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    GENES ENCODING PROTEINS HAVING ACTIVITY OF TRANSFERRING SUGAR ONTO AURONE
    65.
    发明公开
    GENES ENCODING PROTEINS HAVING ACTIVITY OF TRANSFERRING SUGAR ONTO AURONE 审中-公开
    GENE，DIEFÜRPROTEINE KODIEREN，DIE EINE ZUCKER-ÜBERTRAGUNGSAKTIVITÄTAUF AURON BESITZEN

    公开(公告)号：EP1072684A1

    公开(公告)日：2001-01-31

    申请号：EP00903988.4

    申请日：2000-02-16

    申请人： SUNTORY LIMITED

    发明人： SAKAKIBARA, Keiko ,  FUKUI, Yuko ,  TANAKA, Yoshikazu ,  KUSUMI, Takaaki ,  YOSHIKAWA, Takafumi

    IPC分类号： C12N15/54 ,  C12N1/21 ,  C12N9/10 ,  A01H5/00 ,  C12P19/18

    CPC分类号： C12N15/825 ,  C12N9/1048 ,  C12N9/1051 ,  C12N15/8243 ,  C12P19/60

    摘要： There is provided a gene encoding a protein derived from, for example, snapdragons and petunias, said protein having an amino acid sequence as set forth in SEQ ID NO: 2, 8, and 10, and having an activity of transferring a glycosyl group to aurones, and a method of producing said protein using said gene. By introducing this gene into plants that do not have said gene, a yellow pigment aurone can be stabilized and plants having yellow flowers can be obtained.

    摘要翻译： 提供了编码来自例如快速聚糖和矮牵牛的蛋白质的基因，所述蛋白质具有如SEQ ID NO：2,8和10所示的氨基酸序列，并且具有将糖基转移到 噢ones，以及使用该基因产生所述蛋白质的方法。 通过将该基因导入到不具有该基因的植物中，可以稳定黄色颜料噢one one can，可以得到具有黄花的植物。

    TRANSGENIC ANIMAL SHOWING VASCULAR TISSUE-SPECIFIC EXPRESSION OF ANGIOTENSIN II2 RECEPTOR
    66.
    发明公开
    TRANSGENIC ANIMAL SHOWING VASCULAR TISSUE-SPECIFIC EXPRESSION OF ANGIOTENSIN II2 RECEPTOR 审中-公开
    转基因食品GEFÄSS-SPEZIFISCHER EXPRESSION DES ANGIOTENSIN-II2-REZEPTORS。

    公开(公告)号：EP1070454A1

    公开(公告)日：2001-01-24

    申请号：EP00902092.6

    申请日：2000-02-04

    申请人： SUNTORY LIMITED

    发明人： KURIHARA, Tatsuya ,  MATSUBARA, Hiroaki

    IPC分类号： A01K67/027 ,  C12N15/12 ,  C12N15/11 ,  C12N5/10 ,  C12N5/06 ,  G01N33/50 ,  G01N33/15

    CPC分类号： A01K67/0275 ,  A01K2217/05 ,  A01K2227/105 ,  A01K2267/03 ,  A01K2267/0375 ,  C07K14/705 ,  C12N15/8509 ,  C12N2503/02 ,  C12N2517/02 ,  C12N2830/008

    摘要： A transgenic animal and its progeny that vascular tissue-specifically express angiotensin II type 2 receptor; a method for producing said transgenic animal and its progeny; a recombinant gene for producing a transgenic animal, containing a promoter region derived from a protein gene expressed in vascular tissue and an angiotensin II type 2 receptor gene; a vascular tissue fragment or vascular cell derived from a transgenic animal that vascular tissue-specifically expresses angiotensin II type 2 receptor; a method for in vivo analyzing vascular physiological action and/or blood pressure-regulating action of angiotensin II type 2 receptor using said transgenic animal; and a method for in vitro analyzing vascular physiological action and/or blood pressure-regulating action of angiotensin II type 2 receptor using said vascular tissue fragment or vascular cell.

    摘要翻译： 转基因动物及其后代血管组织特异性表达血管紧张素II 2型受体; 一种生产所述转基因动物及其后代的方法; 用于产生转基因动物的重组基因，其含有源自血管组织中表达的蛋白质基因的启动子区域和血管紧张素II2型受体基因; 来自转基因动物的血管组织片段或血管细胞，血管组织特异性表达血管紧张素II 2型受体; 使用所述转基因动物体内分析血管生理作用和/或血管紧张素II 2型受体的血压调节作用的方法; 以及使用所述血管组织片段或血管细胞体外分析血管生理作用和/或血管紧张素II 2型受体的血压调节作用的方法。

    Beta-hydroxyaspartic acid derivatives
    67.
    发明公开
    Beta-hydroxyaspartic acid derivatives 失效

    公开(公告)号：EP0948962A3

    公开(公告)日：2000-09-20

    申请号：EP99113601.1

    申请日：1997-10-24

    申请人： SUNTORY LIMITED

    发明人： Shimamoto, Keiko ,  Yasuda, Yoshimi ,  Sakaitani, Masahiro ,  Lebrun, Bruno

    IPC分类号： C07C229/24 ,  A61K31/195 ,  A23L1/305

    CPC分类号： C07C229/24 ,  A23L33/175

    摘要： The present invention provides blockers for glutamate transporters. During a series of syntheses searching for glutamate uptake inhibition in Xenopus oocytes injected with bovine glutamate transporter genes (BGLAST), we obtained β-hydroxyaspartic acid derivatives of the following chemical formula (1): wherein R represents an aromatic acyl group which may be substituted on the ring, a straight or branched lower aliphatic acyl group, an aryl group which may be substituted on the ring, an aralkyl group which may be substituted on the ring, or a straight or branched lower alkyl group; and salts thereof. These compounds are blockers of glutamate transporters, which are useful for the understanding of the function of glutamate transporters and show promise for the treatment of various neurodegenerative diseases.

    VEHICLE ALLOCATING SYSTEM AND VEHICLE ALLOCATING DEVICE
    68.
    发明公开
    VEHICLE ALLOCATING SYSTEM AND VEHICLE ALLOCATING DEVICE 有权
    VERFAHREN UNDGERÄTZUR ZUORDNUNG VON FAHRZEUGEN

    公开(公告)号：EP1003140A1

    公开(公告)日：2000-05-24

    申请号：EP99919603.3

    申请日：1999-05-14

    申请人： SUNTORY LIMITED

    发明人： NAKAGAWA, Kazuya ,  AIDA, Tsuyoshi ,  KUMAMOTO, Kazuhiro ,  KONISHI, Nobuyuki ,  NISHIDA, Hajime

    IPC分类号： G08G1/00 ,  G08G1/13 ,  G06F17/60

    CPC分类号： G06Q10/047 ,  G06Q10/0631 ,  G06Q10/08 ,  G08G1/202

    摘要： A transportation arrangement center for drawing up an operations plan is arranged between shippers and both physical distribution centers and transportation bases. The transportation arrangement center is provided with a master data managing unit for managing cargo item data, physical distribution center data, and vehicle and garage data concerning vehicles managed by the transportation bases and their garages and with a route making unit for making routes, taking in consideration also priority vehicles, based on the data of the cargoes, physical distribution centers, vehicles, and garages. The route making unit sets the efficient routes satisfying the transportation orders from the shippers and the restraint conditions on operation, minimizing the number of vehicles dispatched, and selecting the optimum transportation bases. This gives a transportation arrangement system capable of improving the physical distribution efficiency while keeping down the total number of vehicles dispatched.

    摘要翻译： 在托运人和物流中心和运输基地之间安排了一个拟订运营计划的运输安排中心。 运输安排中心设有一个主数据管理单元，用于管理运输基地及其车库管理的货物数据，物流配送中心数据，以及车辆和车库数据，以及用于制造路线的路线制造单元 根据货物，物流配送中心，车辆和车库的数据，考虑重点车辆。 航线制造单位设定满足托运人运输订单的有效路线和运行约束条件，最大限度地减少发送车辆数量，选择最佳运输基础。 这提供了一种能够提高物理分配效率同时降低发出的车辆总数的运输安排系统。

    POMPILID WASP-DERIVED NEUROPEPTIDES
    69.
    发明公开
    POMPILID WASP-DERIVED NEUROPEPTIDES 有权
    WESPE POMPILID神经病学

    公开(公告)号：EP0998494A1

    公开(公告)日：2000-05-10

    申请号：EP98938946.5

    申请日：1998-08-24

    申请人： SUNTORY LIMITED

    发明人： ITAGAKI, Yasuhiro ,  KONNO, Katsuhiro ,  KAWAI, Nobufumi ,  TAKAYAMA, Hiroaki

    IPC分类号： C07K14/435 ,  A61K38/16

    CPC分类号： C07K14/43568 ,  A61K38/00

    摘要： The present invention provides a peptide represented by the amino acid sequence formula (A): H-X1-X2-X3-X4-Gly-X6-X7-Asp-Gln-R wherein: each of X1 and X3 independently represents Arg or Lys, each of X2, X4 and X6 independently represents Ile or Leu, and X7 represents Phe, Tyr or Trp; and R represents -NH2, -Leu-NH2, -Leu-Ser-NH2, -Leu-Ser-Lys-NH2, -Leu-Ser-Arg-NH2, Leu-Ser-Lys-Leu-NH2, or -Leu-Ser-Arg-Leu-NH2; and a salt thereof. In the above, Gly stands for a glycine residue, Asp stands for an aspartic acid residue, Gln stands for a glutamine residue, Arg stands for an arginine residue, Lys stands for a lysine residue, Ile stands for an isoleucine residue, Leu stands for a leucine residue, Phe stands for a phenylalamine residue, Tyr stands for a tyrosine residue, Trp stands for a tryptophan residue, and Ser stands for a serine residue. The peptide acts on glutamate receptors and is expected to be useful in the treatment of cerebral nerve diseases associated with glutamic acid.