公开(公告)号：EP2331882A2

公开(公告)日：2011-06-15

申请号：EP09819545.6

申请日：2009-10-06

申请人： Sunnovations Inc.

发明人： VAN HOUTEN, Arnoud

IPC分类号： F24J2/04 ,  F24D15/00 ,  F24J2/24 ,  F24J2/30

CPC分类号： F28D20/0039 ,  F24D17/0021 ,  F24D19/0092 ,  F24D19/1057 ,  F24D2200/14 ,  F24D2220/06 ,  F24D2220/08 ,  F24D2240/10 ,  F24D2240/12 ,  F24S40/50 ,  F24S40/58 ,  F24S40/60 ,  F24S90/10 ,  F28D2020/0069 ,  F28D2020/0078 ,  Y02B10/20 ,  Y02E10/40 ,  Y02E60/142 ,  Y02E70/30

摘要： Solar collectors heat and self pump heat transfer fluid at reduced system pressure without mechanical intervention for heat exchange with hot water in a storage tank. Slugs of hot fluid are pumped by steam bubbles formed in solar collector tubes through an upper manifold and an exit-tube into an upper hot fluid reservoir. Hot fluid flows downward through a heat exchanger at the tank. Cold fluid returns to a lower reservoir. Vapor flows from the upper reservoir and is condensed by cooler water and walls of the lower reservoir. The cool fluid returns from the lower reservoir to a lower manifold supplying the collector tubes. Below ambient pressure is automatically established in the system. When heat build-up increases pressure in the system, fluid flows to a third closed variable volume reservoir. A float valve in the bottom of the third reservoir allows liquid to return to the system when it cools.

公开(公告)号：EP1728507B1

公开(公告)日：2011-03-16

申请号：EP06076172.3

申请日：2006-06-06

申请人： NattoPharma ASA

发明人： Vermeer, Cees

IPC分类号： A61K31/122 ,  A61K31/593 ,  A23L1/302 ,  A23L1/303 ,  A61P9/10

CPC分类号： A61K31/593 ,  A23L33/15 ,  A23L33/155 ,  A23V2002/00 ,  A61K31/122 ,  A61K2300/00 ,  A23V2250/71 ,  A23V2200/326

公开(公告)号：EP2087131A1

公开(公告)日：2009-08-12

申请号：EP07819552.6

申请日：2007-11-02

申请人： Thrombinoscope B.V.

发明人： GIESEN, Peter L., A. ,  TAPPENDEN, Kerry ,  JONES, Wynne

IPC分类号： C12Q1/37 ,  C12Q1/56

CPC分类号： C12Q1/37 ,  C12Q1/56

摘要： A method is provided for determining in real time the course of thrombin activity in a sample of clotting blood or plasma as it appears in and disappears from the sample which comprises adding a signal substrate to said sample, said signal substrate causing a detectable signal related to the amount of conversion product formed upon reaction by the generated proteolytic activity, monitoring the signal development in time in said sample to provide a curve, and mixing said sample frequently so that clot formation occurs in a dense manner such that the majority of the sample remains fluid and that cell precipitation is inhibited, wherein said monitoring and mixing steps are repeated and performed in an alternate way.

公开(公告)号：EP1513411B1

公开(公告)日：2008-05-14

申请号：EP03755973.9

申请日：2003-06-02

申请人： CSK Food Enrichment B.V.

发明人： VAN BOVEN, A., c/o CSK Food Enrichment B.V. ,  LAUTENBACH, S., c/o CSK Food Enrichment B.V. ,  KOOPMANS, W.J., c/o CSK Food Enrichment B.V. ,  KEVELAM, J., c/o CSK Food Enrichment B.V.

IPC分类号： A23C19/16 ,  A23L1/00

CPC分类号： A22C13/0013 ,  A23C19/163 ,  A23P20/19

摘要： Cheese coatings are provided comprising a copolymer with vinyl acetate and ethylene as the prevalent monomer constituents, which have significantly lower water vapour permeability as compared with the state of the art, thus allowing the production of cheese having a relatively high water content, whilst the quality of the cheese, in particular of the taste, is not adversely affected. Advantages of the present invention include improved texture of reduced fat cheese and the possibility to store cheese under conditions at lower relative humidity (i.e. having less risk of microbial growth on the exterior of the cheese) whilst keeping the moisture loss to an acceptable value.

公开(公告)号：EP1504269B1

公开(公告)日：2007-07-25

申请号：EP03747454.1

申请日：2003-05-01

申请人： Synapse B.V.

发明人： Giesen, Peter, Synapse B.V. ,  Hemker, Hendrick C., Synapse B.V. ,  Al Dieri, Raed, Synapse B.V. ,  Beguin, Suzette L., Synapse B.V. ,  Wagenvoord, Robert, Synapse B.V.

IPC分类号： G01N33/86 ,  C12Q1/56

CPC分类号： G01N33/86 ,  C12Q1/56

摘要： A method is provided for determining in real time the course of thrombin activity in a sample of blood or plasma as it appears in and disappears from the sample which comprises adding a thrombin substrate to the sample that, per unit time, produces a detectable signal in a quantity that bears relation to the amount of thrombin present. Simultaneously, in a control sample of the same blood or plasma in which thrombin generation is not triggered, the activity of a standard preparation with invariable thrombin activity is measured. The exact molar amount of thrombin present at any moment is obtained by comparison of the activity measured in clotting blood and the simultaneously measured calibrator. The method is useful inter alia for diagnosing hyper- and hypo-coaguable states, either congenital, acquired or drug-induced in humans and animals. Also provided is a kit for use in this method.

公开(公告)号：EP1153548B1

公开(公告)日：2007-05-02

申请号：EP01201431.2

申请日：2001-04-20

申请人： Vitak B.V.

发明人： Quinlan, Paul Thomas, Unilever Res. Vlaardingen

IPC分类号： A23L1/302 ,  A23L1/30 ,  A23L1/29 ,  A23L1/24 ,  A23L1/39 ,  A23L1/10 ,  A23L1/304 ,  A23L2/52 ,  A23D7/00 ,  A23D9/00 ,  A61K31/12 ,  A61K39/39 ,  A61K9/10

CPC分类号： A61K31/122 ,  A23D7/0056 ,  A23F3/14 ,  A23F3/163 ,  A23G1/426 ,  A23G9/366 ,  A23L2/52 ,  A23L7/101 ,  A23L27/60 ,  A23L33/15 ,  A23L33/16 ,  A23V2002/00 ,  A61K31/12 ,  A23V2250/154 ,  A23V2250/5432 ,  A23V2250/628 ,  A23V2250/61 ,  A23V2250/5424 ,  A23V2250/18 ,  A23V2250/714 ,  A23V2200/222 ,  A23V2250/7144 ,  A23V2250/161 ,  A23V2250/1578 ,  A23V2250/71

公开(公告)号：EP1763588A1

公开(公告)日：2007-03-21

申请号：EP05771213.5

申请日：2005-05-30

申请人： Universiteit van Maastricht

发明人： PLAT, Jogchum ,  MENSINK, Ronald P.

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/156

摘要： The present invention provides the use of at least one genotype selected from the group consisting of ABCG8 T400K and ABCG8 D19H as a diagnostic tool for the detection of an increased risk for coronary events in an individual based on an elevated sitosterol concentration in a blood sample from said individual.

公开(公告)号：EP1642504A1

公开(公告)日：2006-04-05

申请号：EP04077674.2

申请日：2004-09-29

申请人： CSK Food Enrichment B.V.

发明人： Kevelam, Jan ,  Koopmans, Wieger J. ,  Meijer, Wilco

IPC分类号： A23C19/16 ,  A23L1/00

CPC分类号： A23C19/16

摘要： The present invention provides a new composition for coating food and food ingredients, in particular cheese, and the use of such a composition. More in particular, a protective cheese coating is provided involving certain hydrophilic polymers as additives, allowing an improved adhesion of an outer layer of cheese wax ("paraffin"). These hydrophilic polymers are selected from the group consisting of hydrophilic polymers such as caseins, starches, modified starches, cellulose derivatives such as cellulose ethers, alginates, naturally occurring gums, such as gum arabic, fermentation produced polysaccharides such as xanthan gum. Preferred additives are carboxymethyl cellulose, hydroxyethyl cellulose, arabic gum, amylogum, starch and derivatives thereof, and casein.

摘要翻译： 本发明提供了用于涂覆食品和食品成分，特别是奶酪的新组合物，以及这种组合物的用途。 更具体地，提供了保护性乳酪涂层，其涉及某些亲水性聚合物作为添加剂，允许改进的奶酪蜡外层（“石蜡”）的附着力。 这些亲水性聚合物选自亲水性聚合物如酪蛋白，淀粉，改性淀粉，纤维素衍生物如纤维素醚，藻酸盐，天然存在的树胶如阿拉伯树胶，发酵产生的多糖如黄原胶。 优选的添加剂是羧甲基纤维素，羟乙基纤维素，阿拉伯树胶，淀粉，淀粉及其衍生物和酪蛋白。

公开(公告)号：EP1576174A2

公开(公告)日：2005-09-21

申请号：EP03767088.2

申请日：2003-08-01

申请人： Orchid BioSciences, Inc.

发明人： MCKEOWN, Brian ,  DERBYSHIRE, Roger ,  ROWAN, Paul ,  SUNG, Robert

IPC分类号： C12Q1/00

CPC分类号： C12Q1/6858 ,  C12Q2545/101 ,  C12Q2525/155

摘要： The invention provides compositions and methods for performing primer extension reactions, including employment of amplification primers having 5' tags to incorporate into amplicons variant nucleotides of interest from target nucleic acids at known ratios, with or without sequences surrounding the variant nucleotides of interest. The invention provides identifying the variant nucleotides generated from the target nucleic acid and generated from the 5' tags, comparing the results, evaluating the efficiency of the primer extension reactions, and monitoring the efficacy of such reactions. The invention accounts for DNA sequence and experimental variables that may affect efficiency of incorporation of nucleotides, and provides a reference point for the interpretation of polymorphisms. The invention also provides methods of breeding scrapie-resistant sheep populations.

公开(公告)号：EP1556025A1

公开(公告)日：2005-07-27

申请号：EP03790959.5

申请日：2003-09-01

申请人： VITAK BV

发明人： VERMEER, Cees,Vitak BV

IPC分类号： A61K31/122 ,  A61K31/593 ,  A61P9/04 ,  A61P9/10 ,  A61P9/12 ,  A61P9/14

CPC分类号： A61K31/122 ,  A23L2/52 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23V2002/00 ,  A61K31/12 ,  A61K31/59 ,  A61K31/593 ,  A61K45/06 ,  A61K2300/00 ,  A23V2250/1578 ,  A23V2250/1642 ,  A23V2250/161 ,  A23V2250/7106 ,  A23V2250/7142

摘要： Vitamin K is effective in counteracting the reduction in arterial elasticity normally associated with the aging process. A pharmaceutical composition or nutritional formulation comprising vitamin K can be used to combat age-related stiffening of the arteries, and the consequences thereof, namely pulmonary congestion, hypertension, left ventricular hypertrophy, congestive (right sided) heart failure, left sided or left ventricular failure, chronic cardiac failure, angina pectoris, myocardial infarction, Mönckeberg's sclerosis and stroke.