公开(公告)号：EP3874058A2

公开(公告)日：2021-09-08

申请号：EP19899577.1

申请日：2019-11-01

申请人： President And Fellows Of Harvard College

发明人： LIU, Ninning ,  YIN, Peng ,  SAKA, Sinem K. ,  KISHI, Jocelyn Yoshiko

IPC分类号： C12Q1/68 ,  C40B20/04 ,  C40B70/00 ,  C40B40/06

公开(公告)号：EP3853363A1

公开(公告)日：2021-07-28

申请号：EP19863047.7

申请日：2019-09-17

申请人： The University of Hong Kong

发明人： WONG, Alan Siu Lun ,  CHOI, Gigi Ching Gee

IPC分类号： C12N15/10 ,  C40B20/04

公开(公告)号：EP3253491B1

公开(公告)日：2021-03-24

申请号：EP16746208.4

申请日：2016-02-04

发明人： YANAI, Itai ,  SIVAN, Uri ,  BROD, Elad ,  HASHIMSHONY, Tamar ,  SENDEROVICH, Anatoly

IPC分类号： B01L3/00 ,  C12M3/00 ,  C12Q1/68 ,  C12N15/10 ,  C40B20/04 ,  G01N33/487 ,  C12Q1/6837

公开(公告)号：EP3790967A1

公开(公告)日：2021-03-17

申请号：EP19799951.9

申请日：2019-05-07

申请人： MGI Tech Co., Ltd. ,  BGI Shenzhen

发明人： DRMANAC, Radoje T. ,  PETERS, Brock A. ,  WANG, Ou

IPC分类号： C12N15/10 ,  C12N15/66 ,  C12N9/00 ,  C40B20/04 ,  C40B70/00

公开(公告)号：EP3259355B1

公开(公告)日：2020-11-25

申请号：EP16753115.1

申请日：2016-02-19

申请人： The Regents of the University of California

发明人： KOSURI, Sriram ,  CHEUNG, Rocky ,  LUBOCK, Nathan, B.

IPC分类号： C12N15/11 ,  C40B20/04 ,  C40B40/06

公开(公告)号：EP3524344A1

公开(公告)日：2019-08-14

申请号：EP19158398.8

申请日：2004-03-31

申请人： United Kingdom Research and Innovation

发明人： GRIFFITHS, Andrew David ,  ABELL, Chris ,  HOLLFELDER, Florian ,  MASTROBATTISTA, Enrico

IPC分类号： B01J19/00 ,  G01N33/543 ,  C07K1/04 ,  C12N15/10 ,  C40B20/04 ,  C40B30/04 ,  C40B50/08 ,  B82Y30/00 ,  B82Y10/00 ,  B82Y5/00 ,  C40B40/06 ,  C40B40/10

摘要： The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets. The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules.

公开(公告)号：EP3488018A1

公开(公告)日：2019-05-29

申请号：EP17831924.0

申请日：2017-07-21

申请人： President and Fellows of Harvard College

发明人： WOO, Sungwook ,  YIN, Peng

IPC分类号： C12Q1/68 ,  C40B20/04 ,  C40B30/04

公开(公告)号：EP2989239B1

公开(公告)日：2018-07-04

申请号：EP14788445.6

申请日：2014-04-23

申请人： Sutro Biopharma, Inc.

发明人： STAFFORD, Ryan ,  THANOS, Christopher, D

IPC分类号： C40B10/00 ,  C40B20/04 ,  C40B40/02 ,  C40B40/08

CPC分类号： G01N33/6857 ,  C07K16/00 ,  C07K16/3007 ,  C07K16/32 ,  C07K2317/14 ,  C07K2317/24 ,  C07K2317/55 ,  C07K2317/92

摘要： The invention relates to a method for generating and selecting Fab fragments using ribosomal display and cell-free protein synthesis. The invention also provides a ribosomal display reaction system for generating Fab fragment complexes. The compositions of a Fab fragment complex and a library thereof are also provided.

公开(公告)号：EP3204522A4

公开(公告)日：2018-06-20

申请号：EP15849440

申请日：2015-10-09

申请人： INVITAE CORP

发明人： KONVICKA KAREL ,  JACOBS KEVIN

IPC分类号： G06F19/22 ,  C40B20/00 ,  C40B20/04 ,  C40B40/06 ,  G06F19/18

CPC分类号： G06F19/18 ,  G06F19/22

摘要： Provided herein are novel methods, systems and processes of mapping and assembling sequence reads. Also provided herein are methods, systems and processes of identifying the presence or absence of a genetic variation in a genome of a subject.

公开(公告)号：EP2922989B1

公开(公告)日：2018-04-04

申请号：EP13857053.6

申请日：2013-11-25

申请人： The University of Toledo

发明人： WILLEY, James, C. ,  BLOMQUIST, Thomas ,  CRAWFORD, Erin

IPC分类号： C40B20/04 ,  C12Q1/68

CPC分类号： C12Q1/6806 ,  C12Q1/6851 ,  C12Q1/6869 ,  C40B20/04 ,  C12Q2545/107 ,  C12Q2535/122

摘要： Methods for standardized sequencing of nucleic acids and uses thereof are described. A method for controlling for non-systematic error in an amplification-based next generation sequencing (NGS) library preparation, comprises: including of an internal amplification control (IAC) sharing identical priming sites to a native nucleic acid target template of interest in a NGS library preparation; mimicing the kinetics of the native nucleic acid target in the amplification reaction, and controlling for sample-, platform-, experiment-, operator- and/or target-specific variation in amplification efficiency.