公开(公告)号：EP3298388A1

公开(公告)日：2018-03-28

申请号：EP16727584.1

申请日：2016-05-20

Applicant: Quantum-si Incorporated

Inventor： ROTHBERG, Jonathan, M. ,  SICKLER, Jason, W. ,  WEST, Lawrence, C. ,  AHMAD, Faisal ,  GLENN, Paul, E. ,  JEWELL, Jack ,  GLENN, John ,  CAMARA, Jose ,  JORDAN, Jeremy, Christopher ,  REARICK, Todd ,  GHASEMI, Farshid ,  SCHULTZ, Jonathan, C. ,  FIFE, Keith, G.

IPC: G01N21/64 ,  H01S5/06 ,  C12Q1/00

CPC classification number: G01N21/6454 ,  C12Q1/00 ,  C12Q1/68 ,  C12Q1/6869 ,  G01N21/6402 ,  G01N21/6408 ,  G01N2201/0697 ,  H01S3/0092 ,  H01S3/025 ,  H01S3/0405 ,  H01S3/0809 ,  H01S3/0813 ,  H01S3/0815 ,  H01S3/09415 ,  H01S3/109 ,  H01S3/1118 ,  H01S3/1611 ,  H01S3/1653 ,  H01S3/1673 ,  H01S5/042 ,  H01S5/0657 ,  H01S5/14 ,  H01S5/146 ,  C12Q2523/313 ,  C12Q2561/12

Abstract: Apparatus and methods for producing ultrashort optical pulses (1-110) are described. A high-power, solid-state, passively mode- locked laser (1-110) can be manufactured in a compact module that can be incorporated into a portable instrument for biological or chemical analyses. The pulsed laser may produce sub-100-ps optical pulses at a repetition rate commensurate with electronic data- acquisition rates. The optical pulses may excite samples in reaction chambers of the instrument, and be used to generate a reference clock for operating signal-acquisition and signal-processing electronics of the instrument.

公开(公告)号：EP3099896A4

公开(公告)日：2017-12-06

申请号：EP14881279

申请日：2014-12-11

Applicant: SERVICES PÉTROLIERS SCHLUMBERGER ,  SCHLUMBERGER HOLDINGS ,  SCHLUMBERGER TECHNOLOGY BV

Inventor： SPECK ANDREW J ,  POMERANTZ ANDREW E ,  MULLINS OLIVER C

IPC: G01N21/17 ,  E21B49/08

CPC classification number: G01N21/1702 ,  G01N2021/1704 ,  G01N2021/1708 ,  G01N2201/06113 ,  G01N2201/0697 ,  G02F1/39

Abstract: A method for downhole fluid analysis by optical spectroscopy with photoacoustic detection includes positioning a photoacoustic system within a wellbore, applying a laser pulse to the fluid sample using the pulsed laser system, detecting, by the acoustic sensor, a time-resolved acoustic pulse generated by absorption of the laser pulse by the fluid sample, and determining a property of the fluid sample using the detected time resolved acoustic pulse. The photoacoustic system includes a pulsed laser system and an acoustic sensor.

公开(公告)号：EP3046141B1

公开(公告)日：2017-07-05

申请号：EP14844691.7

申请日：2014-09-10

Applicant: Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd.)

Inventor： HAYASHI, Kazushi ,  KISHI, Tomoya

IPC: H01L21/66 ,  G01N21/64 ,  G01N22/00

CPC classification number: G01N21/6489 ,  G01N22/00 ,  G01N2201/06113 ,  G01N2201/0697 ,  H01L22/12

公开(公告)号：EP3118665A1

公开(公告)日：2017-01-18

申请号：EP16178657.9

申请日：2016-07-08

Applicant: Olympus Corporation

Inventor： UE, Yoshihiro ,  NISHIWAKI, Daisuke ,  OKAZAKI, Kenya ,  ONO, Osamu ,  SUZUKI, Shingo

IPC: G02B21/02 ,  G02B21/24

CPC classification number: G02B21/367 ,  G01N21/41 ,  G01N2201/06113 ,  G01N2201/0638 ,  G01N2201/0697 ,  G01N2201/12 ,  G02B21/02 ,  G02B21/24 ,  G06T11/206 ,  G06T11/60

Abstract: A microscopy system includes a microscope apparatus (100,20;200,20:300,20) that has an objective (110) and a correction device (111) correcting for a spherical aberration, and a refractive index calculator (20d) that calculates a refractive index of a sample (S) at a target position in the sample (S) on the basis of a plurality of target set values each of which is a set value of the correction device (111) and each of which corresponds to an amount of spherical aberration that occurs in the microscope apparatus (100,20;200,20:300,20) when an observation target plane is situated at a different position in the sample (S) in an optical-axis direction of the objective (110).

Abstract translation: 显微镜系统包括具有物镜（110）和矫正装置（111）校正球面像差的显微镜装置（100,20; 200,20：300,20）和计算出的球面像差的折射率计算器（20d） 基于多个目标设定值，其中每个目标设定值是校正装置（111）的设定值，并且每个目标设定值对应于所述样本（S）的目标位置的样本（S）的折射率， 当观察目标平面位于物体的光轴方向上的样品（S）中的不同位置时，在显微镜装置（100,20; 200,20：300,20）中发生的球面像差的量（ 110）。

公开(公告)号：EP2961441A4

公开(公告)日：2016-10-19

申请号：EP14757680

申请日：2014-02-14

Applicant: STERIS INC ,  INST NAT OPTIQUE

Inventor： ROCHETTE DANIEL ,  GALLANT PASCAL ,  MERMUT OZGE ,  BARIBEAU FRANCOIS ,  NOISEUX ISABELLE ,  GOSSELIN ISABELLE

IPC: A61L2/28 ,  G01N21/64 ,  G01N21/94

CPC classification number: G01N21/6428 ,  A61L2/28 ,  A61L2202/24 ,  G01N21/6486 ,  G01N21/94 ,  G01N2021/6417 ,  G01N2021/6439 ,  G01N2201/06113 ,  G01N2201/068 ,  G01N2201/0697 ,  G01N2201/10 ,  G01N2201/105

Abstract: A method and apparatus for optical detection of residual soil on articles (such as medical instruments and equipment), after completion of a washing or a rinsing operation by a washer. A soil detection system provides an indication of soil on the articles by detecting luminescent radiation emanating from the soil in the presence of ambient light.

公开(公告)号：EP3074758A1

公开(公告)日：2016-10-05

申请号：EP14808560.8

申请日：2014-11-27

Applicant: Roche Diabetes Care, Inc. ,  F. Hoffmann-La Roche AG

Inventor： ALBRECHT, Gertrud ,  BAUMANN, Edgar ,  GENTHNER-RIEGLER, Markus ,  KALVERAM, Stefan ,  NIESPOREK, Christian ,  SCHWENKER, Kai-Oliver ,  SERR, Markus ,  WEHOWSKI, Frederic ,  WETTENGEL, Klaus

IPC: G01N21/84 ,  G01N21/78 ,  G01N33/487 ,  G01J3/433 ,  G01N21/47 ,  G01N21/27

CPC classification number: G01N21/75 ,  G01J3/433 ,  G01N21/274 ,  G01N21/4738 ,  G01N21/78 ,  G01N21/8483 ,  G01N33/48707 ,  G01N33/4875 ,  G01N2021/7786 ,  G01N2201/0612 ,  G01N2201/0621 ,  G01N2201/0697

Abstract: Methods, analytical devices and analytical systems are provided for determining at least one analyte concentration in a body fluid sample. The methods, which may be incorporated into the devices and systems, can include the following steps: applying a body fluid to a test carrier; illuminating the test carrier by at least one light source, where the at least one light source is modulated by using at least two modulation frequencies; receiving light remitted by the test carrier by using at least one detector; determining an analyte concentration by evaluating at least one detector signal generated by the detector, where the detector signal is demodulated with the at least two modulation frequencies to generate at least two demodulated detector signals, each demodulated signal corresponding to one of the modulation frequencies; and detecting a fault by comparing the at least two demodulated detector signals.

公开(公告)号：EP2443503B1

公开(公告)日：2015-12-23

申请号：EP10734059.8

申请日：2010-06-17

Applicant: W.O.M. World of Medicine GmbH

Inventor： SCHÖNBORN, Karl-Heinz

IPC: G02B21/00 ,  A61B5/00 ,  G01N21/64

CPC classification number: G01N21/6486 ,  A61B5/0059 ,  A61B5/0062 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/443 ,  A61B5/445 ,  A61B2562/0242 ,  G01N21/6458 ,  G01N2201/06113 ,  G01N2201/0697 ,  G01N2201/08 ,  G02B21/0028 ,  G02B21/0036 ,  G02B21/0076

公开(公告)号：EP2741072A4

公开(公告)日：2015-07-08

申请号：EP12819852

申请日：2012-07-31

Applicant: JAPAN SCIENCE & TECH AGENCY

Inventor： SHIGEKAWA HIDEMI ,  TAKEUCHI OSAMU

IPC: G01N21/17 ,  B82Y35/00 ,  G01N21/55 ,  G01N21/63 ,  G01Q60/12 ,  H01J37/244 ,  H01J37/26

CPC classification number: G01N21/55 ,  B82Y35/00 ,  G01N21/1717 ,  G01N21/636 ,  G01N2021/1719 ,  G01N2021/1725 ,  G01N2021/1789 ,  G01N2021/1791 ,  G01N2201/0697 ,  G01Q60/12 ,  H01J37/244 ,  H01J37/26 ,  H01J2237/24507 ,  H01J2237/24564 ,  H01J2237/2818

Abstract: A pump probe measuring device (1) comprises: an ultrashort optical pulse laser generator (2) for generating a first ultrashort optical pulse train which is a pump light (3a), second and third ultrashort optical pulse trains (3b), (3c) which are probe lights; an optical shutter unit (6) to which the second and the third ultrashort pulse trains (3b), (3c) are introduced; and a detecting unit (20) including an irradiation optical system (8) for directing the pump light (3a), the first probe light (3b) and the second probe light (3c) to a sample (7), a sensor (11) for detecting a probe signal from the sample (7), and a phase-sensitive detecting means (12) connected to the sensor (11). An optical shutter control unit (10) periodically modulates the delay time of the first probe light (3b) and that of the second probe light (3c) with respect to the pump light (3a), and the modulated first and second probe lights (3a), (3b) illuminate the sample (7) alternately to detect the probe signals from the sample (7) by the phase-sensitive detecting means (12) in synchronization with the periodic modulation signal of the delay time.

公开(公告)号：EP2847575A1

公开(公告)日：2015-03-18

申请号：EP13723261.7

申请日：2013-04-23

Applicant: Canon Kabushiki Kaisha

Inventor： KOIZUMI, Takayuki ,  KUBOTA, Oichi

IPC: G01N21/35 ,  G01N21/95

CPC classification number: G01N21/3586 ,  A61B5/0507 ,  A61B2562/14 ,  G01N21/3563 ,  G01N21/3581 ,  G01N21/9508 ,  G01N2201/06113 ,  G01N2201/0697 ,  G01N2201/08

Abstract: Provided is a measuring apparatus, including: an irradiation unit (101) configured to irradiate an object to be examined (111) with an electromagnetic wave, preferably in a range from 30 GHz to30 THz; a window member (110) configured to be brought into contact with the object to be examined; a sensing unit (102) configured to sense the electromagnetic wave from the object to be examined that is brought into contact with the window member; and a dielectric constant adjusting unit (108) configured to change a dielectric constant of the window member.

公开(公告)号：EP2232271A4

公开(公告)日：2014-12-10

申请号：EP08873367

申请日：2008-12-18

Applicant: SINGULEX INC

Inventor： LIVINGSTON RICHARD A

IPC: G01N35/00 ,  B01L3/00 ,  G01N15/00 ,  G01N15/14 ,  G01N21/64 ,  G01N33/53

CPC classification number: G01N21/6428 ,  B01L3/5085 ,  B01L2300/0654 ,  B01L2300/0829 ,  G01N15/14 ,  G01N15/1434 ,  G01N15/1456 ,  G01N15/1463 ,  G01N21/00 ,  G01N21/01 ,  G01N21/64 ,  G01N21/645 ,  G01N33/53 ,  G01N2015/0038 ,  G01N2015/1447 ,  G01N2015/1452 ,  G01N2201/02 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/0697

Abstract: The invention encompasses analyzers and analyzer systems that include a single molecule analyzer, methods of using the analyzer and analyzer systems to analyze samples, either for single molecules or for molecular complexes. The single molecule uses electromagnetic radiation that is translated through the sample to detect the presence or absence of a single molecule. The single molecule analyzer provided herein is useful for diagnostics because the analyzer detects single molecules with zero carryover between samples.

Abstract translation: 本发明包括分析仪和分析仪系统，其包括单分子分析仪，使用分析仪和分析仪系统分析样品的单分子或分子复合物的方法。 单分子使用通过样品翻译的电磁辐射来检测单个分子的存在或不存在。 本文提供的单分子分析仪可用于诊断，因为分析仪检测到样品之间具有零携带的单分子。