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公开(公告)号：WO2009100102A3
公开(公告)日：2010-04-22
申请号：PCT/US2009033027
申请日：2009-02-04
Applicant: DANISCO US INC GENENCOR DIV , CASCAO-PEREIRA LUIS , CHANG CLAUDINE , CHOY CLEMENT , ESTABROOK MELODIE , JONES BRIAN E , KELLIS JAMES T JR , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER , WEYLER WALTER
Inventor： CASCAO-PEREIRA LUIS , CHANG CLAUDINE , CHOY CLEMENT , ESTABROOK MELODIE , JONES BRIAN E , KELLIS JAMES T JR , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER , WEYLER WALTER
CPC classification number: C12N9/2417 , A21D8/042 , A23K20/189 , A23K50/75 , A23L29/06
Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
Abstract translation: 描述了具有α-淀粉酶活性并且相对于母体α-淀粉酶具有改变的性质的亲本α-淀粉酶的变体（突变体）及其使用方法。
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2.发明申请
公开(公告)号：WO2005052146A3
公开(公告)日：2005-06-09
申请号：PCT/US2004/039066
申请日：2004-11-19
Applicant: GENENCOR INTERNATIONAL, INC. , THE PROCTER & GAMBLE COMPANY , JONES, Brian, Edward , KOLKMAN, Marc , LEEFLANG, Chris , OH, Hiroshi , POULOSE, Ayrookaran, J. , SADLOWSKI, Eugene, S. , SHAW, Andrew , VAN DER KLEIJ, Wilhelmus, A., H. , VAN MARREWIJK, Leo
Inventor： JONES, Brian, Edward , KOLKMAN, Marc , LEEFLANG, Chris , OH, Hiroshi , POULOSE, Ayrookaran, J. , SADLOWSKI, Eugene, S. , SHAW, Andrew , VAN DER KLEIJ, Wilhelmus, A., H. , VAN MARREWIJK, Leo
IPC: C12N15/53
Abstract: The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions ( e.g. , detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant ( i.e. , variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
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3.发明申请
公开(公告)号：WO2009098229A3
公开(公告)日：2010-05-27
申请号：PCT/EP2009051268
申请日：2009-02-04
Applicant: DANISCO US INC GENENCOR DIV , DANISCO , KRAGH KARSTEN MATTHIAS , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER WILLEM , WEYLER WALTER , PEREIRA LUIS GUSTAVO CASCAO , KELLIS JAMES T
Inventor： KRAGH KARSTEN MATTHIAS , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER WILLEM , WEYLER WALTER , PEREIRA LUIS GUSTAVO CASCAO , KELLIS JAMES T
CPC classification number: C12N9/2417 , A21D8/042 , A23K20/189 , A23K50/75 , A23L29/06
Abstract: The present invention relates to the use of a parent AmyTS-23 alpha-amylase as well as variants, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase in the production of food products, such as the use in a baking composition.
Abstract translation: 本发明涉及母体AmyTS-23α-淀粉酶以及变体，其中变体具有α-淀粉酶活性并在食品生产中相对于母体α-淀粉酶具有改变的性质，例如使用 在烘焙组合物中。
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4.发明申请SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 审中-公开丝氨酸蛋白酶，核酸编码丝氨酸酶和载体和宿主细胞
公开(公告)号：WO2005052146A8
公开(公告)日：2006-08-24
申请号：PCT/US2004039066
申请日：2004-11-19
Applicant: GENENCOR INT , PROCTER & GAMBLE , JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , OH HIROSHI , POULOSE AYROOKARAN J , SADLOWSKI EUGENE S , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
Inventor： JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , OH HIROSHI , POULOSE AYROOKARAN J , SADLOWSKI EUGENE S , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
CPC classification number: C12N9/52 , C07K2299/00 , C11D3/386
Abstract: The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
Abstract translation: 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新型遗传物质，以及从微球菌属（Micrococcineae spp。）获得的蛋白水解蛋白，包括但不限于纤维单胞菌属（Cellulomonas spp） 和从其开发的变体蛋白质。 特别地，本发明提供了从纤维单胞菌属（Splulomonas spp）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的载体，载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物，以及包含从微球菌（Micrococcineae spp。）获得的蛋白酶的纺织和皮革加工组合物，其包括但不限于纤维单胞菌属（Cellulomonas spp） 在替代实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些突变型蛋白酶也可用于许多应用。
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5.发明申请SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 审中-公开丝氨酸蛋白酶，编码丝氨酸酶的核酸以及包含相同物质的载体和宿主细胞
公开(公告)号：WO2005052161A2
公开(公告)日：2005-06-09
申请号：PCT/US2004/039006
申请日：2004-11-19
Applicant: GENENCOR INTERNATIONAL, INC. , JONES, Brian, Edward , KOLKMAN, Marc , LEEFLANG, Chris , POULOSE, Ayrookaran, J. , SHAW, Andrew , VAN DER KLEIJ, Wilhelmus, A., H. , VAN MARREWIJK, Leo
Inventor： JONES, Brian, Edward , KOLKMAN, Marc , LEEFLANG, Chris , POULOSE, Ayrookaran, J. , SHAW, Andrew , VAN DER KLEIJ, Wilhelmus, A., H. , VAN MARREWIJK, Leo
IPC: C12N15/53
CPC classification number: C12N9/52 , C07K2299/00 , C11D3/386
Abstract: The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
Abstract translation: 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新型遗传物质和从微球菌属物种获得的蛋白水解蛋白质，包括但不限于纤维单胞菌属， 我>属。 和由其开发的变体蛋白。 具体地说，本发明提供了由纤维单胞菌属（Cellulomonas spp。）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主产生的酶 细胞。 本发明还提供了从微球菌属物种获得的包含蛋白酶的清洁组合物（例如洗涤剂组合物），动物饲料组合物和纺织品和皮革加工组合物，包括但不限于纤维单胞的属。 在替代实施方案中，本发明提供了衍生自本文所述野生型蛋白酶的突变（即，变体）蛋白酶。 这些突变蛋白酶也可用于多种应用。
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Patent Agency Ranking6.发明申请SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 审中-公开丝氨酸蛋白酶，编码丝氨酸酶的核酸以及包含相同物质的载体和宿主细胞
公开(公告)号：WO2005052146A2
公开(公告)日：2005-06-09
申请号：PCT/US2004039066
申请日：2004-11-19
Applicant: GENENCOR INT , PROCTER & GAMBLE , JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , OH HIROSHI , POULOSE AYROOKARAN J , SADLOWSKI EUGENE S , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
Inventor： JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , OH HIROSHI , POULOSE AYROOKARAN J , SADLOWSKI EUGENE S , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
CPC classification number: C12N9/52 , C07K2299/00 , C11D3/386
Abstract: The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
Abstract translation: 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新颖遗传物质和从微球菌属物种获得的蛋白水解蛋白，包括但不限于纤维单胞菌属物种。 和由其开发的变体蛋白。 具体而言，本发明提供了由纤维单胞菌属（Cellulomonas spp）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了包含从微球菌属物种获得的蛋白酶的清洁组合物（例如洗涤剂组合物），动物饲料组合物和纺织品和皮革加工组合物，所述蛋白酶包括但不限于纤维单胞菌属物种。 在替代实施方案中，本发明提供了衍生自本文所述野生型蛋白酶的突变（即，变体）蛋白酶。 这些突变蛋白酶也可用于多种应用。
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7.发明申请VARIANTS OF BACILLUS sup. TS-23 ALPHA-AMYLASE WITH ALTERED PROPERTIES 审中-公开BACILLUS的变种sup。 具有改性特性的TS-23 ALPHA-AMYLASE
公开(公告)号：WO2009061380A4
公开(公告)日：2009-11-05
申请号：PCT/US2008012412
申请日：2008-11-03
Applicant: DANISCO US INC GENENCOR DIV , SHAW ANDREW , RAMER SANDRA , POWER SCOTT D , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN E , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMAN CASPER , WEYLER WALTER , KRAGH KARSTEN M , GOYAL MANSI , GRAYCAR THOMAS , HUANG VICTORIA
Inventor： SHAW ANDREW , RAMER SANDRA , POWER SCOTT D , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN E , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMAN CASPER , WEYLER WALTER , KRAGH KARSTEN M , GOYAL MANSI , GRAYCAR THOMAS , HUANG VICTORIA
CPC classification number: C11D3/386 , C11D3/38681 , C12N9/2417
Abstract: Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased themostability, reduced calcium dependence, increased washing / cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.
Abstract translation: 芽孢杆菌的变种 TS-23菌株α-淀粉酶表现出改善的酶性能，包括增加其稳定性，降低钙依赖性，提高洗涤/清洁性能和烘烤能力。 包含这些变体的组合物可用于淀粉加工，淀粉液化，粉化，淀粉糖化，清洗，洗衣，纺织品退浆，烘烤和生物膜除去的方法。
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8.发明申请
公开(公告)号：WO2009098229A2
公开(公告)日：2009-08-13
申请号：PCT/EP2009/051268
申请日：2009-02-04
Applicant: Danisco US Inc., Genencor Division , Danisco A/S , KRAGH, Karsten, Matthias , CHANG, Claudine , ESTABROOK, Melodie , JONES, Brian , CHOY, Clement , KOLKMAN, Marc , LEEFLANG, Chris , VROEMEN, Casper, Willem , WEYLER, Walter , PEREIRA, Luis, Gustavo, Cascão , KELLIS, James T.
Inventor： KRAGH, Karsten, Matthias , CHANG, Claudine , ESTABROOK, Melodie , JONES, Brian , CHOY, Clement , KOLKMAN, Marc , LEEFLANG, Chris , VROEMEN, Casper, Willem , WEYLER, Walter , PEREIRA, Luis, Gustavo, Cascão , KELLIS, James T.
IPC: A21D2/00
CPC classification number: C12N9/2417 , A21D8/042 , A23K20/189 , A23K50/75 , A23L29/06
Abstract: The present invention relates to the use of a parent AmyTS-23 alpha-amylase as well as variants, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase in the production of food products, such as the use in a baking composition.
Abstract translation: 本发明涉及母体AmyTS-23α-淀粉酶以及变体，其中变体具有α-淀粉酶活性并在食品生产中相对于母体α-淀粉酶具有改变的性质，例如使用 在烘焙组合物中。
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公开(公告)号：WO2009058679A1
公开(公告)日：2009-05-07
申请号：PCT/US2008/081088
申请日：2008-10-24
Applicant: DANISCO US INC., GENENCOR DIVISION , JONES, Brian E. , KOLKMAN, Marc , LEEFLANG, Chris
Inventor： JONES, Brian E. , KOLKMAN, Marc , LEEFLANG, Chris
CPC classification number: C12N9/52 , A23K20/189 , A23K50/75 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/38681
Abstract: The present invention provides Streptomyces serine proteases. In some embodiments, the protease comprises an amino acid sequence that is at least about 80% identical to the wild type Streptomyces 1AG3 protease. The present invention also provides isolated nucleic acid sequences, recombinant nucleic acids, and host cells containing the recombinant nucleic acids are also provided. In addition, the present invention provides cleaning and other compositions comprising Streptomyces serine protease.
Abstract translation: 本发明提供链霉菌丝氨酸蛋白酶。 在一些实施方案中，蛋白酶包含与野生型链霉菌1AG3蛋白酶至少约80％相同的氨基酸序列。 本发明还提供了分离的核酸序列，重组核酸和含有重组核酸的宿主细胞。 此外，本发明提供了包含链霉菌丝氨酸蛋白酶的清洁剂和其它组合物。
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10.发明申请SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 审中-公开丝氨酸蛋白酶，核酸编码丝氨酸酶和载体和宿主细胞
公开(公告)号：WO2005052161A3
公开(公告)日：2005-11-03
申请号：PCT/US2004039006
申请日：2004-11-19
Applicant: GENENCOR INT , JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , POULOSE AYROOKARAN J , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
Inventor： JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , POULOSE AYROOKARAN J , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
CPC classification number: C12N9/52 , C07K2299/00 , C11D3/386
Abstract: The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
Abstract translation: 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新型遗传物质，以及从微球菌属（Micrococcineae spp。）获得的蛋白水解蛋白，包括但不限于纤维单胞菌属（Cellulomonas spp） 和从其开发的变体蛋白质。 特别地，本发明提供了从纤维单胞菌属（Splulomonas spp）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的载体的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物，以及包含从微球菌（Micrococcineae spp。）获得的蛋白酶的纺织和皮革加工组合物，其包括但不限于纤维单胞菌属（Cellulomonas spp） 在替代实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些突变型蛋白酶也可用于许多应用。
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