利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

161 条记录 (耗时 0.025 秒)

    SYSTEM FOR CREATING A GRAFT DEVICE
    1.
    发明申请
    SYSTEM FOR CREATING A GRAFT DEVICE 审中-公开
    用于创建移植设备的系统

    公开(公告)号：WO2017112710A1

    公开(公告)日：2017-06-29

    申请号：PCT/US2016/067879

    申请日：2016-12-20

    申请人： NEOGRAFT TECHNOLOGIES, INC.

    发明人： LEESON, Cory ,  MANNARINO, Matthew ,  EL-KURDI, Mohammed ,  MCGRATH, Jon

    IPC分类号： A61L27/36 ,  D01D5/084 ,  D01D13/02

    CPC分类号： A61L27/507 ,  A61L27/16 ,  A61L27/3625 ,  A61L27/3629 ,  D01D5/0038 ,  D01D5/0076 ,  D01D13/02 ,  C08L23/12

    摘要： Provided are systems for applying a polymer fiber matrix to a tubular conduit to create a graft device. The system comprises a polymer solution comprising at least one polymer and at least one solvent; a polymer delivery assembly constructed and arranged to receive the polymer solution and to deliver the polymer fiber matrix to the tubular conduit; a rotating assembly constructed and arranged to rotate at least one of the tubular conduit or the polymer delivery assembly; and a controller constructed and arranged to control the polymer delivery assembly and the rotating assembly. The system is constructed and arranged to reduce the amount of the solvent in the graft device. Methods of applying a polymer fiber matrix with reduced solvent are also provided.

    摘要翻译： 提供了用于将聚合物纤维基质施加到管状导管以形成移植物装置的系统。 该系统包含含有至少一种聚合物和至少一种溶剂的聚合物溶液; 聚合物输送组件，其被构造和布置成接收聚合物溶液并将聚合物纤维基质输送到管状导管; 旋转组件，其被构造和布置成旋转管状导管或聚合物输送组件中的至少一个; 以及构造和布置成控制聚合物输送组件和旋转组件的控制器。 该系统被构造并布置成减少移植装置中的溶剂的量。 还提供了使用减少溶剂的聚合物纤维基质的方法。

    VASCULAR CASTED PROSTHESES AND METHODS OF FORMING SAME FOR TREATING BIOLOGICAL TISSUE
    2.
    发明申请
    VASCULAR CASTED PROSTHESES AND METHODS OF FORMING SAME FOR TREATING BIOLOGICAL TISSUE 审中-公开
    血管生成组织的形成及其形成方法

    公开(公告)号：WO2016153534A1

    公开(公告)日：2016-09-29

    申请号：PCT/US2015/026676

    申请日：2015-04-20

    申请人： CORMATRIX CARDIOVASCULAR, INC.

    发明人： MATHENY, Robert, G. ,  FERRANTA, Craig, N.

    IPC分类号： A61L27/36

    CPC分类号： A61L27/3633 ,  A61L27/3625 ,  A61L27/48 ,  A61L27/52 ,  A61L27/54 ,  A61L2300/41 ,  A61L2300/414 ,  A61L2300/422 ,  A61L2300/45 ,  A61L2300/64 ,  C08L5/08 ,  C08L67/04

    摘要： Bioremodelable tissue prostheses having a vasculature that is infused with a biomaterial composition. The present invention is directed to casted constructs for treating, reconstructing or replacing damaged or diseased biological tissue. In a preferred embodiment, the casted constructs comprise an ECM member having a biomaterial composition disposed within the vasculature of the ECM member. In some embodiments of the invention, the casted constructs comprise a seamless ECM material derived from a mammalian tissue source. According to the invention, the seamless ECM material can be derived from various mammalian tissue sources, including, without limitation, small intestine, large intestine and umbilical cord.

    摘要翻译： 具有注入生物材料组合物的脉管系统的生物可重组组织假体。 本发明涉及用于治疗，重建或替代损伤的或患病的生物组织的铸造构造物。 在优选的实施方案中，铸塑构件包含具有设置在ECM构件的脉管系统内的生物材料组合物的ECM构件。 在本发明的一些实施方案中，铸造的构建体包含衍生自哺乳动物组织来源的无缝ECM材料。 根据本发明，无缝ECM材料可以衍生自各种哺乳动物组织来源，包括但不限于小肠，大肠和脐带。

    PRE-ASSEMBLED BIOPROSTHETIC VALVE AND SEALED CONDUIT
    4.
    发明申请
    PRE-ASSEMBLED BIOPROSTHETIC VALVE AND SEALED CONDUIT 审中-公开
    预组装的生物阀和密封管

    公开(公告)号：WO2013184552A8

    公开(公告)日：2014-12-04

    申请号：PCT/US2013043838

    申请日：2013-06-03

    申请人： EDWARDS LIFESCIENCES CORP

    发明人： CAMPBELL LOUIS A ,  BOBO DONALD E JR ,  WRIGHT GREGORY A ,  CHEUNG TAK G

    IPC分类号： A61F2/24 ,  A61F2/02 ,  A61M39/22

    CPC分类号： A61F2/2418 ,  A61F2/0095 ,  A61F2/06 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2427 ,  A61F2210/0004 ,  A61F2220/0075 ,  A61F2310/00371 ,  A61F2310/00383 ,  A61L27/222 ,  A61L27/24 ,  A61L27/3625 ,  A61L27/3687 ,  A61L27/507 ,  A61L2430/20 ,  A61L2430/40

    摘要： A valved conduit including a bioprosthetic valve, such as a heart valve, and a tubular conduit sealed with a bioresorbable material. The bioprosthetic heart valve includes prosthetic tissue that has been treated such that the tissue may be stored dry for extended periods without degradation of functionality of the valve. The bioprosthetic heart valve may have separate bovine pericardial leaflets or a whole porcine valve. The sealed conduit includes a tubular matrix impregnated with a bioresorbable medium such as gelatin or collagen. The valved conduit is stored dry in packaging in which a desiccant pouch is supplied having a capacity for absorbing moisture within the packaging limited to avoid drying the bioprosthetic tissue out beyond a point where its ability to function in the bioprosthetic heart valve is compromised. The heart valve may be sewn within the sealed conduit or coupled thereto with a snap-fit connection.

    摘要翻译： 包括生物假体瓣膜（例如心脏瓣膜）和用生物可再吸收材料密封的管状导管的阀门导管。 生物假体心脏瓣膜包括经过处理的假体组织，使得组织可以长时间保存干燥，而不会降低瓣膜的功能。 生物假体心脏瓣膜可以具有单独的牛心包瓣或整个猪瓣。 密封导管包括浸渍有生物可吸收介质如明胶或胶原的管状基质。 带阀的导管在包装中储存，其中提供干燥剂袋，其具有吸收包装内的水分的能力，以避免将生物假体组织干燥超过其在生物假体心脏瓣膜中起作用的能力受损的程度。 心脏瓣膜可以缝合在密封导管内或用卡扣配合连接在其上。

    BIOCOMPATIBLE CONTAINMENT MEMBER FOR BONE AUGMENTATION SURGERY MADE OF PROCESSED NATURAL MEMBRANE FROM AN ANIMAL DONOR
    7.
    发明申请
    BIOCOMPATIBLE CONTAINMENT MEMBER FOR BONE AUGMENTATION SURGERY MADE OF PROCESSED NATURAL MEMBRANE FROM AN ANIMAL DONOR 审中-公开
    生物化学成分由动物捐赠者处理的自然膜的骨骼愈合手术

    公开(公告)号：WO2013120067A1

    公开(公告)日：2013-08-15

    申请号：PCT/US2013/025557

    申请日：2013-02-11

    申请人： OSSEOUS TECHNOLOGIES OF AMERICA

    发明人： CHEUNG, David

    IPC分类号： A61F2/28

    CPC分类号： A61L27/3604 ,  A61F2/2803 ,  A61F2/2846 ,  A61F2002/2835 ,  A61F2002/30581 ,  A61F2310/00371 ,  A61L27/12 ,  A61L27/3625 ,  A61L27/365 ,  A61L27/3687 ,  A61L27/58 ,  A61L2430/02 ,  A61L2430/38 ,  A61L2430/40

    摘要： A surgically implantable containment member for maintaining a bone augmentation material in a desired location and/or configuration following implantation in a human or other mammalian patient, in which the containment member is made of a natural membrane, such as pericardium, isolated from an animal donor and processed to avoid inflammation or tissue rejection, and a method of bone augmentation using such a containment member. In a particularly preferred embodiment, the containment member has a window which rapidly dissipates upon exposure to bodily fluids after implantation to expose bone augmentation material contained within the containment member to an adjacent bone to be augmented.

    摘要翻译： 一种用于在人或其它哺乳动物患者植入之后将骨增强材料保持在所需位置和/或构型中的手术可植入的容纳构件，其中所述容纳构件由从动物供体分离的天然膜例如心包膜制成 并且被加工以避免炎症或组织排斥，以及使用这种容纳构件的骨增大的方法。 在特别优选的实施例中，容纳构件具有窗口，其在植入之后暴露于体液时迅速消散，以将包含在容纳构件内的骨增强材料暴露于要增强的相邻骨骼。