公开(公告)号：WO2023087090A1

公开(公告)日：2023-05-25

申请号：PCT/CA2021/051631

申请日：2021-11-18

Applicant: MAGELLAN THERAPEUTICS INC.

Inventor： FERNANDES, Francis V A

IPC: C07K14/47 ,  A61K38/17 ,  A61K48/00 ,  A61P37/00 ,  C07K19/00 ,  C12N5/10 ,  C12B9/64 ,  C12N15/12 ,  C12N15/85

Abstract: The invention relates to recombinant proteins useful in the treatment of diseases or disorders associated with MBL-2 deficiency. The invention also relates to nucleic acids encoding such recombinant proteins, expression vector comprising said nucleic acids, as well as and exosomes comprising the recombinant proteins, nucleic acids, and/or expression vectors. The invention also relates to cells comprising said recombinant proteins, nucleic acids, expression vectors, and/or exosomes. Disclosed herein are also methods of treating a diseases or disorders associated with MBL-2 deficiency.

公开(公告)号：WO2023039666A1

公开(公告)日：2023-03-23

申请号：PCT/CA2022/051369

申请日：2022-09-14

Applicant: HUAWEI TECHNOLOGIES CANADA CO., LTD. ,  SMITH, Stephen L. ,  SADEGHI, Armin ,  GILLULY, Barry

Inventor： YADMELLAT, Peyman ,  REZAEE, Kasra

IPC: B60W60/00 ,  B60W30/095 ,  B60W40/04

Abstract: Systems, methods and computer-readable media for selecting a trajectory for an autonomous vehicle are disclosed that include computing a current vehicle state for the autonomous vehicle based on observations by a sensing system; computing respective collision probability scores for a plurality of candidate trajectories based on the current vehicle state; computing respective information gain scores for the plurality of candidate trajectories based on the current vehicle state, the information gain score for each candidate trajectory indicating an respective information gain for a next planning horizon interval that is subsequent to the current planning horizon interval; and selecting a planned trajectory from the plurality of candidate trajectories based on the respective collision probability scores and respective information gain scores.

公开(公告)号：WO2023028702A1

公开(公告)日：2023-03-09

申请号：PCT/CA2022/051312

申请日：2022-08-30

Applicant: SHOPIFY INC.

Inventor： LANDRY, Christopher ,  CHEN, Angela ,  CAO, Nancy ,  NI, Andrew ,  ADOLPHE, Jacob ,  FUENZALIDA NUNEZ, Joaquin

IPC: H04L67/147 ,  G06F40/12 ,  G06F40/30 ,  G06F40/284 ,  H04L67/50

Abstract: Systems and methods are described for generating a dynamic label for a real-time communication session. An ongoing communication session is monitored to identify a content characteristic of the communication session. A size of a sliding window is determined based on the content characteristic, where the size of the sliding window defines a segment of the communication session to include in the most recent subset of communications. The most recent subset of communications is analyzed to identify relevant words based on one or more relevancy criteria. A dynamic label associated with the communication session is generated, where the dynamic label includes at least a selected one of the relevant words.

公开(公告)号：WO2023000108A1

公开(公告)日：2023-01-26

申请号：PCT/CA2022/051138

申请日：2022-07-22

Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA

Inventor： LIU, Yang ,  YU, Najiaowa ,  ZHANG, Lei ,  MOU, Anqi ,  SUN, Huijuan ,  MOHAMMED, Abdulnayeem

IPC: C02F11/145 ,  A01G18/00 ,  C02F5/00 ,  C02F11/00 ,  C05F7/00 ,  A23K50/80

Abstract: A method of pretreating wastewater sludge including applying an amount of at least 0.01 g/g TSS Ca(ClO)2 to wastewater sludge to enhance digestibility of the sludge and reduce phosphorus concentration therein and then allowing sufficient time for the wastewater sludge to densify to a treated sludge having a specific resistance to filtration (SRF) of 3 to 4 (1010 m/Kg). The resulting treated sludge composition being sterilized, free of harmful bacteria, and useful as a fertilizer, particularly for growing mushrooms.

公开(公告)号：WO2023283734A1

公开(公告)日：2023-01-19

申请号：PCT/CA2022/051089

申请日：2022-07-13

Applicant: THE UNIVERSITY OF WESTERN ONTARIO

Inventor： LAVDAS, Michael ,  BISWAS, Saumik ,  PASMAN, Elizabeth ,  ABDOU, Sherif ,  NGO, Gordon ,  FEDOROV, Kirill ,  ABDIC, Sejla ,  CECCHINI, Matthew

IPC: G01S13/88 ,  G01S15/89

Abstract: The system is for use with a tissue sample and includes a tray and an apparatus. The tray is for receiving the tissue sample in use and an apparatus. The apparatus includes: a support which receives the tray in use; a probe adapted to transmit waves and identify wave echoes; a tissue marking device; and a transporter adapted to: convey the probe over the tissue sample in use, the probe and the transporter being adapted such that, in use, information about the tissue sample is collected sufficient to permit a radiologist to identify structures which resemble lymph nodes in the tissue sample; and convey the tissue marking device to locations of interest which correspond to the locations of structures which resemble lymph nodes in the tissue sample.

公开(公告)号：WO2022266744A1

公开(公告)日：2022-12-29

申请号：PCT/CA2022/050606

申请日：2022-04-21

Applicant: BRAINWAVE RESEARCH CORPORATION

Inventor： RATHI, Ghanshyam ,  RATHI, Prisha

IPC: H04L9/00 ,  B60R25/24 ,  G06F16/27 ,  G06F21/44 ,  G08B13/196 ,  G16Y30/10 ,  H04W12/06 ,  H04L67/1097 ,  G07C9/00 ,  H04L63/08 ,  H04L63/0807 ,  H04L63/102 ,  H04L63/108 ,  H04L9/50 ,  H04W12/08 ,  H04W12/63 ,  H04W4/80

Abstract: An access control method and system that uses a physical proximity interface on a token dispenser device to obtain tokens on a blockchain which are used for subsequent access to a local network. The tokens are authenticated on the local network using proof of authority authentication. A client device can present a token to the local network from anywhere in the world in order to access at least one device on the local network. In an example, the method includes receiving, from the physical proximity interface of the token dispenser device, a token on a blockchain layer; presenting, to a node of the local network, the token; and receiving, from the node, successful authentication of the token by way of proof of authority authentication. The method can include, after the successful authentication of the token, authorizing the client device to access a device on the local network.

公开(公告)号：WO2022246567A1

公开(公告)日：2022-12-01

申请号：PCT/CA2022/050852

申请日：2022-05-26

Applicant: HUAWEI TECHNOLOGIES CANADA CO., LTD.

Inventor： MILYAVSKY, Matthew

IPC: H01L23/36 ,  H01L23/373 ,  H05K1/02 ,  H05K1/16

Abstract: A method is disclosed of mounting a heat sink through a printed circuit board to reach a component on the opposite side of a board. The heat sink is passed through a window in the board to contact a component at a predetermined pressure optimized for thermal performance at minimum stress. The heat sink is affixed in place on the printed circuit board using through-hole pins which can be soldered to maintain the heat sink's position and the predetermined pressure.

公开(公告)号：WO2022174329A1

公开(公告)日：2022-08-25

申请号：PCT/CA2022/050153

申请日：2022-02-03

Applicant: INDIE TECH LIMITED

Inventor： STONE, Sophia Gabrielle Contreras ,  SCOUFARIS, John Symeon

IPC: G06Q10/08 ,  G06Q10/04 ,  G06N20/00

Abstract: Methods and systems for determining a time-variant supplier variable related to a contract. The method includes receiving, by a processor having a supplier variable module, a user historical data set, a global historical data set and an external data set. The method includes generating, by the supplier variable module, a set of outcomes; outputting, by the supplier variable module, the set of outcomes. The set of outcomes comprises at least one time-variant supplier variable. In an example, the supplier variable module includes a supplier variable model, which includes a machine learning model.

公开(公告)号：WO2022165602A1

公开(公告)日：2022-08-11

申请号：PCT/CA2022/050166

申请日：2022-02-04

Applicant: HUAWEI TECHNOLOGIES CO., LTD. ,  PAL, Soumyasundar ,  ZHANG, Yingxue ,  COATES, Mark

Inventor： PAL, Soumyasundar ,  ZHANG, Yingxue ,  COATES, Mark

IPC: G06N7/00 ,  G06N3/02 ,  G06Q10/04

Abstract: Probabilistic spatiotemporal forecasting comprising acquiring a time series of observed states from a real-world system, each observed state corresponding to a respective time-step in the time series and including a set of data observations of the real-world system for the respective time-step. For each of a plurality of the time steps in the time series of observed states, a hidden state is generated for the time-step based on an observed state for a prior time-step and an approximated posterior distribution generated for a hidden state for the prior time-step. The use of an approximated posterior distribution can enable improved forecasting in complex, high dimensional settings.

公开(公告)号：WO2022147627A1

公开(公告)日：2022-07-14

申请号：PCT/CA2022/050023

申请日：2022-01-07

Applicant: HUAWEI TECHNOLOGIES CANADA CO., LTD.

Inventor： ZHOU, Kang ,  WU, Ke

IPC: H01P3/08

Abstract: Various substrate- integrated waveguide (SIW) filtering crossover systems are described. An example SIW filtering crossover system may include: a substrate; a top metal plate placed on top of the substrate; a bottom metal plate placed beneath the substrate; a plurality of metalized via-holes in the substrate connecting the top metal plate and the bottom metal plate; and a plurality of grounded-coplanar-waveguides (GCPWs) coupled to sidewalls of the crossover system, wherein each of the GCPWs connects the crossover system to a respective microstrip line for signal transmission between the respective microstrip line and the crossover system.