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    PROTECTIVE EFFECT OF DMPC, DMPG, DMPC/DMPG, LYSOPG AND LYSOPC AGAINST DRUGS THAT CAUSE CHANNELOPATHIES
    23.
    发明申请
    PROTECTIVE EFFECT OF DMPC, DMPG, DMPC/DMPG, LYSOPG AND LYSOPC AGAINST DRUGS THAT CAUSE CHANNELOPATHIES 审中-公开
    DMPC，DMPG，DMPC / DMPG，LYSOPG和LYSOPC对药物引起病毒性肝炎的保护作用

    公开(公告)号：WO2018089687A1

    公开(公告)日：2018-05-17

    申请号：PCT/US2017/060936

    申请日：2017-11-09

    Applicant: SIGNPATH PHARMA, INC.

    Inventor： HELSON, Lawrence

    IPC: A61K31/683 ,  A61K31/506

    Abstract: The present invention includes compositions and methods for preventing one or more cardiac channelopathies or conditions resulting from irregularities or alterations in cardiac patterns caused by an active agent or a drug in a human or animal subject comprising: an amount of a lysophosphatidylglycerol adapted for oral administration effective to reduce or prevent one or more cardiac channelopathies or conditions resulting from irregularities or alterations in cardiac patterns caused by the active agent or drug.

    Abstract translation: 本发明包括用于预防由人类或动物受试者中由活性剂或药物引起的心脏模式中的不规则性或改变引起的一种或多种心脏病通道病或病症的组合物和方法，其包含： 的适于口服给药的溶血磷脂酰甘油，其有效减少或预防由活性剂或药物导致的心脏模式的不规则或改变引起的一种或多种心脏通道病或病症。

    ADDITIVE COATED PARTICLES FOR LOW HIGH PERFORMANCE MATERIALS
    25.
    发明申请
    ADDITIVE COATED PARTICLES FOR LOW HIGH PERFORMANCE MATERIALS 审中-公开
    用于低性能材料的添加剂涂层颗粒

    公开(公告)号：WO2018081413A1

    公开(公告)日：2018-05-03

    申请号：PCT/US2017/058512

    申请日：2017-10-26

    Applicant: GARMOR INC.

    Inventor： RESTREPO, David ,  MCINNIS, Matthew ,  STOLTZ, Richard, A. ,  BULLINGTON, Jeff

    IPC: C09C3/04 ,  C09C1/48 ,  C09C3/10

    Abstract: Existing methods of extrusion and other techniques to compound host and additives material uniformly disperse the additive in the host. This innovation uses ball milling to a coat a host particle with an additive dramatically reducing the additive required to achieve a percolative network in the host.

    Abstract translation: 现有的挤出方法和其他技术将复合主体和添加剂材料均匀分散在主体中。 这项创新使用球磨机以添加剂涂覆主体颗粒，大大减少了在主体中实现渗透网络所需的添加剂。

    PHARMACOPERONES OF THE V2 RECEPTOR
    26.
    发明申请
    PHARMACOPERONES OF THE V2 RECEPTOR 审中-公开
    V2受体的药物分子

    公开(公告)号：WO2017066225A1

    公开(公告)日：2017-04-20

    申请号：PCT/US2016/056502

    申请日：2016-10-12

    Applicant: TEXAS TECH UNIVERSITY SYSTEM

    Inventor： CONN, P., Michael

    IPC: A61K31/428 ,  A61K31/166 ,  A61K31/13 ,  G01N33/53 ,  G01N33/567 ,  A61P43/00

    CPC classification number: A61K31/13 ,  A61K31/166 ,  A61K31/428 ,  G01N33/5035 ,  G01N2333/726

    Abstract: The present invention includes compositions and methods for treating a subject with a G protein coupled receptors (GPCRs) misfolded, misrouted, or both misfolded and misrouted protein comprising: obtaining a sample from the subject suspected of having a G protein coupled receptor (GPCR) that is misfolded, misrouted, or both misfolded and misrouted; and providing the subject with an effective amount of a pharmacoperone that prevents misfolding, misrouting, or both misfolding and misrouting of the GPCR protein.

    Abstract translation: 本发明包括用于治疗患有G蛋白偶联受体（GPCR）错误折叠，错误路由或同时错误折叠和错误路由蛋白的受试者的组合物和方法，包括：从怀疑具有 G蛋白偶联受体（GPCR）错误折叠，错误路由或错误折叠和错误路由; 并向受试者提供有效量的药物辅料，以防止GPCR蛋白质的错误折叠，误传或错误折叠和误传。

    USE OF PROTEINS TO CONTROL MOLLUSCS
    27.
    发明申请
    USE OF PROTEINS TO CONTROL MOLLUSCS 审中-公开
    使用蛋白质来控制麦芽汁

    公开(公告)号：WO2016191430A1

    公开(公告)日：2016-12-01

    申请号：PCT/US2016/033945

    申请日：2016-05-24

    Applicant: MARRONE BIO INNOVATIONS, INC.

    Inventor： BOSTON, Matt

    IPC: A01N63/02 ,  A01N25/02 ,  C02F1/50

    CPC classification number: A01N63/02 ,  A01N37/46 ,  C02F1/50 ,  C02F3/327 ,  C02F2103/007 ,  Y02W10/18

    Abstract: The present disclosure includes proteins toxic to Zebra mussels, its method of production, and uses thereof. The protein was isolated from whole cell broth of Pseudomonas protegens CL145A via anion exchange chromatographic fractionation. The protein was found to be a secondary metabolite with highest expression at the fermentative production harvest stage.

    Abstract translation: 本公开内容包括对斑马贻贝有毒的蛋白质，其生产方法及其用途。 通过阴离子交换色谱分离法从蛋白质假单胞菌CL145A的全细胞培养液中分离出蛋白质。 发现蛋白质是发酵生产收获阶段表达最高的次生代谢产物。

    APPARATUS AND COMPUTERIZED METHOD FOR PREDICTING ASPHALTENE PRECIPITATION BASED ON AGGREGATION THERMODYNAMICS
    28.
    发明申请
    APPARATUS AND COMPUTERIZED METHOD FOR PREDICTING ASPHALTENE PRECIPITATION BASED ON AGGREGATION THERMODYNAMICS 审中-公开
    基于聚集热力学预测沥青沉降的装置和计算方法

    公开(公告)号：WO2016176313A1

    公开(公告)日：2016-11-03

    申请号：PCT/US2016/029539

    申请日：2016-04-27

    Applicant: TEXAS TECH UNIVERSITY SYSTEM

    Inventor： CHEN, Chau-Chyun ,  HAO, Yifan ,  WANG, Meng ,  ISLAM, Md Rashedul

    IPC: G01N33/24 ,  G06Q50/02 ,  E21B47/00 ,  C09K8/00 ,  G06F19/00

    CPC classification number: G01N33/2823 ,  C09K8/524 ,  E21B37/06 ,  G06F19/704

    Abstract: The present invention includes a method for thermodynamic modeling of asphaltene precipitation comprising: calculating the Gibbs free energy for the transition between asphaltene molecules in solution into an imaginary crystalline asphaltene nanoaggregates or asphaltene nanocrystals; calculating the Gibbs free energy for the transition between asphaltene nanoaggregates or nanocrystals redissolving into colloidal asphaltene nanoaggregates using the computer: and predicting asphaltene solubility in a solvent, wherein the predicted asphaltene solubility is used to add a solvent to a liquid, semi-solid, or solid comprising aspahaltenes to prevent, e.g., fouling of a wellbore, pipeline, downstream unit operations, to provide flow assurance for crude oil pipeline network, or for petroleum crude blending.

    Abstract translation: 本发明包括沥青质沉淀的热力学模拟方法，包括：计算溶液中沥青质分子在假想结晶沥青质纳米聚集体或沥青质纳米晶体中的转变的吉布斯自由能; 计算沥青质纳米聚集体或使用计算机再溶解成胶体沥青质纳米聚集体的纳米晶体之间的转变的吉布斯自由能，并预测沥青质在溶剂中的溶解度，其中预测的沥青质溶解度用于将溶剂添加到液体，半固体或 固体包含天竺葵素，以防止例如井筒，管道，下游单元操作的结垢，为原油管网提供流动保证，或用于石油原油混合。

    THERMAL SPRAY OF REPAIR AND PROTECTIVE COATINGS
    29.
    发明申请
    THERMAL SPRAY OF REPAIR AND PROTECTIVE COATINGS 审中-公开
    热喷涂修复和保护涂层

    公开(公告)号：WO2016160400A1

    公开(公告)日：2016-10-06

    申请号：PCT/US2016/023435

    申请日：2016-03-21

    Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.

    Inventor： SEAL, Sudipta ,  WARD, David ,  SARAF, Shashank ,  GUPTA, Ankur

    IPC: C23C4/04 ,  C23C4/12 ,  C23C4/10

    CPC classification number: C23C4/067 ,  C23C4/04 ,  C23C4/08 ,  C23C4/10 ,  C23C4/11 ,  C23C4/12 ,  C23C4/134 ,  C23C4/16 ,  C23C4/18 ,  C23C28/345

    Abstract: This invention provides a method for graphene or graphene oxide reinforcement in a metallic thermal spray coating. The incredible properties of graphene and graphene oxide make them attractive options to increase the mechanical properties in a variety of materials. Recent developments in the manufacturing of graphene oxide and reduced graphene oxide powders have greatly reduced their cost, making them viable additives in thermal spray powders for widespread use in industry.

    Abstract translation: 本发明提供了一种在金属热喷涂中的石墨烯或氧化石墨烯增强方法。 石墨烯和氧化石墨烯的令人难以置信的性质使它们成为增加各种材料的机械性能的有吸引力的选择。 石墨烯氧化物和还原型石墨烯氧化物粉末的制造最近的发展大大降低了它们的成本，使得它们在工业中广泛使用的热喷涂粉末中是可行的添加剂。

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