公开(公告)号：JP2009079035A

公开(公告)日：2009-04-16

申请号：JP2008202324

申请日：2008-08-05

Applicant: Bayer Ag ,  バイエル アクチェンゲゼルシャフトBayer Aktiengesellschaft

Inventor： LIEB FOLKER ,  FISCHER REINER ,  BRETSCHNEIDER THOMAS ,  RUTHER MICHAEL ,  GRAFF ALAN ,  SCHNEIDER UDO ,  ERDELEN CHRISTOPH ,  WACHENDORF-NEUMANN ULRIKE ,  ANDERSCH WOLFRAM ,  TURBERG ANDREAS

IPC: C07D207/38 ,  A01N43/08 ,  A01N43/10 ,  A01N43/16 ,  A01N43/36 ,  A01N43/84 ,  A01P7/02 ,  A01P7/04 ,  C07C57/34 ,  C07C57/58 ,  C07C59/64 ,  C07C59/88 ,  C07C69/612 ,  C07C69/65 ,  C07C69/66 ,  C07C69/734 ,  C07C69/74 ,  C07C69/757 ,  C07C205/49 ,  C07C229/42 ,  C07C233/14 ,  C07C233/21 ,  C07C233/39 ,  C07C233/50 ,  C07C233/51 ,  C07C233/52 ,  C07C235/36 ,  C07C255/29 ,  C07C255/45 ,  C07C255/57 ,  C07C323/50 ,  C07D20060101 ,  C07D209/54 ,  C07D209/96 ,  C07D213/53 ,  C07D231/56 ,  C07D307/60 ,  C07D307/94 ,  C07D309/14 ,  C07D313/04 ,  C07D333/50 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14 ,  C07D405/04 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D417/14 ,  C07D491/10 ,  C07D493/06 ,  C07D493/10

CPC classification number: C07D417/14 ,  C07C57/34 ,  C07C57/58 ,  C07C59/64 ,  C07C59/88 ,  C07C69/65 ,  C07C69/734 ,  C07C69/757 ,  C07C233/51 ,  C07C233/52 ,  C07C235/36 ,  C07C255/29 ,  C07C2601/14 ,  C07D207/38 ,  C07D209/96 ,  C07D231/56 ,  C07D307/94 ,  C07D309/14 ,  C07D313/04 ,  C07D333/50 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14 ,  C07D405/04 ,  C07D405/14 ,  C07D409/14 ,  C07D491/10 ,  C07D493/10

Abstract: PROBLEM TO BE SOLVED: To provide compounds which are 1-H-3-aryl-2,4-dione derivatives and are highly active against plant pests. SOLUTION: Provided are compounds of formula (I') (wherein X is chlorine, bromine, or methyl; Z is chlorine or methyl; and A and B are each a 1-8C alkyl, a 2-4C alkenyl, a (1-6C)alkoxy(1-4C)alkyl, a poly(1-4C)alkoxy(1-4C)alkyl, or a (1-6C)alkylthio(1-4C)alkyl, or a like group, provided that A and B may be combined with each other to form a ring). COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 待解决的问题：提供1-H-3-芳基-2,4-二酮衍生物并对植物害虫具有高度活性的化合物。 解决方案：提供式（I'）的化合物（其中X是氯，溴或甲基; Z是氯或甲基; A和B各自是1-8C烷基，2-4C烯基， （1-6C）烷氧基（1-4C）烷基，聚（1-4C）烷氧基（1-4C）烷基或（1-6C）烷硫基（1-4C）烷基等）基团，条件是 A和B可以彼此组合以形成环）。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP3256502B2

公开(公告)日：2002-02-12

申请号：JP31363198

申请日：1998-11-04

IPC: G01N33/15 ,  A61K20060101 ,  A61K31/13 ,  A61K31/135 ,  A61K31/14 ,  A61K31/16 ,  A61K31/165 ,  A61K31/235 ,  A61K31/275 ,  A61K31/395 ,  A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61K31/44 ,  A61K31/55 ,  A61K31/554 ,  A61K31/715 ,  A61K31/785 ,  A61K33/06 ,  A61K38/00 ,  A61K38/16 ,  A61K45/00 ,  A61P3/00 ,  A61P3/14 ,  A61P5/18 ,  A61P5/22 ,  A61P9/00 ,  A61P9/12 ,  A61P19/08 ,  A61P19/10 ,  A61P43/00 ,  C07C211/02 ,  C07C211/03 ,  C07C211/15 ,  C07C211/16 ,  C07C211/17 ,  C07C211/19 ,  C07C211/26 ,  C07C211/27 ,  C07C211/29 ,  C07C211/30 ,  C07C211/42 ,  C07C215/46 ,  C07C215/48 ,  C07C215/50 ,  C07C215/52 ,  C07C217/54 ,  C07C217/56 ,  C07C217/58 ,  C07C217/60 ,  C07C219/14 ,  C07C225/16 ,  C07C229/38 ,  C07C233/05 ,  C07C235/34 ,  C07C235/44 ,  C07C237/22 ,  C07C237/30 ,  C07C255/24 ,  C07C255/45 ,  C07C255/58 ,  C07C279/14 ,  C07C323/18 ,  C07C323/32 ,  C07D209/14 ,  C07D209/16 ,  C07D209/18 ,  C07D209/30 ,  C07D209/40 ,  C07D211/90 ,  C07D213/28 ,  C07D213/36 ,  C07D213/38 ,  C07D215/12 ,  C07D215/14 ,  C07D233/54 ,  C07D257/02 ,  C07D281/10 ,  C07D295/00 ,  C07D413/04 ,  C07H21/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/435 ,  C07K14/705 ,  C08G69/10 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12Q1/02 ,  C12R1/91 ,  G01N20060101 ,  G01N33/50 ,  G01N33/566 ,  G01N33/567 ,  G01N33/574 ,  G01N33/68 ,  G01N33/84

Abstract: Method and composition useful for treating a patient having a disease characterized by an abnormal level of one or more components, the activity of which is regulated or affected by activity of one or more Ca 2+ receptors. Novel compounds useful in these methods and compositions are also provided. The method includes administering to the patient a therapeutically effective amount of a molecule active at one or more Ca 2+ receptors as an agonist or antagonist. Preferably, the molecule is able to act as either a selective agonist or antagonist at a Ca 2+ receptor of one or more but not all cells chosen from the group consisting of parathyroid cells, bone osteoclasts, juxtaglomerular kidney cells, proximal tubule kidney cells, keratinocytes, parafollicular thyroid cells and placental throphoblasts and a pharmaceutically acceptable carrier.

公开(公告)号：JPH10237000A

公开(公告)日：1998-09-08

申请号：JP5704697

申请日：1997-02-25

Applicant: CHISSO CORP

Inventor： KOIZUMI YASUYUKI ,  YANO HITOSHI

IPC: G02F1/13 ,  C07C43/192 ,  C07C43/225 ,  C07C255/45 ,  C07D239/26 ,  C09K19/04 ,  C09K19/42

Abstract: PROBLEM TO BE SOLVED: To obtain a liquid crystal compound having low viscosity, negative dielectric anisotropy and excellent optical anisotropy, voltage-retention, stability and compatibility and useful for liquid crystal display element, etc., by introducing a specific group into a skeleton structure. SOLUTION: The compound has a group of C(CF3 )2 G and/or GC(CF3 )2 [G is O, a (1-10C alkyl-substituted)imino, etc.] in the skeleton structure and is expressed by the formula [R and Y are each a 1-20C alkyl, H, a halogen cyano, etc.; X to X are each (CH2 )2 , CH=CH, C≡C, COO, C(CF3 )2 G, etc.; the rings A to A are each trans-cyclohexane-1,4-diyl, cyclohex-1-ene-1,4-diyl, 1,4-phenylene, etc.; a to a are each 0 or 1; a +a +a +a +a >=1].

公开(公告)号：JPH10236990A

公开(公告)日：1998-09-08

申请号：JP6001897

申请日：1997-02-27

Applicant: CHISSO CORP

Inventor： MIYAZAWA KAZUTOSHI ,  YANO HITOSHI

IPC: G02F1/13 ,  C07C17/18 ,  C07C23/18 ,  C07C23/20 ,  C07C25/18 ,  C07C43/225 ,  C07C45/30 ,  C07C69/75 ,  C07C69/753 ,  C07C69/76 ,  C07C69/773 ,  C07C69/90 ,  C07C255/45 ,  C07C255/46 ,  C07F7/08 ,  C09K19/04 ,  C09K19/30 ,  C09K19/42

Abstract: PROBLEM TO BE SOLVED: To obtain a low-viscosity liquid crystal compound suitable for a liquid crystal display element, excellent in negative anisotropic value of dielectric constant, optical anisotropy, voltage retention, stability and compatibility, containing a difluorocyclohexadienediyl group in a skeleton structure. SOLUTION: This liquid crystal compound containing a 2,3- difluorocyclohexa-1,3-diene-1,4-diyl group in a skeleton structure is shown by the formula [R and Y are each a 1-20C alkyl, H, a halogen, cyano, cyanic acid, etc.; X to X are each a single bond, (CH2 )2 , CH=CH, C to A are each 2,3-diflyuorocyclohexa-1,3-diene-1,4-diyl, trans- cyclohexene-1,4-diyl, 1,4-phenylene, etc.; a to a are each 0 or 1; a +a +a +a + a >=1].

公开(公告)号：JPH10147544A

公开(公告)日：1998-06-02

申请号：JP30658696

申请日：1996-11-18

Applicant: SUMITOMO CHEMICAL CO

Inventor： FUJIMOTO YUKARI ,  MIYAMOTO YASUNOBU ,  MINAMII MASAYOSHI

IPC: G02F1/13 ,  B01J31/24 ,  C07C22/08 ,  C07C25/24 ,  C07C43/188 ,  C07C69/753 ,  C07C69/773 ,  C07C255/45 ,  C07D239/26 ,  C09K19/08

Abstract: PROBLEM TO BE SOLVED: To obtain a fluoroalkenyl compound useful for liquid crystal compositions and liquid crystal devices using them by introducing a F atom at an allyl site of an alkenyl group. SOLUTION: This liquid crystal composition used for liquid crystal devices comprises a compound of formula I (R is H, cyano, etc.; R is a 1-12C alkyl, etc.; R is 1-12 alkyl, etc.; A -A are each formula II, etc.; Z -Z are each -C=C-, -CH-CH-, etc.; X -X are each CH, CF, etc.; Y -Y are each H or F; (n) is 1-4; (m), (p) and (q) are each 0 or 1), which is produced by condensation reaction of a compound of the formula: R -(A -Z )p -(A -Z )q -A -Z -D (D is -C=CH, etc.) with a compound of formula III (E is a halogen, etc.) at temperature in the range of -70 to 100 deg.C, preferably -45 to 80 deg.C, in a solvent inactive to the reaction, for example, ether-based solvent, such as diethyl ether, or hydrocarbons.

公开(公告)号：JPH09291050A

公开(公告)日：1997-11-11

申请号：JP10564896

申请日：1996-04-25

Applicant: SUMITOMO CHEMICAL CO

Inventor： FUJIMOTO YUKARI ,  MIYAMOTO YASUNOBU ,  MINAMII MASAYOSHI

IPC: G02F1/13 ,  C07C25/24 ,  C07C43/18 ,  C07C255/45 ,  C07D239/26 ,  C09K19/12 ,  C09K19/14 ,  C09K19/20 ,  C09K19/30 ,  C09K19/34

Abstract: PROBLEM TO BE SOLVED: To obtain a new fluorovinylene derivative having low viscosity and broad liquid crystal phase and useful as a component of a liquid crystal composition. SOLUTION: This fluorovinylene derivative is expressed by formula I [R is H, F, cyano or R (O)m (R is an alkyl, an alkenyl or an alkynyl); A to A are each group of formula II, formula III, etc.; Z to Z are each single bond, (CH2 )n , C≡C. CH=CH, CH2 O, COO, etc.; (n) is 1-4; (m), (p) and (q) are each 0 or 1; X to X are each CH, CF or N; Y and Y are each H or F; R is an alkyl or an alkoxyalkyl], e.g. 4-(1,2-difluoro-1-(E)-hexenyl)-1- trifluoromethanesulfonyloxybenzene. The compound of formula I can be produced e.g. by the condensation reaction of a compound of formula IV [D is (CH2 )n MgBr, C≡CH, OH, etc.] with a compound of formula V [E is a halogen, OSO2 R' (R' is an alkyl or phenyl), OH, etc.].

公开(公告)号：JPH08231468A

公开(公告)日：1996-09-10

申请号：JP32486395

申请日：1995-12-13

Applicant: UNITED KINGDOM GOVERNMENT

Inventor： SAGE IAN CHARLES ,  JENNER JOHN ANTHONY ,  KURMEIER HANS ADOLF ,  PAULUTH DETLEF ,  ESCHER KLAUS ,  POETSCH EIKE

IPC: C07C69/616 ,  C07C1/32 ,  C07C43/225 ,  C07C67/00 ,  C07C69/68 ,  C07C69/712 ,  C07C69/734 ,  C07C69/75 ,  C07C69/753 ,  C07C69/76 ,  C07C69/92 ,  C07C69/94 ,  C07C241/00 ,  C07C253/00 ,  C07C255/45 ,  C07C255/46 ,  C07C255/55 ,  C07D213/00 ,  C07D213/30 ,  C07D213/55 ,  C07D213/79 ,  C07D213/80 ,  C07D237/08 ,  C07D239/26 ,  C07D241/12 ,  C07D253/06 ,  C07D319/06 ,  C09K19/12 ,  C09K19/20 ,  C09K19/30 ,  C09K19/34 ,  C09K19/44 ,  C09K19/46 ,  G02F1/13

公开(公告)号：JPH07291876A

公开(公告)日：1995-11-07

申请号：JP18221994

申请日：1994-08-03

Applicant: RICOH KK

Inventor： KAWAHARA EMI ,  YAMADA IKUKO ,  SHIYOJI MASAYUKI ,  KOJIMA AKIO

IPC: G03G5/06 ,  C07C13/15 ,  C07C22/02 ,  C07C23/08 ,  C07C49/537 ,  C07C49/597 ,  C07C69/734 ,  C07C69/738 ,  C07C69/757 ,  C07C69/76 ,  C07C205/45 ,  C07C251/20 ,  C07C255/45

Abstract: PURPOSE:To obtain a new cyclopentadiene compound being an electron- transporting acceptor compound and useful for electrophoto-graphic photoreceptor, etc., having high sensitivity and good durability. CONSTITUTION:A compound of formula I [R1 and R4 are each H, a (substituted) alkyl, a (substituted)aromatic, a (substituted)heterocycle, a (substituted) alkoxycarbonyl, a (substituted)carbamoyl, etc.; R2 and R3 are each H, a (substituted)alkyl, a (substituted)aromatic or a (substituted)heterocycle; X is 0, C(A)(B)(A and B are each H, a halogen, cyano, etc.) or N-R5 (R5 is an alkyl, cyano, an aromatic, etc.), e.g. a compound of formula II. Furthermore, the compound of formula I is obtained by reacting, e.g. a ketone compound of formula III with a dione compound of formula IV in the presence of a basic catalyst.

公开(公告)号：JPH0710786B2

公开(公告)日：1995-02-08

申请号：JP1615984

申请日：1984-02-02

IPC: C07D251/34 ,  C07C41/00 ,  C07C41/16 ,  C07C43/02 ,  C07C43/192 ,  C07C43/225 ,  C07C43/247 ,  C07C45/00 ,  C07C47/00 ,  C07C47/575 ,  C07C49/00 ,  C07C49/84 ,  C07C50/34 ,  C07C51/00 ,  C07C62/00 ,  C07C67/00 ,  C07C69/00 ,  C07C69/92 ,  C07C201/00 ,  C07C205/27 ,  C07C207/04 ,  C07C217/08 ,  C07C217/76 ,  C07C217/78 ,  C07C217/84 ,  C07C241/00 ,  C07C245/04 ,  C07C245/06 ,  C07C245/08 ,  C07C253/00 ,  C07C255/45 ,  C07C255/49 ,  C07C301/00 ,  C07C303/22 ,  C07C303/32 ,  C07C309/01 ,  C07C309/41 ,  C07C313/00 ,  C07C323/19 ,  C07C323/20 ,  C07C323/21 ,  C07C323/34 ,  C07C323/35 ,  C07C323/65 ,  C07D213/30 ,  C07D295/08 ,  C07D307/42 ,  C07D309/06

公开(公告)号：JPH06510531A

公开(公告)日：1994-11-24

申请号：JP50465092

申请日：1992-08-21

IPC: G01N33/15 ,  A61K20060101 ,  A61K31/13 ,  A61K31/135 ,  A61K31/14 ,  A61K31/16 ,  A61K31/165 ,  A61K31/235 ,  A61K31/275 ,  A61K31/395 ,  A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61K31/44 ,  A61K31/55 ,  A61K31/554 ,  A61K31/715 ,  A61K31/785 ,  A61K33/06 ,  A61K38/00 ,  A61K38/16 ,  A61K45/00 ,  A61P3/00 ,  A61P3/14 ,  A61P5/18 ,  A61P5/22 ,  A61P9/00 ,  A61P9/12 ,  A61P19/08 ,  A61P19/10 ,  A61P43/00 ,  C07C211/02 ,  C07C211/03 ,  C07C211/15 ,  C07C211/16 ,  C07C211/17 ,  C07C211/19 ,  C07C211/26 ,  C07C211/27 ,  C07C211/29 ,  C07C211/30 ,  C07C211/42 ,  C07C215/46 ,  C07C215/48 ,  C07C215/50 ,  C07C215/52 ,  C07C217/54 ,  C07C217/56 ,  C07C217/58 ,  C07C217/60 ,  C07C219/14 ,  C07C225/16 ,  C07C229/38 ,  C07C233/05 ,  C07C235/34 ,  C07C235/44 ,  C07C237/22 ,  C07C237/30 ,  C07C255/24 ,  C07C255/45 ,  C07C255/58 ,  C07C279/14 ,  C07C323/18 ,  C07C323/32 ,  C07D209/14 ,  C07D209/16 ,  C07D209/18 ,  C07D209/30 ,  C07D209/40 ,  C07D211/90 ,  C07D213/28 ,  C07D213/36 ,  C07D213/38 ,  C07D215/12 ,  C07D215/14 ,  C07D233/54 ,  C07D257/02 ,  C07D281/10 ,  C07D295/00 ,  C07D413/04 ,  C07H21/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/435 ,  C07K14/705 ,  C08G69/10 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12Q1/02 ,  C12R1/91 ,  G01N20060101 ,  G01N33/50 ,  G01N33/566 ,  G01N33/567 ,  G01N33/574 ,  G01N33/68 ,  G01N33/84 ,  A61K37/02 ,  C07K15/06

Abstract: Method and composition useful for treating a patient having a disease characterized by an abnormal level of one or more components, the activity of which is regulated or affected by activity of one or more Ca 2+ receptors. Novel compounds useful in these methods and compositions are also provided. The method includes administering to the patient a therapeutically effective amount of a molecule active at one or more Ca 2+ receptors as an agonist or antagonist. Preferably, the molecule is able to act as either a selective agonist or antagonist at a Ca 2+ receptor of one or more but not all cells chosen from the group consisting of parathyroid cells, bone osteoclasts, juxtaglomerular kidney cells, proximal tubule kidney cells, keratinocytes, parafollicular thyroid cells and placental throphoblasts and a pharmaceutically acceptable carrier.