ANTIPATHOGENIC BIOMEDICAL IMPLANTS, METHODS AND KITS EMPLOYING PHOTOCATALYTICALLY ACTIVE MATERIAL
    1.
    发明申请
    ANTIPATHOGENIC BIOMEDICAL IMPLANTS, METHODS AND KITS EMPLOYING PHOTOCATALYTICALLY ACTIVE MATERIAL 审中-公开
    抗生素生物医学植入物,使用光化学活性材料的方法和工具

    公开(公告)号:WO2009104168A2

    公开(公告)日:2009-08-27

    申请号:PCT/IB2009/050715

    申请日:2009-02-20

    Abstract: An antipathogenic biomedical implant is formed throughout its structure of a matrix material comprising at least about 1 weight percent of a photocatalytically active filler which exhibits an antipathogenic effect upon irradiation with light. The photocatalytically active filler is arranged in the matrix material in the implant to receive light irradiated from an external light source. In another embodiment, an antipathogenic biomedical implant comprises at least about 1 weight percent of a photocatalytically active material which exhibits an antipathogenic effect upon irradiation with light, wherein the photocatalytically active material is arranged in the implant to receive light irradiated from an external light source. Methods for providing an antipathogenic biomedical implant, methods for reducing pathogens on a biomedical implant, methods for reducing the bioburden in a biomedical implant installation, and kits for providing an antipathogenic biomedical implant employ the antipathogenic biomedical implants.

    Abstract translation: 在其基质材料的整个结构中形成抗病原生物医学植入物,其包含至少约1重量%的光催化活性填料,其在用光照射时表现出抗病原作用。 将光催化活性填料布置在植入物中的基质材料中以接收从外部光源照射的光。 在另一个实施方案中,抗病原生物医学植入物包含至少约1重量%的光催化活性材料,其在照射光时表现出抗病原作用,其中光催化活性物质被布置在植入物中以接收从外部光源照射的光。 用于提供抗病原生物医学植入物的方法,用于减少生物医学植入物上的病原体的方法,用于减少生物医学植入物装置中的生物负载的方法以及用于提供抗病原性生物医学植入物的试剂盒使用抗病原生物医学植入物。

    INJECTABLE RESORBABLE CERAMIC COMPOSITIONS
    2.
    发明申请
    INJECTABLE RESORBABLE CERAMIC COMPOSITIONS 审中-公开
    可重复使用的陶瓷组合物

    公开(公告)号:WO2008048182A1

    公开(公告)日:2008-04-24

    申请号:PCT/SE2007/050745

    申请日:2007-10-16

    Abstract: The present invention relates to a ceramic precursor composition for resorbable or partly resorbable high-strength bioelements, wherein the precursor composition comprises 40-70 wt-% of one or more silicate with Ca as the main cation, 40-20 wt- % of a Ca-sulphate, and greater than 0 wt-% to less than 10 wt-% of an acidic soluble Ca-salt, the remainder, if any, comprises additives. The invention also relates to a slurry, a cured material, a medical implant, and a carrier material for drug delivery made from said precursor composition, as well as a method of manufacturing said a cured chemically bonded ceramic material.

    Abstract translation: 本发明涉及一种用于可再吸收或部分可再吸收的高强度生物元素的陶瓷前体组合物,其中前体组合物包含40-70重量%的一种或多种硅酸盐,其中Ca作为主要阳离子,40-20重量% 并且大于0重量%至小于10重量%的酸性可溶性Ca-盐,其余部分(如果有的话)包含添加剂。 本发明还涉及由所述前体组合物制成的用于药物递送的浆料,固化材料,医用植入物和载体材料,以及制造所述固化的化学键合的陶瓷材料的方法。

    IMPLANT AND METHOD OF PRODUCING THE SAME, AND A SYSTEM FOR IMPLANTATION
    3.
    发明申请
    IMPLANT AND METHOD OF PRODUCING THE SAME, AND A SYSTEM FOR IMPLANTATION 审中-公开
    植入物及其生产方法,以及植入系统

    公开(公告)号:WO2005053764A1

    公开(公告)日:2005-06-16

    申请号:PCT/SE2004/001745

    申请日:2004-11-25

    Abstract: The present invention relates to a coated implant for in vivo-anchoring of implants to a biological tissue or another implant, which coated implant comprises an implant having a pre-treated surface and on said pre-treated surface one or more layers of ceramic material chemically and/or mechanically bound to said pre-treated surface. Said one or more layers comprises mainly non-hydrated chemically bonded ceramic material, and each layer independently comprises a first binder phase selected from the group consisting of aluminates, silicates, phosphates, sulphates and combinations thereof. The invention further relates to method of manufacturing said coated implant, a ceramic paste and to a kit comprising said coated implant and ceramic paste. The invention is particularly suitable for dental and orthopaedic implants.

    Abstract translation: 本发明涉及用于将植入物体内锚定到生物组织或另一种植入物上的涂层植入物,该涂层植入物包括具有预处理表面的植入物和所述预处理表面上的植入物 一层或多层陶瓷材料化学地和/或机械地结合到所述预处理过的表面上。 所述一个或多个层主要包含非水合的化学键合的陶瓷材料,并且各层独立地包含选自铝酸盐,硅酸盐,磷酸盐,硫酸盐及其组合的第一粘结相。 本发明进一步涉及制造所述涂覆的植入物的方法,陶瓷膏以及包括所述涂覆的植入物和陶瓷膏的套件。 本发明特别适用于牙科和整形外科植入物。

    STORAGE STABLE PREMIXED HYDRAULIC CEMENT COMPOSITIONS, CEMENTS, METHODS, AND ARTICLES
    5.
    发明申请
    STORAGE STABLE PREMIXED HYDRAULIC CEMENT COMPOSITIONS, CEMENTS, METHODS, AND ARTICLES 审中-公开
    储存稳定的预混合水泥组合物,化学成分,方法和文章

    公开(公告)号:WO2013035083A2

    公开(公告)日:2013-03-14

    申请号:PCT/IB2012/054701

    申请日:2012-09-10

    Abstract: Refrigerated hydraulic cement compositions comprise a mixture of (a) β-tricalcium phosphate powder, (b) monocalcium phosphate comprising monocalcium phosphate anhydrous (MCPA), monocalcium phosphate monohydrate (MCPM), or a combination thereof, wherein a 0.1 g/ml saturated aqueous solution of the monocalcium phosphate has a p H less than 3.0, (c) non-aqueous water-miscible liquid, and (d) an aqueous hydrating liquid. The aqueous hydrating liquid is included in an amount of about 1-50 volume percent, based on the combined volume of the non-aqueous water-miscible liquid and the aqueous hydration liquid, and the refrigerated hydraulic cement composition is storage stable for greater than one day, without setting. Methods of forming hardened cements in vivo and/or for forming implants for use in vivo employ the hydraulic cement compositions.

    Abstract translation: 冷冻水硬性水泥组合物包含(a)磷酸β-磷酸三钙粉末,(b)包含无水磷酸一钙(MCPA),一水合磷酸钙(MCPM)或其组合的一磷酸钙的混合物,其中将0.1g / ml饱和水溶液 磷酸一钙的溶液的ap H小于3.0,(c)非水溶性水溶液,(d)水性保湿液。 基于非水性水混溶性液体和含水水合液体的组合体积,含水水合液体的含量约为1-50体积%,冷冻水硬性水泥组合物储存稳定在一个以上 一天,没有设置。 在体内形成硬化水泥和/或用于形成用于体内的植入物的方法使用水硬性水泥组合物。

    CRYSTALLINE SURGICAL IMPLANT COMPOSITE MATERIALS AND KITS AND METHODS OF MANUFACTURE
    7.
    发明申请
    CRYSTALLINE SURGICAL IMPLANT COMPOSITE MATERIALS AND KITS AND METHODS OF MANUFACTURE 审中-公开
    晶体植入物复合材料及其制造方法及制造方法

    公开(公告)号:WO2009098658A2

    公开(公告)日:2009-08-13

    申请号:PCT/IB2009/050483

    申请日:2009-02-05

    Abstract: A meit-extruded substrate (e.g., fiim, nonwoven web, etc.) that contains a thermoplastic starch formed from a starch and plasticizer is provided. The starch and plasticizer are melt blended together in the presence of a weak organic acid (e.g., lactic acid, formic acid, acetic acid, etc.). By selectively controlling certain parameters of the melt blending process (e.g., extrusion temperature, content of the components, etc.), the present inventors have discovered that the starch may be hydrolyzed in a highly efficient manner to form compositions having a comparably lower weight average molecular weight, polydispersity index, and viscosity, which are particularly suitable for use in the formation of melt-extruded substrates.

    Abstract translation: 提供了包含由淀粉和增塑剂形成的热塑性淀粉的经过挤出的基材(例如,薄膜,非织造纤维网等)。 淀粉和增塑剂在弱有机酸(如乳酸,甲酸,乙酸等)存在下熔融共混。 通过选择性地控制熔融共混过程的某些参数(例如,挤出温度,组分含量等),本发明人已经发现淀粉可以以高效的方式水解以形成具有相对较低重量平均值的组合物 分子量,多分散性指数和粘度,其特别适用于形成熔融挤出的基材。

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