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公开(公告)号：US20240358927A1
公开(公告)日：2024-10-31
申请号：US18647377
申请日：2024-04-26
发明人： Nitesh Ghananil Baviskar , Benjamin Cleveland , Sanjay Kumar Chandra , Katie Knowles , Junaid Mohammed Shaikh , Marshall O'Hearn
CPC分类号： A61M5/284 , A61M5/31511 , A61M5/3202
摘要： Mixing systems for producing a mixture to deliver to a treatment site. An illustrative system may comprise a needle hub, a multi-reservoir system, and a syringe. The multi-reservoir system may comprise a plunger assembly including a first plunger and a second plunger, a barrel portion including a housing defining a first reservoir in fluid communication with a first port and configured to contain a first constituent and a second reservoir configured to contain a second constituent and in fluid communication with a second port, and a cap including a port and a lumen extending therethrough. A third constituent may be injected from the syringe into the first reservoir via the port of the cap to form a precursor. Actuating the plunger assembly relative to the barrel portion may cause the precursor and the second constituent to be delivered into the needle hub.
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公开(公告)号：US20240358926A1
公开(公告)日：2024-10-31
申请号：US18293981
申请日：2022-08-03
申请人： SHL Medical AG
CPC分类号： A61M5/281 , A61M5/3243 , A61M2207/10
摘要： An expulsion assembly (100) of a medicament delivery device (102) for expelling medicament from a medicament container structure (250), the expulsion assembly comprising a container holder (125) having a container proximal end (212) and a container distal end (214), the container holder being configured to house the medicament container structure, and an axially extending needle cover (123), the needle cover having a needle cover proximal end (202) comprising a tubular shaped needle cover portion (206), and a needle cover distal end (204), wherein the container holder is at least partly enclosed by the needle cover, wherein a portion (121) of the outer surface of the container holder (125) and a portion (129) of the needle cover form an interface section (127) comprising an axially extending groove (220) and a protrusion (222) in which the container holder and the needle cover are arranged in abutment with each other.
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公开(公告)号：US12076519B2
公开(公告)日：2024-09-03
申请号：US17819735
申请日：2022-08-15
发明人： Lloyd M. Snyder
CPC分类号： A61M37/0069 , A61B17/3468 , A61K9/0024 , A61M5/28
摘要： A device for delivering a drug depot into a patient via a cannula is provided. The device includes a housing with a coupling mechanism. A drug cartridge is positioned within the housing and includes a cartridge depot channel having an occluding device that includes a ramp and a plateau. The occluding device occludes the cartridge depot channel to prevent the drug depot from moving beyond the occluding device without force applied to the drug depot sufficient to deflect the occluding device an amount to allow the drug depot to move beyond the occluding device. The drug cartridge includes an alignment boss with an end channel coaxial with the cartridge depot channel A push rod is slidably receivable in the housing and the drug cartridge to move the drug depot beyond the occluding device, into the cartridge depot channel, through the cannula and into the patient.
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公开(公告)号：US20240285860A1
公开(公告)日：2024-08-29
申请号：US18570586
申请日：2022-06-15
CPC分类号： A61M5/284 , A61M5/1409 , A61M5/14526 , A61M5/16827 , A61M5/19 , A61M2005/3128
摘要： Examples of the present application disclose a medication delivery apparatus comprising a first plunger, a second plunger and a container configured to receive the second plunger and at least a portion of the first plunger. The container and the second plunger define a dilution chamber that is configured to receive a diluent. The container defines a dilution chamber opening. The first plunger, the container and the second plunger define an active agent chamber that is configured to receive a pharmaceutical preparation. The second plunger comprises a one-way valve configured to control a flow of pharmaceutical preparation from the active agent chamber to the dilution chamber. The one-way valve is configured to move from a closed position to an open position upon application of a force exceeding a valve threshold force to an inlet side of the valve. The valve threshold force is less than a sum of a break loose force of the second plunger and a break loose force of the first plunger.
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公开(公告)号：US12048836B2
公开(公告)日：2024-07-30
申请号：US17048010
申请日：2019-04-18
申请人： SANOFI
发明人： Michael Helmer , Stefan Wendland
CPC分类号： A61M5/31501 , A61M5/2033 , A61M5/28 , A61M2005/2086 , A61M2005/3143
摘要： This application relates to force reduction in injection devices. According to a first aspect, the specification describes an injection device comprising: a medicament container; a stopper translatably disposed within the medicament container; a plunger rod, the plunger rod comprising a plunger head; a drive mechanism for displacing the plunger rod into the medicament container; and a force reduction feature, wherein the plunger rod is operable to displace the stopper; and wherein the force reduction feature is arranged to damp at least a part of a plunger rod motion when the plunger rod is driven by the drive mechanism.
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公开(公告)号：US12005236B2
公开(公告)日：2024-06-11
申请号：US16910640
申请日：2020-06-24
申请人： kaleo, Inc.
IPC分类号： A61M5/28 , A61M5/20 , A61M5/24 , A61M5/31 , A61M5/315 , A61M5/32 , G09B23/28 , G16H20/17 , G16H40/63
CPC分类号： A61M5/28 , A61M5/2053 , A61M5/2066 , G09B23/285 , G16H20/17 , G16H40/63 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/2093 , A61M5/24 , A61M5/2425 , A61M2005/3123 , A61M5/31501 , A61M5/3204 , A61M2205/50 , A61M2205/505 , A61M2205/581 , A61M2205/583 , A61M2205/80 , A61M2205/8206
摘要： An apparatus includes a housing, an actuator, a lock mechanism, and a medicament container. The lock mechanism selectively engages a portion of the housing such that (1) the lock mechanism is maintained in a substantially fixed position when the housing is in a first orientation and (2) the lock mechanism is removable from the housing when the housing is in a second orientation. The medicament container is moved in a proximal direction when the lock mechanism is removed from the housing to mix a first medicament portion contained within the medicament container with a second medicament portion contained within the medicament container. The actuator can be moved from a first position to a second position when the lock mechanism is removed from the housing to release energy stored within an energy storage member such that the medicament container is moved in a distal direction.
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公开(公告)号：US20240139416A1
公开(公告)日：2024-05-02
申请号：US18278701
申请日：2021-12-21
申请人： SHL MEDICAL AG
发明人： Daniel Carlsson
CPC分类号： A61M5/2053 , A61M5/2033 , A61M5/282 , A61M5/3234 , A61M5/326 , A61M5/5086 , A61M2005/2013 , A61M2005/3267
摘要： A medicament delivery device is presented having a mechanically flexible medicament container structure contained in a housing having a proximal end and a distal end, a hinge structure having two hinge arms, the hinge structure being arranged in the housing and configured to receive a portion of the medicament container structure between the two hinge arms, and a hollow drive member biased towards the proximal end and arranged distally relative to the hinge arms in the housing the drive member having an inner diameter which is smaller than a radial dimension of the hinge arms, wherein the drive member is configured to be released from a first axial position during a medicament delivery operation and move towards the proximal end of the housing, causing the drive member to move radially over the hinge arms which thereby move radially inwards towards each other to mechanically deform the portion of the medicament container structure for expulsion of medicament.
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公开(公告)号：US20240131269A1
公开(公告)日：2024-04-25
申请号：US18239055
申请日：2023-08-27
申请人： ALTAVIZ, LLC
发明人： John C. Huculak , Jack R. Auld , Hien Nguyen , Tammo Heeren , Matthew McCawley , Eric Anderfaas , John C. Dunne, JR.
CPC分类号： A61M5/31568 , A61F9/0008 , A61M5/24 , A61M5/281 , A61M5/3157 , A61M5/31581 , A61M2205/3306 , A61M2205/3317 , A61M2205/3368 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/584 , A61M2205/587
摘要： Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.
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公开(公告)号：US20240131266A1
公开(公告)日：2024-04-25
申请号：US18547460
申请日：2022-02-24
CPC分类号： A61M5/285 , A61M5/32 , A61M2207/10
摘要： A cartridge is configured to receive an injectable drug. The cartridge includes a body, and the body includes a proximal end portion having a proximal opening, a distal end portion having a distal opening, and a bore coupling the proximal opening and the distal opening. The cartridge further includes a pierceable septum coupled to the distal opening and a plunger movably carried within the bore. A volume is disposed in the bore between the pierceable septum and the plunger. The volume has a reduced pressure, and the reduced pressure is less than atmospheric pressure. A stopper is detachably coupled to the distal opening.
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公开(公告)号：US11957569B2
公开(公告)日：2024-04-16
申请号：US16804051
申请日：2020-02-28
CPC分类号： A61F2/148 , A61F2/142 , A61M5/281 , A61M5/315 , A61M5/31581 , A61M5/31596
摘要： A device and method for aspirating graft tissue and delivering the graft tissue to a target delivery site (for example, when performing Descemet's membrane endothelial keratoplasty). In one embodiment, an injector comprises a cylinder and a plunger at least partially located within the cylinder, the plunger being rotatably advanceable and retractable within the cylinder. In one aspect of the embodiment, rotating the plunger in a first direction within the cylinder controllably aspirates a graft tissue into the injector and rotating the plunger in a second direction opposite the first direction controllably ejects the graft tissue from the injector.
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