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    METHOD AND APPARATUS FOR GENERATING A SUPERFICIAL STRUCTURE
    5.
    发明申请
    METHOD AND APPARATUS FOR GENERATING A SUPERFICIAL STRUCTURE 审中-公开
    用于产生表面结构的方法和设备

    公开(公告)号：WO2018069874A1

    公开(公告)日：2018-04-19

    申请号：PCT/IB2017/056343

    申请日：2017-10-13

    Applicant: MACOR, Giorgio

    Inventor： MACOR, Giorgio

    IPC: B32B38/06 ,  B32B3/30 ,  B29C59/02 ,  B05D1/42

    Abstract: The present invention relates to a method and an apparatus for producing an embossing on a substrate by means of digital printing technology. The method provides for the application of an embossing liquid, for example water- based, on a non-polymerized resin layer and the following polymerization of the resin by means of UV curing.

    Abstract translation: 本发明涉及借助于数字印刷技术在衬底上产生压印的方法和装置。 该方法提供了在非聚合树脂层上施加压印液体，例如水基，然后通过UV固化进行树脂的聚合。

    COMPOSITIONS COMPRISING A POLYSACCHARIDE MATRIX FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS
    6.
    发明申请
    COMPOSITIONS COMPRISING A POLYSACCHARIDE MATRIX FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS 审中-公开
    包含多糖基质的组合物用于控制释放活性成分

    公开(公告)号：WO2018015364A1

    公开(公告)日：2018-01-25

    申请号：PCT/EP2017/068085

    申请日：2017-07-18

    Applicant: JOINTHERAPEUTICS S.R.L.

    Inventor： MORPURGO, Margherita ,  BIANCHINI, Giulio ,  CALLEGARO, Lanfranco

    IPC: A61K9/08 ,  A61K47/36 ,  A61K31/196 ,  A61K31/58 ,  A61P19/02 ,  A61K47/69

    Abstract: The present application describes compositions that can be used for the controlled release of pharmacological active ingredients from a viscoelastic aqueous polysaccharide matrix, and their potential use in the treatment of different stages of musculoskeletal diseases. The combination of drug release modulation and the viscoelastic nature of the composition makes possible the use thereof in the treatment of acute and chronic phases of musculoskeletal diseases characterized by an inflammatory state, and where a therapeutic effect and a viscosupplemental contribution are required.

    Abstract translation: 本申请描述了可用于从粘弹性含水多糖基质中控制释放药理学活性成分的组合物，以及它们在治疗肌肉骨骼疾病的不同阶段中的潜在用途。 药物释放调节和组合物的粘弹性性质的组合使得其可用于治疗以炎症状态为特征的肌肉骨骼疾病的急性和慢性阶段，并且其中需要治疗效果和粘性补充作用。

    POLYSACCHARIDE COMPOSITIONS FOR TISSUE REPAIR
    7.
    发明申请
    POLYSACCHARIDE COMPOSITIONS FOR TISSUE REPAIR 审中-公开
    多糖组合物用于组织修复

    公开(公告)号：WO2017211776A1

    公开(公告)日：2017-12-14

    申请号：PCT/EP2017/063639

    申请日：2017-06-06

    Applicant: JOINTHERAPEUTICS S.R.L.

    Inventor： CALLEGARO, Lanfranco ,  BRUN, Paola ,  BIANCHINI, Giulio

    IPC: A61K31/722 ,  A61K31/728 ,  A61P17/02 ,  A61P17/12 ,  A61P19/00 ,  A61P19/02 ,  A61P19/04

    Abstract: The present application describes polysaccharide compositions that can be used as modulators of cell proliferation processes and their use in tissue repair with fibrotic process inhibition. These modulation properties can be usefully used in tissue repair for the prevention of fibrotic processes and/or tissue adhesions in traumatic, post-surgical and chronic fibrotic processes associated to autoimmune diseases.

    Abstract translation: 本申请描述了可用作细胞增殖过程的调节剂的多糖组合物及其在纤维化过程抑制的组织修复中的用途。 这些调节特性可用于组织修复中，用于预防与自身免疫性疾病相关的创伤性，手术后和慢性纤维化过程中的纤维化过程和/或组织粘连。

    SELECTED AMIDE OF γ -HYDROXYBUTYRIC ACID AND USES THEREOF IN THE TREATMENT OF ALCOHOL MISUSE
    8.
    发明申请
    SELECTED AMIDE OF γ -HYDROXYBUTYRIC ACID AND USES THEREOF IN THE TREATMENT OF ALCOHOL MISUSE 审中-公开
    选择的γ-羟基丁酸酰胺及其在酒精治疗中的应用

    公开(公告)号：WO2017021438A1

    公开(公告)日：2017-02-09

    申请号：PCT/EP2016/068517

    申请日：2016-08-03

    Applicant: LABORATORIO FARMACEUTICO C.T. S.R.L.

    Inventor： CACCIAGLIA, Roberto ,  LOCHE, Antonella

    IPC: C07C235/06 ,  A61K31/16 ,  A61P25/32

    CPC classification number: C07C235/06

    Abstract: The present invention relates to a selected amide of γ-hydroxybutyric acid, a process of manufacture and uses thereof. The invention also includes a pharmaceutical composition comprising an effective amount of the selected compound of the invention for use in preventing or treating drug addiction, especially alcohol misuse or dependency.

    Abstract translation: 本发明涉及选择的γ-羟基丁酸酰胺，其制备方法和用途。 本发明还包括药物组合物，其包含有效量的本发明选择的化合物用于预防或治疗药物成瘾，特别是酒精滥用或依赖性。

    DERMOCOSMETIC FILLER AND USES THEREOF FOR AESTHETIC PURPOSES
    9.
    发明申请
    DERMOCOSMETIC FILLER AND USES THEREOF FOR AESTHETIC PURPOSES 审中-公开
    灭菌填充剂及其用于美容用途的用途

    公开(公告)号：WO2015125117A1

    公开(公告)日：2015-08-27

    申请号：PCT/IB2015/051302

    申请日：2015-02-20

    Applicant: MASTELLI S.R.L.

    Inventor： CATTARINI MASTELLI, Laura ,  CATTARINI MASTELLI, Giulia ,  CATTARINI MASTELLI, Silvia

    IPC: A61L27/18 ,  A61L27/52 ,  A61Q19/08 ,  A61K9/00

    CPC classification number: A61Q19/08 ,  A61K8/606 ,  A61K2800/91 ,  A61L27/18 ,  A61L27/52 ,  A61L2400/06 ,  A61L2430/34 ,  C08L77/04

    Abstract: The present invention relates to a filler and a filler composition based on polynucleotides comprising a nucleic acid polymer chain moiety with a molecular weight distribution from 0.5 to 3000 kDalton, the nucleic acid polymer chain moiety is at least partially crosslinked with a biocompatible crosslinking agent. The filler is applied for aesthetic purposes, in particular to increase the volume of areas of the body or to smooth wrinkles, furrows, skin folds, in particular localized on the face and for orthopedic applications. The progressive hydrolysis of free nucleotides allows the activation of their trophic effect on the tissues, integrating the filler effect with the tissue trophic effect.

    Abstract translation: 本发明涉及一种基于多核苷酸的填充剂和填充剂组合物，其包含分子量分布为0.5至3000kDa的核酸聚合物链部分，核酸聚合物链部分至少部分地与生物相容的交联剂交联。 填充剂用于美学目的，特别是增加身体的面积的体积或平滑皱纹，沟纹，皮肤褶皱，特别是局部在脸部和矫形应用上。 游离核苷酸的逐渐水解允许其对组织的营养作用的激活，将填充效应与组织营养作用相结合。

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