公开(公告)号：EP1388340A4

公开(公告)日：2004-12-08

申请号：EP02769547

申请日：2002-05-08

Applicant: KANEKA CORP

Inventor： FUJII KENJI ,  KAWABE TAIZO ,  HOSOE KAZUNORI ,  HIDAKA TAKAYOSHI

IPC: A23L1/30 ,  A61K9/00 ,  A61K9/02 ,  A61K9/22 ,  A61K31/047 ,  A61K31/09 ,  A61K31/122 ,  A61P1/00 ,  A61P1/04 ,  A61P3/10 ,  A61P9/10 ,  A61P11/02 ,  A61P27/02 ,  A61P27/14 ,  A61P37/08 ,  A61P43/00 ,  A61K9/06 ,  A61K9/08 ,  A61K9/70 ,  A61P25/00

CPC classification number: A61K31/122 ,  A23L33/10 ,  A23V2002/00 ,  A61K9/0031 ,  A61K9/0048 ,  A61K9/02 ,  A61K31/047 ,  A61K31/09 ,  Y10S514/882 ,  A61K2300/00 ,  A23V2250/314

Abstract: Concerning the supply of coenzyme Q which is highly useful in maintaining human health, it is intended to provide a method and preparations whereby coenzyme Q can be efficiently supplied to patients having difficulties in oral administration, aged having swallowing difficulties and patients with diseases caused by topical disorders. It is found out that the coenzyme Q concentration in the blood or topical mucosae can be elevated by using compositions for transmucosal administration containing oxidized coenzyme Q and/or reduced coenzyme Q as the active ingredient wherein the total content of the oxidized coenzyme Q and the reduced coenzyme Q amounts to 0.0001 to 99% by weight of the whole compositions.

Abstract translation: 关于对保持人体健康非常有用的辅酶Q的供给，意图提供一种方法和制剂，其中辅酶Q可以有效地供给给口服困难的患者，吞咽困难的老年人和患有由局部引起的疾病的患者 障碍。 已发现，通过使用含有氧化型辅酶Q和/或还原型辅酶Q作为活性成分的经粘膜给药组合物，可以提高血液或局部粘膜中的辅酶Q浓度，其中氧化型辅酶Q和还原型辅酶Q的总含量 辅酶Q占全部组合物重量的0.0001至99％。

公开(公告)号：EP1032263B1

公开(公告)日：2004-06-09

申请号：EP98958028.7

申请日：1998-11-16

Applicant: Woodward Laboratories Inc.

Inventor： DYER, David, L. ,  GERENRAICH, Kenneth, B.

IPC: A01N33/12 ,  A61K31/14

CPC classification number: A61Q11/00 ,  A01N33/12 ,  A61K8/40 ,  A61K8/416 ,  A61K8/442 ,  A61K31/14 ,  A61K2800/596 ,  A61Q3/00 ,  A61Q17/005 ,  A61Q19/10 ,  Y10S514/882 ,  Y10S514/887 ,  Y10S514/901 ,  Y10S514/944 ,  Y10S514/966 ,  Y10S514/967 ,  Y10S514/975 ,  A01N2300/00

公开(公告)号：EP0624375B1

公开(公告)日：2002-04-24

申请号：EP94301083.5

申请日：1994-02-15

Applicant: Novartis AG ,  UCP GEN-PHARMA AG

Inventor： Arvinte, Tudor

IPC: A61K35/62 ,  A61K38/58 ,  A61K9/08 ,  A61K47/02

CPC classification number: A61K47/02 ,  A61K9/0014 ,  A61K9/0019 ,  A61K38/58 ,  A61K47/26 ,  Y10S514/882 ,  Y10S514/97

公开(公告)号：EP0391905B1

公开(公告)日：1997-09-03

申请号：EP88907455.5

申请日：1988-07-06

Applicant: PACKMAN, Elias W.

Inventor： PACKMAN, Elias W.

IPC: A61K31/715

CPC classification number: A61K9/0031 ,  A61K31/70 ,  Y10S514/882

Abstract: Hemorrhoidal compositions containing disaccharide polysulfate-aluminum compounds such as sucralfate, alone or in combination with other hemorrhoidal products, as an agent effective for alleviating the symptoms of anorectal disease when topically applied to the human skin. Method for alleviating the symptoms of hemorrhoids in humans. Compositions containing disaccharide polysulfate-aluminum compounds such as sucralfate, alone or in combination with antibiotics, antifungal agents, anti-acne agents, or local anesthetics as an active agent effective in promoting the healing of wounds which are not anorectal when topically applied to the surface of a wound. Method for promoting healing at the surface of a wound in humans.

公开(公告)号：EP0752863A1

公开(公告)日：1997-01-15

申请号：EP95915223.0

申请日：1995-03-29

Applicant: UNIVERSITE PARIS-VAL DE MARNE

Inventor： BARRITAULT, Denis ,  CARUELLE, Jean-Pierre ,  MEDDAHI, Anne

IPC: A61K38 ,  A61K31 ,  A61P1 ,  A61P7 ,  A61P43

CPC classification number: A61K31/715 ,  Y10S514/882 ,  Y10S514/925 ,  Y10S514/926 ,  Y10S514/927

Abstract: The use of at least one polymer or biopolymer known as HBGFPP, capable of specifically protecting growth factors of families FGF and beta-TGF from trypsin damage, for preparing a drug for treating injuries to the digestive tract and the primary or secondary derived tissues of the entoderm and mesoderm, is disclosed.

公开(公告)号：EP0583482A1

公开(公告)日：1994-02-23

申请号：EP93903319.7

申请日：1993-02-05

Applicant: KAKEN PHARMACEUTICAL CO., LTD. ,  TORAY INDUSTRIES, INC.

Inventor： OKUMURA, Makoto, Cent. Research Lab. Kaken Pharm. ,  OKUDA, Toshiaki Cent. Research Lab. Kaken Pharm. ,  NAKAMURA, Tsutomu, Cent. Research Lab. Kaken Phar ,  YAMIJA, Motoyuki, Cent. Lab. Kaken Pharm. Co. Ltd

IPC: A61K31/557 ,  A61K31/34 ,  C07D307/935 ,  C07D307/77

CPC classification number: A61K31/5575 ,  A61K31/557 ,  A61K31/5585 ,  Y10S514/882 ,  Y10S514/925 ,  Y10S514/928

Abstract: A remedy for wounds or hemorrhoids, in particular, an external preparation containing at least one member selected among prostaglandin I₂, prostaglandin E₁ and derivatives thereof, in particular, beroprost, one of the prostaglandin I₂ derivatives, or a salt thereof as the active ingredient; and a therapy for wounds or hemorrhoids characterized by administering the above active ingredient.

Abstract translation: 伤口或痔疮的补救措施，特别是包含选自前列腺素I2，前列腺素E1及其衍生物，特别是前列腺素I2衍生物或其盐之一的贝前列素或其盐作为活性成分的至少一种成分的外用制剂; 以及用于施用上述活性成分的伤口或痔疮治疗。

公开(公告)号：EP0451182B1

公开(公告)日：1993-03-31

申请号：EP90900941.7

申请日：1989-12-29

Applicant: EDKO TRADING AND REPRESENTATION COMPANY LIMITED

Inventor： MORTON, Oswald ,  EMBIL, Koral

IPC: A61K9/02 ,  A61K9/107 ,  A61K9/50

CPC classification number: A61K9/025 ,  A61K9/0031 ,  Y10S514/882 ,  Y10S514/966

Abstract: The invention provides a multiphase pharmaceutical composition for combatting an anorectal disease comprising at least one phase containing one or more medicaments for combatting said disease and at least one phase adapted for delayed release of a silicone oil whereby application of said composition at a region affected by said disease deposits said medicament or medicaments thereon and a layer of silicone oil is formed thereover, so protecting the medicaments from erosion by aqueous media.

公开(公告)号：EP0510947A1

公开(公告)日：1992-10-28

申请号：EP92303614.9

申请日：1992-04-22

Applicant: ELI LILLY AND COMPANY

Inventor： Hite, Gary Alan ,  Mihelich, Edward David ,  Snyder, David Wells ,  Suarez, Tulio

IPC: C07C323/47 ,  A61K31/17 ,  C07C275/64

CPC classification number: C07C335/40 ,  C07C275/64 ,  Y10S514/825 ,  Y10S514/826 ,  Y10S514/863 ,  Y10S514/882 ,  Y10S514/885

Abstract: This invention relates to N-hydroxy-N-[3-(2-substituted phenyl)prop-2-enyl]ureas and thioureas, formulations containing those compounds, and methods of using such compounds as 5-lipoxygenase inhibiting agents.

Abstract translation: 本发明涉及N-羟基-N- [3-（2-取代苯基）丙-2-烯基]脲和硫脲，含有这些化合物的制剂，以及使用这些化合物作为5-脂氧合酶抑制剂的方法。

公开(公告)号：EP1383520B1

公开(公告)日：2013-09-18

申请号：EP02721902.1

申请日：2002-04-23

Applicant: Smith & Nephew (Overseas) Limited

Inventor： BURRELL, Robert, Edward ,  NAYLOR, Antony, George ,  MOXHAM, Peter, Howard

IPC: A61K33/00 ,  A61K33/24 ,  A61K33/38 ,  A61K33/40 ,  A61K9/00 ,  A61K9/08 ,  A61K9/12 ,  A61K9/14 ,  A61K9/70 ,  A61P1/02 ,  A61P11/02 ,  A61P11/04 ,  A61P43/00 ,  A61P29/00

CPC classification number: A61K9/0024 ,  A01N59/16 ,  A61K9/0019 ,  A61K9/0075 ,  A61K9/0078 ,  A61K9/14 ,  A61K9/7007 ,  A61K33/24 ,  A61K33/38 ,  A61K33/40 ,  A61K47/34 ,  A61K47/38 ,  A61L15/46 ,  A61L17/145 ,  A61L27/30 ,  A61L29/10 ,  A61L31/082 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/452 ,  A61L2300/606 ,  A61L2300/624 ,  A61L2300/63 ,  Y10S424/15 ,  Y10S514/825 ,  Y10S514/826 ,  Y10S514/829 ,  Y10S514/83 ,  Y10S514/849 ,  Y10S514/851 ,  Y10S514/853 ,  Y10S514/861 ,  Y10S514/862 ,  Y10S514/864 ,  Y10S514/865 ,  Y10S514/88 ,  Y10S514/881 ,  Y10S514/882 ,  Y10S514/886 ,  Y10S514/887 ,  Y10S514/90 ,  Y10S514/901 ,  Y10S514/902 ,  Y10S514/912 ,  Y10S514/914 ,  Y10S514/925 ,  Y10S514/931 ,  Y10S514/932 ,  Y10S514/933 ,  Y10S514/934 ,  Y10S514/944 ,  Y10S514/951 ,  Y10S514/953 ,  Y10S514/954 ,  Y10S514/956 ,  Y10S514/958 ,  Y10S514/964 ,  Y10S514/965 ,  Y10S514/966 ,  Y10S514/967 ,  Y10S514/968 ,  Y10S514/969 ,  Y10T428/31855 ,  A61K2300/00 ,  A01N25/04 ,  A01N25/10 ,  A01N25/12

公开(公告)号：EP2490666A1

公开(公告)日：2012-08-29

申请号：EP09850491.3

申请日：2009-12-11

Applicant: ASA Bullion Investment Limited

Inventor： LEI, William

IPC: A61K8/98 ,  A61K8/27 ,  A61K8/97 ,  A61Q19/00 ,  C11D1/00 ,  C11D3/12 ,  C11D3/382 ,  C11D3/384

CPC classification number: A61K36/886 ,  A61K8/27 ,  A61K8/925 ,  A61K8/97 ,  A61K33/30 ,  A61Q19/005 ,  Y10S514/882

Abstract: A cleansing lotion composition of zinc derivatives, aloe vera, lanolin and a mixture of water-based emulsifying agents for reducing itchiness, promoting healing and reducing inflammation around the anorectal area of a human subject is disclosed. The subject conveniently spreads a suitable amount of the cleansing lotion placed on toilet paper and applies to the affected anorectal area. The excess lotion could be wiped clean with fresh toilet paper after each application.