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    INJECTABLE RESORBABLE CERAMIC COMPOSITIONS
    3.
    发明申请
    INJECTABLE RESORBABLE CERAMIC COMPOSITIONS 审中-公开
    可重复使用的陶瓷组合物

    公开(公告)号：WO2008048182A1

    公开(公告)日：2008-04-24

    申请号：PCT/SE2007/050745

    申请日：2007-10-16

    Applicant: DOXA AB ,  HERMANSSON, Leif ,  ENGQVIST, Håkan

    Inventor： HERMANSSON, Leif ,  ENGQVIST, Håkan

    IPC: A61L24/02 ,  A61K6/06 ,  A61L27/10

    CPC classification number: A61L24/0042 ,  A61L24/02 ,  A61L27/306 ,  A61L27/58 ,  A61L2400/06 ,  C04B28/344 ,  C04B2111/00836 ,  C04B11/28 ,  C04B14/043 ,  C04B14/366 ,  C04B22/143

    Abstract: The present invention relates to a ceramic precursor composition for resorbable or partly resorbable high-strength bioelements, wherein the precursor composition comprises 40-70 wt-% of one or more silicate with Ca as the main cation, 40-20 wt- % of a Ca-sulphate, and greater than 0 wt-% to less than 10 wt-% of an acidic soluble Ca-salt, the remainder, if any, comprises additives. The invention also relates to a slurry, a cured material, a medical implant, and a carrier material for drug delivery made from said precursor composition, as well as a method of manufacturing said a cured chemically bonded ceramic material.

    Abstract translation: 本发明涉及一种用于可再吸收或部分可再吸收的高强度生物元素的陶瓷前体组合物，其中前体组合物包含40-70重量％的一种或多种硅酸盐，其中Ca作为主要阳离子，40-20重量％ 并且大于0重量％至小于10重量％的酸性可溶性Ca-盐，其余部分（如果有的话）包含添加剂。 本发明还涉及由所述前体组合物制成的用于药物递送的浆料，固化材料，医用植入物和载体材料，以及制造所述固化的化学键合的陶瓷材料的方法。

    IMPLANT AND METHOD OF PRODUCING THE SAME, AND A SYSTEM FOR IMPLANTATION
    4.
    发明申请
    IMPLANT AND METHOD OF PRODUCING THE SAME, AND A SYSTEM FOR IMPLANTATION 审中-公开
    植入物及其生产方法，以及植入系统

    公开(公告)号：WO2005053764A1

    公开(公告)日：2005-06-16

    申请号：PCT/SE2004/001745

    申请日：2004-11-25

    Applicant: DOXA AB ,  HERMANSSON, Leif ,  ENGQVIST, Håkan ,  LÖÖF, Jesper

    Inventor： HERMANSSON, Leif ,  ENGQVIST, Håkan ,  LÖÖF, Jesper

    IPC: A61L27/30

    CPC classification number: A61L27/306 ,  A61K6/0631 ,  B82Y30/00 ,  C04B35/22 ,  C04B35/44 ,  C04B41/009 ,  C04B41/5024 ,  C04B41/5032 ,  C04B41/85 ,  C04B2111/00836 ,  C04B2235/3205 ,  C04B2235/781 ,  C04B35/10 ,  C04B35/48

    Abstract: The present invention relates to a coated implant for in vivo-anchoring of implants to a biological tissue or another implant, which coated implant comprises an implant having a pre-treated surface and on said pre-treated surface one or more layers of ceramic material chemically and/or mechanically bound to said pre-treated surface. Said one or more layers comprises mainly non-hydrated chemically bonded ceramic material, and each layer independently comprises a first binder phase selected from the group consisting of aluminates, silicates, phosphates, sulphates and combinations thereof. The invention further relates to method of manufacturing said coated implant, a ceramic paste and to a kit comprising said coated implant and ceramic paste. The invention is particularly suitable for dental and orthopaedic implants.

    Abstract translation: 本发明涉及用于将植入物体内锚定到生物组织或另一种植入物上的涂层植入物，该涂层植入物包括具有预处理表面的植入物和所述预处理表面上的植入物 一层或多层陶瓷材料化学地和/或机械地结合到所述预处理过的表面上。 所述一个或多个层主要包含非水合的化学键合的陶瓷材料，并且各层独立地包含选自铝酸盐，硅酸盐，磷酸盐，硫酸盐及其组合的第一粘结相。 本发明进一步涉及制造所述涂覆的植入物的方法，陶瓷膏以及包括所述涂覆的植入物和陶瓷膏的套件。 本发明特别适用于牙科和整形外科植入物。

    CHEMICALLY BONDED CERAMIC MATERIAL BASED ON TRI CALCIUM OXIDE ALUMINIUM OXIDE (C3A), POWDER AND PASTE FOR FORMING SAME, AND USE THEREOF
    5.
    发明申请
    CHEMICALLY BONDED CERAMIC MATERIAL BASED ON TRI CALCIUM OXIDE ALUMINIUM OXIDE (C3A), POWDER AND PASTE FOR FORMING SAME, AND USE THEREOF 审中-公开
    基于三氧化二铝氧化铝（C3A），粉末和粉末形成的化学键合陶瓷材料及其使用

    公开(公告)号：WO2011065873A1

    公开(公告)日：2011-06-03

    申请号：PCT/SE2009/051331

    申请日：2009-11-24

    Applicant: DOXA AB ,  HERMANSSON, Leif ,  BERGMAN, Helena

    Inventor： HERMANSSON, Leif ,  BERGMAN, Helena

    IPC: A61K6/06 ,  A61L24/02 ,  A61L27/10

    CPC classification number: A61L24/0068 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0038 ,  A61K6/06 ,  A61K6/083 ,  A61L2430/12 ,  C08L33/08

    Abstract: The present invention relates to a chemically bonded ceramic material based on 3CaO•Al 2 O 3 (also denoted as C 3 A) and its use in applications wherein the ambient temperature during hydration is above 25°C. The main binder system forms a chemically bonded ceramic upon hydration thereof and is based onpowdered calcium aluminate, and may optionally contain minor amounts of other phases ofcalcium aluminate and/or calcium silicate. An optimal second binder system is a crosslinking organic binder system which provides for initial crosslinking of the freshly mixed paste forming the biomaterial. The material also comprises inert filler particles. The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic material, and a paste from which the material is formed, as well as a kit comprising the powdered composition and liquid, as well as methods of using the material as a biomaterial in small volume applications, and the use of the general material as a construction material.

    Abstract translation: 本发明涉及一种基于3CaO°Al2O3（也称为C3A）的化学键合陶瓷材料及其在水合时的环境温度高于25℃的应用中的用途。 主要的粘合剂体系在其水合时形成化学键合的陶瓷，并且基于粉末状的铝酸钙，并且可以任选地含有少量的铝酸钙和/或硅酸钙的其它相。 最佳的第二粘合剂体系是交联有机粘合剂体系，其提供形成生物材料的新混合糊料的初始交联。 该材料还包括惰性填料颗粒。 本发明涉及一种用于制备本发明的化学键合的陶瓷材料的粉末组合物，以及形成该材料的糊料，以及包含粉末状组合物和液体的试剂盒，以及将该材料用作生物材料的方法 小批量应用，并将一般材料用作建筑材料。

    SIMPLIFIED CHEMICALLY BONDED CERAMIC BIOMATERIAL COMPRISING TWO BINDER SYSTEMS
    6.
    发明申请
    SIMPLIFIED CHEMICALLY BONDED CERAMIC BIOMATERIAL COMPRISING TWO BINDER SYSTEMS 审中-公开
    包含两个绑定系统的简化化学结合的陶瓷生物材料

    公开(公告)号：WO2011043707A1

    公开(公告)日：2011-04-14

    申请号：PCT/SE2009/051135

    申请日：2009-10-09

    Applicant: DOXA AB ,  HERMANSSON, Leif ,  LÖÖF, Jesper ,  FARIS, Adam

    Inventor： HERMANSSON, Leif ,  LÖÖF, Jesper ,  FARIS, Adam

    IPC: A61L24/00 ,  A61L27/10 ,  A61L27/44 ,  A61K6/06 ,  C04B24/04 ,  C04B28/00

    CPC classification number: A61L27/446 ,  A61K6/0205 ,  A61K6/0835 ,  A61L24/0089 ,  A61L27/10 ,  C04B28/06 ,  C04B2111/00836 ,  C04B7/02 ,  C04B14/22 ,  C04B20/008 ,  C04B22/124 ,  C04B24/04 ,  C04B24/2641

    Abstract: The present invention generally relates to chemically bonded ceramic biomaterials, preferably a dental material or an implant material, comprising two binder systems. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and, optionally, minor amounts of calcium silicate. The second binder system is a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste forming the biomaterial. The biomaterial also comprises inert filler particles. The inventive biomaterial is free from reactive glass and thus provides for a simplified two binder systems biomaterial with a reduced number of required reactive components The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications.

    Abstract translation: 本发明通常涉及化学结合的陶瓷生物材料，优选牙科材料或植入材料，其包含两种粘合剂体系。 主要的粘合剂体系在水合时形成化学键合的陶瓷，并且包括粉末状的铝酸钙和任选地少量的硅酸钙。 第二粘合剂系统是交联的有机粘合剂体系，其提供形成生物材料的新混合糊料的初始交联。 生物材料还包括惰性填料颗粒。 本发明的生物材料不含活性玻璃，因此提供了一种具有减少数量的所需反应性组分的简化的两种粘合剂体系生物材料。本发明涉及用于制备本发明化学键合的陶瓷生物材料的粉末组合物，以及生物材料 形成，以及包含粉末状组合物和水合液体的试剂盒，以及生物材料在牙齿和植入物应用中的方法和用途。

    DENTAL CEMENT SYSTEM
    8.
    发明申请
    DENTAL CEMENT SYSTEM 审中-公开
    牙科水泥系统

    公开(公告)号：WO2009025599A1

    公开(公告)日：2009-02-26

    申请号：PCT/SE2007/050574

    申请日：2007-08-23

    Applicant: DOXA AB ,  HERMANSSON, Leif ,  LÖÖF, Jesper ,  ENGQVIST, Håkan

    Inventor： HERMANSSON, Leif ,  LÖÖF, Jesper ,  ENGQVIST, Håkan

    IPC: A61K6/06

    CPC classification number: A61K6/0008 ,  A61K6/0023 ,  A61K6/0631 ,  A61K6/0675 ,  C08L33/08 ,  A61K6/0835

    Abstract: A dental cement system, comprising an aqueous hydration liquid and a powdered material that essentially consists of an inorganic cement system, which powdered material has the capacity to form a complex, chemically bonded material with inorganic as well as organic phases with properties suitable for cementation of implant to another implant and/or to tooth or bone tissue. The invention relates to the powdered material and the hydration liquid, respectively, as well as the formed ceramic material and a kit comprising the system.

    Abstract translation: 一种牙科水泥系统，包括水性水合液体和基本上由无机水泥体系组成的粉末材料，该粉末材料具有与无机和有机相形成复合化学键合的材料的能力，其特性适合于 植入到另一植入物和/或牙齿或骨组织。 本发明分别涉及粉末材料和水合液体，以及形成的陶瓷材料和包括该系统的试剂盒。

    IMPLANT AND METHOD OF PRODUCING THE SAME, AND A SYSTEM FOR IMPLANTATION
    10.
    发明申请
    IMPLANT AND METHOD OF PRODUCING THE SAME, AND A SYSTEM FOR IMPLANTATION 审中-公开
    植入物及其制造方法以及植入系统

    公开(公告)号：WO2005053764A8

    公开(公告)日：2005-07-28

    申请号：PCT/SE2004001745

    申请日：2004-11-25

    Applicant: DOXA AB ,  HERMANSSON LEIF ,  ENGQVIST HAAKAN ,  LOEOEF JESPER

    Inventor： HERMANSSON LEIF ,  ENGQVIST HAAKAN ,  LOEOEF JESPER

    IPC: A61K6/06 ,  A61L27/30 ,  C04B35/22 ,  C04B35/44 ,  C04B41/50 ,  C04B41/85 ,  A61K6/027 ,  C04B7/32 ,  C04B41/52

    CPC classification number: A61L27/306 ,  A61K6/0631 ,  B82Y30/00 ,  C04B35/22 ,  C04B35/44 ,  C04B41/009 ,  C04B41/5024 ,  C04B41/5032 ,  C04B41/85 ,  C04B2111/00836 ,  C04B2235/3205 ,  C04B2235/781 ,  C04B35/10 ,  C04B35/48

    Abstract: The present invention relates to a coated implant for in vivo-anchoring of implants to a biological tissue or another implant, which coated implant comprises an implant having a pre-treated surface and on said pre-treated surface one or more layers of ceramic material chemically and/or mechanically bound to said pre-treated surface. Said one or more layers comprises mainly non-hydrated chemically bonded ceramic material, and each layer independently comprises a first binder phase selected from the group consisting of aluminates, silicates, phosphates, sulphates and combinations thereof. The invention further relates to method of manufacturing said coated implant, a ceramic paste and to a kit comprising said coated implant and ceramic paste. The invention is particularly suitable for dental and orthopaedic implants.

    Abstract translation: 本发明涉及一种用于将植入物体内锚定到生物组织或另一种植入物的涂覆植入物，所述涂覆的植入物包括具有预处理表面的植入物，并且在所述预处理的表面上具有化学上的一层或多层陶瓷材料 和/或机械地结合到所述预处理的表面上。 所述一层或多层主要包含非水合化学键合的陶瓷材料，并且每层独立地包括选自铝酸盐，硅酸盐，磷酸盐，硫酸盐及其组合的第一粘结相。 本发明还涉及制造所述涂覆的植入物的方法，陶瓷膏和包括所述涂覆的植入物和陶瓷糊的试剂盒。 本发明特别适用于牙科和矫形植入物。

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