公开(公告)号：WO2016198900A3

公开(公告)日：2017-01-19

申请号：PCT/GB2016051746

申请日：2016-06-10

Applicant: IMP INNOVATIONS LTD

Inventor： EDEL JOSHUA BENNO ,  FREEDMAN KEVIN JOSEPH

IPC: G01N15/10 ,  G01N15/00 ,  G01N33/487

CPC classification number: G01N15/1031 ,  G01N15/1056 ,  G01N33/48721 ,  G01N2015/0038

Abstract: The disclosure relates to an apparatus and associated method for concentration of polarizable molecules within a fluid medium. The apparatus comprising a structure defining a cavity, having a cross-sectional dimension of 200 nm or less; at least two translocation electrodes positioned relative to the structure to enable generation of a DC electric field passing through the cavity; and at least two trapping electrodes positioned relative to the structure to enable generation of a time-varying electric field proximal to the cavity inlet.

Abstract translation: 本公开涉及用于在流体介质内浓缩可极化分子的装置和相关方法。 该装置包括限定空腔的结构，其横截面尺寸为200nm或更小; 至少两个位移电极相对于该结构定位，以便能够产生通过腔的DC电场; 以及相对于该结构定位的至少两个俘获电极，以使得能够产生靠近腔入口的时变电场。

公开(公告)号：WO2015169931A9

公开(公告)日：2016-01-21

申请号：PCT/EP2015060128

申请日：2015-05-07

Applicant: IMP INNOVATIONS LTD

Inventor： KOVAC MIRKO ,  ALHINAI TALIB MUHAMMAD TALIB

IPC: B64C39/02

CPC classification number: B64C39/024 ,  B64C25/00 ,  B64C39/02 ,  B64C2201/027 ,  B64C2201/042 ,  B64C2201/066 ,  B64C2201/08 ,  B64C2201/108 ,  B64C2201/12 ,  B64C2201/146 ,  B64C2201/18 ,  B64D2211/00 ,  G05D1/104

Abstract: There is provided a method of using a device capable of controlled flight in a surrounding environment, the device comprising: lifting means for providing lift to the device; object-retaining means for holding an object to be affixed to a target site; and a dispensing assembly for dispensing an adhesive, wherein the method comprises: controlling the lifting means so as to controllably fly the device in the surrounding environment; and using the device to affix an object held by the object-retaining means to a target site in the surrounding environment by dispensing an adhesive from the dispensing assembly. Thus, an aerial device, for example a robotic device, may be used to fly to a desired location and affix an object at the desired location, by dispensing, ejecting or otherwise applying an adhesive.

Abstract translation: 提供了一种使用能够在周围环境中控制飞行的装置的方法，该装置包括：提升装置，用于向装置提供电梯; 用于保持待贴在目标地点上的物体的物体保持装置; 以及用于分配粘合剂的分配组件，其中所述方法包括：控制所述提升装置，以便在所述周围环境中可控地飞行所述装置; 并且使用该装置通过从分配组件分配粘合剂来将由对象保持装置保持的对象附加到周围环境中的目标位置。 因此，例如机器人装置的空中装置可以用于飞行到期望的位置，并通过分配，喷射或以其它方式施加粘合剂将物体附着在所需位置。

公开(公告)号：WO2015159097A3

公开(公告)日：2015-12-30

申请号：PCT/GB2015051163

申请日：2015-04-17

Applicant: IMP INNOVATIONS LTD

Inventor： KALISZCZAK MACIEJ ADAM ,  ABOAGYE ERIC OFORI

IPC: G01N33/50

CPC classification number: G01N33/5008 ,  G01N2800/52

Abstract: The invention provides a method for identifying a subject with a disease or condition characterised by the presence of unwanted cells as being likely to respond to treatment comprising administration of a KDAC6 inhibitor having the structure of Formula (I), wherein said method comprises determining whether the subject's unwanted cells have or are likely to have an increased dependency on autophagy for survival, and wherein Formula (I) comprises: (Formula (I)).

Abstract translation: 本发明提供用于鉴定具有疾病或病症特征的受试者的方法，其特征在于存在可能对治疗有反应的不希望的细胞，包括施用具有式（I）结构的KDAC6抑制剂，其中所述方法包括确定是否 受试者的不想要的细胞具有或可能对生存的自噬增加依赖性，并且其中式（I）包含：（式（I））。

公开(公告)号：WO2015159082A3

公开(公告)日：2015-12-10

申请号：PCT/GB2015051148

申请日：2015-04-15

Applicant: IMP INNOVATIONS LTD

Inventor： RISTIC MIHAILO ,  MCGINLEY JOHN VINCENT MARIO ,  YOUNG IAN ROBERT

IPC: G01R33/38 ,  G01R33/383 ,  G01R33/3873 ,  G01R33/3875 ,  G01R33/44

CPC classification number: G01R33/56563 ,  G01R33/3802 ,  G01R33/3806 ,  G01R33/383 ,  G01R33/3873 ,  G01R33/3875 ,  G01R33/445

Abstract: The invention relates to an MRI apparatus and a method of MRI involving the acquisition of a first and a second MRI image with mutually different orientations between the BO magnetic field and the object to be investigated. For instance, when imaging structures such as a tendon, due to the magic angle effect, this results in a change in image contrast. According to the invention, a coregistration can be performed between the first and the second MRI image. Moreover, the orientation of a structure within the object can be determined on the basis of the different orientations and the image intensity in the first and the second MRI image. The invention further discloses an apparatus for carrying out the method and a method of shimming the BO magnetic field of the apparatus.

Abstract translation: 本发明涉及MRI装置和MRI的方法，涉及在BO磁场和待研究对象之间具有相互不同取向的第一和第二MRI图像的获取。 例如，当成像结构如腱由于魔角效应而导致图像对比度的变化。 根据本发明，可以在第一和第二MRI图像之间执行核心标准。 此外，可以基于第一和第二MRI图像中的不同取向和图像强度来确定对象内的结构的取向。 本发明还公开了一种用于实施该装置的BO磁场的方法和方法的装置。

公开(公告)号：WO2015136299A3

公开(公告)日：2015-11-26

申请号：PCT/GB2015050737

申请日：2015-03-13

Applicant: IMP INNOVATIONS LTD ,  IMPRESSION TECHNOLOGIES LTD

Inventor： ADAM GEORGE ,  BALINT DANIEL ,  DEAN TREVOR ,  DEAR JOHN ,  EL FAKIR OMER ,  FOSTER ALISTAIR ,  LIN JIANGUO ,  WANG LILIANG

IPC: C22F1/04 ,  C22F1/047 ,  C22F1/05

CPC classification number: C22F1/047 ,  C22F1/04 ,  C22F1/05

Abstract: A method of forming a part from sheet metal alloy is provided, for example, forming a part from aluminium alloy. The method comprises heating (A) the sheet metal alloy to a temperature at which solution heat treatment of the alloy occurs and so as to achieve solution heat treatment. The sheet is cooled (B) at least the critical cooling rate for the alloy and then placed between dies to form (C) it into or towards the part.

Abstract translation: 例如，提供从铝合金形成部分的从金属板合金形成部件的方法。 该方法包括将（A）金属合金加热到合金的固溶热处理的温度，并进行固溶热处理。 片材至少冷却（B）合金的临界冷却速度，然后放置在模具之间以形成（C）到或朝向部件。

公开(公告)号：WO2014191771A3

公开(公告)日：2015-01-22

申请号：PCT/GB2014051671

申请日：2014-05-30

Applicant: IMP INNOVATIONS LTD ,  ORIGUEN JOSE ANTONIO ,  DRAGOTTI PIER LUIGI ,  BLU THIERRY ALBERT JEAN-LOUIS ,  UNIV HONG KONG CHINESE

Inventor： ORIGUEN JOSE ANTONIO ,  DRAGOTTI PIER LUIGI ,  BLU THIERRY ALBERT JEAN-LOUIS

IPC: G06T5/00 ,  G06F17/14 ,  G06T3/40 ,  G06T5/50

CPC classification number: H04B1/16 ,  G06F5/01 ,  G06F17/14 ,  G06F2205/00 ,  G06K9/4604 ,  G06T3/4053 ,  G06T3/4084 ,  G06T5/001 ,  G06T5/50 ,  G06T7/13 ,  G06T2207/20048 ,  G06T2207/20212

Abstract: A signal processing method for estimating a frequency domain representation of signal from a series of samples distorted by an instrument function, the method comprising obtaining the series of samples; obtaining a set of coefficients that fit a set of basis functions to a complex exponential function wherein the set of basis functions comprises a plurality of basis functions each defined by a shifted version of the instrument function in a signal domain; estimating the frequency domain representation of the signal based on the series of samples and the coefficients. This is wherein the estimate of the instrument function is based on a characterisation of the instrument function in the frequency domain at frequencies associated with the complex exponential function.

Abstract translation: 一种用于估计来自由仪器功能失真的一系列样本的信号的频域表示的信号处理方法，所述方法包括获得所述一系列样本; 获得一组适合一组基函数的系数到复指数函数，其中所述一组基函数包括由信号域中的仪器函数的移位版本定义的多个基函数; 基于一系列样本和系数估计信号的频域表示。 这是其中仪器功能的估计是基于频率域中与复指数函数相关联的频率的仪器功能的表征。

公开(公告)号：WO2013175239A3

公开(公告)日：2014-02-27

申请号：PCT/GB2013051389

申请日：2013-05-24

Applicant: IMP INNOVATIONS LTD

Inventor： KINGSBURY BENJAMIN FRANCIS KNATCHBULL ,  WU ZHENTAO ,  LI KANG

IPC: F01N3/28

CPC classification number: B01J35/04 ,  B01D53/9454 ,  B01J21/04 ,  B01J23/10 ,  B01J37/08 ,  B32B1/08 ,  B32B3/12 ,  B32B18/00 ,  B32B2262/105 ,  B32B2605/08 ,  F01N3/2828 ,  F01N2330/36 ,  Y10T29/49345 ,  Y10T428/24149

Abstract: A catalytic converter substrate comprising a plurality of micro-structured hollow ceramic tubes (20), each tube having an inside surface (30) and an outside surface (40), the inside surface having openings to micro-channels (55) distributed radially throughout the tube cross-section, said micro-channels extending from said openings in the inside surface towards the outside surface.

Abstract translation: 一种催化转化器基板，包括多个微结构的中空陶瓷管（20），每个管具有内表面（30）和外表面（40），所述内表面具有径向分布的微通道（55）的开口 管横截面，所述微通道从内表面中的所述开口延伸到外表面。

公开(公告)号：WO2013186552A2

公开(公告)日：2013-12-19

申请号：PCT/GB2013051534

申请日：2013-06-11

Applicant: IMP INNOVATIONS LTD

Inventor： BACHIR ABDELMALIK ,  LEUNG KIN

IPC: H04W24/00 ,  H04W60/00 ,  H04W64/00

CPC classification number: H04W64/00 ,  H04W4/028

Abstract: A system for collecting and characterising mobility data of a plurality of mobile wireless communications devices is disclosed, the system comprising: at least a first and a second detector having a respective first and second detection range and each arranged to detect entry and departure of a mobile wireless communications device into the detection range and store associated mobility data; and an aggregator arranged to aggregate mobility data received from the detectors.

Abstract translation: 公开了一种用于收集和表征多个移动无线通信设备的移动性数据的系统，该系统包括：至少第一和第二检测器，其具有相应的第一和第二检测范围，并且每个检测器被布置成检测移动 无线通信设备进入检测范围并存储相关移动数据; 以及聚合器，其被布置成聚集从所述检测器接收的移动性数据。

公开(公告)号：WO2012146891A3

公开(公告)日：2013-10-10

申请号：PCT/GB2012000381

申请日：2012-04-25

Applicant: IMP INNOVATIONS LTD ,  PLANT DANIEL ,  OFFER GREGORY ,  SILVERSIDES RICHARD WILLIAM

Inventor： PLANT DANIEL ,  OFFER GREGORY ,  SILVERSIDES RICHARD WILLIAM

IPC: B60L11/04 ,  B60K6/46 ,  B60L11/12 ,  B60L11/14 ,  B60W10/06 ,  H02J7/14

CPC classification number: B60W30/182 ,  B60L11/12 ,  B60L11/123 ,  B60L11/14 ,  B60L2240/42 ,  B60L2240/44 ,  B60L2240/622 ,  B60L2250/26 ,  B60W10/06 ,  B60W10/08 ,  B60W20/15 ,  B60W2510/244 ,  H02J7/1415 ,  Y02T10/6217 ,  Y02T10/6286 ,  Y02T10/642 ,  Y02T10/7022 ,  Y02T10/7077 ,  Y02T10/7258 ,  Y02T10/7291 ,  Y02T90/16 ,  Y02T90/162

Abstract: A method of operating a drive train (110) for a hybrid electric vehicle, and a drive train, is disclosed. The drive train comprises an internal combustion engine (120), a first electrical machine (130) and electrical energy storage means (150). The internal combustion engine is coupled to drive the first electrical machine as a generator and the first electrical machine connected to supply electrical energy to the electrical energy storage means. The electrical energy storage means is arranged for supplying electrical energy to at least a second electrical machine (170) for driving wheels (180) of a hybrid electric vehicle. The method comprises the steps of sensing a parameter indicative of the voltage across the electrical energy storage means and, in response to this sensed parameter, controlling the internal combustion engine and/or the first electrical machine such that the first electrical machine operates to give rise to a voltage output of the first electrical machine such that the electrical energy storage means is charged without the need for power electronics.

Abstract translation: 公开了一种操作用于混合动力电动车辆的传动系（110）和传动系的方法。 传动系包括内燃机（120），第一电机（130）和电能存储装置（150）。 所述内燃机被联接以驱动所述第一电机作为发电机，并且所述第一电机被连接以向所述电能存储装置提供电能。 电能存储装置被布置成用于向至少第二电机（170）提供电能，用于驱动混合动力电动车辆的车轮（180）。 该方法包括以下步骤：感测指示电能存储装置两端的电压的参数，并且响应于该感测参数，控制内燃机和/或第一电机使得第一电机运行以产生 到第一电机的电压输出，使得电能存储装置在不需要电力电子装置的情况下被充电。

公开(公告)号：WO2013104918A3

公开(公告)日：2013-08-29

申请号：PCT/GB2013050054

申请日：2013-01-11

Applicant: IMP INNOVATIONS LTD ,  HASKARD DORIAN ,  CHANG SHANG-HUNG ,  JOHNS MICHAEL

Inventor： HASKARD DORIAN ,  CHANG SHANG-HUNG ,  JOHNS MICHAEL

IPC: C07K16/18

CPC classification number: C07K16/18 ,  C07K2317/565 ,  C07K2317/622

Abstract: The present invention relates to an isolated specific binding member, such as an antibody or fragment thereof, which is capable of binding an antigen on oxidised low density lipoprotein (ox LDL). The antigen is capable of being bound by a member comprising one or more binding domains selected from domains comprising an amino acid sequence substantially as set out as GYAFTNYL, INPGSGGT and ARSFKWKFDY.

Abstract translation: 本发明涉及能够在氧化的低密度脂蛋白（oxLDL）上结合抗原的分离的特异性结合成员，例如抗体或其片段。 抗原能够被包含一个或多个选自包含基本上如GYAFTNYL，INPGSGGT和ARSFKWKFDY的氨基酸序列的结构域的结构域的成员结合。