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公开(公告)号：EP0602237A4
公开(公告)日：1996-01-17
申请号：EP93916824
申请日：1993-06-29
申请人： UNIV GEORGIA RES FOUND , AMGEN INC
IPC分类号： A61K39/395 , C07K7/06 , C07K7/08 , C12N1/21 , C12N5/10 , C12N9/10 , C12N15/00 , C12N15/54 , C12R1/19 , C12R1/91 , G01N33/53 , C07H21/04 , C12N15/70 , C12N15/74 , C12N15/79 , C12P21/02
CPC分类号： C12N9/1051
摘要： The present invention provides a substantially purified UDP-N-acetylglucosamine:α-6-D-mannoside β-1,6-N-acetylglucosaminyltransferase (GlcNAc T-V; EC 2.4.1.155) and antibodies which specifically bind GlcNAc T-V. The present invention also provides polynucleotide sequences and oligonucleotide probes capable of specifically hybridizing to nucleic acid sequences which encode GlcNAc T-V, and cDNA and genomic clones encoding GlcNAc T-V, as well as nucleotide sequences encoding GlcNAc T-V, as specifically exemplified by a GlcNAc T-V coding sequence from rat.
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公开(公告)号：EP2007803A4
公开(公告)日：2009-12-09
申请号：EP07751151
申请日：2007-02-20
发明人： IVARIE ROBERT D , LIU GUODONG , RAPP JEFFREY C , MORRIS JULIE A , HARVEY ALEX J
IPC分类号： C07K14/535
CPC分类号： C07K14/535
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公开(公告)号：EP1799029A4
公开(公告)日：2008-08-27
申请号：EP05815479
申请日：2005-10-13
发明人： HUSSEY RICHARD S , HUANG GUOZHONG
IPC分类号： A01H5/02 , C07K14/435 , C12N15/82
CPC分类号： C12N15/8285 , C07K14/43563 , C12N15/8218 , Y02A40/164
摘要： Compositions and methods for providing nematode resistance are provided. One aspect provides transgenic plants or cells comprising an inhibitory nucleic acid specific for one or more nematode esophageal polypeptides. Other aspects provide transgenic plants or cells resistant to at least two different root-knot nematode species.
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14.发明公开MEDICAL COMPOSITIONS, DRESSINGS AND METHODS FOR TREATING MICROBIAL INFECTIONS OF SKIN LESIONS 有权医药组合物协会和皮损的治疗微生物感染的方法
公开(公告)号：EP1330221A4
公开(公告)日：2007-10-24
申请号：EP01973127
申请日：2001-09-19
发明人： WOOLEY RICHARD E , RITCHIE B W
CPC分类号： A61K45/06 , A61K9/0014 , A61K9/70 , A61K47/183 , A61K47/186
摘要： The present invention relates to methods of inhibiting the proliferation of a microbial population of a surface lesion of a human or animal, wherein the lesion is contacted with an antimicrobial composition comprising a pharmaceutically acceptable antibiotic, a pharmaceutically acceptable chelating agent and a pharmaceutically acceptable pH buffering agent (Fig. 1). Another aspect of the present invention is a medical dressing for delivering an antimicrobial composition to a site of a skin injury or lesion of a mammal, comprising a support and an antimicrobial agent and at least one chelating agent. The present invention also relates to methods for delivering an antibiotic to an injury to the skin of a human o animal and to kits for the preparation and use of an antimicrobial comosition to inhibit a microbial infection of a skin injury or lesion of a human or animal.
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15.发明公开
公开(公告)号：EP1534068A4
公开(公告)日：2006-08-23
申请号：EP03785049
申请日：2003-08-08
CPC分类号： C12N5/0618 , A61K35/12 , C12N5/0619 , C12N2500/32 , C12N2500/90 , C12N2501/115 , C12N2501/91 , C12N2502/13 , C12N2506/02
摘要： The present invention provides compositions and methods for human neural cell production. More particularly, the present invention provides cellular differentiation methods employing an essentially serum free MEDII conditioned medium for the generation of human neural cells from pluripotent and multipotent human stem cells.
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公开(公告)号：EP1569687A4
公开(公告)日：2006-02-15
申请号：EP03796784
申请日：2003-12-08
IPC分类号： A61K39/012 , A61K39/00 , A61K39/35 , C12P21/06
CPC分类号： A61K39/012 , A61K2039/522 , A61K2039/542
摘要： The present invention relates to a vaccine for coccidiosis in chickens prepared from four attenuated Eimeria species: E. acervulina, E. maxima, E. mitis and E. tenella. The vaccine was similar to or superior to other anticoccidial drugs in stimulating protective immunity against coccidiosis.
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公开(公告)号：EP0826037A4
公开(公告)日：2000-08-09
申请号：EP96920297
申请日：1996-05-17
发明人： LI XIN-LIANG , LJUNGDAHL LARS G , CHEN HUIZHONG
CPC分类号： C12N9/2482 , C07K2319/00 , C07K2319/02 , C12Y302/01008
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18.发明公开L-$g(b)-DIOXOLANE URIDINE ANALOGS AND METHODS FOR TREATING AND PREVENTING VIRUS INFECTIONS 失效BETA-L-DIOXOLANURIDIN模拟和方法用于治疗和病毒感染的预防
公开(公告)号：EP0956021A4
公开(公告)日：2000-06-28
申请号：EP97947480
申请日：1997-11-14
申请人： UNIV YALE , UNIV GEORGIA RES FOUND
发明人： CHENG YUNG-CHI , CHU CHUNG K , QU FUCHENG
IPC分类号： A61K31/506 , A61P31/12 , A61P35/00 , A61P37/00 , C07D405/04 , C07F9/6558 , A61K31/505 , A61P31/18 , A61P31/22 , C07H19/10
CPC分类号： C07D405/04
摘要： The present invention relates to the discovery that certain β-L-dioxolane nucleoside analogs which contain a uracil base, and preferably, a 5-halosubstituted uracil base, exhibit unexpectedly high activity against Epstein-Barr virus (EBV), Varicella-Zoster virus (VZV) and Human Herpes Virus 8 (HV-8). In particular, the compounds according to the present invention show potent inhibition of the replication of the virus (viral growth) in combination with very low toxicity to the host cells (i.e., animal or human tissue). Compounds are useful for treating EBV, VZV and HV-8 infections in humans.
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19.发明公开A NOVEL FAMILY OF POLLEN PROTEINASES, METHODS OF USE THEREOF AND COMPOSITIONS DERIVED THEREFROM 失效POLLENPROTEINASEN新系列，其使用方法和衍生组合
公开(公告)号：EP0705435A4
公开(公告)日：1997-11-26
申请号：EP94921321
申请日：1994-06-17
发明人： TRAVIS JAMES , BARR PHILIP J
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20.发明公开L-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B-VIRUS AND EPSTEIN-BAR VIRUS 失效L-核苷对乙型肝炎的治疗和爱泼斯坦 - BAR VIRUS
公开(公告)号：EP0748330A4
公开(公告)日：1997-03-19
申请号：EP95909404
申请日：1995-01-30
申请人： UNIV GEORGIA RES FOUND , UNIV YALE
发明人： CHU CHUNG K , CHENG YUNG-CHI , PAI BALAKRISHNA S , YAO GANG-QING
IPC分类号： C07H19/09 , A61K31/70 , A61K31/7042 , A61K31/7052 , A61K31/7064 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61P31/12 , C07H19/00 , C07H19/06 , C07H19/16 , C07H19/19 , C07H19/20 , C07H21/00
CPC分类号： C07H19/06 , C07H19/16 , C07H21/00 , Y10S514/893 , Y10S514/894 , Y10S514/931 , Y10S514/934
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