摘要:
Es wird eine Platte (10) für die Dünnschichtchromatographie mit einer Trägerplatte (12), mindestens einer länglichen Vertiefung mit einem Trennmittel (16) und einer Abdeckfolie (18) für die mindestens eine längliche Vertiefung angegeben, die eine Zwischenfolie (20) aufweist, die zwischen der Trägerplatte (12) und der Abdeckfolie (18) angeordnet ist und die mindestens eine längliche Ausnehmung (14) umfasst, um die längliche Vertiefung zu bilden, wobei die Abdeckfolie (18) mindestens eine Ausnehmung (22, 24, 26) zum Aufbringen eines Laufmittels und einer Probe auf das Trennmittel (16) aufweist. Dabei ist der mindestens einen länglichen Ausnehmung (14) ein Reservoir (28) für das Laufmittel zugeordnet. Die Platte (10) eignet sich besonders für den automatisierten Betrieb.
摘要:
A thin layer chromatograph device comprises a thin layer chromatograph plate, a plate carrier and a housing, such that the plate is protected during storage and use in the field. A sample may be spotted on the plate without exposing the plate to contamination by handling the plate by field personnel. For example, an aperture is provided for introducing a sample onto the a thin layer chromatographic surface without removing the plate during spotting, development, and observation of the Rf caused by elution of the sample by a mobile phase.
摘要:
A device utilizing agglutination and its method of use to diagnose diseases or conditions. The diagnostic device may comprise a substrate having pores, an agglutination zone, and a test readout zone wherein said agglutination zone is functionalized with an agglutinating agent to cause agglutination of the sample.
摘要:
A three-dimensional chromatographic detection method providing the detection of components inside a tree-dimensional separation body (1) or at a boundary surface (10) by the time the components emerge from the body.
摘要:
A method and device for performing chromatography includes placing a monolithic polymer layer in contact with a liquid mobile phase. The monolithic polymer layer may be neutral, positively charged, or negatively charged. A first electrode and second electrode are coupled to the monolithic polymer layer. An electrical potential is created between the first electrode and the second electrode. In some embodiments, the monolithic polymer layer may be placed in a sealed chamber, which may have a pressure greater than atmospheric pressure. Additionally, in some embodiments, the mobile phase is advanced through the monolithic polymer layer via one of a number of forced flow techniques.
摘要:
The present invention describes a system and method for separation of proteins, peptides and glycans by one-dimensional or two-dimensional electroosmosis-driven planar chromatography. Separation is performed using amphiphilic polymeric membranes, amphiphilic thin-layer chromatography plates or other planar amphiphilic surfaces as the stationary phase with a combination of organic and/or aqueous buffers as the mobile phase. Systematic selection of stationary phase supports, mobile phase buffers and operating conditions allow for the adaptation of the invention to a broad range of applications in proteomics, mass spectrometry, drug discovery and the pharmaceutical sciences.
摘要:
Microfluidic devices (7) that form layered structures provide a liquid handling interface with external devices as well as reduce consumption of sample and buffer in analytical operations. These microfluidic devices (7) are suitable for operations designed for lab-on-a-chip functions. The microfluidic devices (7) accomplish sample injection in a single channel (6) without intersecting channels on the same plane. These devices (7) may be formed through injection-molding fabrication methods.