摘要:
PROBLEM TO BE SOLVED: To provide a resist composition excellent in lithographic characteristics and a pattern profile, a method for forming a resist pattern using the resist composition, a novel compound useful as an acid generator for the resist composition, and an acid generator.SOLUTION: The resist composition includes: a base component (A) the solubility of which with a developing solution changes by an action of an acid; and an acid generator component (B) which generates an acid by exposure, the acid generator component (B) including an acid generator (B1) having a group expressed by the formula (b1-1) in a cationic moiety. In the formula, R' represents a 1-6C alkyl group, 1-6C alkoxy group, 1-6C halogenated alkyl group, halogen atom, hydroxy group, -COOR", -OC(=O)R", hydroxyalkyl group or cyano group, R" represents a hydrogen atom or an alkyl group, and p represents an integer of 0 to 4.
摘要:
PROBLEM TO BE SOLVED: To provide a new agent for the treatment of diseases caused by nerve cell degeneration, etc., its active component, a method for the preparation of the active component, and a substance and technique necessary for the method. SOLUTION: It has been found that a compound selected from salvianolic acid B, its optical or geometrical isomer having an action similar to salvianolic acid B, their prodrugs, pharmacologically permissible salt and hydrate of the above compounds and their prodrugs has an action to effect the proliferation and/or differentiation of a neural stem cell while protecting the neural stem cell or its differentiated cell. The finding induces the development of an agent acting on the neural cell and containing these substances as active components, a method for acting on the neural cell by using the acting agent, a method for the preparation of liquid containing neural cell and produced by using the acting method, a liquid containing neural cell and produced by using the preparation method, and an agent for the treatment of diseases caused e.g. by neural cell degeneration by using the acting agent and/or the liquid containing the neural cell as active components. COPYRIGHT: (C)2006,JPO&NCIPI
摘要:
PROBLEM TO BE SOLVED: To provide a method whereby moxidectin is purified at a high cost efficiency without needing so long time and a high-purity final product is yielded. SOLUTION: A purification method for moxidectin comprises as follows: (a) moxidectin is dissolved in a first solvent to prepare a moxidectin solution; (b) the solution is concentrated at about 50°C or lower and then cooled to a temperature within a range of about 40-30°C; (c) a second solvent is added to the moxidectin solution; then, (d) the solution is stirred while the temperature is lowered into a range of about 30-10°C so as to precipitate moxidectin crystals from the moxidectin solution; (e) the crystals are filtered off from the solution; and (f) the crystals are dried. COPYRIGHT: (C)2005,JPO&NCIPI
摘要:
PURPOSE:To obtain a new aminoanthraquinone compound useful as an anti- tumor agent having reduced toxicity while retaining strong anti-tumor activity. CONSTITUTION:A compound of formula I [R is H, a lower alkyl or a lower alkoxy; R is H; R is H, OH, a lower alkyl, a lower alkoxy, thiol, a lower alkylthio, NH2, a primary or secondary lower alkylamino or R and R are bonded to form (CH2)nA-(A is O or S; n is 1-3); formula II is single bond or double bond; R is H or a lower alkyl when formula II is single bond and R is O when formula II is double bond; m is 0-3) or its pharmacologically permissible salt such as 1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]-5-hydroxy-8- methoxymethylanthraquinone-dihydrochloride. The compound is obtained by reacting a compound of formula III (R and R are H or an amino-protecting group; R is H or an OH-protecting group) with a compound of formula IV (X is a halogen) is the presence of an acid scavenger and deprotecting.