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    FLOW SPEED MEASURING DEVICE, ANTIGEN CONCENTRATION MEASURING DEVICE, FLOW CELL, FLOW SPEED MEASURING METHOD, AND ANTIGEN CONCENTRATION MEASURING METHOD
    10.
    发明公开
    FLOW SPEED MEASURING DEVICE, ANTIGEN CONCENTRATION MEASURING DEVICE, FLOW CELL, FLOW SPEED MEASURING METHOD, AND ANTIGEN CONCENTRATION MEASURING METHOD 审中-公开
    流量计，抗原浓度计，流通池，进行流量测量方法和方法抗原浓度测量

    公开(公告)号：EP2237022A4

    公开(公告)日：2011-02-23

    申请号：EP09702693

    申请日：2009-01-15

    申请人： NIPPON TELEGRAPH & TELEPHONE

    发明人： IWASAKI YUZURU ,  HORIUCHI TSUTOMU ,  SEYAMA MICHIKO ,  MIURA TORU ,  HAGA TSUNEYUKI ,  TAKAHASHI JUN-ICHI ,  HAYASHI TSUYOSHI

    IPC分类号： G01N21/27 ,  G01F1/708 ,  G01N21/05 ,  G01N21/41 ,  G01P5/18

    CPC分类号： G01N21/75 ,  G01F1/704 ,  G01F1/712 ,  G01F1/8468 ,  G01N21/553 ,  G01P5/18

    摘要： A flow rate measurement apparatus includes a light oscillator; a thin metallic film which causes surface plasmon resonance by light output from the light oscillator; a focusing unit which fixes the thin metallic film and converts the output light of the light oscillator into incident light having a plurality of incident angles to focus the incident light at a location of a focal line in a straight line shape on the thin metallic film; a measurement part having antibody fixed areas to which an antibody is fixed and reference areas to which an antibody is not fixed, the antibody fixed areas and the reference areas being alternately arranged at a location along the focal line location on the thin metallic film; a light receiver which receives reflected light, at the focal line location, of the output light by surface plasmon resonance occurring at the focal line location, at each of the plurality of incident light angles; an SPR angle calculator which obtains a temporal change of an SPR angle in each of the antibody fixed areas and the reference areas in the measurement part; and a flow rate operation unit which calculates the flow rate of the sample flowing in the flow cell based on the temporal change of the SPR angle obtained by the SPR angle calculator.

    摘要翻译： 一种流量测量装置包括：光振荡器; 薄金属膜通过从所述光振荡器输出光引起表面等离子体共振; 的聚焦部，其固定所述金属薄膜和光振荡器的输出光转换成具有入射角的多个以在所述薄金属成膜的直线形状的焦线的位置以聚焦入射光的入射光; 的抗体固定区和参考区，以该抗体的不固定，所述抗体固定区域和参考区域被沿着所述薄金属成膜的焦线位置的位置交替地布置一个具有测量部分抗体固定区域到哪个; 光接收器通过表面等离子体共振在焦线位置处发生，在各入射的光的角度的多个，接收反射的光，在所述焦点线位置的输出光的; 在用于获得在每个抗体固定区域，并在测定部的参考区域的SPR角的时间变化SPR角计算器; 和其计算在基于由所述SPR角计算器获得的SPR角的时间变化的流动池流动的样品的流速的流速运算部。