NANO-DEVICES IN DETECTION AND TREATMENT OF CANCER

    公开(公告)号:WO2018091884A1

    公开(公告)日:2018-05-24

    申请号:PCT/GB2017/053431

    申请日:2017-11-15

    Inventor: NAASANI, Imad

    Abstract: Compositions and methods are described for detecting and treating conditions including cancer with target specific quantum dot nano-devices. In some aspects, nanoparticle conjugates are provided having multiple target specificities and include surface modified, water soluble quantum dot (QD) nanoparticles each of which are chemically conjugated to at least two different target specific ligands.

    EXOSOME-CONJUGATED QUANTUM DOT NANOPARTICLES AND METHODS OF DETECTING EXOSOMES AND CANCER USING SAME
    3.
    发明申请
    EXOSOME-CONJUGATED QUANTUM DOT NANOPARTICLES AND METHODS OF DETECTING EXOSOMES AND CANCER USING SAME 审中-公开
    外共轭量子点纳米颗粒和使用相同方法检测外来体和癌症的方法

    公开(公告)号:WO2018046879A1

    公开(公告)日:2018-03-15

    申请号:PCT/GB2017/000129

    申请日:2017-09-06

    Inventor: NAASANI, Imad

    Abstract: The present disclosure relates to a plurality of quantum dot nanoparticles conjugated to ligands, and in particular a plurality of quantum dot nanoparticles wherein each nanoparticle is conjugated to an exosome-specific binding ligand. The present disclosure also relates to methods of making such a plurality of conjugated quantum dot nanoparticles, methods of detecting exosomes using such a plurality of conjugated quantum dot nanoparticles and methods of detecting exosomes using such a plurality of conjugated quantum dot nanoparticles.

    Abstract translation: 本公开涉及与配体缀合的多个量子点纳米粒子,特别是多个量子点纳米粒子,其中每个纳米粒子与外来体特异性结合配体缀合。 本发明还涉及制造这种多个共轭量子点纳米颗粒的方法,使用这种多个共轭量子点纳米颗粒来检测外来体的方法以及使用这种多个共轭量子点纳米颗粒来检测外来体的方法。

    FORMATION OF 2D FLAKES FROM CHEMICAL CUTTING OF PREFABRICATED NANOPARTICLES AND VAN DER WAALS HETEROSTRUCTURE DEVICES MADE USING THE SAME
    4.
    发明申请
    FORMATION OF 2D FLAKES FROM CHEMICAL CUTTING OF PREFABRICATED NANOPARTICLES AND VAN DER WAALS HETEROSTRUCTURE DEVICES MADE USING THE SAME 审中-公开
    由预制纳米颗粒化学切割形成2D薄片以及使用相同方法制造的范德华异构结构器件

    公开(公告)号:WO2018002607A2

    公开(公告)日:2018-01-04

    申请号:PCT/GB2017/051877

    申请日:2017-06-28

    Abstract: A method of synthesis of two-dimensional (2D) nanoflakes comprises the cutting of prefabricated nanoparticles. The method allows high control over the shape, size and composition of the 2D nanoflakes, and can be used to produce material with uniform properties in large quantities. Van der Waals heterostructure devices are prepared by fabricating nanoparticles, chemically cutting the nanoparticles to form nanoflakes, dispersing the nanoflakes in a solvent to form an ink, and depositing the ink to form a thin film.

    Abstract translation: 合成二维(2D)纳米薄片的方法包括切割预制纳米颗粒。 该方法可以高度控制二维纳米薄片的形状,大小和成分,并可用于大量生产具有统一性能的材料。 范德华异质结构装置通过制造纳米颗粒,化学切割纳米颗粒以形成纳米薄片,将纳米薄片分散在溶剂中以形成油墨,以及沉积油墨以形成薄膜而制备。

    PHOTOVOLTAIC DEVICE WITH GRADED GRAIN SIZE AND S:SE RATIO
    8.
    发明申请
    PHOTOVOLTAIC DEVICE WITH GRADED GRAIN SIZE AND S:SE RATIO 审中-公开
    具有格子尺寸和S:SE比例的光伏器件

    公开(公告)号:WO2014140897A3

    公开(公告)日:2014-12-04

    申请号:PCT/IB2014001132

    申请日:2014-03-14

    Abstract: Disclosed herein are CIGS-based photon-absorbing layers disposed on a substrate. The photon-absorbing layers are useful in photovoltaic devices. The photon absorbing-layer is made of a semiconductor material having empirical formula AB1-xB'xC2-yC'y, where A is Cu, Zn, Ag or Cd; B and B' are independently A1, In or Ga; C and C' are independently S, or Se, and wherein 0 ≤ x ≤ 1; and 0 ≤ y ≤ 2. The grain size of the semiconductor material and the composition of the semiconductor material both vary as a function of depth across the layer. The layers described herein exhibit improved photovoltaic properties, including increased shunt resistance and decreased backside charge carrier recombination.

    Abstract translation: 本文公开了设置在基板上的基于CIGS的光子吸收层。 光子吸收层可用于光伏器件。 光子吸收层由具有经验式AB1-xB'xC2-yC'y的半导体材料制成,其中A是Cu,Zn,Ag或Cd; B和B'独立地为Al,In或Ga; C和C'独立地为S或Se,并且其中0≤x≤1; 并且0≤y≤2。半导体材料的晶粒尺寸和半导体材料的组成都随着层的深度而变化。 本文描述的层表现出改进的光伏特性,包括增加的分流电阻和减小的背侧电荷载流子复合。

    QUANTUM DOT LIGHT-EMITTING DIODES FOR PHOTOTHERAPY
    9.
    发明申请
    QUANTUM DOT LIGHT-EMITTING DIODES FOR PHOTOTHERAPY 审中-公开
    量子点光发光二极管用于摄影

    公开(公告)号:WO2014177943A2

    公开(公告)日:2014-11-06

    申请号:PCT/IB2014001591

    申请日:2014-03-14

    Abstract: Disclosed herein are articles for use in phototherapy utilizing quantum dots (QDs). One embodiment is a medical dressing having an occlusive layer and translucent layer. Quantum dot light-emitting diode chips are configured within the occlusive layer to provide light of a specific wavelength for use in phototherapy. Another embodiment is a medical dressing having an occlusive layer and translucent layer, wherein quantum dot material is embedded or impregnated within one or both layers.

    Abstract translation: 本文公开了用于使用量子点(QD)的光疗法的制品。 一个实施方案是具有闭塞层和半透明层的医用敷料。 量子点发光二极管芯片被配置在闭塞层内以提供用于光疗的特定波长的光。 另一个实施方案是具有闭塞层和半透明层的医用敷料,其中量子点材料嵌入或浸渍在一层或两层中。

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