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公开(公告)号：WO2009029587A3
公开(公告)日：2009-03-05
申请号：PCT/US2008/074242
申请日：2008-08-25
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN , SWAROOP, Anand , ABECASIS, Goncalo , KANDA, Atsuhiro
Inventor： SWAROOP, Anand , ABECASIS, Goncalo , KANDA, Atsuhiro
IPC: C12Q1/68
Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers (e.g., polymorphisms and/or haplotypes) for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
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Patent Agency Ranking
公开(公告)号：WO2008045952A3
公开(公告)日：2009-04-30
申请号：PCT/US2007080975
申请日：2007-10-10
Applicant: UNIV MICHIGAN , SWAROOP ANAND , AKIMOTO MASAYUKI , MEARS ALAN , CHENG HONG , OH EDWIN C T
Inventor： SWAROOP ANAND , AKIMOTO MASAYUKI , MEARS ALAN , CHENG HONG , OH EDWIN C T
IPC: C12N5/00 , A01K67/00 , A01K67/027 , C12N5/0793 , C12N5/18 , G01N33/00
CPC classification number: C12N5/062 , A01K67/0275 , A01K2217/05 , A01K2227/105 , A01K2267/03 , A61K35/44 , C12N15/8509 , C12N2501/385 , C12N2830/008
Abstract: The present invention relates to photoreceptor cells. In particular, the present invention provides photoreceptor cells comprising heterologous nucleic acid sequences and transgenic animals comprising the same. The present invention also provides photoreceptor precursor cells (e.g., rod photoreceptor precursor cells), and methods of identifying, characterizing, isolating and utilizing the same. Compositions and methods of the present invention find use in, among other things, research, clinical, diagnostic, drug discovery, and therapeutic applications.
Abstract translation: 本发明涉及感光细胞。 特别地，本发明提供包含异源核酸序列的感光细胞和包含其的转基因动物。 本发明还提供感光体前体细胞（例如，棒状感光体前体细胞），以及识别，表征，分离和利用该感光体前体细胞的方法。 本发明的组合物和方法尤其可用于研究，临床，诊断，药物发现和治疗应用。
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3.发明申请
公开(公告)号：WO2011006161A3
公开(公告)日：2011-06-16
申请号：PCT/US2010041720
申请日：2010-07-12
Applicant: UNIV MICHIGAN , MAYO FOUNDATION , UNIV PENNSYLVANIA , SWAROOP ANAND , ABECASIS GONCALO , CHEN WEI , EDWARDS ALBERT O , STAMBOLIAN DWIGHT
Inventor： SWAROOP ANAND , ABECASIS GONCALO , CHEN WEI , EDWARDS ALBERT O , STAMBOLIAN DWIGHT
CPC classification number: C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , Y10T436/143333
Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
Abstract translation: 本发明一般涉及用于黄斑变性的生物标志物。 特别地，本发明提供了多个用于监测和诊断黄斑变性的生物标志物。 本发明的组合物和方法可用于诊断，治疗，研究和药物筛选应用。
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4.发明申请
公开(公告)号：WO2011006161A2
公开(公告)日：2011-01-13
申请号：PCT/US2010/041720
申请日：2010-07-12
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN , MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA , SWAROOP, Anand , ABECASIS, Gonçalo , CHEN, Wei , EDWARDS, Albert, O. , STAMBOLIAN, Dwight
Inventor： SWAROOP, Anand , ABECASIS, Gonçalo , CHEN, Wei , EDWARDS, Albert, O. , STAMBOLIAN, Dwight
CPC classification number: C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , Y10T436/143333
Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
Abstract translation: 本发明一般涉及黄斑变性的生物标志物。 特别地，本发明提供了用于监测和诊断黄斑变性的多种生物标志物。 本发明的组合物和方法可用于诊断，治疗，研究和药物筛选应用。
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5.发明申请
公开(公告)号：WO2009029587A2
公开(公告)日：2009-03-05
申请号：PCT/US2008074242
申请日：2008-08-25
Applicant: UNIV MICHIGAN , SWAROOP ANAND , ABECASIS GONCALO , KANDA ATSUHIRO
Inventor： SWAROOP ANAND , ABECASIS GONCALO , KANDA ATSUHIRO
IPC: C12Q1/68
CPC classification number: C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers (e.g., polymorphisms and/or haplotypes) for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
Abstract translation: 本发明一般涉及用于黄斑变性的生物标志物。 特别地，本发明提供了多个用于监测和诊断黄斑变性的生物标志物（例如，多态性和/或单体型）。 本发明的组合物和方法可用于诊断，治疗，研究和药物筛选应用。
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公开(公告)号：WO2008045952A2
公开(公告)日：2008-04-17
申请号：PCT/US2007/080975
申请日：2007-10-10
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN , SWAROOP, Anand , AKIMOTO, Masayuki , MEARS, Alan , CHENG, Hong , OH, Edwin, C.t.
Inventor： SWAROOP, Anand , AKIMOTO, Masayuki , MEARS, Alan , CHENG, Hong , OH, Edwin, C.t.
IPC: C12N5/06
CPC classification number: C12N5/062 , A01K67/0275 , A01K2217/05 , A01K2227/105 , A01K2267/03 , A61K35/44 , C12N15/8509 , C12N2501/385 , C12N2830/008
Abstract: The present invention relates to photoreceptor cells. In particular, the present invention provides photoreceptor cells comprising heterologous nucleic acid sequences and transgenic animals comprising the same. The present invention also provides photoreceptor precursor cells (e.g., rod photoreceptor precursor cells), and methods of identifying, characterizing, isolating and utilizing the same. Compositions and methods of the present invention find use in, among other things, research, clinical, diagnostic, drug discovery, and therapeutic applications.
Abstract translation: 本发明涉及感光细胞。 特别地，本发明提供包含异源核酸序列的感光细胞和包含其的转基因动物。 本发明还提供感光体前体细胞（例如，棒状感光体前体细胞），以及识别，表征，分离和利用该感光体前体细胞的方法。 本发明的组合物和方法尤其可用于研究，临床，诊断，药物发现和治疗应用。
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