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公开(公告)号:WO2023049873A1
公开(公告)日:2023-03-30
申请号:PCT/US2022/076981
申请日:2022-09-23
申请人: THIRD POLE, INC.
IPC分类号: A61M16/12 , A61K33/00 , A61M16/10 , A61M16/20 , B01J19/08 , C01B21/20 , C01B21/30 , G01D21/02
摘要: A drug delivery system including a housing having a distal end with an inlet through which an inspiratory flow of air passes into the housing, a proximal end having a patient interface attached, the patient interface being configured to interface with a user, and an inspiratory flow pathway extending from the distal end to the proximal end of the housing. A nitric oxide (NO) source is positioned within the housing and is configured to deliver NO-containing gas to the patient interface. A secondary drug source is positioned within the housing and is configured to deliver a secondary drug to the patient interface. A controller is configured to control an amount of NO-containing gas and an amount of the secondary drug delivered using a control scheme.
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公开(公告)号:WO2023018992A1
公开(公告)日:2023-02-16
申请号:PCT/US2022/040260
申请日:2022-08-12
申请人: THIRD POLE, INC.
发明人: MILES, Christopher , SHAJII, Ali , SMITH, Donald K. , APOLLONIO, Benjamin J. , HALL, Gregory W.
摘要: System and methods are provided for generating nitric oxide (NO). In some embodiments, systems comprise a microwave generator configured to produce microwave energy of varying pulse duration, pulse frequency, and power level and a microwave cavity configured to utilize microwave energy to generate a plasma ball within a flow of reactant gas containing nitrogen and oxygen flowing through the microwave cavity to produce a product gas containing NO. At least one stub can be positioned in the microwave cavity and is configured to focus the microwave energy at a location at which the plasma ball is formed. A controller in electrical communication with the microwave generator can be configured to control the microwave generator to initiate and maintain the plasma ball so the plasma ball is suspended in the flow of reactant gas and does not contact a surface of the at least one stub and the microwave cavity.
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公开(公告)号:WO2022205602A1
公开(公告)日:2022-10-06
申请号:PCT/CN2021/096578
申请日:2021-05-28
申请人: 深圳市科曼医疗设备有限公司
摘要: 本申请公开了一种气体混合装置,包括壳体、进气管及出气管,壳体具有用于混合多种目标气体的混合腔;进气管与混合腔连通,进气管至少包括第一进气管和第二进气管,第一进气管与混合腔的周壁相交形成第一相交点,且第一进气管的中心轴线与混合腔的第一相交点所在的径向呈夹角设置;第二进气管与混合腔的周壁相交形成第二相交点,且第二进气管的中心轴线与混合腔的第二相交点所在的径向呈夹角设置;第一进气管的进气方向和第二进气管的进气方向为环绕混合腔的同一时针方向;出气管则与混合腔连通。运用本技术方案解决了因混和气体的混合状态不稳定而影响氧浓度检测、因混合气体杂乱相互碰撞而导致阻力增大,进而影响呼吸机性能的技术问题。
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公开(公告)号:WO2022201370A1
公开(公告)日:2022-09-29
申请号:PCT/JP2021/012307
申请日:2021-03-24
申请人: MiZ株式会社
摘要: 精度の高い安定した水素ガス濃度の水素ガスを体内に供給することができるガス供給装置及びガス供給方法を提供する。酸素含有ガスと水素ガスとを供給する人工呼吸器100であって、取り込まれた水素ガスを人工呼吸器100の外部へ送出する水素ガス送出部8と、水素ガス送出部8に取り込まれる水素ガスの量を調整する制御部22と、を備える。制御部22は、酸素含有ガスの流量に基づいて、水素ガス送出部8に取り込まれる水素ガスの量を調整する。
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公开(公告)号:WO2022137143A1
公开(公告)日:2022-06-30
申请号:PCT/IB2021/062153
申请日:2021-12-22
发明人: BURGESS, Aidan, Robert , PAYTON, Matthew, Jon , EDWARDS, Taylor, James , STEVEN, Brittany, Diana , WHITE, Craig, Karl , TULLETT, Sam, James , OXENBRIDGE, Mitchell, Ryan, Cammell , OSBORNE, Hamish, Adrian , OLDFIELD, Samantha, Dale , CHEUNG, Man, Kit, Jacky
摘要: The present disclosure relates to systems and apparatus that provide for integration of different respiratory therapies into a single system, or provide for integrated switching between separate systems or apparatuses delivering different therapies such as anaesthesia and high flow therapy. Aspects of the disclosure relate to various systems, devices, apparatuses, switching mechanisms and multi-lumen lumen assemblies for integrating control of these therapies and providing flexibility in how and where a user controls switching between therapies.
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公开(公告)号:WO2022105586A1
公开(公告)日:2022-05-27
申请号:PCT/CN2021/128001
申请日:2021-11-01
申请人: 深圳迈瑞生物医疗电子股份有限公司
摘要: 一种医疗设备系统以及通气治疗辅助设备,通气治疗辅助设备包括:参数获取装置,用于获取患者在通气治疗中的生理参数和通气参数;处理器,对患者当前通气策略下的通气治疗开始计时,根据计时得到通气治疗时间,以及生成氧合呼吸指数;以及将氧合呼吸指数与氧合呼吸指数阈值进行比对,获取氧合呼吸指数比对结果,将生理参数与生理参数阈值进行比对,获取生理参数比对结果,将通气参数与通气参数阈值进行比对,获取通气参数比对结果,根据氧合呼吸指数比对结果、生理参数比对结果和通气参数比对结果输出处置建议。
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公开(公告)号:WO2022055749A1
公开(公告)日:2022-03-17
申请号:PCT/US2021/048373
申请日:2021-08-31
申请人: KILJANEK, Lukasz, R.
发明人: KILJANEK, Lukasz, R.
摘要: Ventilator system with multiple inspiratory lumens is provided. The inspiratory lumens are configured so that separate inspiratory lumens provide inspiratory gas mixtures to separate portions of a patient's airways, for instance to separate lungs and/or bronchi. The ventilator system can include one or more expiratory lumens to evacuate expiratory gases from airways. The use of separate inspiratory lumen(s), with expiratory lumen(s), allows for functional separation of structural portions of the lungs, and maintenance of continuous or almost continuous flow through at least part of respiratory cycle via inspiratory and expiratory lumens. This can further reduce dead space and clear suspended therein diseases causative agents with improvement in outcomes, reduce risk of cross-contamination or cross-infection between different parts of airways, for example such as cross-infection from one lung lobe to another lobe or. The ventilator system allows for independent titration of PEEP, pCO2 and pO2 with no need for permissive hypercapnia.
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公开(公告)号:WO2022005555A1
公开(公告)日:2022-01-06
申请号:PCT/US2021/028011
申请日:2021-04-19
发明人: BELL, Adam D.
IPC分类号: A61M16/00 , A61M16/01 , A61M16/04 , A61B5/083 , A61M11/00 , A61M16/0003 , A61M16/0051 , A61M16/0063 , A61M16/024 , A61M16/0402 , A61M16/042 , A61M16/0427 , A61M16/0434 , A61M16/0465 , A61M16/0468 , A61M16/0486 , A61M16/0833 , A61M16/12 , A61M16/14 , A61M16/204 , A61M16/205 , A61M2016/0024 , A61M2016/0027 , A61M2016/0039 , A61M2016/0042 , A61M2202/0208 , A61M2202/0225 , A61M2202/0275 , A61M2202/0468 , A61M2205/18 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3382 , A61M2205/3386 , A61M2205/502 , A61M2205/505 , A61M2205/8206 , A61M2209/084 , A61M2210/1039 , A61M2230/432 , A61M2230/435
摘要: A method of, or system for, ventilating lungs in breathing and non-breathing patients--including applications for anesthesia--may comprise maintaining an inspiratory flow rate at an inspiratory setpoint at a low flow setting. Lung pressure in a patient may be regulated between a high pressure setpoint and a low pressure setpoint with periodic expiratory flows and continuous inspiratory flow. An expiratory control valve may be adjusted to an open position when a lung pressure is at or above a high pressure setpoint. An expiratory control valve may be adjusted to a closed position when a lung pressure is at or below a low pressure setpoint. Concurrent venting outflow and CO2 offloading through flow within the lungs may be facilitated by providing an intermittent expiratory flow to the patient while providing the continuous inspiratory flow.
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公开(公告)号:WO2021257352A1
公开(公告)日:2021-12-23
申请号:PCT/US2021/036705
申请日:2021-06-10
申请人: COVIDIEN LP
IPC分类号: A61M16/08 , A61M16/10 , A61M16/12 , A61M16/0087 , A61M16/0816 , A61M16/0875 , A61M16/0883 , A61M16/1005 , A61M16/125 , A61M16/202 , A61M2202/0208 , A61M2206/18
摘要: Aspects of the disclosure describe a design that isolates concentrated oxygen from electrical and/or flammable components of a ventilator. In an example, ventilator components containing or otherwise interacting with concentrated oxygen are isolated from the electrical equipment and/or drained to an exterior of the housing of the ventilator, in case of a leak. For example, an isolating structure encases the concentrated oxygen-carrying components to prevent concentrated oxygen from inadvertently leaking into the inside of the housing of the ventilator. The isolating structure may be a sleeve. An isolation gas inside the isolating structure may be fluidly coupled with ambient air outside the housing of the ventilator to allow the escape of isolation gas outside of the ventilator housing.
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公开(公告)号:WO2021242553A1
公开(公告)日:2021-12-02
申请号:PCT/US2021/032792
申请日:2021-05-17
申请人: LEGACY US INC.
IPC分类号: A61M16/12
摘要: An apparatus such as a fluid mixer, suitable for use with a respirator, including a venturi nozzle for flow of a pressure-controlled fluid; an ambient fluid aperture in fluid communication with the venturi nozzle; a fluid port; a pressure force multiplier in fluid communication with the fluid port; and a valve moveable relative to the venturi nozzle between a start flow position and a stop flow position; where the pressure force multiplier is configured such that fluid forced into the fluid port actuates the valve relative to the venturi nozzle; and where the pressure force multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle. A method of using an apparatus suitable for a ventilator is also disclosed.
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