公开(公告)号：EP2855676A2

公开(公告)日：2015-04-08

申请号：EP13798228.6

申请日：2013-05-30

申请人： University Of Utah Research Foundation

发明人： HUGHES, Kelly, T. ,  OLIVERA, Baldomero, M.

IPC分类号： C12N15/04

CPC分类号： C07K14/245 ,  C07K14/255 ,  C07K14/34 ,  C07K14/43504 ,  C07K14/43518 ,  C07K14/43522 ,  C07K14/46 ,  C07K2319/036 ,  C07K2319/21 ,  C07K2319/50 ,  C12N15/62 ,  C12N15/70 ,  C12N15/74 ,  C12P21/02

摘要： Disclosed are compositions and methods for expressing and purifying a peptide of interest using a Flagellar Type III secretion system. Disclosed are nucleic acid sequences that contain a FlgM nucleic acid sequence, a cleavage site, and a nucleic acid sequence of interest. Also disclosed are polypeptides that contain FlgM, a cleavage site and a peptide of interest. Methods of producing polypeptides that have FlgM, a cleavage site and a peptide of interest are provided.

摘要翻译： 公开了使用鞭毛III型分泌系统表达和纯化目标肽的组合物和方法。 公开了含有FlgM核酸序列，切割位点和感兴趣的核酸序列的核酸序列。 还公开了含有FlgM，切割位点和目的肽的多肽。 提供了产生具有FlgM，切割位点和目的肽的多肽的方法。

公开(公告)号：EP2635690A1

公开(公告)日：2013-09-11

申请号：EP11838704.2

申请日：2011-11-01

申请人： Codexis, Inc.

发明人： DHAWAN, Ish, Kumar ,  BAIDYAROY, Dipnath ,  SHAW, Andrew ,  TANCHAK, Oleh ,  HILL, Christopher ,  LIU, Chengsong ,  CHOKSHI, Amala ,  SCOTT, Brian, R.

IPC分类号： C12P7/10 ,  C12N9/02 ,  C12N15/04

CPC分类号： C12P19/14 ,  C12N9/0006 ,  C12N9/2437 ,  C12P7/10 ,  C12P19/02 ,  C12P19/12 ,  C12P2203/00 ,  C12Y101/99018 ,  C13K1/02 ,  Y02E50/16

摘要： The present application provides genetically modified fungal organisms that produce enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to glucose, enzyme mixtures produced by the genetically modified fungal organisms, and processes for producing glucose from cellulose using such enzyme mixtures.

公开(公告)号：EP2507358A2

公开(公告)日：2012-10-10

申请号：EP09706403.4

申请日：2009-03-30

申请人： Proenol Industria Biotecnologica, Lda ,  Universidade do Minho

发明人： RAPOSO MONTEIRO DOS SANTOS, Júlia Margarida ,  MARQUES FERREIRA DE SOUSA MOREIRA, Maria João ,  DE LEMOS PINTO ESTRELA LEÃO, Maria Cecília ,  TEIXEIRA CARDOSO DA SILVA, Maria de Fátima ,  TEIXEIRA DA SILVA, Sofia Beatriz ,  MONTEIRO CENTENO DA COSTA, Filipe Miguel

IPC分类号： C12N1/16 ,  C12P7/04 ,  C12P39/00 ,  C12G1/00 ,  C12N15/04 ,  C12R1/865

CPC分类号： C12N1/16 ,  C12G1/0203 ,  C12G2200/11 ,  C12N15/04 ,  C12P7/04 ,  C12P39/00 ,  C12R1/865

摘要： This invention relates to a process of obtaining hybrid strains obtained by protoplast fusion of Saccharomyces cerevisiae and Torulaspora delbrueckii and their use in fully conducting alcoholic fermentations of red and white wine as well as their use as restarter strains in the rectification of stuck or sluggish fermentations. This new strains combine characteristics of both parental strains, namely the sugar consumption displayed by S. cerevisiae, intermediate ethanol resistance of the one displayed by parental strains and aromatic profile similar to T. delbrueckii. This invention further refers to the three strains obtained as well as to the consortium of the three.

摘要翻译： 本发明涉及获得由酿酒酵母的原生质体融合和孢圆酵母德氏及其在完全导通的红，白葡萄酒酒精发酵以及它们作为在卡住或呆滞发酵整流重新启动器菌株使用使用获得杂交菌株的方法。 此新菌株结合这两个亲本菌株，即糖消耗由酿酒酵母中，一个通过类似于T.德氏亲本菌株和芳族简档显示的中间耐乙醇性显示的特性。 本发明还涉及这三个菌株中获得，以及三个财团。

公开(公告)号：EP2041280A4

公开(公告)日：2009-12-02

申请号：EP06768960

申请日：2006-06-20

申请人： MOGAM BIOTECH RES INST

发明人： LIM HYUNG-KWON ,  KIM SUNG-GEUN

IPC分类号： C12N15/10 ,  C12N9/38 ,  C12N15/04

CPC分类号： C12N15/81

公开(公告)号：EP1766007A4

公开(公告)日：2008-03-12

申请号：EP05746690

申请日：2005-06-08

申请人： MICROBIOGEN PTY LTD

发明人： BELL PHILIP JOHN LIVINGSTONE ,  ATTFIELD PAUL VICTOR

IPC分类号： C12N15/04 ,  C12N1/18 ,  C12N15/01 ,  C12P7/06 ,  C12R1/865

CPC分类号： C12N15/81 ,  C12N1/18 ,  C12N15/01 ,  C12P7/06 ,  C12R1/85 ,  C12R1/865 ,  Y02E50/17

公开(公告)号：EP0938545B1

公开(公告)日：2004-08-11

申请号：EP97931506.6

申请日：1997-06-30

申请人： UNIVERSITY OF HAWAII

发明人： STUART, W., Dorsey

IPC分类号： C12N15/04 ,  C12N15/10 ,  G01N33/53

CPC分类号： C40B40/02 ,  C07K14/59 ,  C12N15/04 ,  C12N15/1037

摘要： The present invention provides methods and compositions for producing and screening combinatorial libraries of multimeric proteins. The present invention relies on the use of filamentous fungal heterokaryons that are produced using two or more parent strains into which a population of DNA molecules encoding variants of a multimeric protein have been introduced.

公开(公告)号：EP1303595A2

公开(公告)日：2003-04-23

申请号：EP01984336.6

申请日：2001-07-25

申请人： Cognis Corporation

发明人： CRAFT, David, L. ,  MADDURI, Krishna, M. ,  LOPER, John, C.

IPC分类号： C12N15/04 ,  C07K14/40 ,  C12N15/80 ,  C12N1/15 ,  C12P7/44

CPC分类号： C07K14/40

摘要： A gene has been isolated which encodes cytochrome b5 (CYTb5) protein of the omega-hydroxylase complex of C. tropicalids 20336. Vectors including this gene, and transformed host cells are provided. Methods of increasing the production of a CYTb5 protein are also provided which involve transforming a host cell with a gene encoding this protein and culturing the cells. Methods of increasing the production of a dicarboxylic acid are also provided which involve increasing in the host cell the number of genes encoding this protein.

公开(公告)号：EP0743986B1

公开(公告)日：2002-01-16

申请号：EP95911598.1

申请日：1995-02-02

申请人： UNIVERSITY OF HAWAII

发明人： STUART, W. Dorsey

IPC分类号： C12N15/04 ,  C12N15/16

CPC分类号： C40B40/02 ,  C07K14/59 ,  C12N15/04 ,  C12N15/1037

摘要： The invention relates to a heterokaryotic filamentous fungus host capable of producing a heterologous heterodimer comprising at least two subunits. The heterokaryon contains a first and second nucleus; each nucleus contains an expression system for one subunit of the heterodimer. The heterokaryon is prepared by culturing together a first fungus host strain and a second fungus host strain that is homozygous with the first fungus host strain with respect to all heterokaryon compatibility alleles, wherein the first and second fungus host strains are cultured together under conditions wherein neither the first nor the second fungus strain can survive unless the heterokaryotic host is formed.

公开(公告)号：EP0711305B1

公开(公告)日：2001-11-21

申请号：EP95906203.5

申请日：1994-07-20

申请人： UNIVERSITY OF CALIFORNIA, LOS ANGELES

发明人： LEHRER, Robert L. ,  HARWIG, Sylvia S.L. ,  KOKRYAKOV, Vladimir N.

IPC分类号： C07K7/00 ,  C07K7/08 ,  C07K7/64 ,  C12N15/03 ,  C12N15/04 ,  C12N15/05 ,  C12N15/06 ,  C12N15/12

CPC分类号： C07K7/08 ,  A01N63/02 ,  A61K38/00 ,  C07K16/18

公开(公告)号：EP1054987A1

公开(公告)日：2000-11-29

申请号：EP99905050.3

申请日：1999-02-16

申请人： ZENECA LIMITED

发明人： OSBORN, Rupert William,eneca Agrochemicals ,  WINDASS, John David,Zeneca Agrochemicals ,  ACLAND, David Paul,Zeneca Agrochemicals ,  BLAKE, Andrew Nicholas,Zeneca Agrochemicals ,  ROBINSON, Michael Peter,Zeneca Agrochemicals ,  LEE, Michael David,Zeneca Agrochemicals

IPC分类号： C12N15/82 ,  C12N15/04 ,  C07K14/37 ,  C12N5/10 ,  A01H5/00

CPC分类号： C12N15/8286 ,  C07K14/37 ,  Y02A40/162

摘要： Insecticidal peptides comprising the amino acid sequence CX X X RECGSCX CNX WKGKCEX (SEQ ID NO 1), where X , X , X , X , X and X are any amino acid; or a fragment thereof, or a homologue or variant or derivative of any of these are described and claimed together with nucleotide sequences encoding these peptides. They may be applied as insecticidal compounds in the form of compositions, or expressed in host cells in particular plant cells. Transgenic plants which express peptides of the invention are described.