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    NEURAL INTERFACE SYSTEM WITH AN EDGE ARRAY
    1.
    发明申请
    NEURAL INTERFACE SYSTEM WITH AN EDGE ARRAY 审中-公开
    具有边缘阵列的神经接口系统

    公开(公告)号：WO2012122502A1

    公开(公告)日：2012-09-13

    申请号：PCT/US2012/028552

    申请日：2012-03-09

    Applicant: NEURONEXUS TECHNOLOGIES ,  SEYMOUR, John ,  HETKE, Jamille ,  VETTER, Rio ,  KIPKE, Daryl ,  PELLINEN, David ,  KONG, K.C.

    Inventor： SEYMOUR, John ,  HETKE, Jamille ,  VETTER, Rio ,  KIPKE, Daryl ,  PELLINEN, David ,  KONG, K.C.

    IPC: A61N1/00

    CPC classification number: A61N1/0534 ,  A61B1/07 ,  A61M25/0009 ,  A61M25/0023 ,  A61N1/0553 ,  A61N5/0601 ,  A61N2005/0632 ,  H05K1/028 ,  H05K1/118 ,  H05K3/10 ,  H05K2201/051 ,  Y10T29/4913 ,  Y10T29/49147 ,  Y10T29/49155

    Abstract: The neural interface system of one embodiment includes a cylindrical shaft, a lateral extension longitudinally coupled to at least a portion of the shaft and having a thickness less than a diameter of the shaft, and an electrode array arranged on the lateral extension and radially offset from the shaft, including electrode sites that electrically interface with their surroundings. The method of one embodiment for making the neural interface system includes forming a planar polymer substrate with at least one metallization layer, patterning on at least one metallization layer an electrode array on a first end of the substrate, patterning conductive traces on at least one metallization layer, rolling a portion of the substrate toward the first end of the substrate, and securing the rolled substrate into a shaft having the first end of the substrate laterally extending from the shaft and the electrode array radially offset from the shaft.

    Abstract translation: 一个实施例的神经接口系统包括圆柱形轴，纵向耦合到轴的至少一部分并且具有小于轴的直径的厚度的横向延伸部和布置在横向延伸部上的径向偏移的电极阵列 轴，包括与其周围环境电接触的电极位置。 用于制造神经接口系统的一个实施例的方法包括：形成具有至少一个金属化层的平面聚合物衬底，在至少一个金属化层上图案化在衬底的第一端上的电极阵列，在至少一个金属化层 将基板的一部分朝向基板的第一端滚动，并且将轧制的基板固定到轴中，该轴具有从轴横向延伸的基板的第一端并且电极阵列从轴径向偏移。

    MEDICAL DEVICE FOR ELECTRICAL STIMULATION
    2.
    发明申请
    MEDICAL DEVICE FOR ELECTRICAL STIMULATION 审中-公开
    用于电刺激的医疗装置

    公开(公告)号：WO2011010257A1

    公开(公告)日：2011-01-27

    申请号：PCT/IB2010/053250

    申请日：2010-07-16

    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  NEURONEXUS TECHNOLOGIES, INC. ,  HARBERTS, Dirk Willem ,  VETTER, Rio

    Inventor： HARBERTS, Dirk Willem ,  VETTER, Rio

    IPC: A61N1/05 ,  A61N1/37 ,  A61N1/08

    CPC classification number: A61N1/0534 ,  A61N1/00 ,  A61N1/086 ,  A61N1/36082

    Abstract: The present invention relates to a medical device (2) for electrical stimulation. The device comprising an implantable elongated lead system (20) having a distal end (21) and a proximal end (22), the lead system comprises one or more electrical conductors (23) for connection to one or more electrodes (24). The one or more electrical conductors are wound along a length axis (25) of the lead system with a plurality of windings, and wherein the density of windings is non-uniformly distributed along the length axis. In an embodiment, the medical device is in the form of a deep brain stimulation (DBS) device.

    Abstract translation: 本发明涉及一种用于电刺激的医疗装置（2）。 所述装置包括具有远端（21）和近端（22）的可植入的细长引线系统（20），所述引线系统包括用于连接到一个或多个电极（24）的一个或多个电导体（23）。 一个或多个电导体沿引线系统的长度轴线（25）以多个绕组缠绕，并且其中绕组的密度沿着长度轴不均匀地分布。 在一个实施例中，医疗装置是深脑刺激（DBS）装置的形式。

    NEURAL INTERFACE SYSTEM
    4.
    发明申请
    NEURAL INTERFACE SYSTEM 审中-公开
    神经接口系统

    公开(公告)号：WO2008109298A3

    公开(公告)日：2008-12-24

    申请号：PCT/US2008055025

    申请日：2008-02-26

    Applicant: NEURONEXUS TECHNOLOGIES INC ,  VETTER RIO ,  KIPKE DARYL ,  PELLINEN DAVID ,  ANDERSON DAVID ,  HETKE JAMILLE FARRAYE

    Inventor： VETTER RIO ,  KIPKE DARYL ,  PELLINEN DAVID ,  ANDERSON DAVID ,  HETKE JAMILLE FARRAYE

    IPC: A61N1/00

    CPC classification number: A61N1/0534 ,  A61B5/04001 ,  A61N1/0539 ,  A61N1/36082

    Abstract: The neural interface system of the preferred embodiments includes an electrode array having a plurality of electrode sites and a carrier that supports the electrode array. The electrode array is coupled to the carrier such that the electrode sites are arranged both circumferentially around the carrier and axially along the carrier. A group of the electrode sites may be simultaneously activated to create an activation pattern. The system of the preferred embodiment is preferably designed for deep brain stimulation, and, more specifically, for deep brain stimulation with fine electrode site positioning, selectivity, tunability, and precise activation patterning. The system of the preferred embodiments, however, may be alternatively used in any suitable environment (such as the spinal cord, peripheral nerve, muscle, or any other suitable anatomical location) and for any suitable reason.

    Abstract translation: 优选实施例的神经接口系统包括具有多个电极位置的电极阵列和支撑电极阵列的载体。 电极阵列耦合到载体，使得电极位置沿着载体周向布置并且沿着载体轴向布置。 可以同时激活一组电极部位以产生激活模式。 优选实施例的系统优选地设计用于深部脑刺激，更具体地，针对具有精细电极位置定位，选择性，可调性和精确激活图案化的深部脑刺激。 然而，优选实施例的系统可以替代地在任何合适的环境（例如脊髓，周围神经，肌肉或任何其他合适的解剖学位置）中使用，并且由于任何合适的原因。

    NEURAL INTERFACE SYSTEM
    6.
    发明申请
    NEURAL INTERFACE SYSTEM 审中-公开
    神经接口系统

    公开(公告)号：WO2008109298A2

    公开(公告)日：2008-09-12

    申请号：PCT/US2008/055025

    申请日：2008-02-26

    Applicant: NEURONEXUS TECHNOLOGIES, INC. ,  VETTER, Rio ,  KIPKE, Daryl ,  PELLINEN, David ,  ANDERSON, David ,  HETKE, Jamille, Farraye

    Inventor： VETTER, Rio ,  KIPKE, Daryl ,  PELLINEN, David ,  ANDERSON, David ,  HETKE, Jamille, Farraye

    IPC: A61N1/05

    CPC classification number: A61N1/0534 ,  A61B5/04001 ,  A61N1/0539 ,  A61N1/36082

    Abstract: The neural interface system of the preferred embodiments includes an electrode array having a plurality of electrode sites and a carrier that supports the electrode array. The electrode array is coupled to the carrier such that the electrode sites are arranged both circumferentially around the carrier and axially along the carrier. A group of the electrode sites may be simultaneously activated to create an activation pattern. The system of the preferred embodiment is preferably designed for deep brain stimulation, and, more specifically, for deep brain stimulation with fine electrode site positioning, selectivity, tunability, and precise activation patterning. The system of the preferred embodiments, however, may be alternatively used in any suitable environment (such as the spinal cord, peripheral nerve, muscle, or any other suitable anatomical location) and for any suitable reason.

    Abstract translation: 本优选实施例的神经界面系统包括具有多个电极部位的电极阵列和支撑电极阵列的载体。 电极阵列耦合到载体，使得电极位置围绕载体周向布置并且沿着载体轴向布置。 一组电极位点可以被同时激活以创建激活模式。 优选实施例的系统优选设计用于深度脑刺激，并且更具体地用于具有精细电极位置定位，选择性，可调谐性和精确激活图案化的深度脑刺激。 然而，优选实施例的系统可以可选地用于任何合适的环境（诸如脊髓，周围神经，肌肉或任何其它合适的解剖位置）并且用于任何合适的原因。

    IMPLANTABLE DEVICE INCLUDING A RESORBABLE CARRIER
    10.
    发明申请
    IMPLANTABLE DEVICE INCLUDING A RESORBABLE CARRIER 审中-公开
    可移植的设备，包括一个可移动的载体

    公开(公告)号：WO2009052425A1

    公开(公告)日：2009-04-23

    申请号：PCT/US2008/080366

    申请日：2008-10-17

    Applicant: NEURONEXUS TECHNOLOGIES ,  HETKE, Jamille, F. ,  KIPKE, Daryl, R. ,  VETTER, Rio, J.

    Inventor： HETKE, Jamille, F. ,  KIPKE, Daryl, R. ,  VETTER, Rio, J.

    IPC: A61N1/00

    CPC classification number: A61B5/04001 ,  A61B5/4041 ,  A61B2562/0209 ,  A61B2562/028 ,  A61B2562/046 ,  A61N1/05 ,  A61N1/0551

    Abstract: An implantable device for body tissue, including an electrical subsystem that flexes within and interfaces with body tissue and a carrier that operates in the following two modes: provides structural support for the electrical subsystem during implantation of the device in body tissue and allows flexing of the electrical subsystem after implantation of the device in body tissue. The implantable device is preferably designed to be implanted into the brain, spinal cord, peripheral nerve, muscle, or any other suitable anatomical location. The implantable device, however, may be alternatively used in any suitable environment and for any suitable reason.

    Abstract translation: 一种用于身体组织的可植入装置，包括在身体组织内部弯曲并与身体组织接触的电子系统，以及以下述两种模式操作的载体：在将装置植入身体组织期间为电子系统提供结构支撑，并允许 电子子系统在植入人体组织后的装置。 可植入装置优选被设计成植入脑，脊髓，周围神经，肌肉或任何其它合适的解剖学位置。 然而，可植入装置可以替代地在任何合适的环境中使用，并且出于任何合适的原因。

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