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    METHOD OF TREATMENT OF COMPLEMENT MEDIATED NEURODEVELOPMENTAL DISORDER SECONDARY TO ZIKA VIRUS INFECTION
    2.
    发明申请
    METHOD OF TREATMENT OF COMPLEMENT MEDIATED NEURODEVELOPMENTAL DISORDER SECONDARY TO ZIKA VIRUS INFECTION 审中-公开
    治疗ZIKA病毒感染次级补充介导的神经发育障碍的方法

    公开(公告)号：WO2017140903A1

    公开(公告)日：2017-08-24

    申请号：PCT/EP2017/053714

    申请日：2017-02-17

    申请人： VOLUTION IMMUNO PHARMACEUTICALS SA

    发明人： WESTON-DAVIES, Wynne H

    IPC分类号： A61K38/17 ,  A61P31/12

    CPC分类号： A61K38/1767 ,  Y02A50/391

    摘要： The present invention relates to methods of treating or preventing complement mediated neurodevelopmental disorders secondary to maternal infection with Zika virus, comprising administering to a pregnant female or to a foetus or embryo, a therapeutically or prophylactically effective amount of an agent which is a protein comprising amino acids 19 to 168 of the amino acid sequence in Figure 2 (SEQ ID NO: 2) or a functional equivalent of this protein.

    摘要翻译： 本发明涉及治疗或预防继发于母体寨卡病毒感染的补体介导的神经发育病症的方法，其包括向怀孕女性或胎儿或胚胎施用治疗或预防有效量的 包含图2（SEQ ID NO：2）中的氨基酸序列的氨基酸19至168或该蛋白质的功能等同物的蛋白质的试剂。

    PROMOTING MUSCLE BUILDING AND REPAIR AND TREATING DISORDERS RELATED TO COLLAGEN AND PERTINENT PROTEINS BY USING SHILAJIT
    3.
    发明申请
    PROMOTING MUSCLE BUILDING AND REPAIR AND TREATING DISORDERS RELATED TO COLLAGEN AND PERTINENT PROTEINS BY USING SHILAJIT 审中-公开
    通过使用SHILAJIT促进与胶原蛋白和蛋白质相关的肌肉建筑和修复和治疗疾病

    公开(公告)号：WO2016054433A1

    公开(公告)日：2016-04-07

    申请号：PCT/US2015/053587

    申请日：2015-10-01

    申请人： NATREON, INC.

    发明人： SEN, Chandan, K.

    IPC分类号： A61K8/97 ,  A61K8/98 ,  A61K35/10

    CPC分类号： A61K35/02 ,  A61K8/965 ,  A61K8/97 ,  A61K8/98 ,  A61K8/99 ,  A61K31/352 ,  A61K31/366 ,  A61K31/538 ,  A61K35/10 ,  A61K38/1767 ,  A61Q19/08 ,  A61K2300/00

    摘要： A method of using Shilajit or its individual components, or a combination of two or more of these components, to induce the body of a mammal, including that of a human, to synthesize new collagen and the related extracellular matrix proteins, thus promoting the health of all of the tissues and organs containing collagen and the related extracellular matrix proteins, including skin, connective tissue, muscle, cartilage, bone, and teeth and improve muscle building and regeneration, and/or treat collagen-related disorders is presented.

    摘要翻译： 使用Shilajit或其单独组分或这些组分中的两种或更多种的组合来诱导哺乳动物（包括人类）的身体合成新的胶原蛋白和相关的细胞外基质蛋白的方法，从而促进健康 包括皮肤，结缔组织，肌肉，软骨，骨骼和牙齿的所有组织和器官以及相关的细胞外基质蛋白，并改善肌肉的建立和再生，和/或治疗胶原蛋白相关疾病。

    ANTI-VIRAL CNIDARINS
    8.
    发明申请
    ANTI-VIRAL CNIDARINS 审中-公开
    反传染媒介

    公开(公告)号：WO2015106086A1

    公开(公告)日：2015-07-16

    申请号：PCT/US2015/010797

    申请日：2015-01-09

    申请人： THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

    发明人： O'KEEFE, Barry R. ,  MCMAHON, James B. ,  RAMESSAR, Koreen ,  XIONG, Chang-yun

    IPC分类号： A61K38/00 ,  C07K14/435

    CPC分类号： C07K14/43595 ,  A61K38/00 ,  A61K38/1767 ,  A61K48/00 ,  C07K14/435 ,  C07K16/18

    摘要： An isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 1, 2, or 3, wherein the at least eight contiguous amino acids have anti-viral activity, as well as an isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 1, 2, or 3, wherein the at least eight contiguous amino acids have anti-viral activity, a vector comprising such an isolated and purified nucleic acid molecule, a host cell comprising the nucleic acid molecule, optionally in the form of a vector, a method of producing an anti-viral polypeptide or conjugate thereof, the anti-viral polypeptide itself, a conjugate or fusion protein comprising the anti-viral polypeptide, and compositions comprising an effective amount of the anti-viral polypeptide or conjugate or fusion protein thereof. Further provided are methods of inhibiting prophylactically or therapeutically a viral infection of a host.

    摘要翻译： 分离和纯化的核酸分子，其编码包含SEQ ID NO：1,2或3的至少8个连续氨基酸的多肽，其中所述至少8个连续氨基酸具有抗病毒活性，以及​​分离和 纯化的核酸分子，其编码包含SEQ ID NO：1,2或3的至少8个连续氨基酸的多肽，其中所述至少8个连续氨基酸具有抗病毒活性，包含这种分离和纯化的核酸的载体 酸分子，包含核酸分子的宿主细胞，任选以载体的形式，产生抗病毒多肽或其缀合物的方法，抗病毒多肽本身，包含抗病毒的缀合物或融合蛋白 多肽和包含有效量的抗病毒多肽或其结合物或其融合蛋白的组合物。 还提供了预防性或治疗性地抑制宿主的病毒感染的方法。