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    METHOD FOR THIN FILM THERMOELECTRIC MODULE FABRICATION
    72.
    发明公开
    METHOD FOR THIN FILM THERMOELECTRIC MODULE FABRICATION 审中-公开
    用于生产热电模块

    公开(公告)号：EP2471114A2

    公开(公告)日：2012-07-04

    申请号：EP10765908.8

    申请日：2010-10-05

    申请人： The Board of Regents of the University of Oklahoma

    发明人： McCANN, Patrick, John

    IPC分类号： H01L35/34 ,  H01L35/08 ,  H01L21/76

    CPC分类号： H01L35/34 ,  H01L35/08

    摘要： Methods of fabrication of a thermoelectric module from thin film thermoelectric material are disclosed. In general, a thin film thermoelectric module is fabricated by first forming an N-type thin film thermoelectric material layer and one or more metallization layers on a substrate. The one or more metallization layers and the N-type thin film thermoelectric material layer are etched to form a number of N-type thermoelectric material legs. A first electrode assembly is then bonded to a first portion of the N-type thermoelectric material legs, and the first electrode assembly including the first portion of the N-type thermoelectric material legs is removed from the substrate. In a similar manner, a second electrode assembly is bonded to a first portion of a number of P-type thermoelectric material legs. The first and second electrode assemblies are then bonded using a flip-chip bonding process to complete the fabrication of the thermoelectric module.

    Inhibition of reactive oxygen species and protection of mammalian cells
    74.
    发明公开
    Inhibition of reactive oxygen species and protection of mammalian cells 审中-公开
    Hemmung reaktiver Sauerstoffspezies und Schutz vonSäugerzellen

    公开(公告)号：EP2359907A1

    公开(公告)日：2011-08-24

    申请号：EP10181322.8

    申请日：2006-04-27

    申请人： University of Central Florida Research Foundation, Inc. ,  THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA

    发明人： Seal, Sudipta ,  Patil, Swanand ,  Sezate, Steve ,  Wong, Lily ,  Chen, Junping ,  McGinnis, James F.

    IPC分类号： A61P27/02 ,  A61K33/24

    CPC分类号： A61K33/24

    摘要： Methods and compositions useful for neuronal protection in retinal cells in vitro and the protection of mammalian cells from reactive oxygen species in vivo are provided. UltrafÊne nano-size cerium oxide particles, less than 10 nanometers in diameter, have been provided to decrease reactive oxygen species (ROS) in retina tissue that generates large amounts of ROS. These reactive oxygen species (ROS) are involved in light- induced retina degeneration and age-related macular degeneration (AMD). Cerium oxide nanoparticles have been used to promote the lifespan of retinal neurons and protect the neurons from apoptosis induced by hydrogen peroxide in vitro and in vivo. The neuronal protection in retinal cells is achieved by decreasing generation of intracellular reactive oxygen species (ROS). Thus, cerium oxide particles are used to promote the longevity of retinal neurons in vitro and mammalian cells in vivo.

    摘要翻译： 提供了可用于体外视网膜细胞神经元保护的方法和组合物，以及哺乳动物细胞在活体氧中体内的保护。 已经提供了直径小于10纳米的超细纳米尺寸氧化铈颗粒，以减少产生大量ROS的视网膜组织中的活性氧（ROS）。 这些活性氧（ROS）参与光诱导的视网膜变性和年龄相关性黄斑变性（AMD）。 已经使用氧化铈纳米粒子来促进视网膜神经元的寿命，并保护神经元免受体外和体内过氧化氢诱导的细胞凋亡。 通过减少细胞内活性氧（ROS）的产生来实现视网膜细胞中的神经元保护。 因此，氧化铈颗粒用于在体外和哺乳动物细胞体内促进视网膜神经元的寿命。

    METHOD AND APPARATUS FOR COMPACTION OF ROADWAY MATERIALS
    75.
    发明公开
    METHOD AND APPARATUS FOR COMPACTION OF ROADWAY MATERIALS 审中-公开
    方法和装置压实巷道材料的

    公开(公告)号：EP2324336A1

    公开(公告)日：2011-05-25

    申请号：EP09812118.9

    申请日：2009-09-01

    申请人： The Board of Regents of the University of Oklahoma

    发明人： COMMURI, Sesh

    IPC分类号： G01N9/00

    摘要： A method of compacting a roadway section includes entering initial input parameters into a compaction analyzer, A plurality of passes is made with a roller over a portion of the roadway section and vibratory energy is applied thereto. Responsive vibration signals are gathered and the compaction analyzer generates estimated density signals. Actual density measurements are taken and the estimated densities are compared thereto. Selected ones of the initial input parameters are adjusted so that an adjusted density output signal which represents the actual density of a roadway section is generated.

    Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus
    76.
    发明公开
    Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus 审中-公开
    使用细胞因子测定来诊断，治疗和评估系统性红斑狼疮的方法

    公开(公告)号：EP2287616A1

    公开(公告)日：2011-02-23

    申请号：EP10176365.4

    申请日：2004-09-15

    申请人： Oklahoma Medical Research Foundation ,  THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA

    发明人： Woodward, Cherie M. ,  Centola, Michael B. ,  Alex, Philip J. ,  Hensley, Kenneth

    IPC分类号： G01N33/68

    CPC分类号： G01N33/6863 ,  G01N33/564 ,  G01N2800/104 ,  G01N2800/24 ,  G01N2800/52

    摘要： The invention provides a method for aiding in the diagnosis of irritable bowel syndrome (IBS), said method comprising the steps of:
    (a) measuring the level of a cytokine within a sample previously obtained from a patient using an assay system or assay device;
    (b) comparing the measured cytokine level of the sample with a pre-defined level of the cytokine found in normal or inflammatory states;
    (c) determining if the patient has IBS based on the comparison in step (b); and
    (d) reporting the determination to the patient or a clinician.

    摘要翻译： 本发明提供了一种帮助诊断肠易激综合征（IBS）的方法，所述方法包括以下步骤：（a）使用化验系统或化验装置测量先前从患者获得的样品内细胞因子的水平; （b）将所测量的样品的细胞因子水平与在正常或炎症状态中发现的预定义水平的细胞因子进行比较; （c）基于步骤（b）中的比较确定患者是否患有IBS; 和（d）将测定结果报告给患者或临床医师。