公开(公告)号：EP2693970A4

公开(公告)日：2014-12-17

申请号：EP12865090

申请日：2012-04-09

Applicant: COVIDIEN LP

Inventor： BRANNAN JOSEPH D ,  ARTS GENE H ,  DECARLO ARNOLD V ,  LADTKOW CASEY M ,  REID WILLIAM O JR

IPC: A61B18/18 ,  A61B18/00 ,  A61M25/00 ,  A61M25/01 ,  A61M25/10 ,  A61N5/02

CPC classification number: A61B18/1815 ,  A61B17/00234 ,  A61B18/1492 ,  A61B18/18 ,  A61B90/10 ,  A61B2017/00323 ,  A61B2018/00023 ,  A61B2018/00077 ,  A61B2018/00172 ,  A61B2018/0022 ,  A61B2018/00226 ,  A61B2018/00232 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00345 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/1846 ,  A61B2018/1861 ,  A61B2018/1884 ,  A61B2018/1892 ,  A61N5/022

公开(公告)号：EP2457615B1

公开(公告)日：2014-12-17

申请号：EP11192514.5

申请日：2005-10-05

Applicant: Medtronic Ardian Luxembourg S.à.r.l.

Inventor： Deem, Mark ,  Gifford, Hanson ,  Demarais, Denise ,  Sutton, Douglas ,  Thai, Erik ,  Gelfand, Mark ,  Levin, Howard R.

IPC: A61N1/08 ,  A61N1/05 ,  A61N1/32 ,  A61B18/14

CPC classification number: A61N1/36007 ,  A61B8/0891 ,  A61B8/12 ,  A61B18/1206 ,  A61B18/1233 ,  A61B18/1492 ,  A61B18/18 ,  A61B2018/00071 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00642 ,  A61B2018/00904 ,  A61B2018/126 ,  A61B2018/1467 ,  A61M5/14 ,  A61M25/0023 ,  A61N1/0412 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/18 ,  A61N1/205 ,  A61N1/326 ,  A61N1/327 ,  A61N1/36017 ,  A61N1/36057 ,  A61N1/3606 ,  A61N1/36103 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36139 ,  A61N5/00 ,  A61N7/00 ,  A61N2007/0021 ,  A61N2007/003

Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.

公开(公告)号：EP2809399A1

公开(公告)日：2014-12-10

申请号：EP13744162.2

申请日：2013-01-30

Applicant: Vytronus, Inc.

Inventor： PEDERSON, Michael, J. ,  PHILLIPS, Patrick, J. ,  MADDEN, John, P. ,  HORZEWSKI, Michael, J.

IPC: A61N7/02

CPC classification number: A61N7/02 ,  A61B17/2202 ,  A61B17/3478 ,  A61B2017/22021 ,  A61B2018/00011 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61N7/022 ,  A61N2007/0043 ,  A61N2007/0052 ,  A61N2007/0069 ,  A61N2007/0078 ,  A61N2007/0091 ,  A61N2007/0095

Abstract: Apparatus and methods for creating tissue necrosis include an energy delivery apparatus that can be positioned adjacent a target treatment site such as a vessel without direct contact with the treatment site tissue. Collimated energy is then directed to the vessel to create necrotic regions in the tissue. Exemplary use in renal vessels creates necrotic regions in adjacent nerves which can alleviate hypertension in a patient.

公开(公告)号：EP2804554A1

公开(公告)日：2014-11-26

申请号：EP12779222.4

申请日：2012-09-28

Applicant: Boston Scientific Scimed, Inc.

Inventor： SHIREMAN, Brice L. ,  REYNOLDS, Brian R. ,  ROUTH, Katherine ,  HANSON, Brian J.

IPC: A61B18/14 ,  A61M25/00

CPC classification number: A61B18/1492 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61M25/0013 ,  A61M25/0051 ,  A61M25/0054 ,  A61M25/0147 ,  A61M2025/0046

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a renal nerve modulation device. The renal nerve modulation device may include an elongate catheter shaft having a distal portion. An ablation member may be coupled to the distal portion. The catheter shaft may have a slotted portion having a plurality of slots formed therein. At least some of the slots formed in the slotted portion may define a plurality of beams in the slotted portion that extend along the slotted portion and that are aligned in a wave pattern.

公开(公告)号：EP2790768A1

公开(公告)日：2014-10-22

申请号：EP12857827.5

申请日：2012-12-14

Applicant: The Board of Trustees of the Leland Stanford Junior University

Inventor： GNANASHANMUGAM, Swaminadhan ,  KOEHLER, Jeremy Christopher ,  SUH, Insoo ,  COE, Jonathan A.

IPC: A61M25/10 ,  A61M25/088 ,  A61M25/09

CPC classification number: A61M25/0043 ,  A61B17/00 ,  A61B18/02 ,  A61B18/04 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/1815 ,  A61B2018/0022 ,  A61B2018/00345 ,  A61B2018/00357 ,  A61B2018/00375 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/0212 ,  A61B2018/143 ,  A61B2018/1432 ,  A61M25/00 ,  A61M25/10 ,  A61M25/1002 ,  A61M29/00 ,  A61M29/02 ,  A61M2025/006 ,  A61N2/02 ,  A61N2/06 ,  A61N5/1002 ,  A61N7/022 ,  A61N2007/003

Abstract: A method is described for decreasing activity of at least one sympathetic nerve, nerve fiber or neuron innervating at least one blood vessel in the pulmonary vasculature of a patient to ameliorate pulmonary hypertension. In one embodiment, the method may involve advancing an intravascular treatment device to a target location in a target blood vessel within the pulmonary vasculature of the patient and using the treatment device to decrease activity of at least one sympathetic nerve, nerve fiber or neuron innervating the target blood vessel at or near the target location to ameliorate pulmonary hypertension.

公开(公告)号：EP2709517A4

公开(公告)日：2014-10-22

申请号：EP12785788

申请日：2012-05-17

Applicant: ST JUDE MEDICAL

Inventor： NG KOK-HWEE

IPC: A61B5/00

CPC classification number: A61B5/201 ,  A61B5/0215 ,  A61B5/4041 ,  A61B5/6853 ,  A61B18/1492 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00839 ,  A61B2018/1467

公开(公告)号：EP2777729A1

公开(公告)日：2014-09-17

申请号：EP14160297.9

申请日：2014-03-17

Applicant: Custom Medical Applications

Inventor： Racz, N. Sandor

IPC: A61M5/00 ,  A61B17/34 ,  A61M5/32 ,  A61M25/00 ,  A61B19/00

CPC classification number: A61B17/3415 ,  A61B17/3401 ,  A61B17/3496 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/1425 ,  A61M5/3291 ,  A61M19/00 ,  A61M25/007 ,  A61M2025/0089 ,  A61N1/05 ,  A61N1/3606

Abstract: A novel neural injection system and related methods are herein disclosed. Various embodiments of an embodiment of a neural injection system of the present invention provide for at least one benefit of enhanced injection characteristics, increased operational efficiency, reduced cost per unit, reduced incidence of injury through intraneural/intravascular injection, reduced incidence of injury through pricking/piercing, and/or the like.

Abstract translation: 本文公开了一种新颖的神经注射系统和相关方法。 本发明的神经注射系统的一个实施方案的各种实施方案提供了增强的注射特征，增加的操作效率，降低的单位成本，通过神经内/血管内注射减少的损伤发生率，通过刺痛引起的损伤发生率的减少 /穿孔等等。

公开(公告)号：EP2775948A1

公开(公告)日：2014-09-17

申请号：EP12788052.4

申请日：2012-11-07

Applicant: Boston Scientific Scimed, Inc.

Inventor： WILLARD, Martin R.

IPC: A61B18/14 ,  A61B18/00

CPC classification number: A61B18/1492 ,  A61B18/082 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00375 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61N7/022 ,  A61N2007/003 ,  F04C2270/041

Abstract: A catheter including an elongated shaft having a distal end and a proximal end, where the catheter includes a thermal element at the distal end thereof. The thermal element may be used in an ablation procedure or other procedure to heat a tissue adjacent a vessel. In some instances, the thermal element may be positioned in a first vessel and may operate to heat tissue adjacent a second vessel or adjacent an ostium between the first vessel and the second vessel. Further, the catheter may include an expandable portion on which the thermal element may be connected or positioned. The expandable portion(s) may comprise a basket or cage, a balloon, a memory shape and formable portion, and/or other mechanical expanders.

Abstract translation: 包括具有远端和近端的细长轴的导管，其中导管在其远端包括热元件。 热元件可用于消融程序或其他程序以加热血管附近的组织。 在一些情况下，热元件可以定位在第一容器中，并且可以操作以加热邻近第二容器或邻近第一容器和第二容器之间的孔口的组织。 此外，导管可以包括可膨胀部分，热元件可以连接或定位在膨胀部分上。 可膨胀部分可以包括篮子或笼子，球囊，记忆形状和可成形部分，和/或其他机械膨胀器。

公开(公告)号：EP2765942A1

公开(公告)日：2014-08-20

申请号：EP12778581.4

申请日：2012-10-10

Applicant: Boston Scientific Scimed, Inc.

Inventor： JENSON, Mark L.

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B5/6858 ,  A61B2017/00526 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  Y10T29/49204

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may be a renal nerve modulation catheter. The catheter may include an elongate catheter shaft. The catheter shaft may have a plurality of cuts formed therein define a plurality of electrode assemblies. The electrode assemblies may each include a main strut, one or more branched spacer struts extending from the main strut, and an electrode extending from the main strut and positioned radially inward from the spacer struts.

公开(公告)号：EP2747691A1

公开(公告)日：2014-07-02

申请号：EP12828954.3

申请日：2012-08-24

Applicant: Symap Holding Limited

Inventor： WANG, Jie

IPC: A61B18/14 ,  A61B5/00

CPC classification number: A61B18/1492 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/024 ,  A61B5/04001 ,  A61B5/0538 ,  A61B5/201 ,  A61B5/4833 ,  A61B5/4836 ,  A61B5/4893 ,  A61B5/6852 ,  A61B5/6853 ,  A61B18/18 ,  A61B18/24 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00708 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61N1/36117 ,  A61N7/02 ,  A61N2007/003 ,  G06F19/00 ,  G16Z99/00

Abstract: System and method for locating and identifying nerves innervating the wall of arteries such as the renal artery are disclosed. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The method includes at least the steps to evaluate a change in physiological parameters after energy is delivered to an arterial wall; and to determine the type of nerve that the energy was directed to (none, sympathetic or parasympathetic) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using this method. Also provided are catheters for performing the mapping and ablating functions.

Abstract translation: 系统和方法，用于定位和识别神经支配动脉的壁：诸如肾动脉的游离缺失盘。 本发明鉴定的血管壁并都与支配神经上的区域; 提供无论能量的剂量递送的精确地设定到目标神经指示; 并提供传递到神经能量的效果立竿见影后的程序评估。 该方法包括至少以下步骤来评估能量的剂量的动脉壁被输送到后在生理参数的变化; 并确定矿井神经类型做了哪些针对基于评估结果（无，交感副交感神经或）的能量。 该系统至少包括用于输送一定剂量的能量到动脉壁的装置; 传感器用于检测来自受试者的生理信号; 和指标来显示使用所述方法获得的结果。