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    ARTIFICIAL INTERVERTEBRAL DISC
    71.
    发明申请
    ARTIFICIAL INTERVERTEBRAL DISC 审中-公开
    人造椎间盘

    公开(公告)号：WO2004049980A1

    公开(公告)日：2004-06-17

    申请号：PCT/NL2003/000842

    申请日：2003-11-28

    Applicant: DSM IP ASSETS B.V. ,  MARISSEN, Roelof

    Inventor： MARISSEN, Roelof

    IPC: A61F2/44

    CPC classification number: A61F2/442 ,  A61F2/30965 ,  A61F2002/30009 ,  A61F2002/30909 ,  A61F2002/4495 ,  A61F2250/0028

    Abstract: Artificial intervertebral disc, comprising a nucleus of flexible material with the shape of a flattened body, with a lower and an upper side connected by a lateral surface, having a rounded-preferably circular or ellipsoid-shape, around which at least substantially radially oriented windings of a traction-resistant fibre have been applied. The fibres have a tensile strength of at least 1 GPa and a modulus of at least 10 GPa.

    Abstract translation: 人造椎间盘，其包括具有扁平体形状的柔性材料的细胞核，其下部和上侧通过侧表面连接，具有圆形优选为圆形或椭圆形形状，至少基本上径向定向的绕组 的耐磨纤维已被应用。 纤维的拉伸强度至少为1GPa，模量为至少10GPa。

    PROSTHETIC ANTERIOR CRUCIATE LIGAMENT DESIGN
    76.
    发明申请
    PROSTHETIC ANTERIOR CRUCIATE LIGAMENT DESIGN 审中-公开
    人工前房腱索设计

    公开(公告)号：WO1991007929A2

    公开(公告)日：1991-06-13

    申请号：PCT/US1990006894

    申请日：1990-11-26

    Applicant: BAXTER INTERNATIONAL INC.

    Inventor： BAXTER INTERNATIONAL INC. ,  FRONK, David, M. ,  BROOKSTEIN, David, S. ,  SKELTON, John

    IPC: A61F02/08

    CPC classification number: A61F2/0811 ,  A61F2/08 ,  A61F2002/0852 ,  A61F2002/0858 ,  A61F2002/087 ,  A61F2002/0882 ,  A61F2250/0028

    Abstract: An artificial ligament device (36) is provided for joining the ends of two bones (12, 14) wherein at least one of the bones has a tunnel (32) extending therethrough. The device comprises a multilayered or tubular woven ligament (35) having an intra-articular region (38), at least one bend region (40), and at least one end region (46), each region being woven so as to possess qualities of flexibility and strength suitable to the particular types of stresses it receives during use. The end region and a portion of the bend region are encased within a polymer bone block (8); usually by thermomolding, and the bone block is inserted into the bone tunnel to attach the ligament. The bone block is molded to provide a fixed bend radius (60) for the ligament at the point of exit therefrom so as to control the amount of bending stress on the ligament during flexure and extension of the joint.

    Abstract translation: 人造韧带装置（36）连接两个骨（12,14）的端部，其中一个骨具有内部通道（32）。 该装置包括设置有关节内区域（38），至少一个弯曲区域（40）和至少一个端部区域（46）的多层或管状编织韧带（35），每个区域被编织 以便具有适合于其在使用过程中必须经受的约束类型的灵活性和抵抗性质量。 通常通过热成型将末端区域和弯曲区域的一部分封闭在聚合物骨块（8）中，并且将该块引入骨头的隧道中以固定韧带。 骨块被模制成在出口点处具有用于韧带的固定弯曲半径（60），以限制在关节弯曲和伸展期间施加于韧带的弯曲应力。

    FIBROUS TRACHEAL PATCH
    79.
    发明申请
    FIBROUS TRACHEAL PATCH 审中-公开

    公开(公告)号：WO2013025819A2

    公开(公告)日：2013-02-21

    申请号：PCT/US2012/050974

    申请日：2012-08-15

    Applicant: THE UNIVERSITY OF KANSAS ,  DETAMORE, Michael ,  OTT, Lindsey ,  WEATHERLY, Robert

    Inventor： DETAMORE, Michael ,  OTT, Lindsey ,  WEATHERLY, Robert

    IPC: A61L27/14 ,  A61L27/24 ,  A61F2/04

    CPC classification number: A61F2/04 ,  A61F2002/046 ,  A61F2250/0018 ,  A61F2250/0028 ,  A61L27/10 ,  A61L27/18 ,  A61L27/34 ,  A61L2300/414 ,  A61L2420/04 ,  A61L2420/08 ,  A61L2430/22 ,  C08L67/04

    Abstract: An implant can include a plurality of polymeric fibers associated together into a fibrous body. The fibrous body is capable of being shaped to fit a tracheal defect and capable of being secured in place by suture or by bioadhesive. The fibrous body can have aligned fibers (e.g., circumferentially aligned) or unaligned fibers. The fibrous body can be electrospun. The fibrous body can have a first characteristic in a first gradient distribution across at least a portion of the fibrous body. The fibrous body can include one or more structural reinforcing members, such as ribbon structural reinforcing members, which can be embedded in the plurality of fibers. The fibrous body can include one or more structural reinforcing members bonded to the fibers with liquid polymer as an adhesive, the liquid polymer having a substantially similar composition of the fibers.

    Abstract translation: 植入物可以包括与纤维体相关联的多个聚合物纤维。 纤维体能够成形为适合气管缺损并且能够通过缝线或通过生物粘附固定在适当的位置。 纤维体可以具有对准的纤维（例如，周向对准）或未对准的纤维。 纤维体可以电纺丝。 纤维体可以具有穿过纤维体的至少一部分的第一梯度分布的第一特征。 纤维体可以包括一个或多个可以嵌入多根纤维中的结构加强构件，例如带状结构增强构件。 纤维体可以包括一个或多个结合的增强部件，其结合到具有液体聚合物作为粘合剂的纤维上，该液体聚合物具有基本相似的纤维组成。

    ANISOTROPIC REINFORCEMENT AND RELATED METHOD THEREOF
    80.
    发明申请
    ANISOTROPIC REINFORCEMENT AND RELATED METHOD THEREOF 审中-公开
    各向异性加固及其相关方法

    公开(公告)号：WO2012006188A1

    公开(公告)日：2012-01-12

    申请号：PCT/US2011/042451

    申请日：2011-06-29

    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION ,  HOLMES, Jeffrey, W. ,  AILAWADI, Gorav ,  FOMOVSKY, Gregory, M.

    Inventor： HOLMES, Jeffrey, W. ,  AILAWADI, Gorav ,  FOMOVSKY, Gregory, M.

    IPC: A61F2/02

    CPC classification number: A61F2/02 ,  A61F2/2481 ,  A61F2250/0018 ,  A61F2250/0028

    Abstract: Anisotropic reinforcements and synthetic materials are provided in which the fibers, mesh, weave, or otherwise interlaced or networked components thereof are oriented in one direction so as to create greater stiffness and/or tension in the one direction of the patch relative to other directions of the reinforcement. Methods of producing such anisotropic reinforcements are provided. The anisotropic reinforcements are advantageously suitable for the surgical repair of incisions, openings, defects, etc. of the cardiovascular system and allow healing to occur while preserving mechanical function, particularly ventricular function.

    Abstract translation: 提供各向异性增强件和合成材料，其中纤维，网，织物或其它交错或网状部件在一个方向上取向，以便在贴片的一个方向上相对于其它方向产生更大的刚度和/或张力 加固。 提供了生产这种各向异性增强材料的方法。 各向异性增强件有利地适用于心血管系统的切口，开口，缺陷等的外科修复，并且允许在保持机械功能，特别是心室功能的同时发生愈合。

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