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    MULTI-FUNCTIONAL BURR HOLE ASSEMBLY
    2.
    发明申请
    MULTI-FUNCTIONAL BURR HOLE ASSEMBLY 审中-公开
    多功能BURR HOLE组装

    公开(公告)号：WO2009099701A2

    公开(公告)日：2009-08-13

    申请号：PCT/US2009/030520

    申请日：2009-01-09

    Applicant: INTELECT MEDICAL, INC. ,  CARLTON, Keith ,  GRESZLER, Alan ,  KOKONES, Scott

    Inventor： CARLTON, Keith ,  GRESZLER, Alan ,  KOKONES, Scott

    IPC: A61N1/05

    CPC classification number: A61N1/0529 ,  A61B5/01 ,  A61B5/031 ,  A61B5/0476 ,  A61B5/6864 ,  A61B2562/0219 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/086 ,  A61N1/36082 ,  A61N1/3718

    Abstract: A burr hole assembly for use in neurosurgery. In one aspect, the burr hole assembly comprises a burr hole portion and one or more sensors, such as EEG sensors, temperature sensors, intracranial pressure sensors, or motion sensors. In certain embodiments, an input/output unit, which may include a multiplexer, provides a coupling between the sensors and a brain stimulation system which operates in cooperation with the burr hole assembly. In another aspect, the burr hole assembly comprises a burr hole portion and a rotation mechanism which operates in cooperation with an electrode lead. In certain embodiments, the burr hole assembly includes a control system for controlling the rotation mechanism. Also disclosed are systems comprising a burr hole assembly and various components of a brain stimulation system, such as pulse generators, electrode leads, lead extension, or external control systems.

    Abstract translation:

    用于神经外科手术的钻孔组件。 在一个方面，毛刺孔组件包括毛刺孔部分和一个或多个传感器，诸如EEG传感器，温度传感器，颅内压力传感器或运动传感器。 在某些实施例中，可以包括多路复用器的输入/输出单元提供传感器和与刺孔组合配合操作的脑刺激系统之间的耦合。 另一方面，毛刺孔组件包括毛刺孔部分和与电极引线配合工作的旋转机构。 在某些实施例中，毛刺孔组件包括用于控制旋转机构的控制系统。 还公开了包括毛刺孔组件和脑刺激系统的各种部件（诸如脉冲发生器，电极引线，引线延伸部分或外部控制系统）的系统。

    NEUROMODULATION USING ENERGY-EFFICIENT WAVEFORMS
    4.
    发明申请
    NEUROMODULATION USING ENERGY-EFFICIENT WAVEFORMS 审中-公开
    使用能量效应波形进行神经网络化

    公开(公告)号：WO2010141154A1

    公开(公告)日：2010-12-09

    申请号：PCT/US2010/031741

    申请日：2010-04-20

    Applicant: INTELECT MEDICAL, INC. ,  YORK, Randall ,  KOKONES, Scott ,  CARLTON, Keith ,  GRESZLER, Alan

    Inventor： YORK, Randall ,  KOKONES, Scott ,  CARLTON, Keith ,  GRESZLER, Alan

    IPC: A61N1/00

    CPC classification number: A61N1/36103 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/36067 ,  A61N1/36082 ,  A61N1/3615

    Abstract: Methods of neuromodulation in a live mammalian subject, such as a human patient The method comprises applying an electrical signal to a target site in the nervous system, such as the brain, where the electrical signal comprises a series of pulses. The pulses includes a waveform shape that is more energy-efficient as compared to a corresponding rectangular waveform. Non-limiting examples of such energy-efficient waveforms include linear increasing, linear decreasing, exponential increasing, exponential decreasing, and Gaussian waveforms. Also described are apparatuses for neuromodulation and software for operating such apparatuses.

    Abstract translation: 活体哺乳动物受试者（例如人类患者）中神经调节的方法该方法包括将电信号施加到神经系统（例如脑）中的目标部位，其中电信号包括一系列脉冲。 脉冲包括与对应的矩形波形相比更节能的波形形状。 这种能量效率波形的非限制性实例包括线性增加，线性递减，指数增加，指数减小和高斯波形。 还描述了用于神经调节的装置和用于操作这种装置的软件。

    MULTI-FUNCTIONAL BURR HOLE ASSEMBLY
    6.
    发明申请
    MULTI-FUNCTIONAL BURR HOLE ASSEMBLY 审中-公开
    多功能双孔组件

    公开(公告)号：WO2009099701A3

    公开(公告)日：2009-12-03

    申请号：PCT/US2009030520

    申请日：2009-01-09

    Applicant: INTELECT MEDICAL INC ,  CARLTON KEITH ,  GRESZLER ALAN ,  KOKONES SCOTT

    Inventor： CARLTON KEITH ,  GRESZLER ALAN ,  KOKONES SCOTT

    IPC: A61N1/05 ,  A61B5/03 ,  A61B5/0476 ,  A61N1/08 ,  A61N1/36

    CPC classification number: A61N1/0529 ,  A61B5/01 ,  A61B5/031 ,  A61B5/0476 ,  A61B5/6864 ,  A61B2562/0219 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/086 ,  A61N1/36082 ,  A61N1/3718

    Abstract: A burr hole assembly for use in neurosurgery. In one aspect, the burr hole assembly comprises a burr hole portion and one or more sensors, such as EEG sensors, temperature sensors, intracranial pressure sensors, or motion sensors. In certain embodiments, an input/output unit, which may include a multiplexer, provides a coupling between the sensors and a brain stimulation system which operates in cooperation with the burr hole assembly. In another aspect, the burr hole assembly comprises a burr hole portion and a rotation mechanism which operates in cooperation with an electrode lead. In certain embodiments, the burr hole assembly includes a control system for controlling the rotation mechanism. Also disclosed are systems comprising a burr hole assembly and various components of a brain stimulation system, such as pulse generators, electrode leads, lead extension, or external control systems.

    Abstract translation: 用于神经外科的钻孔组件。 一方面，毛刺孔组件包括毛刺孔部分和一个或多个传感器，例如EEG传感器，温度传感器，颅内压力传感器或运动传感器。 在某些实施例中，可包括多路复用器的输入/输出单元提供传感器与与钻孔组件协作操作的脑刺激系统之间的耦合。 另一方面，毛刺孔组件包括与电极引线配合操作的毛刺孔部分和旋转机构。 在某些实施例中，钻孔组件包括用于控制旋转机构的控制系统。 还公开了包括钻孔组件和脑刺激系统的各种部件的系统，例如脉冲发生器，电极引线，引线延伸或外部控制系统。

    DIRECTIONAL ELECTRODE DEVICES WITH LOCATING FEATURES
    9.
    发明申请
    DIRECTIONAL ELECTRODE DEVICES WITH LOCATING FEATURES 审中-公开
    具有定位特征的方向电极装置

    公开(公告)号：WO2009102508A1

    公开(公告)日：2009-08-20

    申请号：PCT/US2009/030516

    申请日：2009-01-09

    Applicant: INTELECT MEDICAL, INC. ,  CARLTON, Keith ,  GRESZLER, Alan ,  KOKONES, Scott

    Inventor： CARLTON, Keith ,  GRESZLER, Alan ,  KOKONES, Scott

    IPC: A61N1/05

    CPC classification number: A61N1/0529 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/0551 ,  A61N1/36182

    Abstract: Electrode devices having directional electrodes for use in deep brain stimulation or other uses. In one aspect, an electrode assembly comprises an elongate lead and a lead guide that are engageable with each other in a coaxial relationship. When the elongate lead and the lead guide are engaged with each other, the two components are rotationally fixed in relation to each other, hi another aspect, an elongate lead comprises a radiologically-visible feature for indicating the orientation of the elongate lead. In yet another aspect, an electrode system is capable of determining the position and/or orientation of an electrode positioned within a body. In other aspects, methods for electrically stimulating a target site in the body are disclosed.

    Abstract translation: 具有用于深部脑刺激或其他用途的定向电极的电极装置。 在一个方面，电极组件包括可以同轴关系彼此接合的细长引线和引线引导件。 当细长引线和引线引导件彼此接合时，两个部件相对于彼此旋转地固定。另一方面，细长引线包括用于指示细长引线的取向的放射线可见特征。 在另一方面，电极系统能够确定位于身体内的电极的位置和/或取向。 在其它方面，公开了用于电刺激身体中的靶位点的方法。

    LIQUID CLEANING AND STERILIZATION SYSTEM AND METHOD
    10.
    发明申请
    LIQUID CLEANING AND STERILIZATION SYSTEM AND METHOD 审中-公开
    液体清洗灭菌系统及方法

    公开(公告)号：WO0156615A3

    公开(公告)日：2002-01-03

    申请号：PCT/US0103937

    申请日：2001-02-07

    Applicant: STERIS INC ,  SANFORD BILL R ,  KRAL JUDE A ,  TVERGYAK JOSEPH ,  MOSS BERNARD J ,  PRIEST ROBERT M ,  HLEBOVY JAMES C ,  KELSCH DANIEL N ,  GRESZLER ALAN J ,  MINEROVIC DAVID E ,  HOUSTON JOHN C ,  ROBINSON NANCY A

    Inventor： SANFORD BILL R ,  KRAL JUDE A ,  TVERGYAK JOSEPH ,  MOSS BERNARD J ,  PRIEST ROBERT M ,  HLEBOVY JAMES C ,  KELSCH DANIEL N ,  GRESZLER ALAN J ,  MINEROVIC DAVID E ,  HOUSTON JOHN C ,  ROBINSON NANCY A

    IPC: A61B1/12 ,  A61L2/18 ,  A61L2/24

    CPC classification number: B08B9/00 ,  A61B1/00057 ,  A61B1/123 ,  A61B1/125 ,  A61L2/18 ,  A61L2/24 ,  B08B3/02

    Abstract: A fluid delivery system (26) for an automated processor (A) delivers washing, microbial decontaminant, and rinse fluids to spray nozzles (102, 104, 106, 108, 110) in a chamber (12) for sequentially spraying the fluids over a lumened device (B), such as a n endoscope. The fluid delivery system also delivers the fluids to connection ports (150, 152, 154) which connect with internal passages (187) of the device for delivering the fluids thereto. Leaking connectors (184) connect the automated processor connection ports with inlet ports (196) of the device and allow a portion of the washing, decontaminant, and rinsing solutions to leak from each inlet port. The endoscope is supported on a rack which is agitated by an activation system (330). A computer control system (80) controls cleaning, decontamination, rinsing, and drying stages of a cycle, which are all carried out within the chamber, obviating the need for human contact with the device during processing. A door locking and latching mechanism (90) ensures that the door remains locked during the washing, decontamination, and rinse cycle to avoid accidental injury to an operator from strong chemicals used in the system.

    Abstract translation: 用于自动处理器（A）的流体输送系统（26）将洗涤，微生物净化剂和冲洗流体输送到在腔室（12）中的喷嘴（102,104,106,108,110），以将流体顺序地喷洒在 流明装置（B），诸如内窥镜。 流体输送系统还将流体输送到与装置的内部通道（187）连接的连接端口（150,152,154），以将流体输送到其上。 泄漏连接器（184）将自动处理器连接端口与设备的入口端口（196）连接，并允许一部分洗涤，去污剂和冲洗溶液从每个入口端口泄漏。 内窥镜被支撑在由激活系统（330）搅动的支架上。 计算机控制系统（80）控制循环的清洁，净化，漂洗和干燥阶段，这些阶段都在室内进行，从而避免了在处理过程中与人体接触的需要。 门锁和闩锁机构（90）确保在洗涤，去污和漂洗周期期间门保持锁定，以避免操作者因系统中使用的强烈化学物质而造成意外伤害。

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