公开(公告)号：EP3065795A1

公开(公告)日：2016-09-14

申请号：EP14812011.6

申请日：2014-11-05

申请人： Flodesign Sonics Inc.

发明人： LIPKENS, Bart ,  BARNES, Jason ,  MEALEY, Dane ,  PRESZ, Walter M. Jr ,  KOWALSKI, Stanley, III ,  MASI, Louis ,  KENNEDY, Thomas J., III ,  MCCARTHY, Brian ,  ROSS-JOHNSRUD, Ben

IPC分类号： A61M1/36 ,  C12M1/26 ,  C12M1/00 ,  B60B1/00

CPC分类号： C12M47/02 ,  A61M1/3678 ,  B01D21/0045 ,  B01D21/283 ,  B06B1/06 ,  C12M33/08 ,  C12M47/10

摘要： An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a fluid.

摘要翻译： 公开了一种由模块化部件组成的消声装置。 本文公开了多个模块，包括超声换能器模块，输入/输出模块，收集井模块和各种连接器模块。 这些允许构建具有用于从流体分离颗粒（例如生物细胞）的适当流体动力学的不同系统。

公开(公告)号：EP2825279A4

公开(公告)日：2016-03-09

申请号：EP13760840

申请日：2013-03-15

申请人： FLODESIGN SONICS INC

发明人： LIPKENS BART ,  DIONNE JASON ,  KENNEDY III THOMAS J ,  MASI LOUIS ,  KOWALSKI III STANLEY

IPC分类号： B01D17/04 ,  B01D43/00 ,  C02F1/36 ,  C02F1/40

CPC分类号： B01D43/00 ,  B06B1/0644 ,  C12M47/02

摘要： A system having improved trapping force for acoustophoresis is described where the trapping force is improved by manipulation of the frequency of the ultrasonic transducer. The transducer includes a ceramic crystal. The crystal may be directly exposed to fluid flow. The crystal may be air backed, resulting in a higher Q factor.

公开(公告)号：EP2748110A4

公开(公告)日：2015-05-27

申请号：EP12825592

申请日：2012-08-22

申请人： FLODESIGN SONICS INC

发明人： DIONNE JASON ,  LIPKENS BART ,  RIETMAN EDWARD A

IPC分类号： B01D21/28 ,  B03B5/00 ,  C02F1/36

CPC分类号： B03B5/00 ,  B01D21/283 ,  C02F1/36 ,  C12M47/02

摘要： A flow chamber is provided through which is flowed a mixture of a fluid and a particulate. The flow chamber comprises at least one multi-phase water inlet through which multi-phase water enters the flow chamber, a water outlet through which water exits the flow chamber, a solids outlet through which particles having a density at or above a pre-defined threshold exit the flow chamber, and a low density outlet through which particles having a density below the pre-defined threshold exit the flow chamber. Also provided are one or more ultrasonic transducers and one or more reflectors corresponding to each transducer to acoustically filter the fluid and cause particles/fluid to be selectively diverted to one of the outlets. Related apparatus, systems, techniques and articles are also described.

公开(公告)号：EP2747863A4

公开(公告)日：2015-04-22

申请号：EP12826162

申请日：2012-08-22

申请人： FLODESIGN SONICS INC

发明人： RIETMAN EDWARD A ,  LIPKENS BART ,  DIONNE JASON

IPC分类号： B01D21/28 ,  C02F1/36 ,  C02F103/08

CPC分类号： C02F1/36 ,  B01D21/283 ,  B01D61/00 ,  B01D61/20 ,  B01D65/00 ,  B01D65/08 ,  B01D2321/2075 ,  C02F1/444 ,  C02F2103/08 ,  C02F2303/04 ,  C12M47/02

公开(公告)号：EP2838582A1

公开(公告)日：2015-02-25

申请号：EP13721179.3

申请日：2013-04-19

申请人： Flodesign Sonics Inc.

发明人： DUTRA, Brian ,  LIPKENS, Bart

IPC分类号： A61M1/38

CPC分类号： A61M1/3681 ,  A61M1/363 ,  A61M1/3678 ,  A61M2202/08 ,  B01D21/283

摘要： A system for removing lipids from blood during cardiopulmonary bypass surgery is disclosed. The system uses an acoustophoretic separator having improved trapping force. The transducer of the acoustophoretic seperator includes a ceramic crystal. Blood flows through the separator, and lipids are trapped and removed.

摘要翻译： 公开了一种在体外循环手术期间从血液中除去脂质的系统。 该系统使用具有改进的捕获力的声学分离器。 声波分离器的换能器包括陶瓷晶体。 血液流过分离器，脂质被捕获并除去。

公开(公告)号：EP2825279A1

公开(公告)日：2015-01-21

申请号：EP13760840.2

申请日：2013-03-15

申请人： Flodesign Sonics Inc.

发明人： LIPKENS, Bart ,  DIONNE, Jason ,  KENNEDY, III, Thomas J. ,  MASI, Louis ,  KOWALSKI, III, Stanley

IPC分类号： B01D43/00

CPC分类号： B01D43/00 ,  B06B1/0644 ,  C12M47/02

摘要： A system having improved trapping force for acoustophoresis is described where the trapping force is improved by manipulation of the frequency of the ultrasonic transducer. The transducer includes a ceramic crystal. The crystal may be directly exposed to fluid flow. The crystal may be air backed, resulting in a higher Q factor.

公开(公告)号：EP2558179A4

公开(公告)日：2013-10-23

申请号：EP11769474

申请日：2011-04-12

申请人： FLODESIGN SONICS INC

发明人： DIONNE JASON ,  LIPKENS BART ,  RIETMAN EDWARD A

IPC分类号： B01D17/02 ,  C02F1/36 ,  C02F1/40

CPC分类号： C02F1/36 ,  B01D17/04 ,  B01D17/044 ,  B01D21/28 ,  C02F1/40 ,  C02F2101/325 ,  C02F2103/008 ,  C02F2103/10 ,  C02F2303/04

摘要： Several prototype systems are described for separating oil and water from emulsions. The systems operate at ultrasonic resonance and are thus low power. Each system contains one or more acoustic transducers operating in the 100 kHz to 5 MHz range. Each system contains flow input for the emulsion and two or more flow outputs for the separated oil and water. Existing prototypes operate from 200 mL/min to >15 L/min. Each uses low power in the range of 1-5 W.

公开(公告)号：EP2214098B1

公开(公告)日：2011-10-05

申请号：EP10004699.4

申请日：2003-04-30

申请人： Sonics, Inc.

发明人： Wingard, Drew E. ,  Chou, Chien Chum ,  Masri, Nabil N. ,  O'Connell, Thomas W. ,  Tomlinson, Jay S.

IPC分类号： G06F9/00 ,  H04L29/06

CPC分类号： H04L69/16 ,  H04L29/06 ,  H04L67/28 ,  H04L67/2823 ,  H04L69/163

公开(公告)号：EP1435043A4

公开(公告)日：2010-04-21

申请号：EP02709659

申请日：2002-02-21

申请人： SONICS INC

发明人： WEBER WOLF-DIETRICH

IPC分类号： G06F12/00 ,  G06F13/14 ,  G06F9/48 ,  G06F13/36 ,  G06F13/362 ,  G06F13/364 ,  H04B7/212 ,  H04L12/56

CPC分类号： G06F9/4887 ,  G06F13/364 ,  H04L47/24 ,  H04L47/521 ,  H04L47/525 ,  H04L47/6215 ,  H04L47/6265 ,  H04L47/6275 ,  H04L67/322

公开(公告)号：EP2160762A1

公开(公告)日：2010-03-10

申请号：EP08780967.9

申请日：2008-06-25

申请人： Sonics, INC. ,  Wingard, Drew E. ,  Chou, Chien-Chun ,  Hamilton, Stephen W. ,  Swarbrick, Ian Andrew ,  Vakilotojar, Vida

发明人： WINGARD, Drew E. ,  CHOU, Chien-Chun ,  HAMILTON, Stephen W. ,  SWARBRICK, Ian Andrew ,  VAKILOTOJAR, Vida

IPC分类号： H01L25/00

CPC分类号： G11C7/1072 ,  G06F12/0607 ,  G06F15/17375 ,  Y02D10/13

摘要： A method, apparatus, and system are described, which generally relate to an interconnect routing transactions to target IP cores, including two or more channels making up a first aggregate target. The two or more channels populate an address space assigned to the first aggregate target and appear as a single target to the initiator IP cores. The interconnect implements chopping logic to chop an individual transaction from a first initiator IP core whose address sequence crosses a channel address boundary from a first channel to a second channel within the first aggregate target into two or more burst transactions. A first chopped burst transaction is chopped to fit within the address boundaries of the first channel and a second chopped burst transaction is chopped to fit within the address boundaries of the second channel.