专利检索 ap:"Hamideh Zarrinmayeh" 第 1 页

1.

发明申请
Thiophene and furan compounds 失效
标题翻译：噻吩和呋喃化合物

公开(公告)号：US20070105852A1

公开(公告)日：2007-05-10

申请号：US10596419

申请日：2005-01-05

申请人： Ana Castano Mansanet , Esteban Dominguez-Manzanares , Ana Escribano , Maria Fernandez , William Hornback , Alma Jimenez-Aguado , Eric Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Zimmerman

发明人： Ana Castano Mansanet , Esteban Dominguez-Manzanares , Ana Escribano , Maria Fernandez , William Hornback , Alma Jimenez-Aguado , Eric Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Zimmerman

IPC分类号： A61K31/5377 , A61K31/665 , A61K31/497 , A61K31/506 , A61K31/433 , A61K31/4433 , A61K31/4436 , A61K31/425 , A61K31/453

CPC分类号： C07D307/68 , C07D333/38 , C07D409/10 , C07D417/10

摘要： The present invention relates to thiophene and furan compounds and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression.

摘要翻译： 本发明涉及噻吩和呋喃化合物及其药学上可接受的盐，并且还涉及它们在治疗精神分裂症，与精神分裂症相关的认知缺陷，阿尔茨海默病，阿尔茨海默氏型痴呆，轻度认知障碍或抑郁症中的用途。

2.

发明申请
SULPHONAMIDE DERIVATIVES 失效
标题翻译：磺酰胺衍生物

公开(公告)号：US20060030599A1

公开(公告)日：2006-02-09

申请号：US10447619

申请日：2003-05-29

申请人： Macklin Arnold , Stephen Baker , Thomas Bleisch , Buddy Cantrell , Ana Escribano , Ken Matsumoto , Tracey Mckennon , Paul Ornstein , Richard Simon , Edward Smith , Hamideh Zarrinmayeh , Dennis Zimmerman

发明人： Macklin Arnold , Stephen Baker , Thomas Bleisch , Buddy Cantrell , Ana Escribano , Ken Matsumoto , Tracey Mckennon , Paul Ornstein , Richard Simon , Edward Smith , Hamideh Zarrinmayeh , Dennis Zimmerman

IPC分类号： A61K31/5377 , A61K31/496 , A61K31/4439 , A61K31/426 , A61K31/421

CPC分类号： A61K31/18 , A61K31/381 , A61K31/41 , A61K31/42 , A61K31/4245 , A61K31/4418 , A61K31/451 , A61K31/455 , C07C307/08 , C07C311/03 , C07C311/04 , C07C311/05 , C07C311/06 , C07C311/09 , C07C311/14 , C07C311/16 , C07C311/24 , C07C311/29 , C07C311/39 , C07C311/53 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/42 , C07D207/277 , C07D211/18 , C07D211/28 , C07D213/42 , C07D213/81 , C07D213/82 , C07D239/26 , C07D257/04 , C07D261/08 , C07D261/10 , C07D261/18 , C07D271/06 , C07D277/24 , C07D277/28 , C07D277/56 , C07D277/66 , C07D279/02 , C07D307/12 , C07D307/52 , C07D307/68 , C07D307/71 , C07D333/16 , C07D333/20 , C07D333/22 , C07D333/28 , C07D333/34 , C07D333/38 , C07D333/58 , C07D333/68 , C07D409/04

摘要： Glutamate receptor function in a mammal may be potentiated using an effective amount of a compound of formula R1-L-NHSO2R2 I in which R1 represents an unsubstituted or substituted aromatic or heteroaromatic group; R2 represents (1-6C)alkyl, (3-6C)cycloalkyl, (1-6C)fluoroalkyl, (1-6C) chloroalkyl, (2-6C)alkenyl, (1-4C)alkoxy(1-4C)alkyl, phenyl which is unsubstituted or substituted by halogen, (1-4C)alkyl or (1-4C)alkoxy, or a group, of formula R3R4N in which R3 and R4 each independently represents (1-4C)alkyl or, together with the nitrogen atom to which they are attached form an azetidinyl, pyrrolidinyl, piperidinyl, morpholino, piperazinyl, hexahydroazepinyl or octahydroazocinyl group; and L represents a (2-4C)alkylene chain which is unsubstituted or substituted by one or two substituents selected independently from (1-6C)alkyl, aryl(1-6C)alkyl, (2-6C)alkenyl, aryl(2-6C)alkenyl and aryl, or by two substituents which, together with the carbon atom or carbon atoms to which they are attached form a (3-8C)carbocyclic ring; and pharmaceutically acceptable salts thereof. Also disclosed are novel compounds of formula I, processes for preparing them and pharmaceutical compositions containing them.

摘要翻译： 哺乳动物中的谷氨酸受体功能可以使用有效量的式α化合物进行增强化学式描述=“在线公式”末端=“引物”→R 1 - L-NHSO 2 2 在线公式描述=“在线公式”end =“tail”→>其中R 1 代表未取代或取代的芳族或杂芳族基团; （1-6C）烷基，（3-6C）环烷基，（1-6C）氟烷基，（1-6C）氯烷基，（2-6C）烯基，（1-4C）烷氧基（1-4C）烷基，未被取代或被卤素取代的苯基，（1-4C）烷基或（1-4C）烷氧基或式R 3的基团，其中R 3和R 4各自独立地表示（1-4C）烷基，或者与它们相连的氮原子一起形成一个氮杂环丁烷基，吡咯烷基，哌啶基，吗啉代，哌嗪基，六氢氮杂基或八氢az嗪基; （1-6C）烷基，（2-6C）烷基，（2-6C）烯基，芳基（2-甲基苯基）丙烯基， 6C）烯基和芳基，或两个与它们所连接的碳原子或碳原子一起形成（3-8C）碳环的取代基; 及其药学上可接受的盐。还公开了式I的新化合物，其制备方法和含有它们的药物组合物。

3.

发明授权
Sulphonamide derivatives 失效
标题翻译：磺酰胺衍生物

公开(公告)号：US06358981B1

公开(公告)日：2002-03-19

申请号：US09744414

申请日：2001-01-23

申请人： Macklin Brian Arnold , David Michael Bender , Andrew Hendley Fray , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： Macklin Brian Arnold , David Michael Bender , Andrew Hendley Fray , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： C07D23504

CPC分类号： C07D213/42 , C07C311/03 , C07C311/04 , C07D213/26 , C07D213/81 , C07D333/16 , C07D333/20

摘要： The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

摘要翻译： 本发明涉及使用某些磺酰胺衍生物增强谷氨酸受体功能。它还涉及新型磺酰胺衍生物，其制备方法和含有它们的药物组合物。

4.

发明授权
Heterocyclic sulphonamide derivatives 失效
标题翻译：杂环磺酰胺衍生物

公开(公告)号：US06355655B1

公开(公告)日：2002-03-12

申请号：US09744457

申请日：2001-01-23

申请人： Ana Maria Escribano , Winton Dennis Jones , Paul Leslie Ornstein , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： Ana Maria Escribano , Winton Dennis Jones , Paul Leslie Ornstein , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： A61K31445

CPC分类号： C07D207/09 , C07D211/28

摘要： The present invention relates to the potentiation of glutamate receptor function using certain heterocyclic sulphonamide derivatives. It also relates to novel heterocyclic sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

摘要翻译： 本发明涉及使用某些杂环磺酰胺衍生物增强谷氨酸受体功能。它还涉及新型杂环磺酰胺衍生物，其制备方法和含有它们的药物组合物。

5.

发明授权
Sulfonamide derivatives 失效
标题翻译：磺酰胺衍生物

公开(公告)号：US06703425B2

公开(公告)日：2004-03-09

申请号：US10276738

申请日：2002-11-15

申请人： James Allen Knobelsdorf , Timothy Alan Shepherd , Eric George Tromiczak , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： James Allen Knobelsdorf , Timothy Alan Shepherd , Eric George Tromiczak , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： A61K3118

CPC分类号： C07D213/42 , C07C311/05 , C07C2601/14 , C07D235/14 , C07D333/20

摘要： The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders

摘要翻译： 本发明涉及可用于治疗与谷氨酸功能减退有关的病症的式（I）化合物或其药学上可接受的盐，例如精神和神经障碍

6.

发明授权
Amidophosphate derivatives 失效
标题翻译：酰胺磷酸酯衍生物

公开(公告)号：US06521605B1

公开(公告)日：2003-02-18

申请号：US09744411

申请日：2001-01-23

申请人： Macklin Brian Arnold , Paul Leslie Ornstein , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： Macklin Brian Arnold , Paul Leslie Ornstein , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： A61K3166

CPC分类号： C07F9/2475 , C07F9/58 , C07F9/59 , C07F9/6506 , C07F9/650952 , C07F9/6539 , C07F9/65515 , C07F9/655345 , C07F9/655354

摘要： The present invention provides amidophosphate derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.

摘要翻译： 本发明提供了可用于增强哺乳动物中谷氨酸受体功能的酰胺磷酸酯衍生物，因此可用于治疗各种各样的病症，例如精神病和神经障碍。

7.

发明授权
Sulphonamide derivatives 失效
标题翻译：磺酰胺衍生物

公开(公告)号：US06515026B2

公开(公告)日：2003-02-04

申请号：US10052988

申请日：2002-01-18

申请人： Macklin Brian Arnold , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： Macklin Brian Arnold , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： A61K3118

CPC分类号： C07D213/42 , C07C311/03 , C07C311/04 , C07D213/26 , C07D213/81 , C07D333/16 , C07D333/20

摘要： The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to process for their preparation and to pharmaceutical compositions containing them.

摘要翻译： 本发明涉及使用某些磺酰胺衍生物增强谷氨酸受体功能。它还涉及新型磺酰胺衍生物，其制备方法和含有它们的药物组合物。

8.

发明授权
Heterocyclyl sulphonamide derivatives 失效
标题翻译：杂环磺酰胺衍生物

公开(公告)号：US06358982B1

公开(公告)日：2002-03-19

申请号：US09744460

申请日：2001-01-23

申请人： Buddy Eugene Cantrell , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： Buddy Eugene Cantrell , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： A61K31445

CPC分类号： C07D211/26 , C07D211/22 , C07D211/28 , C07D211/76

摘要： The present invention relates to the potentiation of glutamate receptor function using certain heterocyclyl sulphonamide derivatives. It also relates to novel heterocyclyl sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

摘要翻译： 本发明涉及使用某些杂环基磺酰胺衍生物增强谷氨酸受体功能。它还涉及新的杂环基磺酰胺衍生物，其制备方法和含有它们的药物组合物。