公开(公告)号：EP2619329B1

公开(公告)日：2019-05-22

申请号：EP11827484.4

申请日：2011-09-21

申请人： The Board of Trustees of the Leland Stanford Junior University

发明人： MYLLYKANGAS, Samuel ,  BUENROSTRO, Jason ,  JI, Hanlee P.

IPC分类号： C12Q1/68 ,  C40B40/06

公开(公告)号：EP2068761B1

公开(公告)日：2019-02-13

申请号：EP07837089.7

申请日：2007-08-20

申请人： Cook Medical Technologies LLC

发明人： HARTLEY, David, Ernest ,  DUCKE, Werner, D.

IPC分类号： A61F2/07

公开(公告)号：EP2659860B1

公开(公告)日：2018-11-28

申请号：EP13275106.6

申请日：2013-05-01

申请人： Cook Medical Technologies LLC

发明人： Hartley, David Ernest ,  Roeder, Blayne ,  Ducke, Werner ,  Kasprzak, Piotr Miroslaw

IPC分类号： A61F2/07 ,  A61F2/966

CPC分类号： A61F2/962 ,  A61F2/07 ,  A61F2/848 ,  A61F2/89 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/077 ,  A61F2002/8483 ,  A61F2002/9511 ,  A61F2250/006

摘要： A stent graft adaptor (10) has an outer graft tube (12) and an inner graft tube (14) with the inner graft (14) tube substantially concentric with and within the outer graft tube (12). A joining member (16) extends between the inner graft tube (14) and the outer graft tube (12). The joining member (16) can be a continuous fold of graft material extending from a proximal end of the outer tube (12) to a proximal end of the inner tube (14). The inner graft tube (14) has at least one self-expanding stent (24) on an outer surface thereof and the outer graft tube has at least one self-expanding stent (18) on an inner surface. The outer surface of the outer graft tube (12) provides a sealing surface to engage against the wall of a vessel and the inner tube (14) provides a sealing surface (26) to engage with a corresponding sealing surface of a stent graft deployed through it. The outer sealing surface can include barbs (22) to engage with the vasculature.

公开(公告)号：EP2666512B1

公开(公告)日：2018-11-14

申请号：EP13275113.2

申请日：2013-05-08

申请人： Cook Medical Technologies LLC

发明人： Roeder, Blayne ,  Kasprzak, Piotr Miroslaw ,  Ducke, Werner

IPC分类号： A61B17/02 ,  A61M39/06

CPC分类号： A61B17/0218 ,  A61M39/0606 ,  A61M2039/0626 ,  A61M2039/064 ,  A61M2039/066 ,  F04C2270/0421

摘要： An endoscopic access port and sheath assembly or laparoscopic port (10) comprises a sheath (12) and a haemostatic valve. The sheath has an elongate tubular body and a sheath lumen through it. The haemostatic valve comprises a housing (14) and the housing comprises a tubular body with an internal lumen (18). A first end of the housing (14) is connected to the sheath, and the sheath lumen and the internal lumen are in fluid communication. The second end of the housing (14) has an access aperture. There is a substantially cylindrical valve assembly (27) within the housing (14) at the second end of the housing (14). The substantially cylindrical valve assembly (27) is formed from a plurality of valve segments (28). Each valve segment (28) has an elongate body being in cross-section a sector of a circle. Each valve segment (28) is formed from a resilient material. The plurality of valve segments (28), when assembled, form the substantially cylindrical valve assembly (27) and define between each other a plurality of resilient interface regions (29) to receive and grip a medical device between them in use.

公开(公告)号：EP1684668B1

公开(公告)日：2018-10-17

申请号：EP04818690.2

申请日：2004-11-08

申请人： Cook Medical Technologies LLC

发明人： BOATMAN, Scott, E. ,  SCHAEFFER, Darin, G. ,  HOFFA, Michael, C.

IPC分类号： A61F2/06

CPC分类号： A61F2/954 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61F2/064 ,  A61F2/07 ,  A61F2/856 ,  A61F2/88 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/821 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/9511 ,  A61F2210/0076 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/0097 ,  A61F2250/0098

摘要： An endoluminal vascular repair system includes an aorta stent graft having a fenestration with a first reinforcement around the fenestration. The fenestration aligns with a branch vessel when deployed. A branch vessel stent graft has a flaring portion at a proximal end of the branch vessel prosthesis that has a second reinforcement around its circumference to engage the reinforcement around the fenestration, and a tubular portion. When deployed, the flaring portion retains the proximal end within the aorta stent graft, and the tubular portion extends through the fenestration and into the branch vessel.

公开(公告)号：EP2508213B1

公开(公告)日：2018-03-28

申请号：EP12175380.0

申请日：2005-12-08

申请人： Cook Medical Technologies LLC

发明人： Carlgren, Fredrik ,  Guenther, Rolf, W.

IPC分类号： A61L27/40

CPC分类号： A61K49/18 ,  A61L27/54 ,  A61L29/18 ,  A61L31/10 ,  A61L31/18 ,  A61L2300/404 ,  A61L2300/44 ,  A61L2300/452 ,  A61L2300/61

摘要： A medical device is disclosed wherein a contrast agent is incorporated into the actual device. The medical device is generally comprised of a base material forming the structure of the device and a contrast agent, such as tocopherol and tocopherol derivative solutions or suspensions, gadolinium, or nickel sulfate integrated into the base material itself or posited on a substantial portion of an exterior surface of the device. The device may include other additional functional agents and layers.

公开(公告)号：EP2007868B1

公开(公告)日：2017-01-18

申请号：EP07758900.0

申请日：2007-03-20

申请人： Gusmer Enterprises, Inc.

发明人： WALKER, Teresa, L. ,  PETERSEN, Lars ,  MENZIES, Robert, H.

IPC分类号： C12G1/02 ,  C12G3/02 ,  C12P7/06

CPC分类号： C12G1/04 ,  C12G1/0203 ,  C12H1/14 ,  C12M29/00 ,  Y02E50/17

公开(公告)号：EP1996089B8

公开(公告)日：2016-10-12

申请号：EP07753512.8

申请日：2007-03-20

申请人： Cook Medical Technologies LLC

发明人： HARTLEY, David, Ernest ,  IVANCEV, Krasnodar ,  DUCKE, Werner, D. ,  DEBRUYNE, Michael, P. ,  DIAMOND, Jarett ,  FRYE, Mark, R.

IPC分类号： A61B17/22

CPC分类号： A61B17/221 ,  A61B2017/00867 ,  A61B2017/2215

公开(公告)号：EP2497444B1

公开(公告)日：2015-09-16

申请号：EP12171060.2

申请日：2006-08-18

申请人： Cook Medical Technologies LLC

发明人： Hartley, David Ernest ,  Lawrence-Brown, Michael ,  Anderson, John, Lennon

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/075 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0039

公开(公告)号：EP2598659B1

公开(公告)日：2015-03-11

申请号：EP11813024.4

申请日：2011-07-25

申请人： Genomic Health, Inc.

发明人： SHAK, Steven ,  BAEHNER, Frederick, L. ,  MADDALA, Tara ,  LEE, Mark ,  PELHAM, Robert, J. ,  COWENS, Wayne ,  CHERBAVAZ, Diana ,  KIEFER, Michael, C. ,  CRAGER, Michael ,  GODDARD, Audrey ,  BAKER, Joffre, B.

IPC分类号： C12Q1/68 ,  G01N33/574

CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178 ,  G06F19/00

摘要： Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.