公开(公告)号：EP2623106A4

公开(公告)日：2014-03-26

申请号：EP10857831

申请日：2010-09-29

申请人： SHISEIDO CO LTD

发明人： YOSHIDA YUZO ,  SOMA TSUTOMU ,  FUJIWARA SHIGEYOSHI

IPC分类号： C12N5/071 ,  A61K35/36 ,  A61P17/14

CPC分类号： A01K67/027 ,  A01K67/0271 ,  A01K2207/12 ,  A01K2227/105 ,  A01K2267/03 ,  A61K8/985 ,  A61K35/36 ,  A61K2800/70 ,  A61L27/3813 ,  A61L2430/18 ,  A61Q7/00 ,  C12N5/0627 ,  C12N5/0628

摘要： A composition for regenerating the follicle, which contains CD36-expressing connective tissue sheath cells (DSc).

公开(公告)号：EP2034011A4

公开(公告)日：2009-11-25

申请号：EP07768103

申请日：2007-06-27

申请人： SHISEIDO CO LTD

发明人： FUJIWARA SHIGEYOSHI ,  KISHIMOTO JIRO ,  SOMA TSUTOMU

IPC分类号： A61L27/00 ,  C12N5/071 ,  C12N5/077

CPC分类号： C12N5/0697 ,  C12N5/0625 ,  C12N5/0627 ,  C12N5/0629 ,  C12N5/0666 ,  C12N2501/40 ,  C12N2501/415

公开(公告)号：EP2653534A4

公开(公告)日：2014-05-14

申请号：EP11848080

申请日：2011-12-07

申请人： SHISEIDO CO LTD

发明人： FUJIWARA SHIGEYOSHI ,  TAKEI KEIGO ,  SUDA YUKIMITSU

IPC分类号： C12N5/071 ,  C12M1/22 ,  C12Q1/02

CPC分类号： G01N33/502 ,  C12M23/20 ,  C12M35/08 ,  C12N5/0068 ,  C12N5/0667 ,  C12N5/0671 ,  C12N5/0693 ,  C12N2533/30 ,  G01N33/5032 ,  G01N33/5082

公开(公告)号：EP2444477A4

公开(公告)日：2013-01-09

申请号：EP10789497

申请日：2010-06-15

申请人： SHISEIDO CO LTD

发明人： FUJIWARA SHIGEYOSHI ,  TAKEI KEIGO ,  HIRAYAMA AYA ,  SUDA YUKIMITSU

IPC分类号： C12M1/00 ,  C08J7/04 ,  C08J7/12 ,  C09D133/14 ,  C12M3/00 ,  C12N5/07

CPC分类号： C12M23/20 ,  C12N5/062 ,  C12N5/0667 ,  C12N5/0671 ,  C12N5/0693 ,  C12N2533/30 ,  G01N33/5082

摘要： A container for forming a cell aggregate is provided in which a group represented by a general formula of: (in the formula, each of R 1 , R 2 , and R 3 is independently a an alkyl group with a carbon number of 1 or more and 6 or less and m is an integer of 2 or more and 6 or less.) and at least one of an amino group, a carboxyl group, and a hydroxyl group are present near a surface thereof.

公开(公告)号：EP2239324A4

公开(公告)日：2012-05-30

申请号：EP09703915

申请日：2009-01-21

申请人： SHISEIDO CO LTD

发明人： ISHIMATSU YUMIKO ,  IRIYAMA SHUNSUKE ,  FUJIWARA SHIGEYOSHI ,  SOMA TSUTOMU ,  KISHIMOTO JIRO

IPC分类号： C12N15/00 ,  C12N5/10 ,  C12N15/09 ,  C12R1/91

CPC分类号： C12N5/0693 ,  C07K14/475 ,  C12N5/0627 ,  C12N2501/415 ,  C12N2510/02

公开(公告)号：EP1504743A4

公开(公告)日：2009-09-09

申请号：EP03745443

申请日：2003-03-28

申请人： SHISEIDO CO LTD

发明人： FUJIWARA SHIGEYOSHI ,  DENDA MITSUHIRO ,  OGAWA KATSUKI ,  MIYAMOTO TSUYOSHI ,  TAKATA SADAKI

IPC分类号： A61K8/19 ,  A61K8/23 ,  A61K8/27 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/00 ,  A61K7/48

CPC分类号： A61Q1/12 ,  A61K8/022 ,  A61K8/19 ,  A61K8/23 ,  A61K8/27 ,  A61K2800/412 ,  A61K2800/651 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/08

摘要： An insoluble powder characterized by having a ξ potential which is a negative value. The insoluble powder preferably comprises barium sulfate as the main component. The insoluble powder preferably has an average primary-particle diameter of 3 to 100 µm and an aspect ratio of from 3 to 250. The insoluble powder preferably is a metal-doped barium sulfate powder obtained by reacting barium ions with sulfate ions in the presence of metal ions. In the above insoluble powder, the metal ions preferably are ions of one or more members selected from the group of lithium, sodium, and zinc. Also provided are a powder for restoring the barrier function of the skin and a powder for preventing/mitigating skin chapping which each is characterized by comprising the insoluble powder. Further provided is a preparation for external use on the skin, characterized by containing the insoluble powder in an amount of 1 to 40 wt.%.

公开(公告)号：EP1411354A4

公开(公告)日：2005-02-09

申请号：EP02733440

申请日：2002-06-10

申请人： SHISEIDO CO LTD

发明人： INOUE KAORI ,  FUJIWARA SHIGEYOSHI ,  DENDA MITSUHIRO ,  DENDA SUMIKO

IPC分类号： A61K49/00 ,  A61P17/00 ,  C12Q1/02 ,  G01N33/15 ,  G01N33/50 ,  G01N33/68 ,  G01N33/84 ,  A61K45/00

CPC分类号： G01N33/5044 ,  A61K49/0006 ,  G01N33/5008 ,  G01N33/502 ,  G01N33/6872 ,  G01N33/84

摘要： As the results of a study on an invasive stimulation receptor, it is found out that this stimulation receptor exists in epidermal cells, etc. and changes are observed in intracellular calcium concentration depending on the state of this stimulation receptor. Namely, a method of detecting a skin stimulation effect based on the relation between the stimulation effect of a test substance which are in contact with epithelial cells such as epidermal cells and an increase/decrease in calcium ion concentration in the epithelial cells.