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1.发明公开IMPROVED CARBON DIOXIDE FIXATION VIA BYPASSING FEEDBACK REGULATION 审中-公开VERBESSERTE KOHLENDIOXIDFIXIERUNG MITTELSRÜCKKOPPLUNGSREGULIERUNGSUMGEHUNG
公开(公告)号：EP3099784A1
公开(公告)日：2016-12-07
申请号：EP15743189.1
申请日：2015-01-30
摘要： Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
摘要翻译： 提出了基因工程细胞和方法，允许从二氧化碳生产各种价值产品。 考虑的细胞具有遗传修饰的CBB循环，使得在CBB循环中固定的两个分子的CO 2可以作为单一的C2化合物从经修饰的CBB循环中排出。 在预期的方面，CBB循环包括从CBB循环的化合物产生单一C2化合物的酶活性，而对CBB循环的进一步修饰将不会在CBB循环中已经存在的催化活性之外引入另外的重组酶活性/活性 。
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公开(公告)号：EP2773761B1
公开(公告)日：2019-03-06
申请号：EP12845783.5
申请日：2012-11-02
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公开(公告)号：EP2686432B1
公开(公告)日：2018-12-26
申请号：EP12758227.8
申请日：2012-03-14
IPC分类号： C12P7/02 , C12P7/24 , C12P7/16 , C12N9/04 , C12N9/10 , C12N15/52 , C12N15/67 , C12N15/70 , C12N15/74 , C12N1/16 , C12N9/88 , C12N1/20
CPC分类号： C12P7/16 , C07C29/141 , C07C31/125 , C12N1/16 , C12N1/20 , C12N9/0006 , C12N9/1022 , C12N9/88 , C12N15/52 , C12N15/63 , C12N15/67 , C12N15/70 , C12N15/74 , C12P7/02 , C12P7/24 , Y02E50/16 , Y02E50/17 , C07C31/08 , C07C31/10 , C07C31/12
摘要： An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.
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公开(公告)号：EP2686432A2
公开(公告)日：2014-01-22
申请号：EP12758227.8
申请日：2012-03-14
CPC分类号： C12P7/16 , C07C29/141 , C07C31/125 , C12N1/16 , C12N1/20 , C12N9/0006 , C12N9/1022 , C12N9/88 , C12N15/52 , C12N15/63 , C12N15/67 , C12N15/70 , C12N15/74 , C12P7/02 , C12P7/24 , Y02E50/16 , Y02E50/17 , C07C31/08 , C07C31/10 , C07C31/12
摘要： An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.
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公开(公告)号：EP3099784B1
公开(公告)日：2020-03-04
申请号：EP15743189.1
申请日：2015-01-30
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公开(公告)号：EP2773761A1
公开(公告)日：2014-09-10
申请号：EP12845783.5
申请日：2012-11-02
CPC分类号： C12P7/16 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N15/52 , C12P7/24 , C12Y101/01157 , C12Y102/01057 , C12Y103/01086 , C12Y203/01009
摘要： Microorganisms and methods of producing n-butyraldehyde with enhanced yields are presented in which a microorganism is engineered to enhance the conversion of a carbon source into n-butyraldehyde. The n-butyraldehyde is recovered by way of a gas stripping process that occurs during the conversion process, providing significantly greater product yield than post-fermentation recovery of n-butyraldehyde alone.
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