公开(公告)号：US20220032208A1

公开(公告)日：2022-02-03

申请号：US17277077

申请日：2019-10-08

申请人： ORGANO CORPORATION

发明人： Kazuo OKADA ,  Masahiro OGINO ,  Kohei SATO ,  Masaki TSURUTA ,  Toshiki MIYAJIMA

IPC分类号： B01D15/18 ,  G01N30/44

摘要： A simulated moving-bed type chromatographic separation method separating a weakly adsorptive component, a strongly adsorptive component, and an intermediately adsorptive component, with eluents by using a circulation system in which a plurality of unit packed columns packed with an adsorbent are connected in series and in an endless form via pipes in which a feed solution supply port F, two or more eluent supply ports D corresponding to the eluents, an extraction port A of a fraction containing the weakly adsorptive component, an extraction port B of a fraction containing the intermediately adsorptive component, and an extraction port C of a fraction containing the strongly adsorptive component are provided in the pipes of the circulation system, and positions of the ports F, A, B, and C are set to have a specified relationship.

公开(公告)号：US09149738B2

公开(公告)日：2015-10-06

申请号：US13866060

申请日：2013-04-19

申请人： Merck Patent GmbH

发明人： Romas Skudas

IPC分类号： B01D15/38 ,  B01D15/18 ,  G01N30/46 ,  G01N30/44

CPC分类号： B01D15/3804 ,  B01D15/1821 ,  B01D15/1871 ,  G01N30/44 ,  G01N30/461 ,  G01N30/468

摘要： The present invention is directed to a continuous affinity chromatography method and to an apparatus to be used in such method. The method allows the use of high operational velocity while maintaining high binding capacities.

摘要翻译： 本发明涉及一种连续亲和层析方法以及用于这种方法的装置。 该方法允许使用高操作速度同时保持高的结合能力。

公开(公告)号：US5039614A

公开(公告)日：1991-08-13

申请号：US539380

申请日：1990-06-15

申请人： Armenag Dekmezian ,  Tetsuya Morioka

发明人： Armenag Dekmezian ,  Tetsuya Morioka

IPC分类号： G01N1/18 ,  G01N1/40 ,  G01N15/02 ,  G01N30/00 ,  G01N30/02 ,  G01N30/30 ,  G01N30/44 ,  G01N30/74 ,  G01N30/80 ,  G01N30/84 ,  G01N30/88 ,  G01N35/00

CPC分类号： G01N30/84 ,  B01J20/291 ,  G01N1/18 ,  G01N1/40 ,  G01N35/00 ,  B01J2220/54 ,  G01N2001/4027 ,  G01N2030/027 ,  G01N2030/3084 ,  G01N2030/743 ,  G01N2030/8417 ,  G01N2030/8804 ,  G01N30/0005 ,  G01N30/02 ,  G01N30/44 ,  G01N30/80 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/25

摘要： An automated, on-line solvent elimination interface system is described for use in characterizing the Composition Distribution (CD) of unknown materials emerging from a fractionating unit or a process stream. Fractionated samples to be analyzed, such as a polymer, in highly diluted form in one or more solvents, are provided by a fractionation unit such as a gel permeation chromatograph (GPC), a high pressure liquid chromatograph (HPLC), or a field flow fractionator (FFF). A number of discharges of each particular fraction are supplied to individual collection units within the interface system under controlled conditions of flow rate, temperature and pressure (vacuum) such that the solvents are flash-evaporated at the collection unit. A sufficient solid residue is built up on the collection unit for analysis by, for example, a Fourier transform infrared (FTIR) analyzer.

摘要翻译： 描述了一种自动化的在线溶剂消除界面系统，用于表征从分馏单元或工艺流出现的未知材料的组成分布（CD）。 通过分离单元例如凝胶渗透色谱仪（GPC），高压液相色谱仪（HPLC）或场流（HPLC）提供在一种或多种溶剂中以高度稀释的形式分析的分析样品，例如聚合物， 分馏器（FFF）。 在流量，温度和压力（真空）的受控条件下，将各种特定级分的多次放电提供给接口系统内的各个收集单元，使得溶剂在收集单元处闪蒸。 在收集单元上建立了足够的固体残留物，用于通过例如傅里叶变换红外（FTIR）分析仪进行分析。

公开(公告)号：US4970085A

公开(公告)日：1990-11-13

申请号：US423921

申请日：1989-10-19

申请人： Louis T. Persson ,  Lester P. Van Brocklin ,  Lowen R. Morrison, Jr. ,  Claudia A. Smith ,  Donald R. Meece

发明人： Louis T. Persson ,  Lester P. Van Brocklin ,  Lowen R. Morrison, Jr. ,  Claudia A. Smith ,  Donald R. Meece

IPC分类号： A23L2/80 ,  A23L27/12 ,  G01N30/44

CPC分类号： A23L2/80 ,  A23L27/13 ,  G01N30/44

摘要： The invention is a method for making improved citrus aqueous essences by a fractionation process wherein citrus aqueous essence is first passed through a solid adsorbent so that part of the essence compounds exit the adsorbent in a first effluent and part remain on the adsorbent, and then at least part of the first effluent is recycled through the adsorbent to recover a fraction of the remaining compounds and produce a second effluent.

公开(公告)号：US4150563A

公开(公告)日：1979-04-24

申请号：US851783

申请日：1977-11-15

申请人： Milan Minarik ,  Milan Popl ,  Jiri Mostecky

发明人： Milan Minarik ,  Milan Popl ,  Jiri Mostecky

IPC分类号： G01N30/44 ,  G01N31/08

CPC分类号： G01N30/44

摘要： Method of and appartus for liquid recirculation in at least substantially closed circuit which is particularly suitable for recycled liquid chromatography. The circulating liquid is brought into motion in the circuit inlet by working fluid supplied under pressure, e.g. from a pump, pressure gas cylinder, or the like. Circulating liquid approaching the end of the circuit beyond the circuit outlet is mechanically and at regular intervals repeatedly transported in the form of slugs into the beginning of the circuit in advance of the circuit inlet where these slugs are again forced into the circuit inlet by means of working fluid. The injection of one slug into the circuit inlet and the pushing of the following slug of equal volume out from the circuit outlet are carried out simultaneously.

摘要翻译： 在至少基本封闭的电路中进行液体再循环的方法和装置，其特别适用于再循环液相色谱。 循环液体通过在压力下供给的工作流体在电路入口中运动。 来自泵，压力气瓶等。 在电路出口之外接近电路端部的循环液体以机械方式并且以规则的间隔重复地以电池形式传输到电路的开头，在电路入口之前，这些电池块再次被迫进入电路入口，借助于 工作流体 将一个塞子注入电路入口并从电路出口推出等体积的以下塞子同时进行。

公开(公告)号：US3533220A

公开(公告)日：1970-10-13

申请号：US3533220D

申请日：1967-02-13

申请人： AQUITAINE PETROLE

发明人： ESPAGNO LUCIEN ,  BLANC CLAUDE ,  HUYNH CHANH TRUNG

IPC分类号： B01D59/26 ,  G01N30/02 ,  G01N30/44 ,  G01N30/46 ,  G01N30/72 ,  G01N30/80 ,  G01N30/82 ,  G01N30/84 ,  G01N30/86 ,  B01D57/00

CPC分类号： G01N30/84 ,  B01D59/26 ,  G01N30/44 ,  G01N30/461 ,  G01N30/7206 ,  G01N30/80 ,  G01N30/82 ,  G01N30/8631 ,  G01N2030/025 ,  G01N2030/445 ,  B01D59/00

公开(公告)号：US3455090A

公开(公告)日：1969-07-15

申请号：US3455090D

申请日：1967-03-06

申请人： PHILLIPS PETROLEUM CO

发明人： DEFORD DONALD D

IPC分类号： G01N30/44 ,  B01D15/08

CPC分类号： G01N30/44

公开(公告)号：US3174326A

公开(公告)日：1965-03-23

申请号：US71725858

申请日：1958-02-24

申请人： BECKMAN INSTRUMENTS INC

发明人： CARLE DON W ,  BURNELL MAURICE R

IPC分类号： G01N30/14 ,  G01N30/32 ,  G01N30/44 ,  G01N30/46 ,  G01N30/60

CPC分类号： G01N30/466 ,  G01N30/14 ,  G01N30/32 ,  G01N30/44 ,  G01N30/6043

公开(公告)号：US3155468A

公开(公告)日：1964-11-03

申请号：US77296158

申请日：1958-11-10

申请人： AIR LIQUIDE

发明人： DE MONTGAREUIL PIERRE GUERIN ,  DANIEL DOMINE

IPC分类号： B01D53/04 ,  B01D53/047 ,  B01D53/14 ,  G01N30/44 ,  G01N30/46

CPC分类号： G01N30/468 ,  B01D53/04 ,  B01D53/0476 ,  B01D53/14 ,  B01D2253/108 ,  B01D2256/10 ,  B01D2256/12 ,  B01D2257/102 ,  B01D2257/104 ,  G01N30/44

公开(公告)号：US20240219356A1

公开(公告)日：2024-07-04

申请号：US18557853

申请日：2022-03-31

申请人： K.D. PHARMA BEXBACH GMBH

发明人： Gideon GIESSELMANN ,  Roberto FRONZONI ,  Elia RAMOS-TERCERO ,  Denitsa SHOPOVA-GOSPODINOVA ,  Bruno CALLA

IPC分类号： G01N30/44 ,  G01N30/02

CPC分类号： G01N30/44 ,  G01N2030/027

摘要： This version will replace all prior versions in the application: A chromatography method in which a starting material is separated into fractions and at least one of the fractions which have at least a predetermined target content of at least one target component of the starting material is derived as a target product fraction. The fractions which do not have the predetermined target content form residual fractions and at least part of at least one of the residual fractions is added to the starting material still to be separated. At least part of at least one of the residual fractions of which the content of the target component differs less from the predetermined target content than the target component content of the starting material is added to the starting material still to be separated. The residual fractions of which the target component content differs more from the predetermined target content than that of the starting material are diverted for further handling.