公开(公告)号：EP2869763A4

公开(公告)日：2016-03-09

申请号：EP13813805

申请日：2013-07-02

申请人： EDWARDS LIFESCIENCES CORP

发明人： DOBBLES JOHN MICHAEL ,  KEIDAR YARON ,  DEPALMA AMANDA L

IPC分类号： A61B5/145 ,  A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/02 ,  A61B5/14542 ,  A61B5/1495 ,  A61B5/4064 ,  A61B5/4839 ,  A61B5/6876 ,  A61B5/7278 ,  A61B5/7435 ,  A61M5/1723 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/70 ,  A61M2205/702 ,  A61M2230/005 ,  A61M2230/201 ,  A61M2230/202 ,  A61M2230/205

摘要： Apparatus and methods for monitoring and indexing glucose consumption are disclosed. Embodiments of the present invention provide for accurate measurement of small differences in blood glucose values at various points in the body. These accurate measurements can be used to monitor glucose uptake in specific organs of the body such as the brain or heart. The apparatus includes an upstream intravascular glucose sensor and a downstream intravascular glucose sensor. In some embodiments, substantially simultaneous fluid communication of a calibration fluid to both glucose sensors reduces bias between the sensors. A processor is used to calculate and optionally display blood glucose consumption. Oxygen consumption can also be determined and used to determine and display an index value that is indicative of any mismatch between the two. In some embodiments, insulin and/or glucose infusion can be controlled by the system.

公开(公告)号：EP2259057B1

公开(公告)日：2016-01-27

申请号：EP10178251.4

申请日：2005-05-20

申请人： Medtronic MiniMed, Inc.

发明人： Saidara, Frank ,  Mastrototaro, John J. ,  Tolle, Charles Vallet ,  Mueller, John C. Jr. ,  Sanders, Jeff B. ,  Nielsen, Edward S.

IPC分类号： G01N33/487 ,  A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/0002 ,  A61B5/14542 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/746 ,  A61B2560/0252 ,  A61B2560/045 ,  G01N33/48792 ,  G06F19/00

摘要： A device, comprising: a sensor input capable of receiving at least one signal from a sensor, the signal being based on a plurality of sensed physiological characteristic values of a user of the device; and a processor coupled to the sensor input for operating a plurality of alarms based on the received signal from the sensor; wherein the processor is capable of activating each of the plurality of alarms according to a different sensed physiological characteristic value of the plurality of sensed physiological characteristic values.

公开(公告)号：EP2967485A1

公开(公告)日：2016-01-20

申请号：EP14763035.4

申请日：2014-03-14

申请人： Seno Medical Instruments, Inc.

发明人： MILLER, Thomas ,  SCHMID, Gregory ,  ACKERMAN, William ,  HERZOG, Donald

IPC分类号： A61B8/00 ,  G01N29/24

CPC分类号： A61B5/726 ,  A61B5/0035 ,  A61B5/0095 ,  A61B5/14542 ,  A61B5/4312 ,  A61B5/7203 ,  A61B5/7425 ,  A61B8/4209 ,  A61B8/4281 ,  A61B2560/0223 ,  A61B2560/0431

摘要： A holder for an optoacoustic probe includes a probe-end enclosing portion formed from material that is substantially opaque to light emanating from an optical window of a probe. The probe-end enclosing portion is sized to enclose the active end of the probe and have a snug fit therewith when the optoacoustic probe is inserted therein, and has minimal or no contact with the optical window and acoustic lens of the probe. The probe holder further includes a cutaway adapted to support the probe's strain relief under the downward force of gravity, thereby supporting the probe at an angle that provides for easy manual grasping and removal. The probe support also blocks an in-holder probe from sliding away from the probe-enclosing end. A cable guide is spaced from the probe support to accept a connecting cable exiting from the proximal end of the probe, and thus reduce pressure on the strain relief and soften the angle of curvature of the connecting cable.

摘要翻译： 一种用于光声探头的保持器包括探针端封闭部分，该探针端封闭部分由对从探针的光学窗口发出的光基本上不透明的材料形成。 当光声探头插入其中时，探头端封闭部分的尺寸被确定为包围探头的有源端并且与其紧密配合，并且与探头的光学窗和声透镜的接触最小或不接触。 探头支架还包括一个切口，该切口适于在向下的重力作用下支撑探头的应变消除装置，从而以一定角度支撑探头，以便于手动抓取和移除。 探头支架还可以阻止持有人探头从探头封闭端滑出。 电缆引导件与探针支撑件间隔开以接收从探针近端离开的连接电缆，并且因此减小应变消除件上的压力并且软化连接电缆的弯曲角度。

公开(公告)号：EP2967484A2

公开(公告)日：2016-01-20

申请号：EP14762521.4

申请日：2014-03-14

申请人： Simon, Adam, J.

发明人： Simon, Adam, J.

IPC分类号： A61B8/00 ,  A61B5/00 ,  A61B5/05 ,  G10L13/00 ,  G10L21/00 ,  G06F15/00

CPC分类号： A61B5/04842 ,  A61B5/024 ,  A61B5/02405 ,  A61B5/0478 ,  A61B5/04845 ,  A61B5/04847 ,  A61B5/0533 ,  A61B5/1118 ,  A61B5/14542 ,  A61B5/16 ,  A61B5/4064 ,  A61B5/4088 ,  A61B5/6803 ,  G06F19/00

摘要： A system and diagnostic signatures which are derived from the data collected in the system captures multiple streams of biological sensor data for assessing brain health and functionality of a user. The system includes a plurality of biological sensors adapted to collect biological sensor data from the user as well as the ability to stimulate the brain in a variety of sensory, cognitive, physical, and chemical challenges. Several of the biological sensors are accommodated in an electronics module mounted on the user's head.

摘要翻译： 从系统中收集的数据导出的系统和诊断签名捕获多个生物传感器数据流，以评估用户的大脑健康和功能。 该系统包括多个生物传感器，适于收集来自用户的生物传感器数据以及在各种感官，认知，物理和化学挑战中刺激大脑的能力。 生物传感器包括主动脑波传感器，除了从加速计测量的平衡和移动，语音和响应的麦克风测量，跟踪图像传感器中选择的一个或多个额外的生物传感器数据流之外，还收集至少一个EEG脑波数据通道 眼动和生物识别，心率，心率变异性和动脉氧的脉搏血氧测量，用于情绪和情绪信息的电流皮肤电导（或皮肤皮肤电导），按键形式的认知数据以及鼠标点击或触摸 认知挑战期间的屏幕事件。 几个生物传感器装在安装在使用者头上的电子模块中。

公开(公告)号：EP2967337A1

公开(公告)日：2016-01-20

申请号：EP14719579.6

申请日：2014-03-14

申请人： Flint Hills Scientific, LLC

发明人： OSORIO, Ivan

IPC分类号： A61B5/00 ,  A61B5/11 ,  A61B5/024 ,  A61B5/0205 ,  A61N1/36 ,  A61B5/053 ,  A61B5/0488

CPC分类号： A61B5/4094 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/021 ,  A61B5/024 ,  A61B5/02405 ,  A61B5/04001 ,  A61B5/0488 ,  A61B5/0533 ,  A61B5/1118 ,  A61B5/1123 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/222 ,  A61B5/4064 ,  A61B5/4266 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/7282 ,  A61N1/36064 ,  G01N2800/2857

摘要： We report method of detecting a pathological body state of a patient, comprising receiving a body signal of the patient; determining a body index from said body signal; determining an activity level of said patient; determining a value range for said body index for said patient, based at least in part on said activity level; comparing said body index to said value range; and detecting a pathological state when said body index is outside said value range. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

公开(公告)号：EP2956066A2

公开(公告)日：2015-12-23

申请号：EP14752036.5

申请日：2014-02-14

申请人： Weber, Paul

发明人： Weber, Paul

IPC分类号： A61B10/02 ,  A61B17/3209 ,  A61B8/08

CPC分类号： A61B10/0045 ,  A61B5/0051 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/01 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1495 ,  A61B5/6847 ,  A61B10/02

摘要： Methods, apparatus and systems for tissue dissection and testing are disclosed herein. A method for tissue dissection and testing may comprise inserting a tissue dissecting wand (TD) through an incision in a patient's body. The TD may comprise a tip having a plurality of protrusions with lysing segments positioned between the protrusions to dissect and/or modify tissue. The TD may also comprise a sensor dock positioned on top of the TD that is configured to allow tissue and/or body fluid contact to a sensor. After separating tissue using the lysing segment(s) to access a target region, the sensor may be activated and moved around within the target region to assess tissues.

公开(公告)号：EP2953541A1

公开(公告)日：2015-12-16

申请号：EP14705879.6

申请日：2014-02-05

申请人： Assistance Publique Hôpitaux De Paris

发明人： VALLEE, Fabrice ,  MATEO, Joaquim ,  PAYEN DE LA GARANDERIE, Didier

IPC分类号： A61B5/1455 ,  A61B5/1477 ,  A61B5/00

CPC分类号： A61B5/026 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/1477 ,  A61B5/1491 ,  A61B5/412 ,  A61B5/4884 ,  A61B5/6816 ,  A61B5/7282

摘要： The present invention relates to a non-invasive method for determining the tissue perfusion state in a patient, by measuring the variations in the skin CO
2 pressure and in the perfusion index of the patient during the conducting of a localized hyperthermia test.

公开(公告)号：EP2950862A1

公开(公告)日：2015-12-09

申请号：EP14700796.7

申请日：2014-01-08

申请人： Koninklijke Philips N.V.

发明人： SANTHANA NAIDU, Navaneetha, Krishnan ,  PADUKONE, Rishab ,  RAMACHANDRAN, Ganesan ,  MAKKAPATI, Vishnu, Vardhan

IPC分类号： A61M16/00

CPC分类号： A61M16/1005 ,  A61B5/11 ,  A61B5/1116 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/4836 ,  A61B5/721 ,  A61B2503/045 ,  A61M16/0003 ,  A61M16/0051 ,  A61M16/0057 ,  A61M16/024 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2202/0208 ,  A61M2205/13 ,  A61M2205/17 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3334 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/42 ,  A61M2205/50 ,  A61M2205/505 ,  A61M2230/205 ,  A61M2230/50 ,  A61M2230/62 ,  A61M2230/63 ,  A61M2240/00 ,  A61M2202/0007 ,  A61M2230/005

摘要： A system and method to control oxygen supply uses determinations whether physiological sensors and/or a subject interface appliance have been displaced in relation to a subject and/or there has been movement of the subject itself. Artifacts that may reduce the accuracy of measurements of physiological parameters, in particular related to a level of arterial oxygen saturation, may be detected through determinations pertaining to sensor displacement, displacement of the subject interface appliance and/or movement of the subject.

公开(公告)号：EP2861191A4

公开(公告)日：2015-12-09

申请号：EP13803958

申请日：2013-06-13

申请人： ZST HOLDINGS INC

发明人： REMMERS JOHN ,  TAM HUGO ,  MACARTNEY TERRY ,  SANTOSHAM PETER ,  TOPOR ZBIGNIEW LUDWIK ,  GROSSE JOSHUA

IPC分类号： A61F5/56 ,  A61B5/00 ,  A61B5/107 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1455 ,  A61C5/14 ,  A61C19/00 ,  A61M21/00

CPC分类号： A61F5/566 ,  A61B5/1072 ,  A61B5/1116 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/4812 ,  A61B5/4818 ,  A61B5/742 ,  A61B2560/0228

公开(公告)号：EP2934300A1

公开(公告)日：2015-10-28

申请号：EP13864092.5

申请日：2013-10-21

申请人： Tufts University

发明人： FANTINI, Sergio

IPC分类号： A61B5/00

CPC分类号： A61B5/7278 ,  A61B5/0075 ,  A61B5/02028 ,  A61B5/0263 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/4064 ,  A61B5/7257

摘要： A method for inferring characteristics of a physiological system includes measuring one or more physiological signals in the physiological system and inferring characteristics of the physiological system from the one or more measured physiological signals using a multiple vascular compartment hemodynamic model, the multiple vascular compartment hemodynamic model defining a relationship between the one or more measured physiological signals and the characteristics of the physiological system. When the one or more measured physiological signals include coherent oscillations at a plurality of frequencies, the method is termed coherent hemodynamics spectroscopy. The multiple vascular compartment hemodynamic model is based on an average time spent by blood in one or more of said vascular compartments and a rate constant of oxygen diffusion.