SYSTEMS FOR AND METHOD OF QUANTITATIVE MEASURE OF COMPONENTS OF A LIQUID
    2.
    发明申请
    SYSTEMS FOR AND METHOD OF QUANTITATIVE MEASURE OF COMPONENTS OF A LIQUID 审中-公开
    液体组分定量测量系统和方法

    公开(公告)号:WO2017137805A1

    公开(公告)日:2017-08-17

    申请号:PCT/IB2016/050723

    申请日:2016-02-11

    摘要: A system (2) for the optical spectrophotometric assay of components in of a liquid sample (40) comprises an optical spectrophotometer (4) having an inspection zone (18) for receiving a sample for assay (40a); a radiation source (10) configured to generate optical radiation for supply into the inspection zone (18) to impinge on and thereby interact with a received sample for assay (40a); and a nebulizer (24) configured to discharge an aerosol (44) of the liquid sample (40) towards a one of one or more collection surfaces (32) located spaced apart from the nebulizer (24) and disposed to receive discharged aerosol (44) to form the sample for assay (40a).

    摘要翻译: 用于光学分光光度测定液体样品(40)中组分的系统(2)包括光学分光光度计(4),该光学分光光度计具有用于接收用于测定的样品(40a)的检测区域(18) ); 辐射源(10),其被配置为产生光辐射以供应到所述检查区域(18)中以撞击并因此与用于分析的接收样本(40a)相互作用; 和喷雾器(24),所述喷雾器构造成将液体样品(40)的气雾剂(44)朝向与所述喷雾器(24)间隔开设置的一个或多个收集表面(32)中的一个排出,并且设置成接收排出的气雾剂 )以形成用于测定的样品(40a)。

    DETERMINING THE QUANTITY OF A TAGGANT IN A LIQUID SAMPLE
    3.
    发明申请
    DETERMINING THE QUANTITY OF A TAGGANT IN A LIQUID SAMPLE 审中-公开
    确定液体样品中标签的数量

    公开(公告)号:WO2017019337A1

    公开(公告)日:2017-02-02

    申请号:PCT/US2016/042560

    申请日:2016-07-15

    申请人: AUTHENTIX, INC.

    IPC分类号: G01N21/64 G01N33/28

    摘要: Device and methods for detecting/quantifying a fluorescent taggant in a liquid sample. Generally, the liquid samples are fuels having low concentrations (measured in ppb) of a fluorescent taggant. The detection/quantification generates a predicted concentration of the fluorescent tagging compound using a process selected from the group of a multivariate process, a background subtraction process, or a combination of both. The invention addresses the detection of an adulteration of gasoline and diesel fuels.

    摘要翻译: 用于检测/定量液体样品中的荧光标记物的装置和方法。 通常,液体样品是荧光标记物浓度低(以ppb计)的燃料。 检测/定量使用选自多变量过程,背景减除过程或两者的组合的过程产生荧光标记化合物的预测浓度。 本发明涉及汽油和柴油燃料掺假的检测。

    REAGENT-FREE IDENTIFICATION OF BACTERIA CONTAINING RESISTANCE GENES USING A RAPID INTRINSIC FLUORESCENCE METHOD
    4.
    发明申请
    REAGENT-FREE IDENTIFICATION OF BACTERIA CONTAINING RESISTANCE GENES USING A RAPID INTRINSIC FLUORESCENCE METHOD 审中-公开
    使用快速内在荧光法测定含有耐药基因的细菌

    公开(公告)号:WO2016142825A1

    公开(公告)日:2016-09-15

    申请号:PCT/IB2016/051247

    申请日:2016-03-04

    IPC分类号: G06F19/00

    摘要: This invention relates to a method that allows for the differentiation of isolates of commonly encountered bacteria that contain specific antibiotic-resistance genes from similar isolates that do not harbor the gene. More particularly, the invention relates to a method that utilizes an automated rapid platform system that employs intrinsic fluorescence, optical data analysis, and artificial intelligence methods to analyze multi-dimensional optical characteristics of bacterial strains.

    摘要翻译: 本发明涉及允许从不含基因的相似分离物中分离含有特异抗生素抗性基因的常见细菌的分离物的方法。 更具体地,本发明涉及利用采用固有荧光,光学数据分析和人工智能方法来分析细菌菌株的多维光学特性的自动化快速平台系统的方法。

    OPTIMIZED SPECTRAL MATCHING AND DISPLAY
    5.
    发明申请
    OPTIMIZED SPECTRAL MATCHING AND DISPLAY 审中-公开
    优化光谱匹配和显示

    公开(公告)号:WO2016141198A1

    公开(公告)日:2016-09-09

    申请号:PCT/US2016/020715

    申请日:2016-03-03

    IPC分类号: G01N21/25 G01N21/31 G01J3/28

    摘要: Systems, methods, and apparatuses are provided for identifying an optimal spectral match and potentially display the compared spectra. A sample spectrum of a sample substance can be compared to reference spectra to identify matches, thereby determining possibilities for what the sample substance is. Correction parameter(s) may be used for the sample spectrum and/or the reference spectrum. Initial value(s) for the correction parameter(s) can be applied to the sample spectrum and/or a reference spectrum, and a similarity score can be determined. Value(s) for the correction parameter(s) can be updated and iteratively improved to provide an optimal similarity score that satisfies a convergence criterion. Data about the reference substances having optimal similarity scores that are above a threshold can be output to a user, e.g., the reference spectra can overlay the sample spectrum. A user can then make a final determination of which reference substance corresponds to the sample substance.

    摘要翻译: 提供系统,方法和装置用于识别最佳光谱匹配并潜在地显示所比较的光谱。 可以将样品物质的样品光谱与参考光谱进行比较以鉴定匹配,从而确定样品物质的可能性。 校正参数可用于样品光谱和/或参考光谱。 校正参数的初始值可以应用于样本频谱和/或参考频谱,并且可以确定相似性分数。 可以更新和迭代地改进校正参数的值,以提供满足收敛准则的最佳相似度分数。 关于具有高于阈值的最佳相似性评分的参考物质的数据可以输出给用户,例如,参考光谱可以覆盖样品光谱。 然后,用户可以最终确定哪个参考物质对应于样品物质。

    SPECTRAL IMAGING SYSTEM FOR REMOTE AND NONINVASIVE DETECTION OF TARGET SUBSTANCES USING SPECTRAL FILTER ARRAYS AND IMAGE CAPTURE ARRAYS
    6.
    发明申请
    SPECTRAL IMAGING SYSTEM FOR REMOTE AND NONINVASIVE DETECTION OF TARGET SUBSTANCES USING SPECTRAL FILTER ARRAYS AND IMAGE CAPTURE ARRAYS 审中-公开
    使用光谱滤波器阵列和图像捕获阵列进行远程和非目标检测目标物质的光谱成像系统

    公开(公告)号:WO2015195746A1

    公开(公告)日:2015-12-23

    申请号:PCT/US2015/036146

    申请日:2015-06-17

    申请人: INNOPIX, INC.

    IPC分类号: G01J3/02

    摘要: An approach to noninvasively and remotely detect the presence, location, and/or quantity of a target substance in a scene via a spectral imaging system comprising a spectral filter array and image capture array. For a chosen target substance, a spectral filter array is provided that is sensitive to selected wavelengths characterizing the electromagnetic spectrum of the target substance. Elements of the image capture array are optically aligned with elements of the spectral filter array to simultaneously capture spectrally filtered images. These filtered images identify the spectrum of the target substance. Program instructions analyze the acquired images to compute information about the target substance throughout the scene. A color-coded output image may be displayed on a smartphone or computing device to indicate spatial and quantitative information about the detected target substance. The system desirably includes a library of interchangeable spectral filter arrays, each sensitive to one or more target substances.

    摘要翻译: 通过包括光谱滤波器阵列和图像捕获阵列的光谱成像系统非侵入性地远程地检测场景中目标物质的存在,位置和/或数量的方法。 对于所选择的目标物质,提供对表征目标物质的电磁光谱的选定波长敏感的光谱滤波器阵列。 图像捕获阵列的元件与光谱滤波器阵列的元件光学对准,以同时捕获经过频谱滤波的图像。 这些过滤图像识别目标物质的光谱。 程序指令分析所获取的图像以在整个场景中计算关于目标物质的信息。 颜色编码的输出图像可以显示在智能电话或计算设备上以指示关于检测到的目标物质的空间和定量信息。 该系统期望地包括可互换光谱滤光器阵列的库,每个对一种或多种目标物质敏感。

    A METHOD OF ANALYSING A SAMPLE INCLUDING A MICROORGANISM OF INTEREST
    7.
    发明申请
    A METHOD OF ANALYSING A SAMPLE INCLUDING A MICROORGANISM OF INTEREST 审中-公开
    分析包括利益相关者样本的样本的方法

    公开(公告)号:WO2015128650A1

    公开(公告)日:2015-09-03

    申请号:PCT/GB2015/050551

    申请日:2015-02-26

    IPC分类号: C12Q1/04 G01N21/33

    摘要: A method of analysing a sample including a microorganism of interest. The method includes exposing the sample to an antimicrobial; after exposing the sample to the antimicrobial, applying an absorption-based and/or scattering-based spectroscopic technique to the sample to obtain spectrum data whose spectral profile has been influenced by exposing the sample to the antimicrobial, wherein applying the absorption-based and/or scattering-based spectroscopic technique to the sample includes irradiating the sample with UV-Vis radiation; obtaining information regarding the susceptibility/resistance of the microorganism of interest to the antimicrobial from the spectrum data. The absorption-based and/or scattering-based spectroscopic technique may be applied to the sample no more than 60 minutes after the initial exposure of the sample to the antimicrobial. The method may be useful to obtain information regarding the susceptibility/resistance of a bacterium, such as a bacterium responsible for causing a UTI, to an antibiotic in a rapid and reliable manner.

    摘要翻译: 一种分析包含感兴趣的微生物的样品的方法。 该方法包括将样品暴露于抗微生物剂; 在将样品暴露于抗微生物剂之后,向样品施加基于吸收的和/或散射的光谱技术以获得其光谱曲线已经通过将样品暴露于抗微生物剂而受到影响的光谱数据,其中应用基于吸收的和/ 或基于散射的光谱技术包括用UV-Vis辐射照射样品; 从光谱数据获得关于感兴趣的微生物对抗微生物的敏感性/抗性的信息。 在将样品初次暴露于抗微生物剂后不超过60分钟,基于吸收和/或散射的光谱技术可以应用于样品。 该方法可以用于以快速且可靠的方式获得关于引起UTI的细菌如抗生素的细菌的敏感性/抗性的信息。

    DETERMINATION DE LA CONCENTRATION D'UN COMPOSANT DANS UN FLUIDE D'UN ANIMAL PAR ANALYSE SPECTROSCOPIQUE D'UN AUTRE FLUIDE
    8.
    发明申请
    DETERMINATION DE LA CONCENTRATION D'UN COMPOSANT DANS UN FLUIDE D'UN ANIMAL PAR ANALYSE SPECTROSCOPIQUE D'UN AUTRE FLUIDE 审中-公开
    通过其他流体的光谱分析确定动物中一种成分的组分浓度

    公开(公告)号:WO2015055966A1

    公开(公告)日:2015-04-23

    申请号:PCT/FR2014/052650

    申请日:2014-10-17

    发明人: BROUTIN, Pierre

    摘要: Procédé de calibration d'un appareil de spectroscopie infrarouge pour réaliser des spectres en vue de déterminer la concentration d'un composant C1 dans un fluide F1 d'un animal, qui comprend les étapes consistant à : a)- se munir d'échantillons dudit fluide F1 et d'un fluide F2 différent du fluide F1, provenant de chaque animal appartenant à un lot d'animaux représentatifs, le fluide F2 contenant des quantités décelables d'au moins un composant C2 qui a une relation directe ou indirecte avec une voie métabolique du composant C1, b)- mesurer la concentration du composant C1 dans les échantillons de fluide F1 à l'aide d'une méthode de référence, c)- réaliser le spectre d'absorption IR complet des échantillons de fluide F2, d)- identifier sur les spectres d'absorption des échantillons de fluide F2, les plages spectrales qui sont corrélées avec la concentration du composant C1 dans les échantillons de fluide F1, et e)- calculer en se fondant sur au moins une desdites plages spectrales corrélées, un modèle mathématique prédictif de la concentration du composant C1 dans le fluide F1. Le procédé s'applique à la prédiction des teneurs de composants d'un premier fluide à partir du dosage de composants dans un autre fluide. Il s'applique aussi à l'identification de composés impliqués dans une voie métabolique.

    摘要翻译: 本发明涉及一种用于校准红外光谱仪的方法,以产生光谱,以便确定动物的一个流体F1中的组分C1的浓度,其包括以下步骤:a)获得所述流体F1的样品 以及来自属于一组代表性动物的每只动物的流体F1以外的流体F2,流体F2含有可检测量的至少一种与组分C1的代谢途径直接或间接相关的组分C2; b)通过参考方法测量流体F1样品中组分C1的浓度; c)产生流体F2样品的完全IR吸收光谱; d)在流体F2的样品的吸收光谱中识别与流体F1的样品中的组分C1的浓度相关的光谱范围; 以及e)基于所述相关光谱范围中的至少一个,计算流体F1中的组分C1的浓度的预测数学模型。 该方法用于从另一流体中的组分的剂量预测第一流体中的组分的水平。 该方法还用于鉴定参与代谢途径的化合物。

    METHOD AND APPARATUS FOR REAL-TIME MEASUREMENT OF FUEL GAS COMPOSITIONS HEATING VALUES
    9.
    发明申请
    METHOD AND APPARATUS FOR REAL-TIME MEASUREMENT OF FUEL GAS COMPOSITIONS HEATING VALUES 审中-公开
    燃料气体组分加热值的实时测量方法和装置

    公开(公告)号:WO2014182386A1

    公开(公告)日:2014-11-13

    申请号:PCT/US2014/032112

    申请日:2014-03-28

    IPC分类号: G01N21/85

    摘要: An exemplary embodiment can be an apparatus for real-time, in situ measurement of gas compositions and heating values. The apparatus includes a near infrared sensor for measuring concentrations of hydrocarbons and carbon dioxide, a mid infrared sensor for measuring concentrations of carbon monoxide and a semiconductor based sensor for measuring concentrations of hydrogen gas. A data processor having a computer program for reducing the effects of cross-sensitivities of the sensors to components other than target components of the sensors is also included. Also provided are corresponding or associated methods for real-time, in situ determination of a composition and heating value of a fuel gas.

    摘要翻译: 示例性实施例可以是用于实时,原位测量气体组成和加热值的装置。 该装置包括用于测量碳氢化合物和二氧化碳浓度的近红外传感器,用于测量一氧化碳浓度的中红外传感器和用于测量氢气浓度的基于半导体的传感器。 还包括具有计算机程序的数据处理器,该计算机程序用于将传感器的交叉敏感度对传感器的目标部件以外的部件的影响降低。 还提供了用于实时,原位测定燃料气体的组成和发热值的相应或相关联的方法。

    SYSTEM FOR AND METHOD OF COMBINED LIBS AND IR ABSORPTION SPECTROSCOPY INVESTIGATIONS
    10.
    发明申请
    SYSTEM FOR AND METHOD OF COMBINED LIBS AND IR ABSORPTION SPECTROSCOPY INVESTIGATIONS 审中-公开
    组合LIBS和红外吸收光谱研究的系统和方法

    公开(公告)号:WO2014146719A1

    公开(公告)日:2014-09-25

    申请号:PCT/EP2013/056091

    申请日:2013-03-22

    摘要: A system (102) for determining properties of a sample (114) comprises a LIBS detector (104,106) and an infra-red absorption detector (108,110) for interrogating a sample (114) to generate LIBS spectral data and infra-red absorption spectral data respectively; and a data processor (112) adapted to apply at least one chemometric prediction model, each constructed to link, preferably quantitatively link, features of both LIBS and absorption spectral data to a different specific property of the sample, to a combined dataset derived from at least portions of both the LIBS and the absorption data to generate therefrom a determination, preferably a quantitative determination, of the specific property linked by that model.

    摘要翻译: 用于确定样品(114)的性质的系统(102)包括用于询问样品(114)以产生LIBS光谱数据和红外吸收光谱数据的LIBS检测器(104,106)和红外吸收检测器(108,110) 分别; 以及适于应用至少一个化学计量预测模型的数据处理器(112),每个化学计量预测模型被构造为将LIBS和吸收光谱数据的特征优选地定量地链接到样本的不同特定属性, LIBS和吸收数据的最少部分由此产生由该模型链接的特定属性的确定,优选地定量确定。