公开(公告)号：EP1371730B1

公开(公告)日：2009-07-08

申请号：EP02703488.3

申请日：2002-02-22

申请人： CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB)

发明人： IGLESIAS PEREZ, Enrique ,  VAZQUEZ BLOMQUIST, Dania, M. ,  DUARTE CANO, Carlos, A.

IPC分类号： C12N15/48 ,  C12N15/62 ,  C07K14/065 ,  C07K14/155

CPC分类号： C07K14/005 ,  A61K2039/525 ,  C12N15/86 ,  C12N2740/16122 ,  C12N2740/16322

公开(公告)号：EP0905140B1

公开(公告)日：2008-09-10

申请号：EP97914561.2

申请日：1997-03-28

申请人： Zeon Corporation

发明人： SAITO, Shuji, Nippon Zeon Co., Ltd. ,  TSUZAKI, Yoshinari, Nippon Zeon Co., Ltd. ,  YANAGIDA, Noboru, Nippon Zeon Co., Ltd.

IPC分类号： C07K14/30 ,  C07K14/055 ,  C07K14/035 ,  C07K14/065 ,  C12N15/31 ,  C12N15/38 ,  C12N15/62 ,  C12N15/863 ,  C12N7/01 ,  A61K39/255

CPC分类号： C12N15/86 ,  A61K39/00 ,  C07K14/005 ,  C07K14/30 ,  C07K2319/00 ,  C07K2319/02 ,  C12N2710/16322 ,  C12N2710/16622 ,  C12N2710/24043

公开(公告)号：EP1158850B1

公开(公告)日：2008-07-16

申请号：EP00908824.6

申请日：2000-03-10

申请人： COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION

发明人： DALL, David, James

IPC分类号： A01N25/00 ,  A01N63/02 ,  C12N15/82 ,  C07K14/065

CPC分类号： C07K14/005 ,  A01N25/006 ,  A01N63/02 ,  C12N15/8286 ,  C12N2710/24022 ,  Y02A40/162

摘要： Plants are disclosed which are capable of expressing, in a tissue or tissues susceptible to damage by feeding insects, an exogenous protein(s) such as fusolin or a fusolin-like protein, to reduce damage to the plant by inhibiting feeding, growth and/or development of insects. Feed baits comprising spindle bodies, spindle-like bodies or constituent protein(s) thereof which inhibit feeding, growth and/or development of insects are also disclosed.

公开(公告)号：EP1834960A3

公开(公告)日：2007-10-03

申请号：EP07011281.8

申请日：2001-12-04

申请人： Viron Therapeutics, Inc.

发明人： The designation of the inventor has not yet been filed

IPC分类号： C07K14/065 ,  C12N15/39 ,  A61P37/00 ,  A61K48/00 ,  A61K38/16 ,  G01N33/68

CPC分类号： C07K14/005 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C12N2710/24022

摘要： This invention features a therapeutic composition for the treatment of an inflammatory or immune-mediated disease condition, the therapeutic composition comprising an isolated Yatapoxvirus cytokine inhibitor protein formulated in a pharmaceutically acceptable vehicle, a method of modulating cytokine function in a cell in vitro, said method comprising contacting said cell with an isolated Yatapoxvirus cytokine inhibitor protein and the use of an isolated Yatapoxvirus cytokine inhibitor protein for the manufacture of a medicament for the treatment of an inflammatory or immune-mediated disease condition.

公开(公告)号：EP1791859A1

公开(公告)日：2007-06-06

申请号：EP05783052.3

申请日：2005-09-02

申请人： Alcami Pertejo, Antonio

发明人： ALEJO HERBERG, Ali ,  RUIZ-ARGUELLO, Maria Begoña ,  HO, Yin ,  SARAIVA, Margarida ,  SMITH, Vicent, P.

IPC分类号： C07K14/065 ,  G01N33/50 ,  C12N15/62 ,  A61K38/16 ,  C12N15/39

CPC分类号： C07K14/70578 ,  C07K14/005 ,  C07K2319/32 ,  C12N2710/14143 ,  C12N2710/24122 ,  G01N2333/70578

摘要： Chemokine binding activity of viral TNF receptors and related proteins. The invention relates to a C-terminal domain (CTD) of viral tumour necrosis factor receptors (vTNFRs) CrmB or CrmD or CTD homologues (CTD1, CTD2 and CTD3) from poxvirus and their functional homologues, including derivatives, and fragments, for use in binding chemokines and their analogues and/or to enhance the immunomodulatory properties of TNFRs or in bloking binding of chemokines to their corresponding cell surface receptors and/or to modulate chemokine biological activity.

公开(公告)号：EP0886679B1

公开(公告)日：2007-06-06

申请号：EP97904453.4

申请日：1997-02-17

申请人： Bayer HealthCare AG

发明人： SCHMEER, Norbert ,  STRUBE, Walter ,  BÜTTNER, Mathias ,  RZIHA, Hans-Joachim

IPC分类号： C12N15/86 ,  C12N15/39 ,  C07K14/065 ,  C12N7/01 ,  A61K39/275 ,  C12N15/11

CPC分类号： C12N15/86 ,  A61K39/00 ,  C07K14/005 ,  C12N2710/24222 ,  C12N2710/24243

摘要： The invention concerns recombinantly produced parapoxviruses which carry in their genome deletions or insertions in the form of foreign hereditary information and contain other hereditary information. The invention also concerns the production of such constructs and their use in vaccines.

公开(公告)号：EP1414848A4

公开(公告)日：2006-07-19

申请号：EP02752202

申请日：2002-07-09

申请人： BOGOCH SAMUEL ,  BOGOCH ELENORE S

发明人： BOGOCH SAMUEL DR ,  BOGOCH ELENORE S

IPC分类号： A61K39/00 ,  C07K14/005 ,  C07K14/065 ,  C07K14/11 ,  C07K14/195 ,  C07K14/205 ,  C07K14/21 ,  C07K14/22 ,  C07K14/24 ,  C07K14/245 ,  C07K14/255 ,  C07K14/26 ,  C07K14/27 ,  C07K14/28 ,  C07K14/285 ,  C07K14/30 ,  C07K14/305 ,  C07K14/31 ,  C07K14/315 ,  C07K14/32 ,  C07K14/33 ,  C07K14/335 ,  C07K14/34 ,  C07K14/345 ,  C07K14/35 ,  C07K14/355 ,  C07K14/36 ,  C07K14/37 ,  C07K14/38 ,  C07K14/385 ,  C07K14/39 ,  C07K14/395 ,  C07K14/40 ,  C07K14/415 ,  C07K14/44 ,  C07K14/445 ,  C07K14/47 ,  C12N9/00 ,  C12N15/82

CPC分类号： C07K14/195 ,  A61K39/00 ,  A61K2039/505 ,  A61K2039/53 ,  C07K14/205 ,  C07K14/245 ,  C07K14/30 ,  C07K14/31 ,  C07K14/32 ,  C07K14/35 ,  C07K14/37 ,  C07K14/415 ,  C07K14/445 ,  C12N9/93 ,  C12N15/8261 ,  Y02A40/146

摘要： The present invention provides a new class of peptides related to rapid replication and their use in diagnosing, preventing and treating disease.

公开(公告)号：EP1575614A1

公开(公告)日：2005-09-21

申请号：EP02808241.0

申请日：2002-12-17

申请人： Bayer HealthCare AG

发明人： WEBER, Olaf,c/o Bayer Corp. ,  FRIEDERICHS, Sonja Maria ,  SIEGLING, Angela ,  SCHLAPP, Tobias ,  MERCER, Andrew Allan ,  FLEMING, Stephen Bruce ,  VOLK, Hans-Dieter

IPC分类号： A61K39/275 ,  A61K48/00 ,  C07K14/065 ,  C12N5/10 ,  C12N15/39 ,  C12N15/863

CPC分类号： C12N15/86 ,  A61K38/00 ,  A61K2039/525 ,  C07K14/005 ,  C07K2319/00 ,  C12N7/00 ,  C12N2710/24143 ,  C12N2710/24221 ,  C12N2710/24222 ,  C12N2710/24233 ,  C12N2710/24243

摘要： The invention relates to polynucleotides coding for the PPVO viral genome, to fragments of the polynucleotides coding for the PPVO genome and to polynucleotides coding for individual open reading frames (ORFs) of the PPVO viral genome. The invention also relates to recombinant proteins expressed from the above mentioned polynucleotides and to fragments of said recombinant proteins, and to the use of said recombinant proteins or fragments for the preparation of pharmaceutical compositions.

公开(公告)号：EP1331943A4

公开(公告)日：2005-01-26

申请号：EP01979821

申请日：2001-10-11

申请人： VIRON THERAPEUTICS INC

发明人： MCFADDEN GRANT ,  ESSANI KARIM

IPC分类号： A01K67/027 ,  A61K38/00 ,  A61K39/275 ,  A61P1/04 ,  A61P1/16 ,  A61P3/10 ,  A61P5/16 ,  A61P7/00 ,  A61P7/06 ,  A61P7/08 ,  A61P9/10 ,  A61P11/00 ,  A61P11/02 ,  A61P11/06 ,  A61P13/12 ,  A61P15/06 ,  A61P17/00 ,  A61P17/02 ,  A61P17/06 ,  A61P19/00 ,  A61P21/02 ,  A61P21/04 ,  A61P25/00 ,  A61P25/28 ,  A61P29/00 ,  A61P31/12 ,  A61P31/18 ,  A61P35/02 ,  A61P37/02 ,  A61P37/04 ,  A61P37/06 ,  A61P37/08 ,  A61P43/00 ,  C07K14/065 ,  C07K16/08 ,  C12N5/10 ,  C12N15/09 ,  C12Q1/02 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/50 ,  G01N33/53 ,  G01N33/566 ,  G01N33/569 ,  C07K14/07

CPC分类号： C07K14/005 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  C12N2710/24022

公开(公告)号：EP0835133A4

公开(公告)日：2003-01-02

申请号：EP96922173

申请日：1996-06-03

申请人： VIROGENETICS CORP

发明人： PAOLETTI ENZO ,  MAKI JOANNE

IPC分类号： C12N15/09 ,  A61K39/00 ,  A61K39/175 ,  A61K39/205 ,  A61K39/235 ,  A61K39/275 ,  A61K39/295 ,  A61K39/35 ,  A61P31/12 ,  A61P37/04 ,  C07K14/015 ,  C07K14/02 ,  C07K14/03 ,  C07K14/035 ,  C07K14/045 ,  C07K14/05 ,  C07K14/06 ,  C07K14/065 ,  C07K14/07 ,  C07K14/11 ,  C07K14/12 ,  C07K14/125 ,  C07K14/145 ,  C07K14/15 ,  C07K14/155 ,  C07K14/16 ,  C07K14/175 ,  C07K14/18 ,  C07K14/33 ,  C12N7/00 ,  C12N7/01 ,  C12N15/863 ,  A61K39/285

CPC分类号： C07K14/005 ,  A61K39/00 ,  A61K2039/5254 ,  A61K2039/70 ,  C07K14/33 ,  C07K2319/00 ,  C12N15/86 ,  C12N2710/16222 ,  C12N2710/16622 ,  C12N2710/16722 ,  C12N2710/24022 ,  C12N2710/24043 ,  C12N2710/24122 ,  C12N2710/24143 ,  C12N2730/10122 ,  C12N2740/13022 ,  C12N2740/15022 ,  C12N2740/16122 ,  C12N2740/16222 ,  C12N2750/14322 ,  C12N2760/12022 ,  C12N2760/16122 ,  C12N2760/18122 ,  C12N2760/18722 ,  C12N2760/20022 ,  C12N2760/20122 ,  C12N2770/24022 ,  C12N2770/24122 ,  Y10S530/826

摘要： Attenuated recombinant viruses containing DNA encoding a rabies virus antigen in a 'cocktail' or combination or multivalent compositions as well as methods for making and using the compositions, expression products therefrom, and antibodies generated, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The compositions and products therefrom and antibodies generated have several preventive, therapeutic and diagnostic uses.