公开(公告)号：WO2011015453A8

公开(公告)日：2011-03-31

申请号：PCT/EP2010060557

申请日：2010-07-21

Applicant: IMA LIFE SRL ,  VAN VEEN JOHANNES ,  DAMEN FRANCISCUS ANTONIUS ,  SCHAEPMAN ALEXANDER CLEMENS HENRICUS JOSEF ,  JONGENELEN FLORENTINUS ADRIAAN CORNELIS MARIE

Inventor： VAN VEEN JOHANNES ,  DAMEN FRANCISCUS ANTONIUS ,  SCHAEPMAN ALEXANDER CLEMENS HENRICUS JOSEF ,  JONGENELEN FLORENTINUS ADRIAAN CORNELIS MARIE

IPC: F26B5/06 ,  F26B25/00

CPC classification number: F26B5/06 ,  B65G47/82 ,  F26B25/001

Abstract: Method for transfer of containers, such as vials (101), between a freeze dryer (1) that is located at a first location and a separate transport vehicle (30) that is mobile with respect to the freeze dryer, wherein the freeze dryer (1) comprises a freeze dryer housing (2) with an access opening (11) towards an inner freeze drying chamber (10) inside the freeze dryer housing (2), multiple shelves (21-24) that are arranged spaced apart above each other inside the freeze dryer chamber (10) and each provided with a horizontally extending first flat supporting surface (25) for supporting the containers, wherein the mobile transport vehicle (30) comprises a mobile undercarriage (31) supporting a storage housing (33) with an access opening (40) towards an inner storage chamber (39), a carrier provided with a second flat supporting surface (58) for supporting the containers inside the storage housing (33), and a container shifter (60) for pushing out containers away from the second flat supporting surface (58) in a pushing out direction parallel to the second flat supporting surface (58).

Abstract translation: 在位于第一位置的冷冻干燥器（1）和可相对于冷冻干燥器移动的单独的运输车辆（30）之间转运诸如小瓶（101）的容器的方法，其中所述冷冻干燥器 冷冻干燥器壳体（2）包括在冷冻干燥器壳体（2）内部具有朝向内部冷冻干燥室（10）的进入开口（11）的冷冻干燥器壳体，彼此间隔开地布置的多个搁架（21-24） 在所述冷冻干燥器室（10）内部并且每个设置有用于支撑所述容器的水平延伸的第一平坦支撑表面（25），其中所述移动式运输车辆（30）包括支撑储存壳体（33）的移动式起落架（31） 朝向内部存储室（39）的进入开口（40），设置有用于将容器支撑在储存壳体（33）内的第二扁平支撑表面（58）的托架和用于推出容器的容器移位器（60） 远离第二个平面支撑 （58）在平行于第二平坦支撑表面（58）的推出方向上。

公开(公告)号：WO2009050177A1

公开(公告)日：2009-04-23

申请号：PCT/EP2008/063832

申请日：2008-10-15

Applicant: IMA LIFE S.R.L. ,  SCHAEPMAN, Alexander Clemens Henricus Josef ,  CORVER, Jozef Antonius Willem Maria ,  BONS, Vincent Alexander

Inventor： SCHAEPMAN, Alexander Clemens Henricus Josef ,  CORVER, Jozef Antonius Willem Maria ,  BONS, Vincent Alexander

IPC: G01N21/25 ,  G01N21/35 ,  G01N21/90

CPC classification number: G01N21/3554 ,  G01N21/9027 ,  G01N21/94

Abstract: The disclosure provides for a system and method of characterizing or inspecting the content of moving containers with Infrared IR spectroscopy from the side. Data processing techniques are used to eliminate effects of variable path lengths and light scattering in such way that the resulting spectra are comparable with a spectra acquired from static containers.

Abstract translation: 本公开提供了从侧面用红外线红外光谱表征或检查移动容器的内容物的系统和方法。 数据处理技术用于消除可变路径长度和光散射的影响，使得所得到的光谱与从静态容器获得的光谱相当。

公开(公告)号：WO2013182870A1

公开(公告)日：2013-12-12

申请号：PCT/IB2012/052804

申请日：2012-06-04

Applicant: GEA PROCESS ENGINEERING NV ,  VERHOEST, Bart, Peter ,  SCHAEPMAN, Alexander, Clemens, Henricus, Josef ,  VUGTS, Johannes, Adrianus, Jozef, Maria

Inventor： VERHOEST, Bart, Peter ,  SCHAEPMAN, Alexander, Clemens, Henricus, Josef ,  VUGTS, Johannes, Adrianus, Jozef, Maria

IPC: G01G19/393 ,  B01F15/04 ,  G01G19/32

CPC classification number: B01F13/1058 ,  B01F3/18 ,  B01F15/0251 ,  B01F15/0445 ,  G01G19/32 ,  G01G19/393

Abstract: The feeder module comprises a number, for instance five to eight, feeder units. Each feeder unit includes a storage hopper, a weighing cell, a conveyer, and a discharge end. The feeder units may be arranged in a single level and in a spokes-like configuration,in which each feeder unit extends radially outwards from an imaginary inner circle defined at the discharge end adapted to face the common receiving container to an imaginary outer circle defined by radially opposite end of each feeder unit, the feeder units being positioned substantially on radii extending from the inner circle. The feeder module makes it possible to provide a very accurately dosed mixture of one or more powders to a receiving container.

Abstract translation: 给料器模块包括数量，例如五到八个进料器单元。 每个进料器单元包括存储料斗，称重单元，输送机和排出端。 馈送单元可以布置在单个级别和轮辐状构造中，其中每个馈送单元从限定在适于面对公共接收容器的排出端处的假想内圆径向向外延伸到由 每个供给单元的径向相对端，馈送单元基本上位于从内圆延伸的半径上。 给料器模块使得可以将一种或多种粉末的非常准确的剂量混合物提供给接收容器。

公开(公告)号：WO2013182869A1

公开(公告)日：2013-12-12

申请号：PCT/IB2012/052803

申请日：2012-06-04

Applicant: GEA PROCESS ENGINEERING NV ,  VERHOEST, Bart ,  SCHAEPMAN, Alexander, Clemens, Henricus, Josef ,  VUGTS, Johannes, Adrianus, Jozef, Maria

Inventor： VERHOEST, Bart ,  SCHAEPMAN, Alexander, Clemens, Henricus, Josef ,  VUGTS, Johannes, Adrianus, Jozef, Maria

IPC: G01G13/00 ,  G01G11/08 ,  G01G17/00

CPC classification number: B65B1/04 ,  B65B1/32 ,  G01G11/08 ,  G01G13/006 ,  G01G17/00

Abstract: A feeder unit (2) comprising a storage hopper (21), a weighing cell (24), a conveyer (22), and a discharge end (23), wherein the storage hopper is adapted to be connected to a refilling system, and the discharge end (23) to a receiving container. A working space (ws) is defined by the aritmethic product of the dead weight (dw) of the feeder unit (2) and the refilling interval (ri), such that the working space (ws) is below 0.2 kgh. Furthermore a method method for discharging a constant mass flow of one or more powders into a receiving container is defined.

Abstract translation: 一种包括存储料斗（21），称重传感器（24），输送机（22）和排出端（23）的进料器单元（2），其中储存料斗适于连接到再填充系统，以及 排出端（23）到接收容器。 工作空间（ws）由进料器单元（2）的自重（dw）和再填充间隔（ri）的代数乘积定义，使得工作空间（ws）低于0.2kgh。 此外，定义了将一种或多种粉末的恒定质量流量排放到接收容器中的方法。

公开(公告)号：WO2011015453A1

公开(公告)日：2011-02-10

申请号：PCT/EP2010/060557

申请日：2010-07-21

Applicant: IMA LIFE S.R.L. ,  VAN VEEN, Johannes ,  DAMEN, Franciscus Antonius ,  SCHAEPMAN, Alexander Clemens Henricus Josef ,  JONGENELEN, Florentinus Adriaan Cornelius Marie

Inventor： VAN VEEN, Johannes ,  DAMEN, Franciscus Antonius ,  SCHAEPMAN, Alexander Clemens Henricus Josef ,  JONGENELEN, Florentinus Adriaan Cornelius Marie

IPC: F26B5/06 ,  F26B25/00

CPC classification number: F26B5/06 ,  B65G47/82 ,  F26B25/001

Abstract: Method for transfer of containers, such as vials (101), between a freeze dryer (1) that is located at a first location and a separate transport vehicle (30) that is mobile with respect to the freeze dryer, wherein the freeze dryer (1) comprises a freeze dryer housing (2) with an access opening (11) towards an inner freeze drying chamber (10) inside the freeze dryer housing (2), multiple shelves (21-24) that are arranged spaced apart above each other inside the freeze dryer chamber (10) and each provided with a horizontally extending first flat supporting surface (25) for supporting the containers, wherein the mobile transport vehicle (30) comprises a mobile undercarriage (31) supporting a storage housing (33) with an access opening (40) towards an inner storage chamber (39), a carrier provided with a second flat supporting surface (58) for supporting the containers inside the storage housing (33), and a container shifter (60) for pushing out containers away from the second flat supporting surface (58) in a pushing out direction parallel to the second flat supporting surface (58).

Abstract translation: 用于在位于第一位置的冷冻干燥机（1）和可相对于第一位置移动的单独运输车辆（30）之间传送诸如小瓶（101）的容器的方法， 其中所述冷冻干燥机（1）包括具有朝向所述冷冻干燥机壳体（2）内的内部冷冻干燥室（10）的进入开口（11）的冷冻干燥机壳体（2），多个搁架（21-24） （30）包括移动式底架（31），所述移动式底架在所述冷冻干燥器室（10）内彼此间隔开地布置并且各自设置有用于支撑所述容器的水平延伸的第一平坦支撑表面（25），其中所述移动式运输车辆 支撑具有朝向内部存储室（39）的进入开口（40）的存储壳体（33），设置有用于支撑存储壳体（33）内的容器的第二平坦支撑表面（58）的载体，以及容器 （60），用于将容器从第二端推出 d平坦支撑表面（58）沿平行于第二平坦支撑表面（58）的推出方向移动。

公开(公告)号：WO2009030760A1

公开(公告)日：2009-03-12

申请号：PCT/EP2008/061802

申请日：2008-09-05

Applicant: IMA LIFE S.R.L. ,  KEMMEREN, Antonius Lucien Adrianus Maria ,  BONS, Vincent Alexander ,  VAN VEEN, Johannes ,  SCHAEPMAN, Alexander Clemens Henricus Josef ,  CORVER, Jozef Antonius Willem Maria

Inventor： KEMMEREN, Antonius Lucien Adrianus Maria ,  BONS, Vincent Alexander ,  VAN VEEN, Johannes ,  SCHAEPMAN, Alexander Clemens Henricus Josef ,  CORVER, Jozef Antonius Willem Maria

IPC: F26B5/06

CPC classification number: F26B5/06

Abstract: Device for treatment of materials by freeze drying, comprising a housing (2) having first walls (9,15) that define a drying chamber (3) that is equipped for the accommodation of the material for drying and destined for carrying out the freeze drying process, and a controller assembly (40) for the evaluation of process parameters during the freeze drying process, wherein the controller assembly comprises a controller antenna (41) for high frequency electromagnetic wireless communication with measuring transponders (23) arranged within the drying chamber (3), which controller antenna (41) is placed outside the drying chamber (3).

Abstract translation: 用于通过冷冻干燥处理材料的装置，包括具有限定干燥室（3）的第一壁（9,15）的壳体（2），所述第一壁限定干燥室（3），所述干燥室用于容纳所述干燥材料，并用于进行冷冻干燥 过程和用于在冷冻干燥过程期间评估过程参数的控制器组件（40），其中控制器组件包括用于与设置在干燥室内的测量应答器（23）进行高频电磁无线通信的控制器天线（41） 3），该控制器天线（41）放置在干燥室（3）的外部。

公开(公告)号：WO2006114588A2

公开(公告)日：2006-11-02

申请号：PCT/GB2006/001471

申请日：2006-04-21

Applicant: THE BOC GROUP PLC ,  BONS, Vincent, Alexander ,  SCHAEPMAN, Alexander, Clemens, Henricus, Josef ,  KRIECKAART, Josefhus, Francisca, Eduardus, Maria ,  CORVER, Jozef, Antonius, Willem, Maria

Inventor： BONS, Vincent, Alexander ,  SCHAEPMAN, Alexander, Clemens, Henricus, Josef ,  KRIECKAART, Josefhus, Francisca, Eduardus, Maria ,  CORVER, Jozef, Antonius, Willem, Maria

IPC: G01R33/44

CPC classification number: G01N24/085

Abstract: A method of determining the mass of a moving sample is described, in which the sample is moved at a controlled velocity through a mass interrogation zone and a temperature interrogation zone, which may be upstream or downstream from the mass interrogation zone. Using a magnetic resonance method, a first signal is generated as the sample passes through the mass interrogation zone, the first signal having a characteristic that varies with the mass of the sample and with the temperature of the sample. A beam of electromagnetic radiation of a terahertz frequency or a near-infrared wavelength is generated and directed through the temperature interrogation zone. As the sample moves through the temperature interrogation zone, the electromagnetic radiation reflected from or transmitted through the sample is detected, and from that detected electromagnetic radiation a second signal is generated that has a characteristic that varies with the temperature of the sample. The characteristic of the first signal is adjusted using the second signal to produce a temperature compensated characteristic, which is compared to a similar characteristic obtained from a similar sample of known mass to determine the mass of the sample.

Abstract translation: 描述了确定移动样品的质量的方法，其中样品以受控的速度通过质量询问区和温度询问区移动，该质询讯问区和温度询问区可以在质询问区的上游或下游。 使用磁共振方法，当样品通过质量询问区时，产生第一信号，第一信号具有随样品质量和样品温度而变化的特性。 产生太赫兹频率或近红外波长的电磁辐射束并引导通过温度询问区。 当样品移动通过温度询问区时，检测从样品反射或透过样品的电磁辐射，并从该检测到的电磁辐射中产生具有随试样温度变化的特性的第二信号。 使用第二信号调整第一信号的特性以产生温度补偿特性，其与从已知质量的相似样品获得的类似特性进行比较，以确定样品的质量。