Abstract:
A method of processing reaction mixtures in parallel, comprising: forming chemical reaction mixtures in a plurality of reactor vessels of a parallel reactor apparatus said apparatus comprising sensors for providing measured values relating to chemical reactions in said reactor vessels, and a processor for receiving data relating to said measured values; sealing the reaction mixture in each reactor vessel against fluid communication with the other vessels and at a pressure different than ambient pressure; injecting a fluid into at least one of the reactor vessels while the reaction mixture in said at least one vessel is sealed and at a pressure different than ambient pressure; agitating the reaction mixtures for at least a portion of the sealing step; and using the processor to receive said data relating to said measured values of the chemical reactions in said reactor vessels.
Abstract:
A reactor control system which monitors sensors providing measured values relating to a plurality of reactor vessels of a combinatorial reactor when used in a combinatorial chemical reaction, said system comprising: (a) a receiver for receiving the measured value associated with the contents of each of the plurality of reactor vessels during the course of the combinatorial chemical reaction; and (b) a display for simultaneously displaying during the course of the combinatorial chemical reaction the received measured values, said display comprising a tabular array corresponding to the plurality of reactor vessels.
Abstract:
Apparatus for parallel processing of reaction mixtures comprising a reactor block having a series of wells therein extending from an exterior surface of the block, a removable plate removably secured to the reactor block face-to-face with said exterior surface, the removable plate having openings therein in registry with the wells in the reactor block, removable liners in the wells for containing the reaction mixtures, a temperature control system for regulating the temperature of the reaction mixtures, and a stirring system attached to the removable plate and removable with the removable plate for agitating the reaction mixtures, the stirring system comprising spindles extending into respective wells, each of the spindles having a first end and a second end, stirring blade attached to the first end of each of the spindles, a drive mechanism located external to the vessels that is adapted to rotate the spindles, and magnetic feed through devices for magnetically coupling the drive mechanism to the second end of each of the spindles.
Abstract:
A method of processing reaction mixtures in parallel, comprising: forming chemical reaction mixtures in a plurality of reactor vessels of a parallel reactor apparatus said apparatus comprising sensors for providing measured values relating to chemical reactions in said reactor vessels, and a processor for receiving data relating to said measured values; sealing the reaction mixture in each reactor vessel against fluid communication with the other vessels and at a pressure different than ambient pressure; injecting a fluid into at least one of the reactor vessels while the reaction mixture in said at least one vessel is sealed and at a pressure different than ambient pressure; agitating the reaction mixtures for at least a portion of the sealing step; and using the processor to receive said data relating to said measured values of the chemical reactions in said reactor vessels.
Abstract:
Apparatus for parallel processing of reaction mixtures comprising a reactor block having a series of wells therein extending from an exterior surface of the block, a removable plate removably secured to the reactor block face-to-face with said exterior surface, the removable plate having openings therein in registry with the wells in the reactor block, removable liners in the wells for containing the reaction mixtures, a temperature control system for regulating the temperature of the reaction mixtures, and a stirring system attached to the removable plate and removable with the removable plate for agitating the reaction mixtures, the stirring system comprising spindles extending into respective wells, each of the spindles having a first end and a second end, stirring blade attached to the first end of each of the spindles, a drive mechanism located external to the vessels that is adapted to rotate the spindles, and magnetic feed through devices for magnetically coupling the drive mechanism to the second end of each of the spindles.
Abstract:
A reactor control system which monitors sensors providing measured values relating to a plurality of reactor vessels of a combinatorial reactor when used in a combinatorial chemical reaction, said system comprising: (a) a receiver for receiving the measured value associated with the contents of each of the plurality of reactor vessels during the course of the combinatorial chemical reaction; and (b) a display for simultaneously displaying during the course of the combinatorial chemical reaction the received measured values, said display comprising a tabular array corresponding to the plurality of reactor vessels.