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    MEASURING OUTLFLOW RESISTANCE/FACILITY OF AN EYE
    1.
    发明申请
    MEASURING OUTLFLOW RESISTANCE/FACILITY OF AN EYE 审中-公开
    测量眼睛的流失电阻/设备

    公开(公告)号：WO2009111726A3

    公开(公告)日：2010-01-07

    申请号：PCT/US2009036378

    申请日：2009-03-06

    申请人： UNIV CALIFORNIA ,  PAN TINGRUI ,  BRANDT JAMES DAVID

    发明人： PAN TINGRUI ,  BRANDT JAMES DAVID

    IPC分类号： A61B3/16

    CPC分类号： A61B3/16

    摘要： A measurement system takes measurements of intraocular pressure and displaced ocular volume for determination of aqueous outflow resistance A device with a pgid outer wall, a flexible inner wall, and an inflatable bladder in between is placed over the eye A pressure measurement system is coupled to the bladder and is configured to measure a pressure of fluid within the bladder A hydraulic unit is coupled to the bladder and configured to control a flow of fluid between the bladder and an external reservoir, and to measure a change of volume in the bladder created by the pressure applied to the eye Both the pressure measurement system and hydraulic unit are directly controlled by and communicated with a microprocessor/computer In addition, the microprocessor computes the outflow resistance of the eye as a function of the pressure in the bladder and the change of volume in the bladder over time.

    摘要翻译： 测量系统测量眼内压和取代的眼睛体积以确定水流出阻力在眼睛之上放置具有pgid外壁，柔性内壁和可膨胀囊的装置。压力测量系统耦合到 气囊，并且被配置成测量囊内的流体的压力。液压单元联接到气囊并且构造成控制气囊和外部储液器之间的流体流动，并且测量膀胱和外部储液器中产生的膀胱中的体积变化 施加到眼睛上的压力压力测量系统和液压单元由微处理器/计算机直接控制并与之通信另外，微处理器根据膀胱压力和体积变化来计算眼睛的流出阻力 随着时间的流逝。

    BYPASS FOR GLAUCOMA DRAINAGE DEVICE
    2.
    发明申请
    BYPASS FOR GLAUCOMA DRAINAGE DEVICE 审中-公开
    GLAUCOMA排水装置旁路

    公开(公告)号：WO2004073564A2

    公开(公告)日：2004-09-02

    申请号：PCT/US2004004073

    申请日：2004-02-12

    申请人： UNIV MINNESOTA ,  BROWN J DAVID ,  PAN TINGRUI ,  ZIAIE BABAK

    发明人： BROWN J DAVID ,  PAN TINGRUI ,  ZIAIE BABAK

    IPC分类号： A61F9/007 ,  A61M5/14 ,  A61M27/00 ,  A61M39/00 ,  A61M39/22 ,  F16K47/00 ,  F16K47/04

    CPC分类号： A61M27/002 ,  A61F9/00781 ,  A61M5/141

    摘要： Aqueous humor flow control for managing intraocular pressure in an eye. Excessive pressure due to formation of a fibrous capsule and valve resistance is relieved by bypassing the valve element or by providing a secondary discharge port. Removal of resistance is enabled by physical manipulation, external stimulus, chemical action or biological action. A resistor inserted in an intake conduit provides a predetermined resistance to flow and thus, a desired intraocular pressure.

    摘要翻译： 用于管理眼中眼内压的水性幽默流量控制。 由于形成纤维胶囊而导致的过大压力和阀门阻力通过绕过阀元件或通过提供二次排出口来释放。 通过物理操纵，外部刺激，化学作用或生物作用可以消除抵抗力。 插入进气管道中的电阻器提供预定的流动阻力，从而提供所需的眼内压。

    MEASURING OUTLFLOW RESISTANCE/FACILITY OF AN EYE
    3.
    发明申请
    MEASURING OUTLFLOW RESISTANCE/FACILITY OF AN EYE 审中-公开
    测量眼睛的流失电阻/设备

    公开(公告)号：WO2009111726A2

    公开(公告)日：2009-09-11

    申请号：PCT/US2009/036378

    申请日：2009-03-06

    申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  PAN, Tingrui ,  BRANDT, James, David

    发明人： PAN, Tingrui ,  BRANDT, James, David

    IPC分类号： A61B3/16

    CPC分类号： A61B3/16

    摘要： A dual-measurement system/method takes real-time, direct manipulation and measurements of intraocular pressure and displaced ocular volume for determination of aqueous outflow resistance/facility. A contact-lens device with a rigid outer wall, a flexible inner wall, and an inflatable bladder in between is placed over the eye so the flexible inner wall contacts the eye. A pressure measurement system (e.g., pressure sensors embedded in the flexible inner wall, or pressure sensors hydraulic connected to the bladder) is coupled to the bladder and is configured to measure a pressure of fluid within the bladder. A hydraulic unit is also coupled to the bladder and configured to control a flow of fluid between the bladder and an external reservoir, and to also measure a change of volume in the bladder created by the pressure applied to the eye. Both the pressure measurement system and hydraulic unit are directly controlled by and communicated with a microprocessor/computer. In addition, the microprocessor/computer computes the outflow resistance/facility of the eye as a function of the pressure in the bladder and the change of volume in the bladder over time.

    摘要翻译： 双重测量系统/方法需要实时，直接操作和测量眼内压和排除的眼部体积，以确定水流出阻力/设施。 具有刚性外壁，柔性内壁和中间的可充气囊的隐形眼镜装置放置在眼睛上方，使得柔性内壁接触眼睛。 压力测量系统（例如，嵌入在柔性内壁中的压力传感器或液压连接到气囊的压力传感器）联接到气囊并且被配置成测量膀胱内的流体的压力。 液压单元还联接到气囊并且被配置为控制气囊和外部容器之间的流体流动，并且还测量由施加到眼睛的压力产生的膀胱中的体积变化。 压力测量系统和液压单元都由微处理器/计算机直接控制和连接。 此外，微处理器/计算机根据膀胱中的压力和膀胱中的体积随时间的变化来计算眼睛的流出阻力/设施。

    UNIVERSAL NANOPATTERNABLE INTERFACIAL BONDING
    4.
    发明申请
    UNIVERSAL NANOPATTERNABLE INTERFACIAL BONDING 审中-公开

    公开(公告)号：WO2013059762A8

    公开(公告)日：2013-04-25

    申请号：PCT/US2012/061240

    申请日：2012-10-21

    申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  PAN, Tingrui ,  DING, Yuzhe ,  GARLAND, Shaun P. ,  MENG, Yuan

    发明人： PAN, Tingrui ,  DING, Yuzhe ,  GARLAND, Shaun P. ,  MENG, Yuan

    IPC分类号： C09J5/00 ,  C09J5/02 ,  C09J5/04 ,  C09J4/00 ,  C09J9/02

    摘要： One embodiment of the present invention provides a system for bonding a first substrate and a second substrate. During operation, the system starts by treating a first surface of the first substrate and a second surface of the second substrate with a hydrophilic treatment. The system then transfers a first oligomer layer onto the treated first surface and a second oligomer layer onto the treated second surface. Next, the system treats the first oligomer layer and the second oligomer layer for hydrophilic activation. The system subsequently brings the first oligomer layer into contact with the second oligomer layer, thereby allowing the two oligomer layers to adhere and form a single bonding layer between the first substrate and the second substrate. In particular, each of the first oligomer layer and the second oligomer layer is a polydimethylsiloxane (PDMS) layer.