公开(公告)号：EP2204200B1

公开(公告)日：2018-11-14

申请号：EP10075024.9

申请日：2004-03-04

申请人： DePuy Mitek, LLC

发明人： CHUN, Iksoo ,  JAMIOLKOWSKI, Dennis D. ,  BROWN, Kelly R. ,  HWANG, Julia ,  BINETTE, Francois ,  MELICAN, Mora Carolynne

IPC分类号： A61L27/44 ,  A61L27/46 ,  A61L27/48 ,  A61L27/56

CPC分类号： A61F2/08 ,  A61F2210/0004 ,  A61L27/446 ,  A61L27/46 ,  A61L27/48 ,  A61L27/56 ,  A61L2430/34 ,  C08L67/04

摘要： A biocompatible tissue implant. The tissue implant may be bioabsorbable, and is made from a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a common solvent.

公开(公告)号：EP3389675A1

公开(公告)日：2018-10-24

申请号：EP16816664.3

申请日：2016-12-16

申请人： Vivacy International SA

发明人： DIACAKIS, Richard

IPC分类号： A61K31/728 ,  A61K9/00

CPC分类号： A61L27/20 ,  A61K9/0019 ,  A61K9/0034 ,  A61K9/06 ,  A61K31/728 ,  A61K47/36 ,  A61L2400/06 ,  A61L2430/34

摘要： The present invention relates to the field of penis enlargement and to hyaluronic acid compositions for use in the form of penile injections. It also relates to penoplasty using hyaluronic acid injection. It relates more particularly to a composition comprising at least one cross-linked hyaluronic acid, used in the treatment of locker-room syndrome and characterised in that it is administered in a dose of at least 0.15 ml/cm2, and in that said composition is administered repeatedly, with a first administration being followed by n subsequent administration(s) separated by a time interval of between 6 and 20 months, with n ≥ 1.

公开(公告)号：EP3365033A1

公开(公告)日：2018-08-29

申请号：EP16856477.1

申请日：2016-10-19

申请人： Skin Tissue Engineering Pty Ltd

发明人： GREENWOOD, John

IPC分类号： A61L27/00 ,  A61L27/44 ,  A61L27/52 ,  A61L27/56 ,  A61L27/58 ,  A61L2/00 ,  A61F2/10

CPC分类号： A61L27/3813 ,  A61L27/3687 ,  A61L27/44 ,  A61L27/52 ,  A61L27/56 ,  A61L27/58 ,  A61L27/60 ,  A61L2430/34 ,  A61L2430/40 ,  C08L2203/02 ,  C12M25/14 ,  C12N5/0062 ,  C12N2533/56 ,  G09B23/306

摘要： A method of incorporating cells in a porous matrix, the method comprising incorporating the cells in the porous matrix by forming a gel comprising the cells in situ in the porous matrix from a gellable medium, wherein the formation of the gel from the gellable medium comprises a time period of 10 minutes or less after contact of the gellable medium with the cells, thereby incorporating the cells in the porous matrix. The incorporated cells can then be used, for example, to produce a cultured skin product or deliver specific cells to a subject in need thereof.

公开(公告)号：EP3355948A1

公开(公告)日：2018-08-08

申请号：EP16852758.8

申请日：2016-09-30

申请人： Diluccio, Robert ,  Lorenc, Paul ,  Milby, Randy

发明人： Diluccio, Robert ,  Lorenc, Paul ,  Milby, Randy

IPC分类号： A61L27/58 ,  A61L27/54 ,  A61L27/38

CPC分类号： A61L27/58 ,  A61L27/20 ,  A61L27/3834 ,  A61L27/54 ,  A61L2300/404 ,  A61L2300/414 ,  A61L2300/43 ,  A61L2300/64 ,  A61L2400/06 ,  A61L2430/34 ,  C08L5/08

摘要： A therapeutic filler composition and method of using the same for augmenting soft tissue is provided. The therapeutic filler composition may include an anti-microbial first component, a carrier, and a cross-linking agent, wherein the carrier is cross-linked with the cross-linking agent and the first component is combined with the cross-linked carrier into a combination having a therapeutic effect.

公开(公告)号：EP3351257A1

公开(公告)日：2018-07-25

申请号：EP18154692.0

申请日：2014-03-14

申请人： MiMedx Group, Inc.

发明人： KOOB, Thomas J. ,  DENOZIERE, Guilhem ,  BROWN, Rebeccah J.C.

IPC分类号： A61K35/50 ,  A61L27/36

CPC分类号： A61L27/3604 ,  A61L27/3695 ,  A61L2400/06 ,  A61L2430/34

摘要： Described herein are molded dehydrated placental tissue compositions, and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the molded dehydrated placental tissue compositions are also described herein.

公开(公告)号：EP3346946A1

公开(公告)日：2018-07-18

申请号：EP16770142.4

申请日：2016-09-09

申请人： Lifecell Corporation

发明人： RINGO, Alexander

IPC分类号： A61F2/00 ,  A61L27/50

CPC分类号： A61L27/50 ,  A61F2/0063 ,  A61F2002/0081 ,  A61L27/362 ,  A61L27/3633 ,  A61L2430/04 ,  A61L2430/32 ,  A61L2430/34 ,  A61L2430/40

摘要： The present disclosure relates to tissue matrix products. The products can includes tissue matrices that have holes or perforations located at certain positions to improve certain in vivo functions without substantial loss of strength or other important properties.

公开(公告)号：EP3328351A1

公开(公告)日：2018-06-06

申请号：EP16739493.1

申请日：2016-07-18

申请人： Galderma S.A.

发明人： KARLSSON, Morgan ,  ÖHRLUND, Åke

IPC分类号： A61K8/73 ,  C08B37/08 ,  A61K31/728 ,  A61K47/36 ,  C08L5/08

CPC分类号： C08J3/24 ,  A61K8/735 ,  A61K9/06 ,  A61K31/728 ,  A61K47/36 ,  A61K2800/91 ,  A61L27/20 ,  A61L2430/34 ,  A61Q19/08 ,  C08B37/0072 ,  C08J3/075 ,  C08J2305/08 ,  C08L5/08 ,  C08L2201/54 ,  C08L2203/02

摘要： A process for manufacturing a cross-linked hyaluronic acid (HA) gel product is comprising the steps of: (a) preparing an aqueous mixture of HA and a cross-linking agent selected from multiepoxides and diepoxides; wherein the HA is dissolved in an aqueous solution containing 1-10% (w/w) inorganic hydroxide; and wherein the dissolved HA constitutes more than 10% (w/w) of the final mixture; and (b) subjecting the aqueous mixture to cross-linking conditions to allow the dissolved HA to react with the cross-linking agent so as to obtain a cross-linked HA gel product.

公开(公告)号：EP3325034A1

公开(公告)日：2018-05-30

申请号：EP16831118.1

申请日：2016-07-22

申请人： Teleflex Medical Incorporated

发明人： GUPTA, Nisha ,  GIARE-PATEL, Kamna ,  YOU, Chuanting

IPC分类号： A61L33/00 ,  B05D3/00

CPC分类号： A61L31/16 ,  A61L27/18 ,  A61L27/28 ,  A61L27/34 ,  A61L27/54 ,  A61L31/06 ,  A61L31/08 ,  A61L31/10 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/602 ,  A61L2300/606 ,  A61L2420/06 ,  A61L2430/02 ,  A61L2430/34

摘要： An implantable orthopedic device having an antimicrobial coating on at least one surface thereof is disclosed. The antimicrobial coating includes alexidine and a carrier polymer.

公开(公告)号：EP3311826A1

公开(公告)日：2018-04-25

申请号：EP17190524.3

申请日：2012-02-13

申请人： MiMedx Group, Inc.

发明人： MORSE, Brenda S. ,  SITH, Somaly ,  SPENCER, Randall ,  RAY, Steven ,  DANIEL, John ,  TOFE, Robert

IPC分类号： A61K35/50 ,  A61L27/36 ,  A61Q19/00 ,  A61P17/02 ,  A61K8/98

CPC分类号： A61K35/50 ,  A61K8/982 ,  A61K35/12 ,  A61L27/3604 ,  A61L27/3683 ,  A61L27/3695 ,  A61L2400/06 ,  A61L2430/34 ,  A61P17/02 ,  A61Q19/00

摘要： Described herein are composition composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.

摘要翻译： 本文描述了由微粉化胎盘组分和其药物组合物组成的组合物。 该组合物具有许多医学应用。 本文还描述了制造和使用微粉化组合物的方法。

公开(公告)号：EP2433492B1

公开(公告)日：2018-04-25

申请号：EP11186264.5

申请日：2005-03-17

申请人： Revivicor Inc.

发明人： Ayares, David ,  Rohricht, Paul

IPC分类号： A01K67/00 ,  A61F2/02 ,  A61F2/08 ,  A61F2/10 ,  A61F2/28 ,  A61L27/36

CPC分类号： A61L27/3683 ,  A01K67/0276 ,  A01K2217/075 ,  A01K2227/108 ,  A01K2267/02 ,  A01K2267/025 ,  A61K35/12 ,  A61L27/3604 ,  A61L27/3629 ,  A61L27/3641 ,  A61L27/3695 ,  A61L2430/34 ,  C12N9/1051 ,  C12N15/8509

摘要： The present invention provides tissues derived from animals, which lack any expression of functional alpha 1,3 galactosyltransferase (alpha-1,3-GT). Such tissues can be used in the field of xenotransplantation, such as orthopedic reconstruction and repair, skin repair and internal tissue repair or as medical devices.