摘要:
Lageranlage ( 15 ) und Lagerbehältnis ( 10 ) für Objekte ( 1 ). Die Lageranlage ( 15 ) besitzt eine Lagervorrichtung ( 14 ) mit mindestens einem Lagerschacht ( 14.1, 14.2 ), der mehrere übereinander angeordnete Lagerstellen ( 13) enthält, und eine Übergabestelle ( 34 ) zur kurzzeitigen Aufnahme der Objekte ( 1 ). Die Lageranlage ( 15 ) besitzt ferner eine Transporteinrichtung ( 16 ) mit einem Objektträger ( 36 ), welche eine Vertikal-Verschiebevorrichtung ( 40 ), eine Horizontal-Drehvorrichtung ( 38 ) und eine Horizontal-Verschiebevorrichtung ( 42 ) aufweist, um den Objektträger ( 36 ) zwischen der Übergabestelle ( 34 ) und den Lagerstellen ( 13 ) zu verschieben. nehmen, wobei vorzugsweise eine Grundfläche der Objekte horizontal gerichtet ist. Die Objekte ( 1 ) nehmen stets denselben Winkel zur Vertikalen ein. Der Objektträger ( 36 ) ist höchstens unwesentlich grösser als die Objekte ( 1 ). Das Lagerbehältnis ( 10 ) besteht aus einem Lagerschrank ( 12 ) und einer integrierten Lageranlage ( 15 ). Der Lagerschrank weist eine Schleusenfensteröffnung auf, deren Abmessungen den Abmessungen eines Objektes ( 1 ) entsprechen. Die Übergabestelle ( 34 ) befindet sich ausserhalb des Lagerschrankes ( 12 ).
摘要:
The apparatus has two main regions of members the operation of which is controlled separately, the first region, to which the user has interactive access, permitting loading of the samples, controls, calibrators, diluents and other equipment for performing the sampling and dilutions and receiving the plate on which the tests are performed, and the second region, to which the user has occasional access, comprising stations dedicated to the rest of the process including incubation, washing, reading, and others, the second region being able to hold several plates at different stages of the process, the apparatus having means for automated movement along three coordinate axes X, Y, Z in order to transport the reagents and the plates in order to complete the process, enabling several tests to be performed at the same time on a set of samples in one or several plates, and enabling new series of tasks with the same or different sets of tests and with the same or different sets of samples to be started when the previous ones have not been completed, the apparatus comprising, beneath its two main regions of members, a series of containers for the storage of the auxiliary liquids of the process and for the collection of washings and waste.
摘要:
A method in which a temperature is generated across a gradient block, and an apparatus comprising a block (2, 17, 18, 19) across which a temperature gradient can be generated. By setting up such a gradient, multiple reaction mixtures held in wells (3) on the gradient block (2, 17, 18, 19) can be simultaneously run at temperatures which differ only slightly, thereby permitting an optimum temperature for the reaction to be quickly identified. In a preferred embodiment, the gradient block (2, 17, 18, 19) is integrated into a thermal cycler used for nucleic acid amplification reactions.
摘要:
Monitoring apparatus comprises support means (1008) for receiving a plurality of items (602) to be monitored in an array, each item having a unique machine-readable identifiying reference (616) associated therewith, the arrangement being such that the items are movable to different positions in the array; sensor means (1024) for intermittenlty and repeatedly monitoring each item in the array to monitor changes in a variable associated with each item and to read the reference associated with each item; means for supplying data to the monitored variable and machine-readable reference of each item to computer means (1004), wherein the computer means relates the monitored variable to the reference to each item independently of the position of the item in the array.
摘要:
Appareil assurant le transfert d'une cartouche de réaction (10) vers différentes zones de traitement (36, 38, 42). Des dispositifs automatiques (34, 40) assurent le transfert de la cartouche de réaction vers différentes zones de l'appareil (30, 32, 36, 38, 42, 46). Un dispositif de formation d'image (42) détecte des images indiquant si telle réaction s'est produite dans tel puits de réaction (16) de la cartouche de réaction (10). L'appareil comporte également un dispositif (36) d'aspiration et de distribution des liquides assorti d'un sytème de détection du niveau de liquide (70, 72, 74, 76, 78, 80, 82, 84). L'appareil comporte en outre un micro-processeur et une logique (44) de contrôle de fonctionnement et d'analyse des informations reçues du dispositif de formation d'image (42) afin de produire une indication visuelle des résultats des analyses.
摘要:
An apparatus for carrying out an enzymatic cycling reaction including a turntable (3) arranged in a reaction tank (1), a number of reaction vessels (2) being arranged in the turntable along its periphery, a device (6, 7) for circulating an antifreeze liquid through the reaction tank (1), a heater (9) for heating the antifreeze liquid, a refrigerator (10), for cooling the antifreeze liquid and a switching valve (8) for selectively passing the antifreeze liquid through the heater (9) or refrigerator (10). Until all the samples and cycling mixture are delivered into the reaction vessels, the reaction tank (1) is held at a very low temperature at which no enzymatic cycling reaction proceeds. Then the antifreeze liquid is heated to an enzymatic cycling reaction temperature so as to perform the enzymatic cycling reaction simultaneously for liquids contained in all the reaction vessels for a desired period. Then, the antifreeze liquid is heated to a high temperature so as to stop simultaneously the cycling reaction in all the reaction vessels.
摘要:
A multi-well plate (1910) having an array of wells, wherein said array corresponds to a 96-well plate or 384-well plate configuration comprising one or more sectors (1910A,1910B,1910C) having wells. Said multi-well plate (1910) having a plurality of electrodes on a top surface and a plurality of contact surfaces on a bottom surface, wherein said plurality of electrodes are electrically connected to said plurality of contact surfaces. A kit for use in the conduct of an ECL assay comprising in one or more containers, the multi-well plate (1910) and at least one ECL label.