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    DEVICE FOR MAGNETIC PROFILING OF PARTICLES IN A FLOW
    41.
    发明申请
    DEVICE FOR MAGNETIC PROFILING OF PARTICLES IN A FLOW 审中-公开
    用于在流动中磁性分布颗粒的装置

    公开(公告)号：WO2017054075A1

    公开(公告)日：2017-04-06

    申请号：PCT/CA2016/051128

    申请日：2016-09-27

    申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

    发明人： KELLEY, Shana ,  SARGENT, Edward ,  POUDINEH, Mahla ,  MOHAMADI, Reza ,  ALDRIDGE, Peter

    IPC分类号： G01N15/00

    CPC分类号： G01N15/1484 ,  B01L3/502746 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/086 ,  B03C1/0332 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/18 ,  B03C2201/26 ,  G01N15/1475 ,  G01N2015/1006 ,  G01N2015/149

    摘要： Methods and devices for magnetic profiling of target particles in a flow. There are a plurality of flow rate-reducing structures in a flow chamber. Each flow rate-reducing structure is provided with a localized magnetic attractive force, the magnetic attractive force defining a capture zone in the vicinity of the flow rate-reducing structure. The size of capture zones may be variable for different locations within the device. The magnetic attractive force, in the capture zone, is sufficiently high to overcome the drag force on a given subset of the target particles to promote capture of any particles belonging to the subset of the target particles in the capture zone. Different target particles having different magnetic susceptibility are captured in different capture zones.

    摘要翻译： 流动中目标颗粒磁性分析的方法和装置。 在流动室中存在多个减少流量的结构。 每个减流结构都具有局部的磁力吸引力，磁力吸引力限定了减流结构附近的捕获区。 对于设备内的不同位置，捕获区域的大小可能是可变的。 在捕获区域中的磁性吸引力足够高以克服目标颗粒的给定子集上的阻力，以促进捕获属于捕获区域中目标颗粒子集的任何颗粒。 在不同的捕获区域捕获具有不同磁化率的不同目标颗粒。

    OXADIAZOLE CYCLIC PEPTIDES
    42.
    发明申请
    OXADIAZOLE CYCLIC PEPTIDES 审中-公开
    奥沙利环循环肽

    公开(公告)号：WO2017045063A1

    公开(公告)日：2017-03-23

    申请号：PCT/CA2016/000234

    申请日：2016-09-16

    申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

    发明人： YUDIN, Andrei ,  FROST, John, R.

    IPC分类号： C07K5/10 ,  C07D498/08 ,  C07K1/00 ,  C07K5/00

    CPC分类号： C07D498/18 ,  C07K1/02 ,  C07K7/06

    摘要： The present invention relates to cyclic amino acid molecules, in particular 1,3,4-oxadiazole containing macrocyclic peptides, and a process to produce the same. The process involves the macrocyclization of amino acids or linear peptides. Specifically, the process comprises reacting an amino acid molecule with an isocyano-iminophosphorane and an aldehyde or a ketone.

    摘要翻译： 本发明涉及环状氨基酸分子，特别是含有大环肽的1,3,4-恶二唑，以及其制备方法。 该方法涉及氨基酸或线性肽的大环化。 具体地，该方法包括使氨基酸分子与异氰酰亚氨基磷烷和醛或酮反应。

    SYSTEMS AND METHODS FOR REDUCING SWITCH STRESS IN SWITCHED MODE POWER SUPPLIES
    43.
    发明申请
    SYSTEMS AND METHODS FOR REDUCING SWITCH STRESS IN SWITCHED MODE POWER SUPPLIES 审中-公开
    用于降低开关电源开关应力的系统和方法

    公开(公告)号：WO2017008140A1

    公开(公告)日：2017-01-19

    申请号：PCT/CA2016/000191

    申请日：2016-07-11

    申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO ,  MAXIM INTEGRATED PRODUCTS, INC.

    发明人： VUKADINOVIC, Nenad ,  PRODIC, Aleksandar ,  ARNOLD, Cory Brent ,  MIWA, Brett A. ,  BAKER, Michael Warren

    IPC分类号： H02M1/00

    CPC分类号： H02M1/088 ,  H02M1/14 ,  H02M3/158 ,  H02M2001/0058 ,  Y02B70/1491

    摘要： In various embodiments described in the present disclosure, various methods and systems are introduced, that may reduce and/or eliminate the voltage spikes on the power switches by avoiding operation at zero-ripple duty ratios. In a first aspect, a method for reducing voltage spikes across switches in a multi-level converter is provided, the method comprising: receiving an error value associated with a difference between a measured output voltage and a reference output voltage; determining a target duty cycle value based at least on a control feedback loop adapted to minimize the error value; if the target duty cycle value is equal or approximately equal to one or more critical duty ratio values, controlling the operation of the multi-level converter to operate the multi-level converter with an averaging sequence, the averaging sequence adapted to, on average, result in, or sufficiently approximate, the one or more critical duty ratio values, but not operate at the one or more critical duty ratio values; and generating one or more pulse-width modulated signals to control the operation of the multi-level converter based on at least one of the target duty cycle and the averaging sequence.

    摘要翻译： 在本公开描述的各种实施例中，引入了各种方法和系统，其可以通过避免在零波纹占空比下的操作来减少和/或消除功率开关上的电压尖峰。 在第一方面，提供了一种用于降低多电平转换器中的开关的电压尖峰的方法，所述方法包括：接收与所测量的输出电压和参考输出电压之间的差值相关联的误差值; 至少基于适于最小化所述误差值的控制反馈回路来确定目标占空比值; 如果目标占空比值等于或近似等于一个或多个关键占空比值，则控制多电平转换器的操作以平均序列来操作多电平转换器，平均序列适于平均地， 导致或充分接近一个或多个关键占空比值，但不在一个或多个关键占空比值下运行; 以及产生一个或多个脉冲宽度调制信号，以基于目标占空比和平均序列中的至少一个来控​​制多电平转换器的操作。

    TRANSPARENT METALLO-DIELECTRIC COATINGS, STRUCTURES, AND DEVICES, AND METHODS OF FABRICATION THEREOF
    44.
    发明申请
    TRANSPARENT METALLO-DIELECTRIC COATINGS, STRUCTURES, AND DEVICES, AND METHODS OF FABRICATION THEREOF 审中-公开
    透明金属介电涂层，结构和器件及其制造方法

    公开(公告)号：WO2016183691A1

    公开(公告)日：2016-11-24

    申请号：PCT/CA2016/050578

    申请日：2016-05-20

    申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

    发明人： KHERANI, Nazir Pyarali ,  MAHTANI, Pratish ,  KHALATPOUR, Ali ,  KO, Remy Howard Haoching ,  CLARK, John Kenji ,  FORMICHEV, Stepan Olegovich ,  DANESHVAR, Hoofar

    IPC分类号： B32B15/04 ,  B32B33/00 ,  B32B37/14 ,  B82Y20/00 ,  E06B7/00 ,  G02B1/10 ,  G02B5/28 ,  H01B1/22 ,  H01B5/14 ,  H01L33/42 ,  G02B5/08 ,  H01L31/0224

    CPC分类号： A47C7/62 ,  A45C13/001

    摘要： Various embodiments of the present disclosure provide metallo- dielectric low-emissivity coatings, structures coated with such low-emissivity coatings, and methods of fabrication thereof. The metallo-dielectric coatings are formed from a visibly-transparent, and heat-reflective, multi-layer structure including an transparent amorphous substrate having a nano-thin metal layer adhered thereto, wherein the nano-thin metal layer is adhered to a transparent amorphous substrate via a transparent dielectric seeding layer. The transparent amorphous dielectric layer may include amorphous carbon. Various example embodiments are disclosed in which such coatings are employed as passive or active devices, such as transparent heat mirrors, transparent resistive heaters for windows and windshields, transparent electromagnetically isolating security films, near invisible radio transceivers and transmitters.

    摘要翻译： 本公开的各种实施例提供金属介电低发射率涂层，涂覆有这种低发射率涂层的结构及其制造方法。 该金属介电涂层由具有透明和热反射的多层结构形成，该多层结构包括具有粘附到其上的纳米薄金属层的透明非晶衬底，其中纳米薄金属层粘附到透明无定形 衬底经由透明电介质接种层。 透明无定形介电层可以包括无定形碳。 公开了各种示例性实施例，其中这种涂层被用作无源或有源器件，例如透明加热镜，用于窗户和挡风玻璃的透明电阻加热器，透明电磁隔离安全膜，靠近不可见的无线电收发器和发射器。

    FLYBACK CONVERTER
    45.
    发明申请
    FLYBACK CONVERTER 审中-公开
    FLYBACK转换器

    公开(公告)号：WO2016101058A1

    公开(公告)日：2016-06-30

    申请号：PCT/CA2015/000587

    申请日：2015-11-30

    申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

    发明人： AHSANUZZAMAN, S. M. ,  MAHDAVIKHAH, Behzad ,  RADIC, Aleksandar ,  PRODIC, Aleksandar

    IPC分类号： H02M1/08 ,  H02M3/06 ,  H02M3/155 ,  H02M5/08 ,  H02M7/217

    CPC分类号： H02M3/33523 ,  H02M1/4258 ,  H02M2001/0009 ,  H02M2001/0074 ,  Y02B70/126

    摘要： The flyback converter generally has a capacitive divider operatively connectable to a voltage source for receiving an input voltage, the capacitive divider having a plurality of capacitive devices connected in series from one another; a transformer having a plurality of primary windings inductively coupled to at least one secondary winding, each one of the primary windings of the transformer being connected in parallel to a corresponding one of the capacitive devices of the capacitive divider via a switching device, each of the at least one secondary winding being connected to a forwardly biased and capacitive circuit connectable to an output load; and a controller connected to each one of the switching devices for operating the flyback converter to power the output load with the voltage source.

    摘要翻译： 反激转换器通常具有可操作地连接到用于接收输入电压的电压源的电容分压器，该电容分压器具有彼此串联连接的多个电容器件; 变压器，其具有感应耦合到至少一个次级绕组的多个初级绕组，变压器的每个初级绕组经由开关装置并联连接到电容分压器的相应的一个电容性装置， 至少一个次级绕组连接到可连接到输出负载的向前偏置和电容电路; 以及连接到每个开关装置的控制器，用于操作所述反激转换器以用所述电压源为所述输出负载供电。