtration unit for producing plasma water and a line for returning the blood to the patient, defining a main circuit; the extracorporeal circuit further comprises a decarbonating group comprising a secondary circuit for the recirculation of plasma water, means for removing a fraction of said plasma water, a CO2 exchanger, a cationic resin charged with H+ ions set upstream of the CO2 exchanger and adapted to generate acid plasma water, means for the infusion of the acid plasma water upstream of the CO2 exchanger and means for the infusion of ions in a solution downstream of the CO2 exchanger.
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公开(公告)号：US10512716B2
公开(公告)日：2019-12-24
申请号：US15532639
申请日：2015-12-03
发明人： Stephen Turner
摘要： An oxygenation system for a ventilation system comprises an inlet for receiving oxygenation gas at an oxygenation gas flow rate into an oxygenator, and an exhaust gas remover to remove exhaust gas at an exhaust gas flow rate from the oxygenator, and one or more flow controllers for controlling the exhaust gas flow rate relative to the oxygenation gas flow rate. This allows the amount of total gas entering the oxygenator and the amount of total gas removed from the oxygenator to be controlled with greater accuracy.
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公开(公告)号：US20190331145A1
公开(公告)日：2019-10-31
申请号：US16398070
申请日：2019-04-29
发明人： Anna GALEA , Joseph Beuford Parse , Kylie Stengel , Kristen LeRoy , Minh Duong , Samuel Harrington Warner , Andrew Evan Kamholz , Brandon Johnson
摘要： Apparatuses for flowing multiple fluids in a single channel while substantially maintaining fluid separation are disclosed. In one configuration, the apparatus includes a first internal surface portion with an affinity to a first fluid and a second internal surface portion with an affinity to a second fluid. In another configuration, the apparatus includes a first fluid channel portion, a second fluid channel portion wrapped helically around the first fluid channel portion, and an opening therebetween. Also disclosed is an apparatus for maintaining substantially even fluid flow in fluid pathways having a first flow resistor portion, a second flow resistor portion, and a fluid channel therebetween.
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公开(公告)号：US10434238B2
公开(公告)日：2019-10-08
申请号：US15500835
申请日：2015-07-31
申请人： Xenios AG
发明人： Antonio Pesenti , Alberto Zanella , Domenico Salerno , Nicolò Antonino Patroniti , Francesco Mantegazza
摘要： The present invention relates to an extracorporeal circuit for CO2 removal from blood comprising a line for taking blood from the patient, a decarboxylation assembly and a line for returning the blood to the patient; said decarboxylation assembly comprising a first filtering unit, an oxygenator, an electrodialyzer adapted to generate an acid solution and a basic solution and means for the infusion of said acid solution upstream of said oxygenator, wherein said electrodialyzer comprises a first electrodialysis chamber and a second electrodialysis chamber, said first and second electrodialysis chambers being separated by an ionic membrane, and wherein said first chamber and said second chamber are respectively separated from the positive electrode, or anode, and from the negative electrode, or cathode, by means of a bipolar membrane.
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公开(公告)号：US10183145B2
公开(公告)日：2019-01-22
申请号：US15442393
申请日：2017-02-24
申请人： INCEPT, LLC
发明人： Yi Yang , Fred Khosravi , Lisa M. Young
IPC分类号： A61M25/00 , A61B17/22 , A61B17/3203 , A61F7/12 , A61F2/95 , A61M25/01 , A61M39/06 , A61M1/00 , A61M1/32 , A61M25/06 , A61B6/00 , A61B17/12 , A61M25/09 , A61M25/10 , B29C41/14 , A61L29/02 , A61L29/04 , A61L29/06 , A61L29/14 , A61M5/00 , A61B17/3207 , A61B17/00 , B29K27/18 , B29K75/00 , B29L31/00
摘要： A catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, adjacent windings of the coil spaced progressively further apart in the distal direction. An outer jacket surrounds the helical coil. The outer jacket is formed from a plurality of tubular segments positioned end to end, coaxially about the coil. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.
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10.发明申请公开(公告)号：US20190015578A1
公开(公告)日：2019-01-17
申请号：US15853848
申请日：2017-12-24
申请人： MARK S. SMYCZYNSKI
发明人： MARK S. SMYCZYNSKI
摘要： An exposure cell and method for treatment of carbon monoxide poisoning in the blood of a living body by removal of a portion of blood from the body, placing the portion in the exposure cell, exposing the portion in the cell to light of wave length and intensity that causes dissociation of carbon monoxide from hemoglobin, and returning the portion to the body. The exposure cell has an exposure zone outside of the body, that holds the portion, and a window that allows light from outside the zone to enter the zone to disassociate carbon monoxide from the portion. Oxygen is injected into the zone and carbon monoxide is removed from the zone.
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