公开(公告)号：WO2008142448A2

公开(公告)日：2008-11-27

申请号：PCT/GB2008050360

申请日：2008-05-19

Applicant: DURHAM SCIENT CRYSTALS LTD ,  ROBINSON MAX ,  GIBSON GARY ,  RADLEY IAN ,  BASU ARNAB

Inventor： ROBINSON MAX ,  GIBSON GARY ,  RADLEY IAN ,  BASU ARNAB

IPC: G01N23/04 ,  G01N23/20 ,  G01N23/207 ,  G01V5/00

CPC classification number: G01N23/04 ,  G01N23/2076 ,  G01V5/0016

Abstract: A method of and apparatus for obtaining radiation transmission data and especially an image of an object which involves providing a radiation source such as an x-ray or gamma-ray source and a radiation detector system such as an x-ray or gamma-ray detection system spaced therefrom to define a scanning zone therebetween, the detector system being capable of detecting and collecting spectroscopically resolvable information about incident radiation; collecting a dataset of information about radiationincident at the detector and hence transmissivity of an object in the scanning zone at at least one and preferably a plurality of scanning positions from radiation transmitted through the object and received at the detector system; resolving each such dataset spectroscopically across a plurality of frequency bands within the spectrum of the source; wherein at least one of the said plurality of frequency bands corresponds to a characteristically scattered wavelength of a target species to be identified, andwherein the absence of or substantial reduction in a transmitted signal intensity at the frequency band is interpreted as the presence of the said target species. The resolved data is preferably resolved as one or more images.

Abstract translation: 一种用于获得辐射透射数据的方法和装置，特别是涉及提供诸如x射线或γ射线源的辐射源和诸如x射线或γ射线检测之类的放射线检测器系统的物体的图像 系统与其隔开以限定它们之间的扫描区域，所述检测器系统能够检测和收集关于入射辐射的光谱可解析信息; 收集关于在检测器处发生的辐射的信息的数据集，并且因此从穿过物体的辐射的至少一个且优选多个扫描位置收集在扫描区域中的物体的透射率，并在检测器系统处接收; 在光谱范围内的多个频带内光谱地解析每个这样的数据集; 其中所述多个频带中的至少一个频带对应于要识别的目标物种的特征散射波长，并且其中在频带处的发射信号强度的不存在或实质上减少被解释为存在所述目标 种类。 解析的数据优选地被解析为一个或多个图像。

公开(公告)号：WO2011046646A2

公开(公告)日：2011-04-21

申请号：PCT/US2010041632

申请日：2010-07-10

Applicant: MICROBIOTIX INC ,  BASU ARNAB ,  MILLS DEBRA M ,  PEET NORTON P ,  WILLIAMS JOHN D

Inventor： BASU ARNAB ,  MILLS DEBRA M ,  PEET NORTON P ,  WILLIAMS JOHN D

IPC: A61K31/5513

CPC classification number: A61K31/5513 ,  A61K31/18 ,  C07D213/74 ,  C07D215/40 ,  C07D243/12 ,  C07D249/10 ,  C07D307/71 ,  C07D405/06 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D471/04 ,  C07D491/22 ,  A61K2300/00

Abstract: Organic compounds showing the ability to inhibit viral glycoprotein (GP)-mediated entry of a filovirus into a host cell are disclosed. The disclosed filovirus entry inhibitor compounds are useful for treating, preventing, or reducing the spread of infections by filovirus including the type species Marburg virus (MARV) and Ebola virus (EBOV). Preferred inhibitors of the invention provide therapeutic agents for combating the Ivory Coast, Sudan, Zaire, Bundibugyo, and Reston Ebola virus strains.

Abstract translation: 公开了显示抑制病毒糖蛋白（GP）介导的病毒入宿主细胞的能力的有机化合物。 所公开的叶病毒入侵抑制剂化合物可用于治疗，预防或减少包括类型物种马尔堡病毒（MARV）和埃博拉病毒（EBOV）的病毒感染的扩散。 本发明优选的抑制剂提供用于对抗科特迪瓦海岸，苏丹，扎伊尔，Bundibugyo和Reston埃博拉病毒毒株的治疗剂。

公开(公告)号：WO2010058202A1

公开(公告)日：2010-05-27

申请号：PCT/GB2009/051542

申请日：2009-11-16

Applicant: DURHAM SCIENTIFIC CRYSTALS LIMITED ,  RADLEY, Ian ,  BASU, Arnab ,  ROBINSON, Max

Inventor： RADLEY, Ian ,  BASU, Arnab ,  ROBINSON, Max

IPC: G01V5/00 ,  G01V15/00

CPC classification number: G01T7/00

Abstract: A tracking device for tracking with a radioactive material, a container including such a device, a system using such devices, and a tracking method are described. The device has a radiation detector (10) associatable with a radioactive material (14) adapted to be placed in use within a container (1) defining a radiation-shielded enclosure (7) for containing a radioactive material, to detect radiation activity from the material (14); a RF identification module (12) associatable with the container (1), comprising a data register to store a unique product identification code, a processor with a data transfer link (11) to each of the radiation detector (10) and data register to receive and process a live data stream of activity data from the detector (10) and associate this with the unique product identification code in a processed data packet, and an antenna (13) to enable transmission of a data item comprising both the unique product identification code and processed activity data to a remote data capture means (16), at least the antenna (13) being adapted to sit outside the radiation-shielded enclosure.

Abstract translation: 描述了使用放射性物质跟踪的跟踪装置，包括这种装置的容器，使用这种装置的系统以及跟踪方法。 该装置具有辐射探测器（10），该放射线检测器（10）可与放射性物质（14）相关联，放射性材料（14）适于被放置在容器（1）内，所述容器（1）限定用于容纳放射性物质的辐射屏蔽外壳（7） 材料（14）; 与容器（1）相关联的RF识别模块（12），包括用于存储唯一产品识别码的数据寄存器，具有数据传输链路（11）到每个辐射检测器（10）的处理器和数据寄存器 接收并处理来自检测器（10）的活动数据的实时数据流，并将其与经处理的数据分组中的唯一产品识别码相关联，以及天线（13），以便能够传输包括唯一产品标识 代码和处理的活动数据到远程数据捕捉装置（16），至少天线（13）适于位于辐射屏蔽外壳之外。

公开(公告)号：WO2009004376A3

公开(公告)日：2009-02-26

申请号：PCT/GB2008050521

申请日：2008-06-30

Applicant: DURHAM SCIENT CRYSTALS LTD ,  BASU ARNAB ,  ROBINSON MAX

Inventor： BASU ARNAB ,  ROBINSON MAX

IPC: H01L31/10 ,  H01L31/0336 ,  H01L31/0352

CPC classification number: H01L31/0336 ,  H01L31/03529 ,  H01L31/1828 ,  Y02E10/543

Abstract: A semiconductor device structure comprising a first bulk crystal semiconductor material and a second bulk crystal semiconductor material provided on a surface of the first bulk crystal semiconductor material with or without a deliberate intermediate region, the second bulk crystal semiconductor material being a Group II-VI material dissimilar to the first bulk crystal semiconductor material, wherein portions of the first and/or second bulk crystal semiconductor material have been selectively removed to produce a patterned area of reduced thickness of the first and/or second bulk crystal semiconductor and preferably to expose a patterned area of the said surface of the first and/or second bulk crystal semiconductor material.

Abstract translation: 一种半导体器件结构，包括第一体晶半导体材料和第二体晶半导体材料，所述第一体晶半导体材料设置在具有或不具有有意中间区域的第一块状半导体材料的表面上，所述第二体晶半导体材料为II-VI族材料 不同于第一块体晶体半导体材料，其中第一和/或第二块状半导体材料的部分已被选择性地去除以产生第一和/或第二块状半导体的厚度减小的图案化区域，并且优选地暴露图案化 第一和/或第二块体半导体材料的所述表面的面积。

公开(公告)号：WO2008142446A3

公开(公告)日：2008-11-27

申请号：PCT/GB2008/050358

申请日：2008-05-19

Applicant: DURHAM SCIENTIFIC CRYSTALS LTD ,  ROBINSON, Max ,  RADLEY, Ian ,  GIBSON, Gary ,  BASU, Arnab

Inventor： ROBINSON, Max ,  RADLEY, Ian ,  GIBSON, Gary ,  BASU, Arnab

IPC: G01N23/04 ,  G01V5/00 ,  G01N23/087

Abstract: A method and apparatus for obtaining radiation transmission data comprising information about the composition of an object are described. The principle involves providing a radiation source such as an x-ray or gamma-ray source and a radiation detector system such as an x-ray or gamma-ray detector system, the detector system being capable of detecting and collecting spectroscopically resolvable information about incident radiation; collecting a dataset of information about radiation incident at the detector; resolving the dataset spectroscopically.across a plurality of frequency bands within the spectrum of the source to produce a corresponding plurality of frequency-specific datasets; determining an intensity ratio for at least one pair of frequency specific datasets; using this to identify materials present.

公开(公告)号：WO2008142395A1

公开(公告)日：2008-11-27

申请号：PCT/GB2008/001713

申请日：2008-05-16

Applicant: DURHAM SCIENTIFIC CRYSTALS LTD ,  BASU, Arnab ,  CANTWELL, Ben ,  ROBINSON, Max

Inventor： BASU, Arnab ,  CANTWELL, Ben ,  ROBINSON, Max

IPC: C30B23/06 ,  C30B29/48

CPC classification number: C30B23/06 ,  C23C16/42 ,  C23C16/46 ,  C30B25/10 ,  C30B29/48 ,  C30B35/002 ,  Y10T117/10

Abstract: Apparatus for vapour phase growing of crystals having a single multi-zone heater arranged to heat a heated zone to give a predetermined temperature profile along the length of the heated zone. A generally U-shaped tube having a first limb, a second limb, and a linkage connecting the first alid second limbs is located on the heated zone. The first limb contains a source material. The second limb supports a seed such that the source material and seed are spaced longitudinally within the heated zone to provide a predetermined temperature differential between the source and seed. The crystal is grown on the seed.

Abstract translation: 用于气相生长具有单个多区加热器的晶体的装置，其布置成加热加热区以沿着加热区的长度给出预定的温度分布。 具有第一肢体，第二肢体和连接第一齿状第二肢体的连接件的大致U形管位于加热区域上。 第一肢含有源材料。 第二肢支撑种子，使得源材料和种子在加热区域内纵向隔开，以在源和种子之间提供预定的温差。 晶体生长在种子上。

公开(公告)号：WO2007072021A1

公开(公告)日：2007-06-28

申请号：PCT/GB2006/004859

申请日：2006-12-21

Applicant: DURHAM SCIENTIFIC CRYSTALS LIMITED ,  BASU, Arnab ,  ROBINSON, Max ,  CANTWELL, Ben ,  BRINKMAN, Andy

Inventor： BASU, Arnab ,  ROBINSON, Max ,  CANTWELL, Ben ,  BRINKMAN, Andy

IPC: H01L29/18 ,  H01L29/221 ,  H01L29/765 ,  H01L29/772 ,  H01L31/0296 ,  H01L31/08 ,  H01L31/115 ,  H01L27/146 ,  H01L31/0304

CPC classification number: H01L31/0296 ,  H01L27/14658 ,  H01L27/14676 ,  H01L27/14696 ,  H01L29/2203 ,  H01L29/225 ,  H01L29/227 ,  H01L29/267 ,  H01L31/0304 ,  H01L31/085 ,  H01L31/115 ,  H01L31/1828 ,  Y02E10/543

Abstract: Semiconductor device structure and method of manufacture therefore having a first bulk single crystal semiconductor material, an interfacial region provided on the first bulk single crystal semiconductor material, and a second bulk single crystal semiconductor material. The second bulk single crystal semiconductor material is a group II-VI material dissimilar to the first bulk single crystal semiconductor material. The interfacial region including at least one film of a group II-VI material. The interfacial region may have more than one film.

Abstract translation: 因此，半导体器件结构和制造方法具有第一块体单晶半导体材料，设置在第一块体单晶半导体材料上的界面区域和第二块体单晶半导体材料。 第二块体单晶半导体材料是与第一块体单晶半导体材料不同的II-VI族材料。 界面区域包括至少一种II-VI族材料的膜。 界面区域可以具有多于一个的膜。

公开(公告)号：WO2006090104A1

公开(公告)日：2006-08-31

申请号：PCT/GB2006/000354

申请日：2006-02-02

Applicant: DURHAM SCIENTIFIC CRYSTALS LIMITED ,  BASU, Arnab ,  ROBINSON, Max ,  CANTWELL, Ben ,  BRINKMAN, Andy

Inventor： BASU, Arnab ,  ROBINSON, Max ,  CANTWELL, Ben ,  BRINKMAN, Andy

IPC: C30B23/00 ,  C30B29/48

CPC classification number: C30B23/005 ,  C30B23/002 ,  C30B23/02 ,  C30B23/025 ,  C30B29/48 ,  C30B29/66 ,  Y10T117/10 ,  Y10T117/1004

Abstract: The present invention relates to an apparatus for vapour phase crystal growth to produce multiple single crystals in one growth cycle comprising one central source chamber, a plurality of growth chambers, a plurality of passage means adapted for transport of vapour from the source chamber to the growth chambers, wherein the source chamber is thermally decoupled from the growth chambers.

Abstract translation: 本发明涉及用于在一个生长循环中产生多个单晶的气相晶体生长的装置，包括一个中心源室，多个生长室，适于将蒸气从源室输送到生长的多个通道装置 室，其中源室与生长室热分离。

公开(公告)号：WO2011046646A3

公开(公告)日：2011-04-21

申请号：PCT/US2010/041632

申请日：2010-07-10

Applicant: MICROBIOTIX, INC. ,  BASU, Arnab ,  MILLS, Debra, M. ,  PEET, Norton, P. ,  WILLIAMS, John, D.

Inventor： BASU, Arnab ,  MILLS, Debra, M. ,  PEET, Norton, P. ,  WILLIAMS, John, D.

IPC: A01N43/62 ,  A61K31/55

Abstract: Organic compounds showing the ability to inhibit viral glycoprotein (GP)-mediated entry of a filovirus into a host cell are disclosed. The disclosed filovirus entry inhibitor compounds are useful for treating, preventing, or reducing the spread of infections by filovirus including the type species Marburg virus (MARV) and Ebola virus (EBOV). Preferred inhibitors of the invention provide therapeutic agents for combating the Ivory Coast, Sudan, Zaire, Bundibugyo, and Reston Ebola virus strains.

公开(公告)号：WO2008142448A4

公开(公告)日：2009-03-05

申请号：PCT/GB2008050360

申请日：2008-05-19

Applicant: DURHAM SCIENT CRYSTALS LTD ,  ROBINSON MAX ,  GIBSON GARY ,  RADLEY IAN ,  BASU ARNAB

Inventor： ROBINSON MAX ,  GIBSON GARY ,  RADLEY IAN ,  BASU ARNAB

IPC: G01N23/04 ,  G01N23/20 ,  G01N23/207 ,  G01V5/00

CPC classification number: G01N23/04 ,  G01N23/2076 ,  G01V5/0016

Abstract: A method of and apparatus for obtaining radiation transmission data and especially an image of an object which involves providing a radiation source such as an x-ray or gamma-ray source and a radiation detector system such as an x-ray or gamma-ray detection system spaced therefrom to define a scanning zone therebetween, the detector system being capable of detecting and collecting spectroscopically resolvable information about incident radiation; collecting a dataset of information about radiationincident at the detector and hence transmissivity of an object in the scanning zone at at least one and preferably a plurality of scanning positions from radiation transmitted through the object and received at the detector system; resolving each such dataset spectroscopically across a plurality of frequency bands within the spectrum of the source; wherein at least one of the said plurality of frequency bands corresponds to a characteristically scattered wavelength of a target species to be identified, andwherein the absence of or substantial reduction in a transmitted signal intensity at the frequency band is interpreted as the presence of the said target species. The resolved data is preferably resolved as one or more images.

Abstract translation: 一种用于获得辐射透射数据的方法和装置，特别是涉及提供诸如x射线或γ射线源的辐射源和诸如x射线或γ射线检测之类的放射线检测器系统的物体的图像 系统与其隔开以限定它们之间的扫描区域，所述检测器系统能够检测和收集关于入射辐射的光谱可解析信息; 收集关于在检测器处发生的辐射的信息的数据集，并且因此从穿过物体的辐射的至少一个且优选多个扫描位置收集在扫描区域中的物体的透射率，并在检测器系统处接收; 在光谱范围内的多个频带内光谱地解析每个这样的数据集; 其中所述多个频带中的至少一个频带对应于要识别的目标物种的特征散射波长，并且其中在频带处的发射信号强度的不存在或实质上减少被解释为存在所述目标 种类。 解析的数据优选地被解析为一个或多个图像。