COMPOSITE BIOMARKERS FOR NON-INVASIVE SCREENING, DIAGNOSIS AND PROGNOSIS OF COLORECTAL CANCER
    84.
    发明公开
    COMPOSITE BIOMARKERS FOR NON-INVASIVE SCREENING, DIAGNOSIS AND PROGNOSIS OF COLORECTAL CANCER 有权
    VERBUNDBIOMARKERFÜRNICHTINVASIVES SCREENING,DIAGNOSE UND PROGNOSE VON KOLOREKTALKARZINOM

    公开(公告)号:EP2768980A2

    公开(公告)日:2014-08-27

    申请号:EP12813096.0

    申请日:2012-10-16

    IPC分类号: C12Q1/68

    摘要: The present invention concerns particular biomarkers for diagnosing and/or prognosticating colorectal cancer, in particular in a non-invasive manner. The methods and compositions concern analysis of methylation patterns of one or more genes from a set of 29 genes identified as described herein. In certain embodiments, the gene set includes at least P15.INK4b, SST, GAS7, CNRIP1, and PIK3CG.

    摘要翻译: 本发明涉及用于诊断和/或预后结直肠癌的特定生物标志物,特别是以非侵入性方式。 所述方法和组合物涉及从如本文所述鉴定的一组29个基因中的一个或多个基因的甲基化模式的分析。 在某些实施方案中,所述基因组包括至少P15.INK4b,SST,GAS7,CNRIP1和PIK3CG。