公开(公告)号：WO2021148792A1

公开(公告)日：2021-07-29

申请号：PCT/GB2021/050132

申请日：2021-01-21

Applicant: OXFORD UNIVERSITY INNOVATION LIMITED

Inventor： GORINI, Giacomo

IPC: B01L7/02 ,  A61J1/16 ,  F25D23/00 ,  B01L2200/147 ,  B01L2300/04 ,  B01L2300/0861 ,  B01L2300/1844 ,  B01L2300/1894

Abstract: An apparatus (1) arranged to hold at least one vessel. The apparatus includes a frame (2) defining a gas flow pathway and having at least one aperture (6) configured to receive a vessel. The apparatus also includes a device (4) for directing a gas flow along the gas flow pathway, such that when a vessel is located in the aperture, the vessel is positioned at least partially in the gas flow pathway such that heat is transferred between the gas flow and the vessel.

公开(公告)号：WO2021146660A1

公开(公告)日：2021-07-22

申请号：PCT/US2021/013777

申请日：2021-01-16

Applicant: BIOLIFE SOLUTIONS INC.

Inventor： BRAUNSTEIN, Ryan ,  SCHRYVER, Brian

IPC: B60L7/00 ,  G01N1/28 ,  H05B1/02 ,  B01L2200/147 ,  B01L2300/123 ,  B01L2300/1827 ,  B01L3/505 ,  B01L7/5255

Abstract: A consistent and repeatable thawing method of frozen samples in a bag-format storage vessel is described herein. Methods and systems may allow for multiple bag-format storage vessel sizes to be used in the same device. A subset of a plurality of sensors may be qualified for the thawing method. The method may further include heating a frozen sample using a first heater bank and a second heater bank. In addition, the method may include measuring a plurality of second temperatures of the bag-format vessel. At or slightly after a second threshold temperature, the method may include heating using the first heater bank and terminating heating using the second heater bank. The method may include terminating the heating of the partially thawed sample using the first heater bank after the partially thawed sample has been heated using the first heater bank for a duration.

公开(公告)号：WO2022140174A2

公开(公告)日：2022-06-30

申请号：PCT/US2021/064009

申请日：2021-12-17

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： BEACHAM, Daniel W. ,  HINZ, Wolfgang ,  PARKER, Scott T. ,  DONOHUE, John

IPC: G01N27/414 ,  B01L3/00 ,  G01N33/487 ,  G01N35/00 ,  B01L2200/0668 ,  B01L2200/147 ,  B01L2300/027 ,  B01L2300/0663 ,  B01L2300/0829 ,  B01L2300/1827 ,  B01L2300/185 ,  B01L2300/1894 ,  B01L3/502715 ,  B01L7/00 ,  C12M1/00 ,  G01N15/00 ,  G02B21/00

Abstract: Systems, devices and methods for cell analysis provide an end user with real-time cell analysis and imaging of single cells in a population. Various cell analysis systems can provide both optical imaging, as well as electroscopic imaging, which is an image of cellular response as detected by sensors covering a cell footprint or cellular efflux. An automated fluidic system can provide an end-user selected sequence of reagents to cells, while precision controlled sensor array device thermostatting, and analysis compartment environmental control provide consistency in the cell analysis system environment.

公开(公告)号：WO2021245565A1

公开(公告)日：2021-12-09

申请号：PCT/IB2021/054825

申请日：2021-06-02

Applicant: NUCLEOLIFE LABORATORY (PTY) LTD ,  AGRICULTURAL RESEARCH COUNCIL

Inventor： DU TOIT, Daniel ,  VAN WYK, Petrus, Jacobus ,  VAN ROOYEN, Leunis ,  SWANEVELDER, Zacharias, Hendrik

IPC: B01L3/00 ,  B01L1/00 ,  G01N21/01 ,  B01L2200/147 ,  B01L2300/022 ,  B01L2300/023 ,  B01L2300/027 ,  B01L3/54 ,  G01N35/00

Abstract: The invention is for a point-of-care diagnostic device for detection of one or more biological targets of interest in a sample obtained from a patient and diagnosis of the patient, the device comprising: a reaction tube receiving chamber for receiving a single reaction tube that is associated with a radiofrequency identification (RFID) tag, the sample being received in the reaction tube and a biological reaction being conducted therein, when the reaction tube is received within the chamber; a sample sterilizer in communication with the reaction tube chamber configured to sterilize the sample by killing or deactivating microbes in the sample; a gesture sensor configured to receive a contactless user input from a user to initiate the biological reaction and obtain a diagnostic result of the sample; a thermal sensor for measuring and monitoring temperature of the sample during the biological reaction; an RFID reader configured to read the RFID tag associated with the reaction tube; a display screen configured to display the diagnostic result; and a wireless communication device configured to send the diagnostic result and patient data to another device. The invention also discloses a method of using the diagnostic device.

公开(公告)号：WO2021123803A1

公开(公告)日：2021-06-24

申请号：PCT/GB2020/053281

申请日：2020-12-18

Applicant: VIDYA HOLDINGS LTD

Inventor： VAN WORKUM, Stefan Leo ,  TUREK, Vladimir Alexander ,  DORRESTIJN, Marko ,  KLUG, David R.

IPC: G01N35/00 ,  B01L1/00 ,  B01L2200/04 ,  B01L2200/147 ,  B01L2300/023 ,  G01N2035/00306 ,  G01N2035/00356 ,  G01N2035/00455 ,  G01N35/00029 ,  G01N35/00732 ,  G01N35/0092

Abstract: A storage and incubation device is provided. The device is configured to accommodate a plurality of assay chips, each assay chip including a unique identifier. The device comprises: a plurality of berths each sized to accommodate an assay chip; a communication module configured to receive information about the identifier of each assay chip; a clock timer configured to monitor the timing of the assay within each assay chip; a completion module to manage each assay chip when the assay is complete.

公开(公告)号：WO2022269388A1

公开(公告)日：2022-12-29

申请号：PCT/IB2022/054922

申请日：2022-05-25

Applicant: PRECISION PLANTING LLC

Inventor： SWANSON, Todd ,  VACCARI, Adam ,  SCHAEFER, Timothy ,  LITWILLER, Riley

IPC: B01L3/00 ,  G01N33/24 ,  B01L2200/027 ,  B01L2200/147 ,  B01L2200/148 ,  B01L2300/0887 ,  B01L3/502715 ,  G01N2033/245

Abstract: An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi -concurrent manner. Advantageously, the system can process soil samples in the "as collected" condition without drying or grinding first to produce a sample slurry. The system includes a multi-layered microfluidic manifold chemical analysis substrate configured to provide a temperature- compensated concentration of analytes or other chemical properties associated with the sample. The system utilizes a programmable controller, temperature sensor, and absorbance measurement device for that purpose. The system can be used to analyze various type of agricultural-related samples including soil, vegetation, manure, milk or other.

公开(公告)号：WO2021262501A1

公开(公告)日：2021-12-30

申请号：PCT/US2021/037609

申请日：2021-06-16

Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.

Inventor： ZANTOS, George

IPC: B01L7/00 ,  G01N33/48 ,  B01L1/00 ,  B01L2200/147 ,  B01L2300/027 ,  B01L2300/1844 ,  B01L9/52

Abstract: A method and biological sample analyzer is described that adjusts airflow within a housing based upon altitude. A first volume of air is moved by at least one fan within a housing of a biological sample analyzer. A temperature of the first volume of air is measured within the biological sample analyzer with a temperature sensor within the housing of the biological sample. Power output of at least one heater positioned within the housing of the biological sample analyzer is measured. The measured power output of the at least one heater is analyzed at the measured temperature within the biological sample analyzer. And, the fan is adjusted to move a second volume of air different from the first volume of air by comparing the measured power output of the at least one heater and expected power output of the at least one heater.

公开(公告)号：WO2021198616A1

公开(公告)日：2021-10-07

申请号：PCT/FR2021/050567

申请日：2021-03-31

Applicant: LRX TECHNOLOGIES ,  LOOP DEE SCIENCE

Inventor： LEROUX, Thierry ,  ROCQUE, Louis-Marie

IPC: B01L7/00 ,  G01N21/64 ,  C12Q1/686 ,  B01L2200/147 ,  B01L2300/046 ,  B01L2300/0609 ,  B01L2300/0627 ,  B01L2300/0809 ,  B01L2300/0829 ,  B01L2300/0887 ,  B01L2300/1827 ,  B01L2300/1894 ,  B01L7/52 ,  C12Q1/6844 ,  G01N2021/6441 ,  G01N21/645

Abstract: Dispositif (100) de réalisation et lecture de la réaction d'amplification isotherme médiée par les boucles sur un échantillon à analyser reçu dans un tube de réaction (T).

公开(公告)号：WO2021123797A1

公开(公告)日：2021-06-24

申请号：PCT/GB2020/053271

申请日：2020-12-18

Applicant: VIDYA HOLDINGS LTD

Inventor： VAN WORKUM, Stefan Leo ,  TUREK, Vladimir Alexander ,  DORRESTIJN, Marko ,  KLUG, David R.

IPC: B01L3/00 ,  B01L2200/147 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/043 ,  B01L2300/0672 ,  B01L2300/123 ,  B01L2400/0478 ,  B01L2400/0481 ,  B01L2400/0683 ,  B01L3/502715

Abstract: A sample management module for receiving a fluid sample for an immunoassay is provided. The module comprises: a sample reception device for receiving a sample; a detection reagent; a controller configured to initiate a reaction timer on the basis of an actuation event when the sample and detection reagent are brought into contact.

公开(公告)号：WO2022155552A2

公开(公告)日：2022-07-21

申请号：PCT/US2022/012642

申请日：2022-01-15

Applicant: RAYTHEON BBN TECHNOLOGIES, CORP. ,  PURDUE RESEARCH FOUNDATION

Inventor： HORVATH, Dylan ,  MAN, Charlie ,  LOWE, Andrew ,  DEMPSTER, David ,  JAIN, Parth ,  ADLER, Aaron ,  BARTLEY, Bryan ,  DRYER, Paul ,  QUINN, Timothy ,  BAR-COHEN, Avram ,  GAVIN, Mike ,  SEVILLE, Jordan ,  MCCHESNEY, Darby ,  LADUCA, Frank M. ,  VERMA, Mohit

IPC: B01L3/00 ,  B01L7/00 ,  B01L9/00 ,  B01L2200/147 ,  B01L2200/16 ,  B01L2300/043 ,  B01L2300/0825 ,  B01L2300/1805 ,  B01L3/5023 ,  B01L7/52 ,  B01L9/527

Abstract: A liquid biological sample test cartridge is disclosed. The cartridge can include a tray. The cartridge can also include a chemical reaction pad supported by the tray. The cartridge can further include a chemical reaction pad cover disposed over the chemical reaction pad and coupled to the tray. The chemical reaction pad cover can have a sample opening to facilitate depositing a liquid biological sample at a predetermined location on the chemical reaction pad. In addition, the cartridge can include an outer cover operable to at least partially form an enclosure about the chemical reaction pad.