-
1.发明申请7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS 审中-公开7-（3-羟基）-CHROM-3-EN-6-YL！ - 庚酸和7-（3-羟基）-5,6-二氢萘-2-炔-1-羧酸衍生物调节剂
公开(公告)号：WO2005042509A8
公开(公告)日：2005-11-10
申请号：PCT/US2004035965
申请日：2004-10-29
申请人： ALLERGAN INC , BEARD RICHARD L , DUONG TIEN T , TAKEUCHI JANET A , LI LING , TSANG KWOK YIN , LIU XIAOXIA , VASUDEVAN JAYASREE , WANG LIMING , SINHA SANTOSH C , YUAN HAIQING , CHANDRARATNA ROSHANTHA A
发明人： BEARD RICHARD L , DUONG TIEN T , TAKEUCHI JANET A , LI LING , TSANG KWOK YIN , LIU XIAOXIA , VASUDEVAN JAYASREE , WANG LIMING , SINHA SANTOSH C , YUAN HAIQING , CHANDRARATNA ROSHANTHA A
IPC分类号： A61K31/21 , A61K31/335 , C07C59/72 , C07C69/587 , C07C69/734 , C07D311/58 , A61P3/00
CPC分类号： C07C69/734 , C07C59/72 , C07C2601/02 , C07C2602/28 , C07D311/58
摘要： Compounds for the formula (I) where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects on transiently increasing triglyceride levels and reducing serum thyroxine levels.
摘要翻译： 式（I）化合物，其中变量具有本说明书中定义的含义，能够降低糖尿病哺乳动物血清葡萄糖水平，而不会对短暂增加甘油三酯水平和降低血清甲状腺素水平产生不良副作用。
-
2.发明申请7-(3,5-DIISOPROPYLPHENYL) HEPTATRIENOIC ACID DERIVATIVES HAVING SERUM GLUCOSE REDUCING ACTIVITY 审中-公开7-（3,5-二硝基苯基）具有血清葡萄糖减少活性的高效酸性衍生物
公开(公告)号：WO2004069781A3
公开(公告)日：2004-09-30
申请号：PCT/US2004003160
申请日：2004-02-03
IPC分类号： A61P3/10 , C07C59/68 , C07C69/734 , C07C59/64 , A61K31/202 , A61K31/216
CPC分类号： C07C59/68 , C07C69/734
摘要： Compounds of formula (i) where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effect of reducing serum thyroxine levels.
摘要翻译： 其中变量具有本说明书中定义的含义的式（ⅰ）化合物能够降低糖尿病哺乳动物血清中的葡萄糖水平，而无需降低血清甲状腺素水平的不良副作用。
-
3.发明申请Compounds having selective cyrochrome P450RA-1 or selective cytochrome P450RA-2 inhibitory activity and methods of obtaining the same 审中-公开具有选择性细胞色素P450RA-1或选择性细胞色素P450RA-2抑制活性的化合物及其获得方法
公开(公告)号：WO2005058798A3
公开(公告)日：2006-02-16
申请号：PCT/US2004042897
申请日：2004-12-17
申请人： ALLERGAN INC , VASUDEVAN JAYASREE , WANG LIMING , LIU XIAOXIA , TSANG KOWK YIN , LI LING , TAKEUCHI JANET A , VU THONG , BEARD RICHARD L , BHAT SMITA , VULIGONDA VIDYASAGAR , CHADRARATNA ROSHANTA A
发明人： VASUDEVAN JAYASREE , WANG LIMING , LIU XIAOXIA , TSANG KOWK YIN , LI LING , TAKEUCHI JANET A , VU THONG , BEARD RICHARD L , BHAT SIMITA , VULIGONDA VIDYASAGAR , CHADRARATNA ROSHANTA A
IPC分类号： C07C57/42 , C07C59/64 , C07C59/86 , C07C69/18 , C07C69/73 , C07C69/753 , C07C69/76 , C07C229/34 , C07C229/38 , C07C229/46 , C07C229/50 , C07C275/42 , C07D311/58 , C07D311/64 , C07D311/96 , C07C299/46
CPC分类号： C07C69/73 , C07C57/42 , C07C59/64 , C07C59/86 , C07C69/753 , C07C69/76 , C07C229/34 , C07C229/38 , C07C229/46 , C07C229/50 , C07C275/42 , C07C2601/02 , C07C2602/10 , C07D311/58 , C07D311/64 , C07D311/96
摘要： Compounds of formulas 1 through 17 provided in the specification specifically or selectively inhibit either the cytochrome P450RAI-1 enzyme or the cytochrome P450RAI-2 enzyme.
-
4.发明申请COMPOUNDS HAVING SELECTIVE CYTOCHROME P450RAI-1 OR SELECTIVE CYTOCHROME P450RAI-2 INHIBITORY ACTIVITY AND METHODS OF OBTAINING THE SAME 审中-公开具有选择性细胞色素P450RAI-1或选择性细胞色素P450RAI-2抑制活性的化合物及获得相同物质的方法
公开(公告)号：WO2005058798A8
公开(公告)日：2005-10-13
申请号：PCT/US2004042897
申请日：2004-12-17
申请人： ALLERGAN INC , VASUDEVAN JAYASREE , WANG LIMING , LIU XIAOXIA , TSANG KWOK YIN , LI LING , TAKEUCHI JANET A , VU THONG , BEARD RICHARD L , BHAT SMITA , VULIGONDA VIDYASAGAR , CHANDRARATNA ROSHANTHA A
发明人： VASUDEVAN JAYASREE , WANG LIMING , LIU XIAOXIA , TSANG KWOK YIN , LI LING , TAKEUCHI JANET A , VU THONG , BEARD RICHARD L , BHAT SMITA , VULIGONDA VIDYASAGAR , CHANDRARATNA ROSHANTHA A
IPC分类号： C07C57/42 , C07C59/64 , C07C59/86 , C07C69/18 , C07C69/73 , C07C69/753 , C07C69/76 , C07C229/34 , C07C229/38 , C07C229/46 , C07C229/50 , C07C275/42 , C07D311/58 , C07D311/64 , C07D311/96
CPC分类号： C07C69/73 , C07C57/42 , C07C59/64 , C07C59/86 , C07C69/753 , C07C69/76 , C07C229/34 , C07C229/38 , C07C229/46 , C07C229/50 , C07C275/42 , C07C2601/02 , C07C2602/10 , C07D311/58 , C07D311/64 , C07D311/96
摘要： Compounds of formulas 1 through 17 provided in the specification specifically or selectively inhibit either the cytochrome P450RAI-1 enzyme or the cytochrome P450RAI-2 enzyme.
摘要翻译： 说明书中提供的式1至17的化合物特异性地或选择性地抑制细胞色素P450RAI-1酶或细胞色素P450RAI-2酶。
-
5.发明申请
公开(公告)号：WO0218361A3
公开(公告)日：2003-07-31
申请号：PCT/US0125443
申请日：2001-08-14
申请人： ALLERGAN INC
IPC分类号： C07D233/60 , A61K31/192 , A61K31/195 , A61K31/196 , A61K31/216 , A61K31/235 , A61K31/24 , A61K31/352 , A61K31/353 , A61K31/4164 , A61K31/4174 , A61K31/47 , A61K31/472 , A61K31/4747 , A61K31/55 , A61P3/00 , A61P9/00 , A61P17/00 , A61P27/02 , A61P29/00 , A61P31/12 , A61P35/00 , A61P37/00 , A61P43/00 , C07C59/64 , C07C59/66 , C07C59/72 , C07C59/86 , C07C59/88 , C07C65/21 , C07C65/28 , C07C65/38 , C07C69/773 , C07C229/48 , C07D215/14 , C07D217/04 , C07D221/20 , C07D311/70 , C07D311/96 , C07D311/74 , C07C57/38 , C07C59/82 , C07C65/19 , C07C229/46 , C07D215/06 , C07D335/06 , C07D521/00
摘要： Compounds having the Formulas 1 through 8, wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids.
摘要翻译： 具有式1至8的化合物，其中符号具有本说明书中定义的含义是细胞色素P450RAI（视黄酸诱导型）酶的抑制剂，并用于治疗对类维生素A的治疗有反应的疾病。
-
-
-
-
搜索结果
5 条记录 (耗时 0.011 秒)
