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    APPARATUS AND METHODS FOR OCCLUDING A FALLOPIAN TUBE
    2.
    发明申请
    APPARATUS AND METHODS FOR OCCLUDING A FALLOPIAN TUBE 审中-公开
    装置和方法，用于遮挡倒伏管

    公开(公告)号：WO2010005897A2

    公开(公告)日：2010-01-14

    申请号：PCT/US2009/049689

    申请日：2009-07-06

    Applicant: COHEREX MEDICAL, INC. ,  CARTER, Phillip, J. ,  LINDER, Richard, J. ,  JONES, Randall, K. ,  MILES, Scott, D. ,  DAVIS, Clark, C. ,  EDMISTON, Daryl, R. ,  FOX, Dewayne, C.

    Inventor： CARTER, Phillip, J. ,  LINDER, Richard, J. ,  JONES, Randall, K. ,  MILES, Scott, D. ,  DAVIS, Clark, C. ,  EDMISTON, Daryl, R. ,  FOX, Dewayne, C.

    IPC: A61F6/22 ,  A61B17/12

    CPC classification number: A61F6/225

    Abstract: The present invention is directed to various embodiments of medical devices and methods for occluding a fallopian tube for contraception and permanent sterilization. In one embodiment, the medical device includes an outer member, an inner member and a tissue growth member. The outer member includes an outer surface and an inner surface, wherein the inner surface defines a bore in the outer member. The inner member is configured to be positioned within the bore of the outer member. The tissue growth member is attached to the outer surface of the outer member and is configured to induce tissue growth thereto. With this arrangement, the medical device can be implanted within the fallopian tube and serve as a permanent occluding device therein. If desired, the medical device can be partially removed from the fallopian tube to restore the ability for conception.

    Abstract translation: 本发明涉及用于闭塞输卵管用于避孕和永久灭菌的医疗装置和方法的各种实施例。 在一个实施例中，医疗装置包括外部构件，内部构件和组织生长构件。 外部构件包括外表面和内表面，其中内表面在外构件中限定孔。 内部构件构造成定位在外部构件的孔内。 组织生长构件附接到外部构件的外表面并且构造成诱导组织生长。 利用这种布置，医疗装置可以植入输卵管内并用作其中的永久性闭塞装置。 如果需要，医疗设备可以部分地从输卵管中移除以恢复受孕的能力。

    MEDICAL DEVICE FOR PERCUTANEOUS PARAVALVULAR LEAK AND RELATED SYSTEMS AND METHODS
    4.
    发明申请
    MEDICAL DEVICE FOR PERCUTANEOUS PARAVALVULAR LEAK AND RELATED SYSTEMS AND METHODS 审中-公开
    用于经常性旁路淋巴结的医疗装置及相关系统和方法

    公开(公告)号：WO2009052437A1

    公开(公告)日：2009-04-23

    申请号：PCT/US2008/080380

    申请日：2008-10-17

    Applicant: COHEREX MEDICAL, INC. ,  MILES, Scott, D. ,  DAVIS, Clark, C. ,  LINDER, Richard, J.

    Inventor： MILES, Scott, D. ,  DAVIS, Clark, C. ,  LINDER, Richard, J.

    IPC: A61F2/24

    CPC classification number: A61F2/24 ,  A61F2/2409 ,  A61F2/2445 ,  A61F2250/0069

    Abstract: The present invention provides devices, systems and methods for closing a paravalvular leak. In accordance with one embodiment, a medical device includes at least one multicellular frame member (112) configured to be implanted at a paravalvular leak. The medical device further includes at least one tissue in-growth member (116) associated with the frame member, the tissue in-growth member being configured to promote tissue growth and permanently maintain the frame member at the leak. The frame member may be self expanding device formed, for example, of a shape-memory alloy. The tissue in-growth member may be formed from a polymer material. In one particular embodiment, the frame member may be a substantially tubular structure and the tissue in-growth member may be disposed within an interior space defined by the tubular structure. In another embodiment, the frame ember may be a substantially flat or planar structure.

    Abstract translation: 本发明提供了用于闭合瓣膜泄漏的装置，系统和方法。 根据一个实施例，医疗装置包括至少一个多细胞框架构件（112），其构造成以瓣间泄漏植入。 医疗装置还包括与框架构件相关联的至少一个组织生长构件（116），所述组织生长构件被构造成促进组织生长并将框架构件永久地保持在泄漏处。 框架构件可以是例如由形状记忆合金形成的自扩张装置。 组织生长部件可以由聚合物材料形成。 在一个具体实施例中，框架构件可以是基本上管状的结构，并且组织生长构件可以设置在由管状结构限定的内部空间内。 在另一个实施例中，框架余烬可以是基本平坦或平面的结构。

    OSCILLATION APPARATUS AND METHODS FOR MULTI-ANALYTE HOMOGENEOUS FLUORO-IMMUNOASSAYS
    7.
    发明申请
    OSCILLATION APPARATUS AND METHODS FOR MULTI-ANALYTE HOMOGENEOUS FLUORO-IMMUNOASSAYS 审中-公开
    多分辨荧光免疫荧光法的振荡装置及方法

    公开(公告)号：WO1997035203A1

    公开(公告)日：1997-09-25

    申请号：PCT/US1997004378

    申请日：1997-03-19

    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION ,  HERRON, James, N. ,  CHRISTENSEN, Douglas, A. ,  MILES, Scott, D.

    Inventor： UNIVERSITY OF UTAH RESEARCH FOUNDATION

    IPC: G01N33/552

    CPC classification number: G01N33/54386 ,  G01N33/54373 ,  Y10S435/808 ,  Y10S436/807

    Abstract: An apparatus and method for rapidly analyzing samples for analytes of interest by an homogeneous immunofluorescence assay. The apparatus includes a sample test cartridge having a high control sample section, a low control sample section, and at least one test sample section. Each of these sections contain at least one pre-loaded reagent housed in a well within the the cartridge wherein the low control sample section contains a known low amount of an analyte of interest and the high control sample section contains a known high amount of an analyte of interest. The cartridge includes a biosensor comprising a planar waveguide having first and second parallel plane surfaces and an edge extending between them, the edge having a receiving region for receiving a light beam. Each of the high control sample section, the low control sample section, and the test sample control sections have a well which includes a waveguide surface, wherein the contents of each section contacts capture molecules immobilized on the waveguide surface. The capture molecules are configured to specifically bind a chosen analyte and fluoresce when interacting with light passing through the waveguide surface. The concentration of said analyte of interest in said sample fluid is determined by a comparison of intensities of fluorescence of between said capture molecule areas of said sample capture molecule well, said low control capture molecule well, and said high control capture molecule well.

    Abstract translation: 用于通过均匀免疫荧光测定快速分析感兴趣的分析物的样品的装置和方法。 该装置包括具有高控制样品部分，低对照样品部分和至少一个测试样品部分的样品测试盒。 这些部分中的每一个包含至少一个预先装载的试剂，其容纳在筒内的孔中，其中低对照样品部分含有已知的低量感兴趣的分析物，并且高对照样品部分含有已知的大量分析物 出于兴趣。 所述盒包括生物传感器，所述生物传感器包括具有第一和第二平行平面的平面波导和在它们之间延伸的边缘，所述边缘具有用于接收光束的接收区域。 高控制采样部分，低控制样品部分和测试样品控制部分中的每一个具有包括波导表面的阱，其中每个部分的内容物接触固定在波导表面上的捕获分子。 捕获分子被配置为特异性地结合所选择的分析物并且当与通过波导表面的光相互作用时发出荧光。 通过比较所述样品捕获分子阱的所述捕获分子区域，所述低对照捕获分子阱和所述高对照捕获分子阱之间的荧光强度来确定所述样品流体中所述目标分析物的浓度。

    APPARATUS FOR OCCLUDING A FALLOPIAN TUBE
    8.
    发明申请
    APPARATUS FOR OCCLUDING A FALLOPIAN TUBE 审中-公开
    装置倒装管的装置

    公开(公告)号：WO2010005897A3

    公开(公告)日：2010-04-22

    申请号：PCT/US2009049689

    申请日：2009-07-06

    Applicant: COHEREX MEDICAL INC ,  CARTER PHILLIP J ,  LINDER RICHARD J ,  JONES RANDALL K ,  MILES SCOTT D ,  DAVIS CLARK C ,  EDMISTON DARYL R ,  FOX DEWAYNE C

    Inventor： CARTER PHILLIP J ,  LINDER RICHARD J ,  JONES RANDALL K ,  MILES SCOTT D ,  DAVIS CLARK C ,  EDMISTON DARYL R ,  FOX DEWAYNE C

    IPC: A61F6/22 ,  A61B17/12

    CPC classification number: A61F6/225

    Abstract: The present invention is directed to a medical device for occluding a fallopian tube for contraception and sterilization. The medical device includes an outer member (12), an inner member (14) and a tissue growth member (16). The outer member includes an outer surface (20) and an inner surface (22), wherein the inner surface defines a bore (24) in the outer member. The inner member is configured to be positioned within the bore of the outer member. The tissue growth member is attached to the outer surface of the outer member and is configured to induce tissue growth thereto. With this arrangement, the medical device can be implanted within the fallopian tube and serve as an occluding device therein. If desired, the medical device can be partially removed from the fallopian tube to restore the ability for conception.

    Abstract translation: 本发明涉及一种用于闭塞输卵管用于避孕和灭菌的医疗装置。 医疗装置包括外部构件（12），内部构件（14）和组织生长构件（16）。 外部构件包括外表面（20）和内表面（22），其中内表面在外部构件中限定孔（24）。 内部构件构造成定位在外部构件的孔内。 组织生长构件附接到外部构件的外表面并且构造成诱导组织生长。 通过这种布置，医疗装置可以植入输卵管内并用作其中的闭塞装置。 如果需要，医疗设备可以部分地从输卵管中移除以恢复受孕的能力。

    VENTRICULAR ASSIST DEVICE AND RELATED METHODS
    9.
    发明申请
    VENTRICULAR ASSIST DEVICE AND RELATED METHODS 审中-公开
    静脉辅助装置及相关方法

    公开(公告)号：WO2009137530A3

    公开(公告)日：2010-04-22

    申请号：PCT/US2009042910

    申请日：2009-05-05

    Applicant: COHEREX MEDICAL INC ,  WHISENANT BRIAN K ,  MILES SCOTT D

    Inventor： WHISENANT BRIAN K ,  MILES SCOTT D

    IPC: A61M1/36

    CPC classification number: A61F2/06 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/3425 ,  A61B2017/3484 ,  A61B2017/3488 ,  A61F2/064 ,  A61M27/002

    Abstract: A method and system are provided for percutaneously gaining access to oxygenated blood with an anastomosis device and pumping such oxygenated blood to other arterial regions of the vascular system via an LVAD system. In one embodiment, a system may include an anastomosis device extending through an opening of the atrial septum. A filament may be coupled to the anastomosis device. A snare device may access the right atrium through the superior vena cava, grasp the filament, and withdraw the filament through the superior vena cava. The filament may then be used as a guide to direct a catheter, a conduit or some other structure into the right atrium of the heart via the superior vena cava. A flow path may be defined between the anastomosis device and an arterial location, such as in the aorta, such that at least some oxygenated blood may by-pass the left ventricle and be discharged into the aorta.

    Abstract translation: 提供了一种方法和系统，用于通过吻合装置经皮获得含氧血液，并经由LVAD系统将这种氧合血液泵送到血管系统的其他动脉区域。 在一个实施例中，系统可以包括延伸穿过心房隔膜的开口的吻合装置。 丝可以连接到吻合装置。 圈套装置可以通过上腔静脉进入右心房，抓住细丝，并通过上腔静脉取出细丝。 然后可以将细丝用作引导件，以将导管，导管或一些其它结构经由上腔静脉引导到心脏的右心房。 可以在吻合装置和动脉位置（例如主动脉）之间限定流动路径，使得至少一些氧合血液可以绕过左心室并排出到主动脉。

    VENTRICULAR ASSIST DEVICE AND RELATED METHODS
    10.
    发明申请
    VENTRICULAR ASSIST DEVICE AND RELATED METHODS 审中-公开
    静脉辅助装置及相关方法

    公开(公告)号：WO2009137530A2

    公开(公告)日：2009-11-12

    申请号：PCT/US2009/042910

    申请日：2009-05-05

    Applicant: COHEREX MEDICAL, INC. ,  MILES, Scott, D. ,  WHISENANT, Brian, K.

    Inventor： MILES, Scott, D. ,  WHISENANT, Brian, K.

    IPC: A61M1/10

    CPC classification number: A61F2/06 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/3425 ,  A61B2017/3484 ,  A61B2017/3488 ,  A61F2/064 ,  A61M27/002

    Abstract: A method and system are provided for percutaneously gaining access to oxygenated blood with an anastomosis device and pumping such oxygenated blood to other arterial regions of the vascular system via an LVAD system. In one embodiment, a system may include an anastomosis device extending through an opening of the atrial septum. A filament may be coupled to the anastomosis device. A snare device may access the right atrium through the superior vena cava, grasp the filament, and withdraw the filament through the superior vena cava. The filament may then be used as a guide to direct a catheter, a conduit or some other structure into the right atrium of the heart via the superior vena cava. A flow path may be defined between the anastomosis device and an arterial location, such as in the aorta, such that at least some oxygenated blood may by-pass the left ventricle and be discharged into the aorta.

    Abstract translation: 提供了一种方法和系统，用于通过吻合装置经皮获得含氧血液，并经由LVAD系统将这种氧合血液泵送到血管系统的其他动脉区域。 在一个实施例中，系统可以包括延伸穿过心房隔膜的开口的吻合装置。 丝可以连接到吻合装置。 圈套装置可以通过上腔静脉进入右心房，抓住细丝，并通过上腔静脉取出细丝。 然后可以将细丝用作引导件，以将导管，导管或一些其它结构经由上腔静脉引导到心脏的右心房。 可以在吻合装置和动脉位置（例如主动脉）之间限定流动路径，使得至少一些含氧血液可以绕过左心室并排出到主动脉。

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